Displaying drugs 576 - 600 of 1997 in total
Cinnamic acid
Investigational
Matched Synonyms: … 2-propenoic acid, 3-phenyl- ... 3-phenyl-2-propenoic acid ... 2-propenoic acid, 3-phenyl-, (2e)- …
Matched Categories: … Heparin and similars …
Matched Categories: … Heparin and similars …
CB-103
CB-103 is under investigation in clinical trial NCT03422679 (Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies).
Investigational
Matched Synonyms: … 3-PYRIDINAMINE, 6-(4-(1,1-DIMETHYLETHYL)PHENOXY)- ... 6-(4-(1,1-Dimethylethyl)phenoxy)-3-pyridinamine …
Matched Description: … clinical trial NCT03422679 (Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and …
Matched Description: … clinical trial NCT03422679 (Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and …
Leflunomide
Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Approved
Investigational
Matched Synonyms: … 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)- ... 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide ... N-(4-(TRIFLUOROMETHYL)PHENYL) 5 METHYLISOXAZOLE-4-CARBOXAMIDE …
Matched Iupac: … 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide …
Matched Description: … drug) class of drugs, which are chemically and pharmacologically very heterogeneous. ... Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. ... Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Matched Iupac: … 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide …
Matched Description: … drug) class of drugs, which are chemically and pharmacologically very heterogeneous. ... Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. ... Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Betameprodine
Betameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred to as Meprodine). Betameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of opioids,...
Experimental
Illicit
Matched Synonyms: … beta-1-Methyl-3-ethyl-4-phenyl-4-propionoxy-piperidin ... beta-3-Ethyl-1-methyl-4-phenyl-4-propionoxypiperidine …
Matched Description: … as well as itching, nausea, and respiratory depression. ... The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
Matched Description: … as well as itching, nausea, and respiratory depression. ... The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
4-Phenyl-1h-Imidazole
Experimental
Matched Name: … 4-Phenyl-1h-Imidazole …
Matched Iupac: … 5-phenyl-1H-imidazole …
Matched Iupac: … 5-phenyl-1H-imidazole …
N-[2-Chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide
Experimental
Matched Synonyms: … 2-[2-Chloro-5-(trifluoromethyl)phenyl]-1-(diaminomethylene)guanidine …
Matched Name: … N-[2-Chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide …
Matched Iupac: … (E)-N''-[2-chloro-5-(trifluoromethyl)phenyl]-N-(diaminomethylidene)guanidine …
Matched Name: … N-[2-Chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide …
Matched Iupac: … (E)-N''-[2-chloro-5-(trifluoromethyl)phenyl]-N-(diaminomethylidene)guanidine …
Glatiramer
Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. Since glatiramer acetate is a heterogeneous drug, there is limited information about its physicochemical properties. Originally, glatiramer acetate was designed as a...
Approved
Investigational
Matched Synonyms: … Copolymer I (synthetic peptide) …
Matched Description: … is a first-line drug for patients with MS. ... , and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. ... [A248880] It was approved by the FDA in 1996, and a generic version became available in 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … is a first-line drug for patients with MS. ... , and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. ... [A248880] It was approved by the FDA in 1996, and a generic version became available in 2017. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Fitusiran
Fitusiran is under investigation in clinical trial NCT02554773 (An Open-label Extension Study of an Investigational Drug, ALN-AT3SC, in Patients With Moderate or Severe Hemophilia A or B).
Investigational
Matched Synonyms: … Synthetic double-stranded siRNA oligonucleotide against antithrombin mRNA …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Immucin
Investigational
Matched Synonyms: … Synthetic Signal Peptide Of Human Mucin-1 (Amino Acids 1-21) …
ANEB-001
ANEB-001 is under investigation in clinical trial NCT05282797 (Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CB1 Antagonist ANEB-001 in a THC Challenge Test).
Investigational
Matched Synonyms: … 1-AZETIDINECARBOXAMIDE, 3-((R)-(4-CHLOROPHENYL)(2-(TRIFLUOROMETHYL)PHENYL)METHOXY)-N-(1,1-DIMETHYLETHYL ... 3-((R)-(4-CHLOROPHENYL)(2-(TRIFLUOROMETHYL)PHENYL)METHOXY)-N-(1,1-DIMETHYLETHYL)-1-AZETIDINECARBOXAMIDE …
Matched Description: … ANEB-001 is under investigation in clinical trial NCT05282797 (Safety, Tolerability, Pharmacokinetics, and …
Matched Description: … ANEB-001 is under investigation in clinical trial NCT05282797 (Safety, Tolerability, Pharmacokinetics, and …
Ceritinib
Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of prior crizotinib therapy. About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like...
Approved
Matched Synonyms: … N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl} …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like 4) and ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Clobazam
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Synonyms: … 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine ... 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …
Matched Description: … Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis ... , Frisium, Urbanyl, and others. ... Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …
Matched Description: … Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis ... , Frisium, Urbanyl, and others. ... Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Procyclidine
A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
Approved
Matched Synonyms: … 1-Cyclohexyl-1-phenyl-3-pyrrolidino-1-propanol ... 1-cyclohexyl-1-phenyl-3-pyrrolidin-1-yl-propan-1-ol hydrochloride …
Matched Iupac: … 1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol …
Matched Description: … extrapyramidal disorders and in parkinsonism. ... A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced …
Matched Iupac: … 1-cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol …
Matched Description: … extrapyramidal disorders and in parkinsonism. ... A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced …
SP-876
Experimental
Matched Synonyms: … 1-[(4-{[(1S)-1,3-Dicarboxypropyl]carbamoyl}phenyl)sulfonyl]-D-prolyl-β-alanine …
Matched Iupac: … (2S)-2-[(4-{[(2R)-2-[(2-carboxyethyl)carbamoyl]pyrrolidin-1-yl]sulfonyl}phenyl)formamido]pentanedioic …
Matched Iupac: … (2S)-2-[(4-{[(2R)-2-[(2-carboxyethyl)carbamoyl]pyrrolidin-1-yl]sulfonyl}phenyl)formamido]pentanedioic …
Phenyl-uridine-5'-diphosphate
Experimental
Matched Name: … Phenyl-uridine-5'-diphosphate …
Matched Iupac: … 3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy(phenoxy …
Matched Iupac: … 3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy(phenoxy …
(4-(trifluoromethoxy)phenyl)urea
Experimental
Matched Name: … (4-(trifluoromethoxy)phenyl)urea …
Matched Iupac: … [4-(trifluoromethoxy)phenyl]urea …
Matched Iupac: … [4-(trifluoromethoxy)phenyl]urea …
Cerdulatinib
Cerdulatinib is under investigation in clinical trial NCT04021082 (CELTIC-1: A Phase 2B Study of Cerdulatinib in Patients With Relapsed/refractory Peripheral T-cell Lymphoma (PTCL)).
Investigational
Matched Synonyms: … 4-(cyclopropylamino)-2-((4-(4-(ethanesulfonyl)piperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide ... 5-pyrimidinecarboxamide, 4-(cyclopropylamino)-2-((4-(4-(ethylsulfonyl)-1-piperazinyl)phenyl)amino)- …
Matched Iupac: … 4-(cyclopropylamino)-2-({4-[4-(ethanesulfonyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamide …
Matched Iupac: … 4-(cyclopropylamino)-2-({4-[4-(ethanesulfonyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamide …
VAD-044
VAD-044 is an allosteric AKT inhibitor developed by Vaderis Therapeutics AG. It is being investigated for the treatment of Hereditary Hemorrhagic Telangiectasia.
Investigational
Matched Synonyms: … 6-(4-((1S,3S)-1-amino-3-hydroxycyclobutyl)phenyl)-1-ethyl-7-phenyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)- …
Matched Description: … It is being investigated for the treatment of Hereditary Hemorrhagic Telangiectasia.[L46098] …
Matched Description: … It is being investigated for the treatment of Hereditary Hemorrhagic Telangiectasia.[L46098] …
5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid
Investigational
Matched Synonyms: … 5-((trans-4-(4-(trifluoromethoxy)phenyl)cyclohexyl)oxy)-1h-1,2,3-triazole-4-carboxylic acid ... 5-[[trans-4-[(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid …
Matched Name: … 5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid …
Matched Iupac: … 5-{[(1r,4r)-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy}-1H-1,2,3-triazole-4-carboxylic acid …
Matched Name: … 5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid …
Matched Iupac: … 5-{[(1r,4r)-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy}-1H-1,2,3-triazole-4-carboxylic acid …
[3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid
Experimental
Matched Name: … [3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid …
Matched Iupac: … 2-[3,5-dibromo-4-(4-hydroxy-3-{hydroxy[(2-phenylethyl)amino]methyl}phenoxy)phenyl]ethane-1,1-diol …
Matched Iupac: … 2-[3,5-dibromo-4-(4-hydroxy-3-{hydroxy[(2-phenylethyl)amino]methyl}phenoxy)phenyl]ethane-1,1-diol …
Minaprine
Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
Approved
Matched Synonyms: … 4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholine ... N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine …
Matched Description: … amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Description: … amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
TG100-115
An NSAID that inhibits PI-3K gamma and delta.
Investigational
Matched Synonyms: … 3-(2,4-Diamino-6-(3-hydroxyphenyl)pteridin-7-yl)phenol …
Matched Iupac: … 3-[2,4-diamino-7-(3-hydroxyphenyl)pteridin-6-yl]phenol …
Matched Description: … An NSAID that inhibits PI-3K gamma and delta. …
Matched Iupac: … 3-[2,4-diamino-7-(3-hydroxyphenyl)pteridin-6-yl]phenol …
Matched Description: … An NSAID that inhibits PI-3K gamma and delta. …
Pterostilbene
Investigational
Matched Synonyms: … PHENOL, 4-((1E)-2-(3,5-DIMETHOXYPHENYL)ETHENYL)- …
Matched Iupac: … 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol …
Matched Iupac: … 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol …
Displaying drugs 576 - 600 of 1997 in total