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Displaying drugs 6176 - 6200 of 10948 in total
Edotreotide
Investigational
Matched Synonyms: … -((1r,2r)-2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic(2->7)-disulfide ... -((1r,2r)-2-hydroxy-1-(hydroxymethyl)propyl)-l-cysteinamide cyclic (2->7)-disulfide ... N-((4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacycoldodec-1-yl)acetyl-d-phenylalanyl-l-cysteinyl-l-tyrosyl-d-tryprophyl-l-lysyl-l-threonyl-n …
Matched Iupac: … }-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo ... 2-[4-({[(1R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(2R,3R)-1,3-dihydroxybutan-2-yl]carbamoyl ... (carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl]acetic acid ... -1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]carbamoyl}-2-phenylethyl]carbamoyl}methyl)-7,10-bis …
Matched Iupac: … }-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo ... 2-[4-({[(1R)-1-{[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(2R,3R)-1,3-dihydroxybutan-2-yl]carbamoyl ... (carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl]acetic acid ... -1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]carbamoyl}-2-phenylethyl]carbamoyl}methyl)-7,10-bis …
2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide
Experimental
Matched Name: … 2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide …
Matched Iupac: … 2-[(2-chloro-4-iodophenyl)amino]-N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluorobenzamide …
Matched Iupac: … 2-[(2-chloro-4-iodophenyl)amino]-N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluorobenzamide …
4,6-Dideoxy-4-{[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino}hexopyranose
Experimental
Matched Name: … 4,6-Dideoxy-4-{[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino}hexopyranose …
Matched Iupac: … (2R,3R,4S,5S,6R)-6-methyl-5-{[(1S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}oxane …
Matched Iupac: … (2R,3R,4S,5S,6R)-6-methyl-5-{[(1S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}oxane …
Zolbetuximab
Zolbetuximab is under investigation in clinical trial NCT01630083 (Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer).
Investigational
3,6,9,12,15-Pentaoxaheptadecane
Experimental
Elesclomol
Elesclomol is a novel, injectable, drug candidate that kills cancer cells by elevating oxidative stress levels beyond a breaking point, triggering programmed cell death. In preclinical models elesclomol showed potent killing of a broad range of cancer cell types at high doses, and an ability to strongly enhance the efficacy...
Investigational
Matched Synonyms: … 1-N'-Benzenecarbothioyl-3-(2-benzenecarbothioyl-2-methylhydrazinyl)-N'-methyl-oxopropanehydrazidide …
Matched Iupac: … N'1,N'3-dibenzenecarbothioyl-N'1,N'3-dimethylpropanedihydrazide …
Matched Iupac: … N'1,N'3-dibenzenecarbothioyl-N'1,N'3-dimethylpropanedihydrazide …
Flubrobenguane F18
Investigational
Matched Synonyms: … N-((3-bromo-4-(3-(fluoro-18f)propoxy)phenyl)methyl)guanidine …
Matched Iupac: … N-({3-bromo-4-[3-(¹⁸F)fluoropropoxy]phenyl}methyl)guanidine …
Matched Iupac: … N-({3-bromo-4-[3-(¹⁸F)fluoropropoxy]phenyl}methyl)guanidine …
Zebularine
A chemically stable, cytidine analog that displays anti-tumor properties. It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates. Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo.
Experimental
Matched Synonyms: … 1-beta-D-ribofuranosyl-2(1H)-pyrimidinone ... 1-beta-D-ribofuranosylpyrimidin-2(1H)-one ... Pyrimidin-2-one ribonucleoside …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
trans-2-hydroxycinnamic acid
Experimental
Matched Synonyms: … (2E)-3-(2-hydroxyphenyl)-2-propenoic acid ... (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid ... (E)-3-(2-Hydroxyphenyl)-2-propenoic acid …
Matched Name: … trans-2-hydroxycinnamic acid …
Matched Iupac: … (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid …
Matched Name: … trans-2-hydroxycinnamic acid …
Matched Iupac: … (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid …
Pipamperone
Pipamperone is a typical antipsychotic of the butyrophenone family used in the treatment of schizophrenia. It was developed by Janssen Pharmaceutica in 1961 and started its first round of clinical trials in 1963 [L1514, L1518].
In an effort to improve haloperidol's pharmacological effects, Janssen discovered that pipamperone, an agent whose...
Investigational
Matched Iupac: … 1'-[4-(4-fluorophenyl)-4-oxobutyl]-[1,4'-bipiperidine]-4'-carboxamide …
Matched Salts cas: … 2448-68-2 …
Matched Salts cas: … 2448-68-2 …
(2R)-1-(2,6-dimethylphenoxy)propan-2-amine
Experimental
Matched Name: … (2R)-1-(2,6-dimethylphenoxy)propan-2-amine …
Matched Iupac: … (2R)-1-(2,6-dimethylphenoxy)propan-2-amine …
Matched Iupac: … (2R)-1-(2,6-dimethylphenoxy)propan-2-amine …
Halofuginone
Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis in mice. Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S....
Investigational
Vet approved
Matched Synonyms: … (+/-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinone …
Matched Iupac: … 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}-3,4-dihydroquinazolin-4-one …
Matched Description: … (MMP-2) gene expression. ... weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}-3,4-dihydroquinazolin-4-one …
Matched Description: … (MMP-2) gene expression. ... weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE
Experimental
Matched Name: … N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE …
Matched Iupac: … benzyl N-[(1S)-1-{[(2S,3S)-3-hydroxy-1-(4-hydroxyphenyl)butan-2-yl]carbamoyl}-3-methylbutyl]carbamate …
Matched Iupac: … benzyl N-[(1S)-1-{[(2S,3S)-3-hydroxy-1-(4-hydroxyphenyl)butan-2-yl]carbamoyl}-3-methylbutyl]carbamate …
3,5-Diaminophthalhydrazide
Experimental
Bermekimab
Bermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis).
Investigational
(-)-beta-Elemene
Investigational
Matched Synonyms: … Cyclohexane, 1-ethenyl-1-methyl-2,4-bis(1-methylethenyl)-, (1s,2s,4r)- …
Matched Iupac: … (1S,2S,4R)-1-ethenyl-1-methyl-2,4-bis(prop-1-en-2-yl)cyclohexane …
Matched Iupac: … (1S,2S,4R)-1-ethenyl-1-methyl-2,4-bis(prop-1-en-2-yl)cyclohexane …
Indolepropionic acid
Experimental
Matched Synonyms: … 3-(3-Indole)propionic acid ... 3-(3-Indolyl)propanoic acid ... 3-(3-Indolyl)propionic acid …
Matched Iupac: … 3-(1H-indol-3-yl)propanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 3-(1H-indol-3-yl)propanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
GBR-12783
A selective inhibitor of dopamine uptake.
Investigational
Matched Iupac: … 1-[2-(diphenylmethoxy)ethyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
beta-2-Thienyl-L-alanine
Experimental
Matched Synonyms: … L-3-(2-thienyl)alanine ... beta-(2-Thienyl)-L-alanine …
Matched Name: … beta-2-Thienyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-(thiophen-2-yl)propanoic acid …
Matched Name: … beta-2-Thienyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-(thiophen-2-yl)propanoic acid …
Indatraline
Indatraline is a nonselective monoamine reuptake inhibitor.
Investigational
Matched Synonyms: … (+/-)-trans-3-(3,4-dichlorophenyl)-n-methyl-1-indanamine …
Matched Iupac: … (1R,3S)-3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine …
Matched Iupac: … (1R,3S)-3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine …
gamma-carboxy-L-glutamic acid
Experimental
Matched Synonyms: … (3S)-3-amino-1,1,3-propanetricarboxylic acid …
Matched Iupac: … (1S)-1-aminopropane-1,3,3-tricarboxylic acid …
Matched Categories: … 1-Carboxyglutamic Acid …
Matched Iupac: … (1S)-1-aminopropane-1,3,3-tricarboxylic acid …
Matched Categories: … 1-Carboxyglutamic Acid …
2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
Experimental
Matched Name: … 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol …
Matched Iupac: … (2R,3R,4S,5R,6R)-2-(hexyloxy)-6-(hydroxymethyl)oxane-3,4,5-triol …
Matched Iupac: … (2R,3R,4S,5R,6R)-2-(hexyloxy)-6-(hydroxymethyl)oxane-3,4,5-triol …
(2R)-2-ETHYL-1-HEXANESULFONIC ACID
Experimental
Matched Name: … (2R)-2-ETHYL-1-HEXANESULFONIC ACID …
Matched Iupac: … {[(2R)-2-ethylhexyl]oxy}sulfonic acid …
Matched Iupac: … {[(2R)-2-ethylhexyl]oxy}sulfonic acid …
3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE
Experimental
Matched Name: … 3-[(3-(2-CARBOXYETHYL)-4-METHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE …
Matched Iupac: … 3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid …
Matched Iupac: … 3-(4-methyl-2-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid …
Poliomyelitis virus type 3 (live, attenuated)
Experimental
Matched Synonyms: … Poliomyelitis virus type 3, Leon - 12a1b strain …
Matched Name: … Poliomyelitis virus type 3 (live, attenuated) …
Matched Mixtures name: … ไบวาเลนท์ โอรัล โปลิโอ วัคซีน ทัยป์ 1 และ 3 ... วัคซีนป้องกันโปลิโอสองสายพันธุ์ (สายพันธุ์ 1 และ 3) ชนิดรับประทาน ... วัคซีนป้องกันโปลิโอสองสายพันธุ์ (สายพันธุ์ 1 และ 3)ชนิดรับประทาน …
Matched Name: … Poliomyelitis virus type 3 (live, attenuated) …
Matched Mixtures name: … ไบวาเลนท์ โอรัล โปลิโอ วัคซีน ทัยป์ 1 และ 3 ... วัคซีนป้องกันโปลิโอสองสายพันธุ์ (สายพันธุ์ 1 และ 3) ชนิดรับประทาน ... วัคซีนป้องกันโปลิโอสองสายพันธุ์ (สายพันธุ์ 1 และ 3)ชนิดรับประทาน …
Displaying drugs 6176 - 6200 of 10948 in total