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Displaying drugs 6226 - 6250 of 7657 in total

2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide

Experimental
Matched Name: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1S)-1-(hydroxymethyl)propyl]acetamide …
Matched Iupac: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-[(2S)-1-hydroxybutan-2-yl]ethanimidic acid …

Rhein

Rhein is an anthraquinone metabolite of rheinanthrone and senna glycoside is present in many medicinal plants including Rheum palmatum, Cassia tora, Polygonum multiflorum, and Aloe barbadensis . It is known to have hepatoprotective, nephroprotective, anti-cancer, anti-inflammatory, and several other protective effects.
Experimental

DSM-265

DSM265 has been used in trials studying the prevention and treatment of Malaria.
Investigational
Matched Synonyms: … 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin ... 2-(1,1-Difluoroethyl)-5-methyl-N-[4-(pentafluoro-λ6-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7 ... Sulfur, (4-((2-(1,1-difluoroethyl)-5-methyl(1,2,4)triazolo(1,5-a)pyrimidin-7-yl)amino)phenyl)pentafluoro …
Matched Iupac: … 2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-lambda6-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin …

4-(Hydrogen sulfate)-beta-D-galactopyranose

Experimental
Matched Synonyms: … 4-O-Sulfo-β-D-galactopyranose ... 4-(Hydrogen sulfate)-beta-D-galactopyranose …
Matched Name: … 4-(Hydrogen sulfate)-beta-D-galactopyranose …
Matched Iupac: … [(2R,3R,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxidanesulfonic acid …

(S)-4-hydroxymandelonitrile

Experimental
Matched Synonyms: … 4-Hydroxy-L-mandelonitrile ... (2S)-Hydroxy(4-hydroxyphenyl)ethanenitrile …
Matched Name: … (S)-4-hydroxymandelonitrile …
Matched Iupac: … (2S)-2-hydroxy-2-(4-hydroxyphenyl)acetonitrile …

DSP107

DSP107 is a bi-functional, trimeric, fusion protein composed of sequences from the extracellular domain of SIRPα and 4-1BBL.
Investigational
Matched Synonyms: … SIRPα -4-1BBL …
Matched Description: … bi-functional, trimeric, fusion protein composed of sequences from the extracellular domain of SIRPα and 4- …

Iodopropynyl butylcarbamate

Experimental
Matched Synonyms: … 3-iodo-2-propynyl butylcarbamate ... 3-iodoprop-2-ynyl butylcarbamate ... 3-iodo-2-propyn-1-yl N-butylcarbamate …
Matched Iupac: … 3-iodoprop-2-yn-1-yl N-butylcarbamate …

Nurulimab

Nurulimab is under investigation in clinical trial NCT05732805 (A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-pd-1 Compared to Anti-pd-1 Monotherapy as First-line Treatment in Subjects With Unresectable/metastatic Melanoma).
Investigational

Spanlecortemlocel

Investigational

Zeluvalimab

Zeluvalimab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational

Diphthamide

Experimental
Matched Synonyms: … 2-(3-Carboxyamido-3-(Trimethylammonio)Propyl)Histidine …
Matched Iupac: … [(1S)-3-{4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-2-yl}-1-carbamoylpropyl]trimethylazanium …

Urolithin A

Urolithin A is a metabolite of ellagic acid. It has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging.
Investigational

(1n)-4-N-Butoxyphenylsulfonyl-(2r)-N-Hydroxycarboxamido-(4s)-Methanesulfonylamino-Pyrrolidine

Experimental
Matched Name: … (1n)-4-N-Butoxyphenylsulfonyl-(2r)-N-Hydroxycarboxamido-(4s)-Methanesulfonylamino-Pyrrolidine …
Matched Iupac: … (2R,4S)-1-(4-butoxybenzenesulfonyl)-N-hydroxy-4-methanesulfonamidopyrrolidine-2-carboxamide …

3-(Benzoylamino)-L-Alanine

Experimental
Matched Name: … 3-(Benzoylamino)-L-Alanine …
Matched Iupac: … (2S)-2-amino-3-(phenylformamido)propanoic acid …

3-Oxo-Pentadecanoic Acid

Experimental
Matched Name: … 3-Oxo-Pentadecanoic Acid …
Matched Iupac: … 3-oxopentadecanoic acid …

Rugonersen

Rugonersen is a locked nucleic acid antisense oligonucleotide under investigation for the treatment of Angelman Syndrome.
Investigational

{[(2,2-Dihydroxy-Ethyl)-(2,3,4,5-Tetrahydroxy-6-Phosphonooxy-Hexyl)-Amino]-Methyl}-Phosphonic Acid

Experimental

[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine

Experimental
Matched Name: … [2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine …
Matched Iupac: … 3-[(2S)-3-[4-(3-aminopropanoyl)piperazin-1-yl]-3-oxo-2-[2,4,6-tris(propan-2-yl)benzenesulfonamido]propyl …

(2R)-2-{(1R)-2-oxo-1-[(2-thienylacetyl)amino]ethyl}-5,6-dihydro-2h-1,3-thiazine-4-carboxylic acid

Experimental
Matched Name: … (2R)-2-{(1R)-2-oxo-1-[(2-thienylacetyl)amino]ethyl}-5,6-dihydro-2h-1,3-thiazine-4-carboxylic acid …
Matched Iupac: … (2R)-2-[(1R)-2-oxo-1-[2-(thiophen-2-yl)acetamido]ethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid …

2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide

Experimental
Matched Name: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-n-[(1R)-1-(hydroxymethyl)propyl]acetamide …
Matched Iupac: … 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-[(2R)-1-hydroxybutan-2-yl]acetamide …

3-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE

Experimental
Matched Name: … 3-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE …
Matched Iupac: … 3-({4-[(6-chloro-1-benzothiophen-2-yl)sulfonyl]-2-oxopiperazin-1-yl}methyl)benzene-1-carboximidamide …

Fitusiran

Fitusiran is under investigation in clinical trial NCT02554773 (An Open-label Extension Study of an Investigational Drug, ALN-AT3SC, in Patients With Moderate or Severe Hemophilia A or B).
Investigational

Arbaclofen Placarbil

Arbaclofen Placerbil is a prodrug of Arbaclofen, which is a selective gamma-amino-butyric acid type B receptor agonist and the R-enantiomer of baclofen. It was discovered, and has been patented by XenoPort as a new chemical entity with an improved pharmacokinetic profile compared to baclofen, which allows for sustained release properties....
Investigational
Matched Iupac: … (3R)-3-(4-chlorophenyl)-4-({[(1S)-2-methyl-1-[(2-methylpropanoyl)oxy]propoxy]carbonyl}amino)butanoic …

[(2R)-1-[(2S)-2-[[(2S,3S)-1-Chloro-6-(diaminomethylideneamino)-2-hydroxyhexan-3-yl]carbamoyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]azanium

Experimental
Matched Name: … -1-yl]-1-oxo-3-phenylpropan-2-yl]azanium ... [(2R)-1-[(2S)-2-[[(2S,3S)-1-Chloro-6-(diaminomethylideneamino)-2-hydroxyhexan-3-yl]carbamoyl]pyrrolidin …
Matched Iupac: … -1-yl]-1-oxo-3-phenylpropan-2-aminium ... (2R)-1-[(2S)-2-{[(2S,3S)-1-chloro-6-[(diaminomethylidene)amino]-2-hydroxyhexan-3-yl]carbamoyl}pyrrolidin …

BIIB015

BIIB015 is a humanized, IgG1 [immunoglobulin G 1], DM4-Conjugated, anti-cripto, monoclonal antibody. It has been investigated for the treatment of subjects with relapsed or refractory solid tumours.
Investigational
Displaying drugs 6226 - 6250 of 7657 in total