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Displaying drugs 576 - 600 of 2962 in total
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …
Experimental
Matched Synonyms: … para-toluene sulfonate ... Tosic acid ... Tosylic acid
Matched Name: … p-Toluenesulfonic acid
Matched Iupac: … 4-methylbenzene-1-sulfonic acid
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Arylsulfonic Acids
Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Name: … Fenofibric acid
Matched Iupac: … 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid
Matched Description: … ], and other conjugated compounds of fenofibric acid, such as choline fenofibrate, have been developed ... , and mixed dyslipidemia. ... for improved solubility, gastrointestinal absorption, and bioavailability, and more convenient administration …
Matched Categories: … Acids, Acyclic ... Fibric Acids ... Carboxylic Acids
Matched Products: … Fenofibric Acid ... Fenofibric acid ... ACIDO FENOFIBRICO 135 MG …
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Synonyms: … Alendronic acid ... Acido Alendronico ... Acide Alendronique …
Matched Name: … Alendronic acid
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid
Matched Description: … osteoperosis and Paget's disease[FDA Label][A959,A203111]. ... Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of …
Matched Mixtures name: … ACIDO ALENDRONICO E COLECALCIFEROLO EG ... ACIDO ALENDRONICO E COLECALCIFEROLO EG ... ACIDO ALENDRONICO E COLECALCIFEROLO EG …
Matched Salts name: … Alendronate calcium ... Alendronate sodium ... Alendronate sodium anhydrous …
Matched Categories: … alendronic acid, calcium and colecalciferol, sequential ... alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential ... Drugs Affecting Bone Structure and Mineralization ... alendronic acid
Matched Products: … Alendronate Sodium ... Ag-alendronate Sodium ... Jamp Alendronate Sodium
An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and...
Approved
Matched Description: … It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic ... effects in movement disorders are not well understood but probably reflect an increase in synthesis and
Matched Salts name: … Amantadine sulfate ... Amantadine hydrochloride
Matched Products: … Amantadine Hydrochloride ... Amantadine hydrochloride ... Pdp-amantadine Hydrochloride Syrup …
Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Investigational
Matched Synonyms: … 6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-Sulfamate
Matched Iupac: … 6-oxo-6H,7H,8H,9H,10H,11H-cyclohepta[c]chromen-3-yl sulfamate
Matched Description: … Irosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast …
Matched Categories: … Steryl-Sulfatase, antagonists & inhibitors ... Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Experimental
Matched Name: … 3,6-Anhydro-2-(hydrogen sulfate)-alpha-D-galactopyranose …
Matched Iupac: … [(1R,3S,4R,5S,8S)-3,8-dihydroxy-2,6-dioxabicyclo[3.2.1]octan-4-yl]oxidanesulfonic acid
A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) Flavin adenine dinucleotide is approved for use in Japan under the trade name Adeflavin as an ophthalmic treatment for vitamin B2 deficiency.
Approved
Matched Synonyms: … Riboflavin 5'-adenosine diphosphate ... adenosine 5'-[3-(riboflavin-5'-yl) dihydrogen diphosphate] ... Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with riboflavine
Matched Iupac: … -2H,3H,4H,10H-benzo[g]pteridin-10-yl}-2,3,4-trihydroxypentyl]oxy}(hydroxy)phosphoryl)oxy]phosphinic acid
Matched Description: … A condensation product of riboflavin and adenosine diphosphate. ... ., D-amino acid oxidase and L-amino acid oxidase. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Enzymes and Coenzymes …
The chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Approved
Investigational
Matched Synonyms: … Calcio acetato ... Calcium acetate ... calcium ethanoate …
Matched Name: … Calcium acetate …
Matched Iupac: … calcium diacetate …
Matched Description: … The chemical compound calcium acetate is the calcium salt of acetic acid. ... The anhydrous form is very hygroscopic, therefore the monohydrate is the common form. …
Matched Salts name: … Calcium acetate monohydrate
Matched Categories: … ascorbic acid (vit C) and calcium ... calcium acetate and magnesium carbonate ... Alimentary Tract and Metabolism ... Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Calcium Salts …
Matched Products: … Calcium Acetate ... Calcium Acetate 667 mg ... Calcium Acetate Tab 667mg …
Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases...
Approved
Investigational
Matched Description: … Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads ... to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. ... The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases to …
Matched Salts name: … Alfuzosin hydrochloride
Matched Categories: … Genito Urinary System and Sex Hormones ... alfuzosin and finasteride …
Matched Products: … ALFUZOSIN ACINO 5MG RET ... ALFUZOSIN ACINO 10MG RET ... Alfuzosin Hydrochloride
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Synonyms: … 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester …
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine. ... FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol hydrochloride
Matched Salts name: … Esmolol hydrochloride
Matched Products: … Esmolol Hydrochloride In Sodium Chloride ... Esmolol Hydrochloride ... Esmolol Hydrochloride in Water …
Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O. It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then crystallizing the product to form a slightly pink powder. Manganese gluconate is a direct ingredient in food substances...
Approved
Matched Synonyms: … Manganese D-gluconate ... Manganese(II) gluconate ... Manganese gluconate anhydrous …
Matched Name: … Manganese gluconate …
Matched Iupac: … manganese(2+) bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) …
Matched Description: … It is typically obtained by reacting manganese carbonate with gluconic acid in aqueous medium and then ... Manganese gluconate is a manganese salt of gluconic acid with the chemical formula C12H22MnO14 x 2H2O ... Manganese gluconate is a direct ingredient in food substances as a nutrient supplement. …
Matched Mixtures name: … Iron Plus Manganese, B12, Folic Acid & C ... Cal-mag Plus K, Mn and Zn Caplets ... Multivitamins and Minerals for Young Men …
Matched Categories: … Sugar Acids ... Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids
Matched Products: … Manganese Caps 10mg ... Manganese (gluconate) 10 Mg Tablets …
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Synonyms: … [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester …
Matched Description: … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... the eye, ear, nose, and throat. ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse …
Matched Salts name: … Cocaine hydrochloride
Matched Categories: … Analgesics and Anesthetics ... Esters of Benzoic Acid
Matched Products: … Cocaine Hydrochloride ... Cocaine Hydrochloride Nasal ... Cocaine Hydrochloride Top Sol 40mg/ml …
Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb. Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) injury. Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with...
Approved
Withdrawn
Matched Description: … Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb …
Matched Salts name: … Nefazodone hydrochloride
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … Nefazodone hydrochloride ... Nefazodone Hydrochloride
Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
Approved
Matched Synonyms: … Sulfa-5-methoxypyrimidine …
Matched Description: … Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sulfonamides and trimethoprim ... Gynecological Antiinfectives and Antiseptics …
Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist,...
Approved
Vet approved
Matched Description: … , and even death. ... Frequently also carried by medical and emergency personnel and at events known to be associated with ... life-threatening symptoms such as respiratory depression, reduced heart rate, slurred speech, drowsiness, and
Matched Mixtures name: … Pentazocine Hydrochloride and Naloxone Hydrochloride ... Pentazocine Hydrochloride and Naloxone Hydrochloride ... Pentazocine and naloxone hydrochlorides
Matched Salts name: … Naloxone hydrochloride ... Naloxone hydrochloride dihydrate …
Matched Categories: … Alimentary Tract and Metabolism ... tilidine and naloxone ... oxycodone and naloxone ... pentazocine and naloxone ... hydromorphone and naloxone …
Matched Products: … Naloxone Hydrochloride ... Naloxone Hydrochloride Fine ... NALOXONE HYDROCHLORIDE
Experimental
Matched Synonyms: … Riboflavin tetrabutyrate ... Riboflavin 2',3',4',5'-tetrabutyrate ... Riboflavin, 2',3',4',5'-tetrabutanoate …
Matched Name: … Riboflavin tetrabutyrate …
Matched Categories: … Enzymes and Coenzymes …
In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Description: … with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. ... derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and ... Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Salts name: … Donepezil hydrochloride monohydrate ... Donepezil hydrochloride
Matched Categories: … donepezil, memantine and Ginkgo folium ... donepezil and memantine …
Matched Products: … DONEPEZIL HYDROCHLORIDE MONOHYDRATE ... ANDEM 10 MG FILM TABLET, 14 ADET ... ANDEM 10 MG FILM TABLET, 28 ADET …
Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD.[L7237,L7240,L7243,L7246] Clonidine was granted FDA approval on 3 September 1974.
Approved
Matched Description: … [A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD. …
Matched Salts name: … Clonidine hydrochloride
Matched Categories: … Antiglaucoma Preparations and Miotics ... clonidine and diuretics ... clonidine and diuretics, combinations with other drugs …
Matched Products: … Clonidine Hydrochloride ... Clonidine HYDROCHLORIDE ... Clonidine hydrochloride
Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant DNA origin. Galsulfase is a glycoprotein with a molecular weight of approximately 56 kD. The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation sites, four of which carry a bis mannose-6-phosphate...
Approved
Investigational
Matched Synonyms: … N-acetylgalactosamine-4-sulfatase, recombinant human …
Matched Description: … which is required for enzyme activity and is conserved in all members of the sulfatase enzyme family. ... The recombinant protein is comprised of 495 amino acids and contains six asparagine-linked glycosylation ... Galsufase is a variant form of the polymorphic human enzyme N-acetylgalactosamine 4-sulfatase of recombinant …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Chondroitinases and Chondroitin Lyases …
Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Matched Synonyms: … Carglumic acid ... Acide carglumique ... Acidum carglumicum …
Matched Name: … Carglumic acid
Matched Iupac: … (2S)-2-(carbamoylamino)pentanedioic acid
Matched Description: … Carglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010. ... cause neurologic problems, cerebral edema, coma, and death. ... disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and
Matched Categories: … Amino Acids and Derivatives ... Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids
Matched Products: … Carglumic Acid ... Carglumic acid ... ACIDO CARGLUMICO WAYMADE …
Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
Approved
Matched Iupac: … 1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Matched Description: … Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems. …
Matched Mixtures name: … Moexipril Hydrochloride and Hydrochlorothiazide ... Moexipril Hydrochloride and Hydrochlorothiazide ... Moexipril Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Moexipril Hydrochloride
Matched Categories: … ACE Inhibitors and Diuretics ... moexipril and diuretics …
Matched Products: … Moexipril Hydrochloride ... Moexipril hydrochloride
Experimental
Matched Name: … 8-epi-Cyanocobalamin
Matched Products: … Cyanocobalamin
An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Approved
Matched Description: … The compound exerts its antitumor effects by interference with the synthesis and function of DNA. …
Matched Salts name: … Epirubicin hydrochloride
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Epirubicin Hydrochloride ... Epirubicin hydrochloride ... EPIRUBICIN HYDROCHLORIDE
Dexmethylphenidate is the dextrorotary form of methylphenidate introduced in 2002 . It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant . It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD)[Label,A177181]. The d-isomer is thought to have greater effect with fewer side effects than the l-isomer or...
Approved
Investigational
Matched Description: … It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant[A177193]. …
Matched Salts name: … Dexmethylphenidate hydrochloride
Matched Categories: … Methylphenidate and isomer ... dexmethylphenidate and serdexmethylphenidate ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … Dexmethylphenidate Hydrochloride ... Dexmethylphenidate hydrochloride ... Dexmethylphenidate Hydrochloride Extended-Release …
Displaying drugs 576 - 600 of 2962 in total