Displaying drugs 551 - 575 of 1131 in total
Vadadustat
One of the most common symptoms of advanced renal disease is anemia, caused primarily by the inability of the kidney to respond to anemic conditions with a corresponding increase in erythropoietin (EPO) production. The treatment of anemia associated with chronic kidney disease (CKD) has traditionally involved the administration of exogenous...
Approved
Investigational
Matched Synonyms: … N-(5-(3-Chlorophenyl)-3-hydroxypyridine-2-carbonyl)glycine ... Glycine, N-((5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl)carbonyl)- …
Matched Description: … [A244165] Vadadustat is an orally administered inhibitor of HIF-PH with a safety and efficacy profile ... [A244165] A relatively new and alternative treatment option for patients with anemia associated with ... efficacious, the overuse of ESAs has been associated with cardiovascular complications, progression of CKD, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors …
Matched Description: … [A244165] Vadadustat is an orally administered inhibitor of HIF-PH with a safety and efficacy profile ... [A244165] A relatively new and alternative treatment option for patients with anemia associated with ... efficacious, the overuse of ESAs has been associated with cardiovascular complications, progression of CKD, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors …
Mecbotamab vedotin
Mecbotamab vedotin is an anti-Axl humanized monoclonal antibody conjugated to monomethyl auristatin E using a cleavable linker (CAB-Axl-ADC).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (DE-450-LYSINE), ANTI-(HUMAN TYROSINE KINASE RECEPTOR AXL) (HUMAN-MUS MUSCULUS MONOCLONAL …
Liothyronine
Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine. The exogenous liothyronine product was developed...
Approved
Vet approved
Matched Synonyms: … O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine ... 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine …
Matched Description: … [T457] The exogenous liothyronine product was developed by King Pharmaceuticals and FDA approved in 1956 ... Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Insulins ... combinations of levothyroxine and liothyronine …
Matched Description: … [T457] The exogenous liothyronine product was developed by King Pharmaceuticals and FDA approved in 1956 ... Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Insulins ... combinations of levothyroxine and liothyronine …
ACV tripeptide
Experimental
Matched Synonyms: … delta(L-2-Aminoadipyl)-L-cysteinyl-D-valine ... L-delta-(alpha-Aminoadipoyl)-L-cysteinyl-D-valine ... N-[L-5-Amino-5-carboxypentanoyl]-L-cysteinyl-D-valine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N-Acetylalanine
Experimental
Matched Synonyms: … N-acetyl-L-alanine ... N-Acetyl-S-alanine ... N-acetyl-L-α-alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Methadone
Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Matched Description: … However, it also has a unique pharmacokinetic profile. ... Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate ... of serotonin and norepinephrine uptake. …
Matched Salts name: … Methadone hydrochloride …
Matched Products: … Methadone Hydrochloride ... Methadone hydrochloride ... Methadone Hydrocloride …
Matched Salts name: … Methadone hydrochloride …
Matched Products: … Methadone Hydrochloride ... Methadone hydrochloride ... Methadone Hydrocloride …
Ropeginterferon alfa-2b
Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term propensity for myelofibrosis and leukemia.[A242000, A242005] Interferon alfa-2b has been used for decades to treat PV but requires frequent dosing...
Approved
Investigational
Matched Synonyms: … Pegylated proline interferon alpha-2b ... Pegylated proline-interferon alpha-2b …
Matched Description: … A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from proline-IFN-α ... platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term ... propensity for myelofibrosis and leukemia. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from proline-IFN-α ... platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term ... propensity for myelofibrosis and leukemia. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
LTI-03
LTI-03 is a caveolin-1 Scaffolding Domain 7-Mer
Investigational
Matched Synonyms: … L-threonine, l-phenylalanyl-l-threonyl-l-threonyl-l-phenylalanyl-l-threonyl-l-valyl- …
Leucine Phosphonic Acid
Experimental
Matched Name: … Leucine Phosphonic Acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
L-methionine sulfone
Experimental
Matched Synonyms: … Methionine sulfone …
Matched Name: … L-methionine sulfone …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … L-methionine sulfone …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Hydralazine
Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a...
Approved
Matched Description: … Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and ... hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and ... [T691]
Hydralazine hydrochloride was FDA approved on 15 January 1953.[L8779] …
Matched Mixtures name: … Isosorbide dinitrate and hydralazine hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride …
Matched Salts name: … Hydralazine hydrochloride …
Matched Categories: … hydralazine and diuretics ... Hydrazinophthalazine Derivatives and Diuretics …
Matched Products: … Hydralazine Hydrochloride ... HydrALAZINE Hydrochloride ... Apresoline hydrochloride …
Matched Mixtures name: … Isosorbide dinitrate and hydralazine hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride …
Matched Salts name: … Hydralazine hydrochloride …
Matched Categories: … hydralazine and diuretics ... Hydrazinophthalazine Derivatives and Diuretics …
Matched Products: … Hydralazine Hydrochloride ... HydrALAZINE Hydrochloride ... Apresoline hydrochloride …
Kelatorphan
Experimental
Matched Synonyms: … (3-(N-Hydroxy)carboxamido-2-benzylpropanoyl)alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Glutathione
A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
Approved
Investigational
Nutraceutical
Matched Synonyms: … gamma-L-Glutamyl-L-cysteinyl-glycine ... GLYCINE, L-.GAMMA.-GLUTAMYL-L-CYSTEINYL- ... N-(N-gamma-L-Glutamyl-L-cysteinyl)glycine …
Matched Description: … for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Chromium histidinate
Investigational
Matched Name: … Chromium histidinate …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Fluphenazine
A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Approved
Matched Description: … Its properties and uses are generally similar to those of chlorpromazine. …
Matched Salts name: … Fluphenazine hydrochloride …
Matched Products: … Fluphenazine Hydrochloride ... Fluphenazine hydrochloride ... Fluphenazine Hydrochoride …
Matched Salts name: … Fluphenazine hydrochloride …
Matched Products: … Fluphenazine Hydrochloride ... Fluphenazine hydrochloride ... Fluphenazine Hydrochoride …
Nicardipine
A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
Approved
Investigational
Matched Description: … It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without ... It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents …
Matched Salts name: … Nicardipine Hydrochloride …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … VALNIC ... Nicardipine Hydrochloride ... NICARDIPINE HYDROCHLORIDE …
Matched Salts name: … Nicardipine Hydrochloride …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … VALNIC ... Nicardipine Hydrochloride ... NICARDIPINE HYDROCHLORIDE …
Dexmedetomidine
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and …
Matched Salts name: … Dexmedetomidine hydrochloride …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Dexmedetomidine Hydrochloride ... Dexmedetomidine hydrochloride ... Dexmedetomidine Hydrochloride in Dextrose …
Matched Salts name: … Dexmedetomidine hydrochloride …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Dexmedetomidine Hydrochloride ... Dexmedetomidine hydrochloride ... Dexmedetomidine Hydrochloride in Dextrose …
Foslevodopa
Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants With Advanced Parkinson's Disease).
Approved
Investigational
Matched Synonyms: … 3-hydroxy-O-phosphono-L-tyrosine …
Matched Description: … Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and …
Matched Categories: … Dopa and Dopa Derivatives ... foslevodopa and decarboxylase inhibitor …
Matched Description: … Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and …
Matched Categories: … Dopa and Dopa Derivatives ... foslevodopa and decarboxylase inhibitor …
Displaying drugs 551 - 575 of 1131 in total