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Displaying drugs 6101 - 6125 of 10369 in total
1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE
Experimental
Matched Name: … 1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE …
Matched Iupac: … 1-({2-[2-(4-chlorophenyl)ethyl]-1,3-dioxolan-2-yl}methyl)-1H-imidazole …
Matched Iupac: … 1-({2-[2-(4-chlorophenyl)ethyl]-1,3-dioxolan-2-yl}methyl)-1H-imidazole …
N-(Bromoacetyl)-beta-alanyl-N-(2-{4-[(carboxycarbonyl)amino]phenyl}ethyl)-L-serinamide
Experimental
Matched Synonyms: … 2-[4-[2-[[(2S)-2-[3-[(2-bromoacetyl)amino]propanoylamino]-3-hydroxypropanoyl]amino]ethyl]anilino]-2-oxoacetic ... N-(Bromoacetyl)-β-alanyl-N-(2-{4-[(carboxycarbonyl)amino]phenyl}ethyl)-L-serinamide …
Matched Name: … N-(Bromoacetyl)-beta-alanyl-N-(2-{4-[(carboxycarbonyl)amino]phenyl}ethyl)-L-serinamide …
Matched Iupac: … [(4-{2-[(2S)-2-[3-(2-bromoacetamido)propanamido]-3-hydroxypropanamido]ethyl}phenyl)carbamoyl]formic acid …
Matched Name: … N-(Bromoacetyl)-beta-alanyl-N-(2-{4-[(carboxycarbonyl)amino]phenyl}ethyl)-L-serinamide …
Matched Iupac: … [(4-{2-[(2S)-2-[3-(2-bromoacetamido)propanamido]-3-hydroxypropanamido]ethyl}phenyl)carbamoyl]formic acid …
Isatin
Isatin is an indole derivative first obtained by Erdman and Laurent in 1841 as an oxidation product of Indigo dye with nitric acid and chromic acids. The compound is found in many plants and Schiff bases of Isatin are have been investigated for pharmaceutical applications.
Experimental
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ebvaciclib
Ebvaciclib is under investigation in clinical trial NCT03519178 (A Study of PF-06873600 in People With Cancer).
Investigational
Matched Synonyms: … 6-(difluoromethyl)-8-((1r,2r)-2-hydroxy-2-methylcyclopentyl)-2-((1- (methylsulfonyl)piperidin-4-yl) amino ... Pyrido(2,3-d)pyrimidin-7(8h)-one, 6-(difluoromethyl)-8-((1r,2r)-2-hydroxy-2-methylcyclopentyl)-2-((1- …
2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
PhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) has been used in trials studying the basic science of Pancreas Cancer.
Investigational
Matched Synonyms: … 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine …
Matched Name: … 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine …
Matched Iupac: … 1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine …
Matched Description: … PhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) has been used in trials studying the basic science …
Matched Name: … 2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine …
Matched Iupac: … 1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine …
Matched Description: … PhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) has been used in trials studying the basic science …
A Disubstituted Succinyl Caprolactam Hydroxymate Mmp3inhibitor
Experimental
Matched Iupac: … (2S,3R)-N-hydroxy-2-(3-hydroxypropyl)-N'-[(3S)-1-(2-methoxyethyl)-2-oxoazepan-3-yl]-3-(2-methylpropyl …
(1S)-1-AMINO-2-(1H-INDOL-3-YL)ETHANOL
Experimental
Matched Name: … (1S)-1-AMINO-2-(1H-INDOL-3-YL)ETHANOL …
Matched Iupac: … (1S)-1-amino-2-(1H-indol-3-yl)ethan-1-ol …
Matched Iupac: … (1S)-1-amino-2-(1H-indol-3-yl)ethan-1-ol …
(R)-2-Hydroxy-3-Sulfopropanoic Acid
Experimental
Matched Name: … (R)-2-Hydroxy-3-Sulfopropanoic Acid …
Matched Iupac: … (2R)-2-hydroxy-3-sulfopropanoic acid …
Matched Iupac: … (2R)-2-hydroxy-3-sulfopropanoic acid …
4-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diol
Experimental
Matched Name: … 4-bromo-6-(6-hydroxy-1,2-benzisoxazol-3-yl)benzene-1,3-diol …
Matched Iupac: … 4-bromo-6-(6-hydroxy-1,2-benzoxazol-3-yl)benzene-1,3-diol …
Matched Iupac: … 4-bromo-6-(6-hydroxy-1,2-benzoxazol-3-yl)benzene-1,3-diol …
1,3,4,9-Tetrahydro-2-(Hydroxybenzoyl)-9-[(4-Hydroxyphenyl)Methyl]-6-Methoxy-2h-Pyrido[3,4-B]Indole
Experimental
Matched Name: … 1,3,4,9-Tetrahydro-2-(Hydroxybenzoyl)-9-[(4-Hydroxyphenyl)Methyl]-6-Methoxy-2h-Pyrido[3,4-B]Indole …
Matched Iupac: … 4-{9-[(4-hydroxyphenyl)methyl]-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-2-carbonyl}phenol …
Matched Iupac: … 4-{9-[(4-hydroxyphenyl)methyl]-1H,2H,3H,4H,9H-pyrido[3,4-b]indole-2-carbonyl}phenol …
Candoxatrilat
A dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy)propyl]cyclopentanecarboxylic acid. A potent inhibitor of neutral endopeptidase (NEP, neprilysin, EC 3.4.24.11), it is used as its 2,3-dihydro-1H-inden-5-yl ester prodrug in the treatment of chronic heart failure.
Experimental
Matched Iupac: … (1s,4s)-4-{1-[(2S)-2-carboxy-2-[(2-methoxyethoxy)methyl]ethyl]cyclopentaneamido}cyclohexane-1-carboxylic …
Matched Description: … carboxy-3-(2-methoxyethoxy)propyl]cyclopentanecarboxylic acid. ... inhibitor of neutral endopeptidase (NEP, neprilysin, EC 3.4.24.11), it is used as its 2,3-dihydro-1H-inden-5- ... group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2- …
Matched Description: … carboxy-3-(2-methoxyethoxy)propyl]cyclopentanecarboxylic acid. ... inhibitor of neutral endopeptidase (NEP, neprilysin, EC 3.4.24.11), it is used as its 2,3-dihydro-1H-inden-5- ... group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2- …
Valopicitabine
The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus...
Experimental
Matched Synonyms: … 2'-C-methylcytidine 3'-O-L-valinyl ester …
Matched Iupac: … 3-yl (2S)-2-amino-3-methylbutanoate ... (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- …
Matched Description: … The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus ... its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent ... Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into …
Matched Iupac: … 3-yl (2S)-2-amino-3-methylbutanoate ... (2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)-4-methyloxolan- …
Matched Description: … The 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus ... its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent ... Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into …
PRO-542
PRO 542 belongs to a new class of drugs, viral-entry inhibitor, which is intended to prevent HIV from entering and infecting cells. PRO 542 (CD4-immunoglobulin G2) is a tetravalent CD4-immunoglobulin fusion protein that broadly neutralizes primary HIV-1 isolates.
Investigational
AME-527
AME-527 is a humanized monoclonal antibody that recognizes human TNF-alpha (hTNF-alpha) with high affinity and specificity. AME-527 was generated by protein engineering and identified from a library of antibody variants based on its improved binding properties.
Investigational
ADP-597
JNJ-38431055 has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
Investigational
Matched Iupac: … propan-2-yl 4-({6-[(6-methanesulfonyl-2-methylpyridin-3-yl)amino]-5-methoxypyrimidin-4-yl}oxy)piperidine …
Matched Description: … JNJ-38431055 has been used in trials studying the treatment of Diabetes Mellitus, Type 2. …
Matched Description: … JNJ-38431055 has been used in trials studying the treatment of Diabetes Mellitus, Type 2. …
EPI-589
EPI-589 is under investigation in clinical trial NCT02460679 (Safety and Biomarker Study of EPI-589 in Participants With Amyotrophic Lateral Sclerosis (ALS)).
Investigational
Matched Iupac: … (2R)-2-hydroxy-2-methyl-4-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide …
E-52862
Investigational
Matched Iupac: … 4-(2-{[5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yl]oxy}ethyl)morpholine …
TRX-518
Investigational
LJP-539
Investigational
AMG-553
AMG-553 is an adoptive, anti-FLT3 chimeric antigen receptor T-cell therapy generated through transduction of autologous T-cells with a self-inactivating human immunodeficiency virus-1 based lentiviral vector.
Investigational
Sepantronium
Sepantronium is a compound that suppresses survivin expression in a dose and time-dependent manner, and causes broad-range apoptosis.
Investigational
Matched Synonyms: … 1h-naphth(2,3-d)imidazolium, 4,9-dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)- …
Matched Iupac: … 3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-[(pyrazin-2-yl)methyl]-1H,4H,9H-naphtho[2,3-d]imidazol-3-ium …
Matched Iupac: … 3-(2-methoxyethyl)-2-methyl-4,9-dioxo-1-[(pyrazin-2-yl)methyl]-1H,4H,9H-naphtho[2,3-d]imidazol-3-ium …
SXR-1096
Investigational
Matched Synonyms: … 4h-3,1-benzoxazin-4-one, 6-ethoxy-7-methoxy-2-(2-(methylthio)phenyl)- ... 6-ethoxy-7-methoxy-2-(2-methylsulfanylphenyl)-3,1-bensoxazin-4-one …
Matched Iupac: … 6-ethoxy-7-methoxy-2-[2-(methylsulfanyl)phenyl]-4H-3,1-benzoxazin-4-one …
Matched Iupac: … 6-ethoxy-7-methoxy-2-[2-(methylsulfanyl)phenyl]-4H-3,1-benzoxazin-4-one …
TC-5231
TC-5231 is a small molecule that has been under investigation as an oral treatment for ADHD (Attention Deficit/Hyperactivity Disorder). TC-5231 is mecamylamine hydrochloride, the active ingredient in FDA-approved product, Inversine, but in a lower dose than Inversine.
Investigational
ABT-510
ABT-510 is a peptide mimetic of thrombospondin-1 (TSP-1), blocks angiogenesis in vitro and in vivo, and slows tumor growth. It is developed by Abbott Laboratories for the treatment of Solid Tumors, Lymphoma and Melanoma.
Investigational
Matched Iupac: … (2S)-1-[(2S)-5-[(diaminomethylidene)amino]-2-[(2S,3S)-2-[(2S)-2-[(2S,3R)-3-hydroxy-2-[(2R,3S)-3-methyl ... -2-[(2S)-3-methyl-2-{2-[2-(N-methylacetamido)acetamido]acetamido}butanamido]pentanamido]butanamido]pentanamido ... ]-3-methylpentanamido]pentanoyl]-N-ethylpyrrolidine-2-carboxamide …
GS-5745
GS-5745 has been used in trials studying the treatment of Tumors, Breast Cancer, Crohn's Disease, Colorectal Cancer, and Pancreatic Cancer, among others.
Investigational
Displaying drugs 6101 - 6125 of 10369 in total