Displaying drugs 576 - 600 of 2385 in total
Garcinia gummi-gutta fruit
Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
DCLL-9718S
DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Zilucoplan
Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … -GLUTAMYL-L-TYROSYL-L-PROLYL-(2S)-2-CYCLOHEXYLGLYCYL-N6-(3 ... -GLUTAMYL-L-ARGINYL-L-PHENYLALANYL-L-.ALPHA.-ASPARTYL-N-METHYL-L-.ALPHA. ... -GLUTAMYL-L-ARGINYL-L-PHENYLALANYL-L-.ALPHA.-ASPARTYL-N-METHYL-L-.ALPHA.-ASPARTYL-3-METHYL- …
Matched Iupac: … 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72-tetracosaoxapentaheptacontan-75-amido}hexanoic acid …
Matched Description: … Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72-tetracosaoxapentaheptacontan-75-amido}hexanoic acid …
Matched Description: … Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
(S)-2-Tetrahydrofuroic acid
Experimental
Matched Synonyms: … (R)-(+)-Tetrahydro-2-furoic acid ... (S)-(-)-2-Tetrahydrofuroic acid ... (2R)-Tetrahydro-2-furancarboxylic acid …
Matched Name: … (S)-2-Tetrahydrofuroic acid …
Matched Iupac: … (2R)-oxolane-2-carboxylic acid …
Matched Name: … (S)-2-Tetrahydrofuroic acid …
Matched Iupac: … (2R)-oxolane-2-carboxylic acid …
Bismuth subsalicylate
Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Description: … of [salicylic acid] linked to trivalent [bismuth cation]. ... Bismuth subsalicylate is an antacid and anti-diarrheal agent. ... to relieve nausea, diarrhea, and gastrointestinal discomfort. …
Matched Mixtures name: … Pepto-Bismol and Pepto-Bismol To Go ... Pepto-Bismol and Pepto-Bismol To Go …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Products: … Up and Up Stomach Relief ... Up and Up Digestive Relief ... Foster and Thrive Stomach Relief …
Matched Mixtures name: … Pepto-Bismol and Pepto-Bismol To Go ... Pepto-Bismol and Pepto-Bismol To Go …
Matched Categories: … Antacids and Adsorbents ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Products: … Up and Up Stomach Relief ... Up and Up Digestive Relief ... Foster and Thrive Stomach Relief …
Lamotrigine
Lamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It...
Approved
Investigational
Matched Description: … It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. ... Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval ... [A191350]
Lamotrigine has relatively few side-effects and does not require laboratory monitoring. …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … LAMOTRIGIN ACIS 25MG ... LAMOTRIGIN ACIS 50MG ... LAMOTRIGIN ACIS 100MG …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … LAMOTRIGIN ACIS 25MG ... LAMOTRIGIN ACIS 50MG ... LAMOTRIGIN ACIS 100MG …
Diphenhydramine
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Description: … stings, and rashes [L5263, L5266, L5269, F3379]. ... However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. ... receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and …
Matched Mixtures name: … Up and Up Nighttime Flu and Severe Cold and Cough ... Up and Up Flu and Severe Cold and Cough Relief ... Flu and Severe Cold and Cough …
Matched Categories: … Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy ... Up and Up Nighttime Sleep-aid …
Matched Mixtures name: … Up and Up Nighttime Flu and Severe Cold and Cough ... Up and Up Flu and Severe Cold and Cough Relief ... Flu and Severe Cold and Cough …
Matched Categories: … Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy ... Up and Up Nighttime Sleep-aid …
Bisacodyl
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700]
Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Foster and Thrive Gentle Laxative …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Foster and Thrive Gentle Laxative …
Dabocemagene autoficel
Dabocemagene autoficel is an ex vivo, autologous cell-based gene therapy. It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen. Developed by Castle Creek Biosciences Inc., dabocemagene autoficel is being investigated for the treatment of dystrophic epidermolysis bullosa.
Investigational
Matched Synonyms: … AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING ... INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'-HUMAN CYTOMEGALOVIRUS PROMOTER/UTR-AND …
3-(N-morpholino)propanesulfonic acid
Experimental
Matched Synonyms: … 3-morpholinopropanesulfonic acid ... Morpholinopropane sulfonic acid …
Matched Name: … 3-(N-morpholino)propanesulfonic acid …
Matched Iupac: … 3-(morpholin-4-yl)propane-1-sulfonic acid …
Matched Name: … 3-(N-morpholino)propanesulfonic acid …
Matched Iupac: … 3-(morpholin-4-yl)propane-1-sulfonic acid …
Tannic acid
Tannic acid is a polyphenolic compound. It is a type of the commercially available tannins. It acts as a weak acid. Tannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria and other Quercus species). It is removed and used as medicine....
Approved
Matched Synonyms: … Tannic acid ... Gallotannic acid …
Matched Name: … Tannic acid …
Matched Description: … Tannic acid is also taken by mouth and applied directly for bleeding, chronic diarrhea, dysentery, bloody ... and poison ivy. ... It acts as a weak acid. …
Matched Name: … Tannic acid …
Matched Description: … Tannic acid is also taken by mouth and applied directly for bleeding, chronic diarrhea, dysentery, bloody ... and poison ivy. ... It acts as a weak acid. …
L-thioproline
Experimental
Matched Synonyms: … Thiazolidinecarboxylic acid ... (4R)-4-Thiazolidinecarboxylic acid ... (R)-4-Thiazolidinecarboxylic acid …
Matched Iupac: … (4R)-1,3-thiazolidine-4-carboxylic acid …
Matched Iupac: … (4R)-1,3-thiazolidine-4-carboxylic acid …
Loratadine
Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … Up and Up allergy and congestion relief ... Loratadine and Pseudoephedrine ... Smart Sense allergy and congestion relief indoor and outdoor allergies …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Childrens Allergy Relief …
Matched Mixtures name: … Up and Up allergy and congestion relief ... Loratadine and Pseudoephedrine ... Smart Sense allergy and congestion relief indoor and outdoor allergies …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Childrens Allergy Relief …
Methopterin
Methopterin is thought to have effects on osteoclasts and to inhibit inflammatory bone destruction.
Investigational
Matched Synonyms: … 10-methylfolic acid ... N10-methylfolic acid ... 10-methylpteroylglutamic acid …
Matched Iupac: … -2-[(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid …
Matched Description: … Methopterin is thought to have effects on osteoclasts and to inhibit inflammatory bone destruction. …
Matched Iupac: … -2-[(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid …
Matched Description: … Methopterin is thought to have effects on osteoclasts and to inhibit inflammatory bone destruction. …
Hadacidin
Experimental
Matched Synonyms: … N-hydroxyformamidoacetic acid ... N-formyl hydroxyaminoacetic acid ... N-formyl-N- hydroxyaminoacetic acid …
Matched Iupac: … 2-(N-hydroxyformamido)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … 2-(N-hydroxyformamido)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Tolevamer
Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched Synonyms: … polystyrenesulfonic acid ... Polystyrene sulfonic acid ... poly(styrene-4-sulfonic acid) …
Matched Description: … It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among ... It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Matched Description: … It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among ... It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Vorinostat
Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease persists, gets worse, or comes back during or after treatment with other medicines. It is the first...
Approved
Investigational
Matched Synonyms: … Suberanilohydroxamic acid ... Suberoylanilide hydroxamic acid ... Octanedioic acid hydroxyamide phenylamide …
Matched Description: … Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hydroxy Acids ... Carboxylic Acids ... Hydroxamic Acids …
Matched Description: … Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hydroxy Acids ... Carboxylic Acids ... Hydroxamic Acids …
Briquilimab
Briquilimab is a humanized aglycosylated IgG1 kappa monoclonal antibody targeting CD117 (cKit).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (297-GLUTAMINE), ANTI-(HUMAN C-KIT RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JSP191 …
Ceftezole
Experimental
Matched Iupac: … acetamido]-3-[(1,3,4-thiadiazol-2-ylsulfanyl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Products: … ALOMEN …
Matched Products: … ALOMEN …
Obeticholic acid
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … Obeticholic acid ... 6-ethylchenodeoxycholic acid ... 6α-ethylchenodeoxycholic acid …
Matched Name: … Obeticholic acid …
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Cholic Acids …
Matched Name: … Obeticholic acid …
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Cholic Acids …
Idroxioleic acid
Investigational
Matched Synonyms: … 2-hydroxyoleic acid ... Alpha-hydroxyoleic acid ... (z)-2-hydroxyoctadec-9-enoic acid …
Matched Name: … Idroxioleic acid …
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Matched Name: … Idroxioleic acid …
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Phenylboronic acid
Experimental
Matched Synonyms: … Borophenylic acid ... Benzeneboronic acid …
Matched Name: … Phenylboronic acid …
Matched Iupac: … phenylboronic acid …
Matched Categories: … Acids ... Acids, Noncarboxylic …
Matched Name: … Phenylboronic acid …
Matched Iupac: … phenylboronic acid …
Matched Categories: … Acids ... Acids, Noncarboxylic …
5,7-Dichlorokynurenic acid
Experimental
Matched Synonyms: … 5,7-Dichorokynurenic acid ... 5,7-Dichloroquinurenic acid …
Matched Name: … 5,7-Dichlorokynurenic acid …
Matched Iupac: … 5,7-dichloro-4-hydroxyquinoline-2-carboxylic acid …
Matched Categories: … Acids, Heterocyclic ... Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists …
Matched Name: … 5,7-Dichlorokynurenic acid …
Matched Iupac: … 5,7-dichloro-4-hydroxyquinoline-2-carboxylic acid …
Matched Categories: … Acids, Heterocyclic ... Excitatory Amino Acid Agents ... Excitatory Amino Acid Antagonists …
Displaying drugs 576 - 600 of 2385 in total