Displaying drugs 601 - 625 of 981 in total
Clozapine
Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. Clozapine displays affinity to various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and deeming it "atypical". . This low affinity to dopamine receptors results in fewer extrapyramidal side effects,...
Approved
Matched Description: … side effects, notably gastrointestinal hypomotility and orthostatic hypotension. ... [A185747] However, its promiscuity toward the muscarinic and adrenergic receptors can result in other ... particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … CLOZAPIN BETA 25MG ... CLOZAPIN BETA 50MG ... CLOZAPIN BETA 100MG …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … CLOZAPIN BETA 25MG ... CLOZAPIN BETA 50MG ... CLOZAPIN BETA 100MG …
Baclofen
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … beta-(4-Chlorophenyl)gaba ... beta-(Aminomethyl)-p-chlorohydrocinnamic acid ... beta-(p-Chlorophenyl)-gamma-aminobutyric acid …
Matched Description: … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Agomelatine
Agomelatine is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines Agency (EMA) in 2005. The Committee...
Approved
Investigational
Matched Description: … Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors ... Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines …
Matched Products: … AGOMELATIN BETA 25MG FTA …
Matched Products: … AGOMELATIN BETA 25MG FTA …
Arbutin
Extracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal dietary supplements . Most commonly, it is an active ingredient in skincare and cosmetic products...
Approved
Matched Synonyms: … beta-Arbutin ... 4-Hydroxyphenyl-beta-D-glucopyranoside ... Hydroquinone-O-beta-D-glucopyranoside …
Matched Description: … in the _Ericaceae_ family, arbutin is a beta-D-glucopyranoside of [DB09526]. ... and [DB09526] [F43]. ... It is found in foods, over-the-counter drugs, and herbal dietary supplements [F43]. …
Matched Description: … in the _Ericaceae_ family, arbutin is a beta-D-glucopyranoside of [DB09526]. ... and [DB09526] [F43]. ... It is found in foods, over-the-counter drugs, and herbal dietary supplements [F43]. …
N-beta-D-glucopyranosylacetamide
Experimental
Matched Synonyms: … 1-N-acetyl-beta-D-glucosamine …
Matched Name: … N-beta-D-glucopyranosylacetamide …
Matched Name: … N-beta-D-glucopyranosylacetamide …
Methyl beta-L-fucopyranoside
Experimental
Matched Synonyms: … Methyl 6-deoxy-beta-L-galactopyranoside …
Matched Name: … Methyl beta-L-fucopyranoside …
Matched Name: … Methyl beta-L-fucopyranoside …
Glycyrrhizic acid
Glycyrrhizic acid is extracted from the root of the licorice plant; Glycyrrhiza glabra. It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and biological activities. When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium glycyrrhizin. Glycyrrhizic...
Approved
Experimental
Matched Synonyms: … 18-beta-Glycyrrhizic acid …
Matched Description: … Glycyrrhizic acid is extracted from the root of the licorice plant; _Glycyrrhiza glabra_. ... It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and ... When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism …
Matched Description: … Glycyrrhizic acid is extracted from the root of the licorice plant; _Glycyrrhiza glabra_. ... It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and ... When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism …
Lactulose
Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic encephalopathy (PSE).[FDA Label,L6199,L6202] Despite being first synthesized in 1929 , investigations regarding its possible use as a laxative for...
Approved
Matched Synonyms: … 4-O-beta-D-Galactopyranosyl-D-fructose ... 4-O-beta-D-Galactopyranosyl-D-fructofuranose …
Matched Description: … possible use as a laxative for the treatment of chronic constipation did not occur until the 1960s and ... [L6202] Nevertheless, although lactulose received formal FDA approval in 1977 and has since become ... List of Essential Medicines as one of the most effective and safe medicines employed in a health system …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Description: … possible use as a laxative for the treatment of chronic constipation did not occur until the 1960s and ... [L6202] Nevertheless, although lactulose received formal FDA approval in 1977 and has since become ... List of Essential Medicines as one of the most effective and safe medicines employed in a health system …
Matched Categories: … Alimentary Tract and Metabolism …
Willardiine
Willardiine is a compound isolated from seeds of Acacia willariana.
Experimental
Matched Synonyms: … beta-(2,4-Dihydroxypyrimidin-1-yl)alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cryptoxanthin
Experimental
Matched Synonyms: … beta-Cryptoxanthin …
Matched Categories: … Diet, Food, and Nutrition …
Matched Categories: … Diet, Food, and Nutrition …
Nisevokitug
Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients).
Investigational
Matched Synonyms: … Anti-tgf-beta monoclonal antibody nis793 …
Matched Description: … in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy ... Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety and Efficacy ... Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
beta-D-glucuronic acid
Experimental
Matched Synonyms: … beta-D-Glucopyranuronic acid …
Matched Name: … beta-D-glucuronic acid …
Matched Name: … beta-D-glucuronic acid …
Cytarabine
A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale,...
Approved
Investigational
Matched Synonyms: … 1-beta-D-Arabinofuranosylcytosine ... Cytosine-1-beta-D-arabinofuranoside ... 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone …
Matched Description: … It also has antiviral and immunosuppressant properties. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... cytarabine and daunorubicin ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … It also has antiviral and immunosuppressant properties. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... cytarabine and daunorubicin ... Nucleic Acids, Nucleotides, and Nucleosides …
beta-D-glucose 6-phosphate
Experimental
Matched Synonyms: … beta-D-glucose-6-phosphate ... beta-D-Glucose 6-phosphic acid ... beta-D-glucose 6-(dihydrogen phosphate) …
Matched Name: … beta-D-glucose 6-phosphate …
Matched Name: … beta-D-glucose 6-phosphate …
Amdoxovir
Investigational
Matched Synonyms: … beta-D-2,6-Diaminopurine-dioxolane …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Disitertide
Disitertide has been used in trials studying the treatment of Skin Fibrosis.
Investigational
Matched Synonyms: … Peptide 144 TGF beta-1 inhibitor …
2'-fluoro-5-ethylarabinosyluracil
2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and Recurrent Mantle Cell Lymphoma, among others.
Investigational
Matched Synonyms: … 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil ... 2'-Fluoro-5-ethyl-1-beta-D-arabinofuranosyluracil …
Matched Description: … Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Bronopol
Bronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an organic compound with wide-spectrum antimicrobial properties. First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives . Bronopol is used as a microbicide or microbiostat...
Approved
Matched Synonyms: … beta-Bromo-beta-nitrotrimethyleneglycol …
Matched Description: … First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was ... registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives ... Bronopol is used as a microbicide or microbiostat in various commercial and industrial applications, …
Matched Categories: … Indicators and Reagents …
Matched Description: … First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was ... registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives ... Bronopol is used as a microbicide or microbiostat in various commercial and industrial applications, …
Matched Categories: … Indicators and Reagents …
1,4-dithio-beta-D-glucopyranose
Experimental
Matched Synonyms: … 1,4-deoxy-1,4-dithio-beta-D-glucopyranose …
Matched Name: … 1,4-dithio-beta-D-glucopyranose …
Matched Name: … 1,4-dithio-beta-D-glucopyranose …
N-(Benzoylcarbamoyl)-beta-D-glucopyranosylamine
Experimental
Matched Synonyms: … N-benzoyl-N'-beta-D-glucopyranosyl urea …
Matched Name: … N-(Benzoylcarbamoyl)-beta-D-glucopyranosylamine …
Matched Name: … N-(Benzoylcarbamoyl)-beta-D-glucopyranosylamine …
Epicriptine
Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro-13'-epi-b-ergocryptine. Together with the alpha-dihydroergocryptine, it represents one-third of the ergoloid mesylate mixture. Epicriptine differs from the alpha form on the position of one methyl group. To know more about the mixture please visit DB01049
Approved
Matched Synonyms: … dihydro-beta-ergocryptine …
Matched Description: … Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro …
Matched Description: … Epicriptine is also known as beta-dihydroergocryptine presents a molecular formula of 9,10 alpha-dihydro …
AVID-200
AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.
Investigational
Matched Synonyms: … Tgf-beta 1/3 inhibitor avid200 ... Tgf-.beta. ligand trap comprised of tgf-.beta. receptor ectodomains fused to a human fc domain (avid- …
Matched Description: … AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein. …
Matched Description: … AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein. …
Displaying drugs 601 - 625 of 981 in total