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Displaying drugs 6276 - 6300 of 12300 in total

{4-[(2R)-pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen-3-ylphenyl)methanone

Experimental
Matched Name: … {4-[(2R)-pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen-3-ylphenyl)methanone …
Matched Iupac: … (2R)-2-({4-[4-(thiophen-3-yl)benzoyl]phenoxy}methyl)pyrrolidine …

(2Z)-2-(Benzoylamino)-3-[4-(2-bromophenoxy)phenyl]acrylic acid

Experimental
Matched Synonyms: … (2Z)-2-(benzoylamino)-3-[4-(2-bromophenoxy)phenyl]-2-propenoic acid …
Matched Name: … (2Z)-2-(Benzoylamino)-3-[4-(2-bromophenoxy)phenyl]acrylic acid …
Matched Iupac: … (2Z)-3-[4-(2-bromophenoxy)phenyl]-2-(phenylformamido)prop-2-enoic acid …

FF-10501-01

FF-10501-01 is a novel, selective inosine monophosphate dehydrogenase (IMPDH) inhibitor with anticancer activity. FF-10501-01 is under investigation in clinical trial NCT03486353 (A Study of FF-10501-01 in Combination With Azacitidine in Patients With Myelodysplastic Syndrome).
Investigational

Uzansertib

Uzansertib is under investigation in clinical trial NCT02587598 (Study of INCB053914 in Subjects With Advanced Malignancies).
Investigational

Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1-Yl-Methanone

Experimental
Matched Name: … Cis-[4,5-Bis-(4-Chlorophenyl)-2-(2-Isopropoxy-4-Methoxyphenyl)-4,5-Dihyd Roimidazol-1-Yl]-Piperazin-1 …
Matched Iupac: … 1-[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazole-1- …

2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide

Experimental
Matched Name: … 2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide …
Matched Iupac: … 1-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}phenyl)-3-[2-(4-fluorophenyl)acetyl]urea …

SARS-CoV-2 Sclamp

The University of Queensland (UQ), in partnership with The Coalition for Epidemic Preparedeness Inovations (CEPI) and CSL has developed a COVID-19 candidate, SARS-CoV-2 Sclamp. The vaccine was developed using UQ’s rapid response ‘molecular clamp’ vaccine platform that locks surface proteins in a configuration that allows more robust immune responses, in...
Investigational
Matched Synonyms: … UQ-1-SARS-CoV-2-Sclamp ... SARS-CoV-2 Sclamp adjuvanted vaccine …
Matched Name: … SARS-CoV-2 Sclamp …
Matched Description: … The SARS-CoV-2 Sclamp Vaccine was developed within 3 weeks and moved immediately into preclinical testing ... Coalition for Epidemic Preparedeness Inovations (CEPI) and CSL has developed a COVID-19 candidate, SARS-CoV-2 …

(S)-alpha-methyl-4-carboxyphenylglycine

Experimental
Matched Synonyms: … (S)-(+)-α-amino-4-carboxy-2-methylbenzeneacetic ... (S)-a-methyl-4-carboxyphenylglycine ... (S)-α-methyl-4-carboxyphenylglycine …
Matched Name: … (S)-alpha-methyl-4-carboxyphenylglycine …
Matched Iupac: … 4-[(1S)-1-amino-1-carboxyethyl]benzoic acid …

Fluasterone

Has antiproliferative effects on HIV-1 and reduces HIV-1 replication.
Investigational
Matched Iupac: … (1S,2R,10R,11S,13R,15S)-13-fluoro-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-14-one …

Lumicitabine

Lumicitabine is under investigation in clinical trial NCT03010059 (A Study to Assess the Relative Bioavailability of JNJ64041575 Administered as 2 Different New Concept Formulations (Oral Suspension and Tablet) Compared to Their Respective Current Formulations, and to Assess the Effect of Food on the Pharmacokinetics of the 2 New Concept Formulations).
Investigational
Matched Iupac: … [(2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-2-(chloromethyl)-4-fluoro-3-[(2-methylpropanoyl ... )oxy]oxolan-2-yl]methyl 2-methylpropanoate …
Matched Description: … clinical trial NCT03010059 (A Study to Assess the Relative Bioavailability of JNJ64041575 Administered as 2 ... Their Respective Current Formulations, and to Assess the Effect of Food on the Pharmacokinetics of the 2 …

Levomethadone

Experimental
Matched Iupac: … (6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one …
Matched Products: … L-Polamidon 5 mg Tabletten ... Levo-Methasan 5 mg-Tabletten ... Lefisyo 5 mg/ml Lösung zum Einnehmen …

3-[(4-CHLOROANILINO)SULFONYL]THIOPHENE-2-CARBOXYLIC ACID

Experimental
Matched Name: … 3-[(4-CHLOROANILINO)SULFONYL]THIOPHENE-2-CARBOXYLIC ACID …
Matched Iupac: … 3-[(4-chlorophenyl)sulfamoyl]thiophene-2-carboxylic acid …

Sulbactam pivoxil

Experimental
Matched Iupac: … [(2S,5R)-3,3-dimethyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carbonyloxy]methyl 2,2- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRIAZA-CYCLOOCTADECOSINE-9-CARBONITRILE

Experimental
Matched Iupac: … (5R)-30-oxo-19-oxa-2,6,10,12-tetraazahexacyclo[18.6.2.1^{2,5}.1^{14,18}.0^{8,12}.0^{23,27}]triaconta- …

Blarcamesine

Investigational
Matched Synonyms: … Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanemethanamine ... Anavex 2-73 ... ANAVEX 2-73 FREE BASE …
Matched Iupac: … [(2,2-diphenyloxolan-3-yl)methyl]dimethylamine …
Matched Salts cas: … 195615-84-0 …

Butamirate

Experimental
Matched Iupac: … 2-[2-(diethylamino)ethoxy]ethyl 2-phenylbutanoate …
Matched Products: … TUSAMOL 7,5 MG/5 ML SURUP ... CODACTIV 7,5 MG/5 ML SURUP, 100 ML ... TAMIRAL 7,5 MG / 5 ML SURUP 100 ML …

ALS-08

ALS-08 is a proprietary creatine-derivative that is being developed as a potential therapeutic for amyotrophic lateral sclerosis (ALS). It is being developed by Avicena Group, Inc.
Investigational

CT-011

CT-011 is a humanized monoclonal antibody directed against a B7 family-associated protein, in patients with advanced haematological malignancies. It is directed against human PD-1 (programmed cell death 1; PDCD1), with immunomodulating and antitumor activities.
Investigational

ELX-02

ELX-02 is under investigation in clinical trial NCT03309605 (Phase 1 Study of ELX-02 in Healthy Adult Subjects).
Investigational
Matched Iupac: … (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-5-[(1R)-1-aminoethyl]-3,4 ... -dihydroxyoxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-[(1R)-1-hydroxyethyl]oxane-3,4-diol …

AT-001

AT-001 is under investigation in clinical trial NCT03062384 (AT-001 for Long-term Preservation of Brain Health in Aging).
Investigational
Matched Iupac: … 2-(8-oxo-7-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-7H,8H-pyrazino[2,3-d]pyridazin-5-yl)acetic …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

EMB-01

EMB-01 is under investigation in clinical trial NCT03797391 (A Dose Escalation Study of EMB-01 in Participants With Advanced/metastatic Solid Tumors).
Investigational

CB-010

CB-010 is a CRISPR-edited allogeneic CAR-T cell therapy targeting CD19. It is being investigated for the treatment of follicular lymphoma.
Investigational

EF-022

EF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic and anti-angiogenic activities.
Investigational

VCN-01

VCN-01 is an investigational, genetically modified human adenovirus encoding human PH20.
Investigational

OT-004

Investigational
Displaying drugs 6276 - 6300 of 12300 in total