Displaying drugs 601 - 625 of 719 in total
Ibuprofen
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched Description: … [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development ... in the UK in 1969 and USA in 1974. ... the first of the propionics. …
Matched Mixtures name: … Care One Ibuprofen Cold and Sinus ... Meds on the Go ... Care One Ibuprofen PM …
Matched Categories: … Ibuprofen and isomer ... codeine and ibuprofen ... oxycodone and ibuprofen ... hydrocodone and ibuprofen ... Antiinflammatory and Antirheumatic Products …
Matched Products: … Care One ibuprofen ... Care One Ibuprofen ... Care One Ibuprofen Ib …
Matched Mixtures name: … Care One Ibuprofen Cold and Sinus ... Meds on the Go ... Care One Ibuprofen PM …
Matched Categories: … Ibuprofen and isomer ... codeine and ibuprofen ... oxycodone and ibuprofen ... hydrocodone and ibuprofen ... Antiinflammatory and Antirheumatic Products …
Matched Products: … Care One ibuprofen ... Care One Ibuprofen ... Care One Ibuprofen Ib …
Ceftazidime
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Iupac: … -5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium ... -7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-carboxylato-8-oxo …
Matched Description: … essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately bacterial ... [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone ... a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and …
Matched Products: … Ceftazidime and Dextrose ... CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL …
Matched Description: … essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and ultimately bacterial ... [L32935] Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone ... a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and …
Matched Products: … Ceftazidime and Dextrose ... CEFTAZIDIME ALVOGEN POWDER FOR SOLUTION FOR INJECTION AND INFUSION 1G/ VIAL …
Fimaporfin
Investigational
Matched Synonyms: … , mixture of three isomers a, b and c (25%, 50%, 25%) ... Benzenesulfonic acid, 4,4'-(7,8(or 17,18)-dihydro-10,15(or 15,20)-diphenyl-21h,23h-porphine-5,20(or 5,10 ... 4,4'-(15,20-diphenyl-7,8(or 12,13 or 17,18)-dihydro-21h,23h-porphine-5,10-diyl)bisbenzenesulfonic acid …
Mozafancogene autotemcel
RP-L102 is a lentiviral vector carrying the Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of Fanconi anemia type A
Investigational
Matched Synonyms: … Autologous CD34+-enriched Hematopoietic Stem and Progenitor Cells Transduced with Lentiviral Vector Carrying …
Matched Description: … Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of …
Matched Description: … Fanconi Anemia-A (FANCA) gene currently being developed by Rocket Pharmaceuticals for the treatment of …
CP-12
Investigational
Matched Synonyms: … CYCLIZED P12 (PEPTIDE BOND BETWEEN THE CARBOXY AND AMINO-TERMINAL ENDS OF THE LINEAR PEPTIDE PSHISKYILRWRPK …
Pacmilimab
Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer).
Investigational
Matched Synonyms: … HUMAN MONOCLONAL CX-072 .GAMMA.4-CHAIN), DISULFIDE WITH PRODOMAIN PROTEIN (SYNTHETIC MASKING MOIETY AND …
Matched Description: … Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer). ... Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor …
Matched Description: … Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer). ... Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor …
Prizloncabtagene autoleucel
C-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR.
Investigational
Matched Synonyms: … , non-replicating lentiviral vector, encoding a bispecific chimeric antigen receptor targeting CD19 and …
Ketamine
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor...
Approved
Vet approved
Matched Synonyms: … 2-(o-chlorophenyl)-2-(methylamino)-cyclohexanone …
Matched Iupac: … 2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one …
Matched Description: … It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients ... it produced minor hallucinogenic effects and shorter psychotomimetic effects. ... It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … 2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one …
Matched Description: … It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients ... it produced minor hallucinogenic effects and shorter psychotomimetic effects. ... It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, …
Matched Categories: … Amino Acids, Peptides, and Proteins …
2'-O-Methyl-3'-Methyl-3'-Deoxy-Arabinofuranosyl-Thymine-5'-Phosphate
Experimental
Matched Name: … 2'-O-Methyl-3'-Methyl-3'-Deoxy-Arabinofuranosyl-Thymine-5'-Phosphate …
Factor IX Complex (Human)
Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often include Factor IX (antihemophilic factor B), Factor II (prothrombin), Factor X (Stuart-Prower Factor), and low levels of...
Approved
Investigational
Matched Synonyms: … Coagulation factor IX, II, VII and X in combination …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting ... requiring rapid reversal of therapy. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Description: … Coagulation factors are purified from pooled human plasma and subsequently sterilized and treated. ... Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting ... requiring rapid reversal of therapy. …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Atidarsagene autotemcel
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC …
Matched Description: … authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic ... Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic ... Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Nogapendekin alfa
Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Fusion protein consisting of il-15n72d and il-15rasu/fc …
Matched Description: … stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which also ... commonly treated with transurethral resection of the bladder tumour and Bacillus Calmette-Guérin (BCG ... It is one of the active ingredients in Anktiva, a combination product also containing [inbakicept], where …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which also ... commonly treated with transurethral resection of the bladder tumour and Bacillus Calmette-Guérin (BCG ... It is one of the active ingredients in Anktiva, a combination product also containing [inbakicept], where …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mucor circinelloides f. circinelloides
Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides …
Chrysoeriol
Investigational
Matched Synonyms: … 3'-o-methylluteolin ... 4h-1-benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)- …
Matched Iupac: … 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one …
Matched Iupac: … 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one …
1-Deoxy-6-O-Phosphono-1-[(Phosphonomethyl)Amino]-L-Threo-Hexitol
Experimental
Matched Name: … 1-Deoxy-6-O-Phosphono-1-[(Phosphonomethyl)Amino]-L-Threo-Hexitol …
Matched Iupac: … {[(2R,3R,4R,5R)-2,3,4,5-tetrahydroxy-6-[(phosphonomethyl)amino]hexyl]oxy}phosphonic acid …
Matched Iupac: … {[(2R,3R,4R,5R)-2,3,4,5-tetrahydroxy-6-[(phosphonomethyl)amino]hexyl]oxy}phosphonic acid …
Gimatecan
Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
Investigational
Matched Synonyms: … -3,14-dioxo-3,4,12,14-tetrahydro-1-H-pyrano[3',4':6,7]-indolizino-[1,2-b]-quinoline-11-carbaldehyde O- ... indolizino[1,2-b]quinoline-11-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-, 11-[O- …
Matched Iupac: … (19S)-10-[(1E)-[(tert-butoxy)imino]methyl]-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰ …
Matched Iupac: … (19S)-10-[(1E)-[(tert-butoxy)imino]methyl]-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰ …
Ivermectin
Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Iupac: … [15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen-2'-one ... 24'S)-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy ... -2,6'-tetracyclo[15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen-2'-one; (1'R,2R,4'S,5S ... }-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-6-(propan-2-yl)-3',7',19'-trioxaspiro[oxane ... 2-yl]-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy …
Matched Description: … use for the prophylaxis and treatment of COVID-19. ... with statistical errors and accusations of plagiarism. ... _in vitro_ data, and the clinical utility of this data remains unclear. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Scabicides and Pediculicides ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep ... I-Dectin 0.5 % Pour-On ... Vimectin 0.5% w/v Pour On …
Matched Description: … use for the prophylaxis and treatment of COVID-19. ... with statistical errors and accusations of plagiarism. ... _in vitro_ data, and the clinical utility of this data remains unclear. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Scabicides and Pediculicides ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep ... I-Dectin 0.5 % Pour-On ... Vimectin 0.5% w/v Pour On …
Aceclofenac
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Synonyms: … glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate ester …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid …
Matched Description: … , crepitus, and local inflammation [A19666]. ... modification in effort to improve the gastrointestinal tolerability of the drug. ... It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid …
Matched Description: … , crepitus, and local inflammation [A19666]. ... modification in effort to improve the gastrointestinal tolerability of the drug. ... It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
5-methoxy-N,N-dimethyltryptamine
5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug, as well as dimethyltryptamine and bufotenin, have been registered to be used in South America in religious and spiritual rituals.
Experimental
Illicit
Matched Synonyms: … O-methylbufotenine …
Matched Description: … It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado ... America in religious and spiritual rituals. ... This drug, as well as [dimethyltryptamine] and [bufotenin], have been registered to be used in South …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Description: … It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado ... America in religious and spiritual rituals. ... This drug, as well as [dimethyltryptamine] and [bufotenin], have been registered to be used in South …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Zorevunersen
Investigational
Matched Synonyms: … Rna, (p-thio)(2'-o-(2-methoxyethyl))(a-g-m5u-m5u-g-g-a-g-m5c-a-a-g-a-m5u-m5u-a-m5u-m5c) …
Dextromethorphan
Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse. Although similar in structure to other opioids, it has minimal interaction with opioid receptors. Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Approved
Matched Description: … and also a drug of abuse. ... Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant …
Matched Mixtures name: … Cold and Flu All In One ... Meds on the Go ... Cold and Flu-IN-one Extra Strength …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... bupropion and dextromethorphan ... Heterocyclic Compounds with 4 or More Rings ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake …
Matched Products: … Up and Up Cough Suppressant DM ... Up and Up 12 Hour Cough Relief ... Foster and Thrive 12 Hour Cough Relief …
Matched Mixtures name: … Cold and Flu All In One ... Meds on the Go ... Cold and Flu-IN-one Extra Strength …
Matched Categories: … Cough and Cold Preparations ... Opium Alkaloids and Derivatives ... bupropion and dextromethorphan ... Heterocyclic Compounds with 4 or More Rings ... Combined Inhibitors of Serotonin/Norepinephrine Reuptake …
Matched Products: … Up and Up Cough Suppressant DM ... Up and Up 12 Hour Cough Relief ... Foster and Thrive 12 Hour Cough Relief …
N,N-[2,5-O-Dibenzyl-glucaryl]-DI-[1-amino-indan-2-OL]
Experimental
Matched Name: … N,N-[2,5-O-Dibenzyl-glucaryl]-DI-[1-amino-indan-2-OL] …
4-[(3-BROMO-4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE
Experimental
Matched Name: … 4-[(3-BROMO-4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE …
Caffeine
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Description: … conditions of the premature newborn, pain relief, and to combat drowsiness. ... development and may eventually cause asthma or early onset emphysema in those born prematurely. ... [T716] Caffeine is also used in a variety of cosmetic products and can be administered topically, orally …
Matched Mixtures name: … EMOL OSK ... Midol One ... OKA GALEZ …
Matched Categories: … combinations of xanthines ... caffeine and sodium benzoate ... Respiratory and CNS Stimulants ... Caffeine and Caffeine Containing Products ... Anorexigenic Agents & Respiratory and CNS Stimulants …
Matched Products: … Caffeine and Sodium Benzoate …
Matched Mixtures name: … EMOL OSK ... Midol One ... OKA GALEZ …
Matched Categories: … combinations of xanthines ... caffeine and sodium benzoate ... Respiratory and CNS Stimulants ... Caffeine and Caffeine Containing Products ... Anorexigenic Agents & Respiratory and CNS Stimulants …
Matched Products: … Caffeine and Sodium Benzoate …
Omeprazole
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Description: … characterized by the oversecretion of gastric acid. ... of many other proton pump inhibitor drugs [A174232]. ... Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults …
Matched Mixtures name: … Zegerid OTC ... Zegerid OTC ... Zegerid OTC …
Matched Categories: … Alimentary Tract and Metabolism ... Omeprazole and enantiomer ... omeprazole, amoxicillin and rifabutin ... omeprazole, amoxicillin and metronidazole ... omeprazole, amoxicillin and clarithromycin …
Matched Products: … Up and Up Omeprazole ... Berkley and Jensen Omeprazole ... Foster and Thrive Omeprazole …
Matched Mixtures name: … Zegerid OTC ... Zegerid OTC ... Zegerid OTC …
Matched Categories: … Alimentary Tract and Metabolism ... Omeprazole and enantiomer ... omeprazole, amoxicillin and rifabutin ... omeprazole, amoxicillin and metronidazole ... omeprazole, amoxicillin and clarithromycin …
Matched Products: … Up and Up Omeprazole ... Berkley and Jensen Omeprazole ... Foster and Thrive Omeprazole …
Displaying drugs 601 - 625 of 719 in total