Displaying drugs 6126 - 6150 of 8282 in total
Atuliflapon
Atuliflapon is under investigation in clinical trial NCT05251259 (Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-severe Uncontrolled Asthma).
Investigational
Matched Description: … Atuliflapon is under investigation in clinical trial NCT05251259 (Study to Assess the Efficacy and Safety of …
Lerodalcibep
Lerodalcibep is under investigation in clinical trial NCT05004675 (Trial to Evaluate Efficacy and Safety of LIB003 and Inclisiran in High-risk CVD Patients).
Investigational
Matched Description: … Lerodalcibep is under investigation in clinical trial NCT05004675 (Trial to Evaluate Efficacy and Safety of …
Alphameprodine
Alphameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer betameprodine is similarly classified, however alphameprodine is more widely used (both are referred to as Meprodine). Alphameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of...
Experimental
Illicit
Matched Description: … Alphameprodine is a structural analogue of meperidine. ... an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
PEV3A
PEV3A is a prophylactic malaria vaccine that acts against various stages of the disease. It is a two-component vaccine that contains the virosome formulated peptide mimetics PEV301 and PEV302. The two synthetic peptide vaccine components mimic the native structure of important antigens of the malaria parasite. The elicited antibodies are...
Investigational
Matched Description: … The two synthetic peptide vaccine components mimic the native structure of important antigens of the ... PEV3A is a prophylactic malaria vaccine that acts against various stages of the disease. …
SGN-15
SGN-15 is studied in the treatment of cancer. It combines a monoclonal antibody with the anticancer drug doxorubicin. Monoclonal antibodies are substances that are made in the laboratory and that can locate and bind to cancer cells. Doxorubicin is a type of anthracycline antitumor antibiotic. When it is combined with...
Investigational
Matched Description: … SGN-15 is studied in the treatment of cancer. ... Doxorubicin is a type of anthracycline antitumor antibiotic. ... When it is combined with a monoclonal antibody, it forms a type of drug conjugate. …
GTI-2501
GTI-2501 is a novel antisense drug which has shown a favorable safety profile in preclinical studies, and in a phase I clinical trial. The drug is in a phase II clinical trial in combination with docetaxel for the treatment of hormone refractory prostate cancer. Initial testing has demonstrated strong antitumor...
Investigational
Matched Description: … has demonstrated strong antitumor activity in preclinical studies in prostate cancer and a variety of ... The drug is in a phase II clinical trial in combination with docetaxel for the treatment of hormone refractory …
Gaboxadol
Gaboxadol also known as 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol (THIP) is an experimental sleep aid drug developed by Lundbeck and Merck, who reported increased deep sleep without the reinforcing effects of benzodiazepines. Development of Gaboxadol was stopped in March 2007 after concerns regarding safety and efficacy. It acts on the GABA system, but in...
Investigational
Matched Description: … Development of Gaboxadol was stopped in March 2007 after concerns regarding safety and efficacy. ... developed by Lundbeck and Merck, who reported increased deep sleep without the reinforcing effects of …
Imidacloprid
Imidacloprid is a neonicotinoid, which is a class of neuro-active insecticides modeled after nicotine. Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and sold under trade names Kohinor, Admire, Advantage, Gaucho, Merit, Confidor, Hachikusan, Premise, Prothor, and Winner. It is marketed as pest...
Vet approved
Matched Description: … Imidacloprid is a neonicotinoid, which is a class of neuro-active insecticides modeled after nicotine ... Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer …
Sodium copper chlorophyllin
Sodium copper chlorophyllin (SCC) is a water-soluble and bright green mixture derived from natural chlorophyll that has potential antimutagenic and antioxidant properties . This compound is used as a food colorant and supplement .
SCC of the commercial-grade is prepared from a reaction between a crude chlorophyll extract and methanolic...
Investigational
Matched Description: … sodium hydroxide, followed by replacement of the central magnesium atom with a heavy metal[A227718]. ... SCC of the commercial-grade is prepared from a reaction between a crude chlorophyll extract and methanolic …
D-Alanine
The D-enantiomer of alanine.
Experimental
Matched Description: … The D-enantiomer of alanine. …
Ubenimex
Ubenimex (also known as bestatin) is a competitive protease inhibitor. It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. It is being studied for use in the treatment of acute myelocytic leukemia.
Investigational
Matched Description: … It is being studied for use in the treatment of acute myelocytic leukemia. ... It is an inhibitor of aminopeptidase B, leukotriene A4 hydrolase, aminopeptidase N. …
VTP-201227
VTP-201227 has a novel mechanism of action and is being developed as a topical agent for the treatment of psoriasis with potential extensions into other dermatological indications. It is being developed by Vitae Pharmaceuticals.
Investigational
Matched Description: … of psoriasis with potential extensions into other dermatological indications. ... VTP-201227 has a novel mechanism of action and is being developed as a topical agent for the treatment …
IPH 1101
IPH 1101 is a chemically-synthesized structural analog of non-conventional bacterial phosphoantigens which specifically activate the Vγ9Vδ2 T cell subset. IPH 1101 is the most advanced drug candidate of the γδ T cell platform
Investigational
Matched Description: … IPH 1101 is the most advanced drug candidate of the γδ T cell platform ... IPH 1101 is a chemically-synthesized structural analog of non-conventional bacterial phosphoantigens …
Trodusquemine
Trodusquemine, a spermine metabolite of cholesterol, is a naturally occurring aminosterol that inhibits protein tyrosine phosphatase 1B. It has demonstrated the ability to stimulate regeneration of heart and multiple other tissues in animal models .
Investigational
Matched Description: … Trodusquemine, a spermine metabolite of cholesterol, is a naturally occurring aminosterol that inhibits ... It has demonstrated the ability to stimulate regeneration of heart and multiple other tissues in animal …
Rineterkib
Rineterkib is an inhibitor of extracellular signal-regulated kinase (ERK) being investigated in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients).
Investigational
Matched Description: … Rineterkib is an inhibitor of extracellular signal-regulated kinase (ERK) being investigated in NCT04097821 ... (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel Ruxolitinib …
N-(2-Aminoethyl)-1-aziridineethanamine
First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS).
Experimental
1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine
1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine (PEPAP) is a synthetic analogue of meperidine. It is sold as a "synthetic heroin."
Experimental
Illicit
Matched Description: … 1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine (PEPAP) is a synthetic analogue of meperidine. …
Biricodar
The pipecolinate derivative biricodar (VX-710) is a clinically applicable modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1).
Investigational
Matched Description: … The pipecolinate derivative biricodar (VX-710) is a clinically applicable modulator of P-glycoprotein …
AT3022
AT3022, the Altea Therapeutics’s fentanyl citrate transdermal patch designed to provide safe and rapid management of moderate to severe chronic pain.
Investigational
Matched Description: … Altea Therapeutics’s fentanyl citrate transdermal patch designed to provide safe and rapid management of …
KB002
KB002 is an engineered human IgG1k antibody engineered human. It is developed for the treatment of autoimmune diseases, initially rheumatoid arthritis.
Investigational
Matched Description: … It is developed for the treatment of autoimmune diseases, initially rheumatoid arthritis. …
OSI-461
OSI-461 is a second-generation molecule belonging to a new class of drugs termed selective apoptotic anti-neoplastic drugs (SAANDs).
Investigational
Matched Description: … OSI-461 is a second-generation molecule belonging to a new class of drugs termed selective apoptotic …
Gallium maltolate
Gallium maltolate is Titan’s novel oral agent in development for the potential treatment of chronic bacterial infections, bone disease and cancer.
Investigational
Matched Description: … Gallium maltolate is Titan’s novel oral agent in development for the potential treatment of chronic bacterial …
Aplaviroc
A spiro-diketo-piperazine; a potent noncompetitive allosteric antagonist of the CCR5 receptor with concomitantly potent antiviral effects for HIV-1.
Investigational
Matched Description: … A spiro-diketo-piperazine; a potent noncompetitive allosteric antagonist of the CCR5 receptor with concomitantly …
Radgocitabine
2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment of Advanced Colorectal Cancer.
Investigational
Matched Description: … '-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment of …
AZD-1305
AZD1305 has been used in trials studying the treatment and basic science of Atrial Flutter, Atrial Fibrillation, and Left Ventricle Function.
Investigational
Matched Description: … AZD1305 has been used in trials studying the treatment and basic science of Atrial Flutter, Atrial Fibrillation …
Displaying drugs 6126 - 6150 of 8282 in total