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Displaying drugs 6451 - 6475 of 9464 in total
Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS SIALIC ACID-BINDING IG-LIKE LECTIN 8 (SIALOADHESIN FAMILY MEMBER 2, ... SIGLEC-8, SAF-2))HUMANIZED MOUSE MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-450) (VH (HOMO SAPIENS IGHV3 …
Experimental
Matched Synonyms: … (2R)-2-(4-nitrophenyl)oxirane …
Matched Iupac: … (2R)-2-(4-nitrophenyl)oxirane …
Gusperimus has been used in trials studying the treatment of Lupus Nephritis, Wegeners Granulomatosis, and Wegener's Granulomatosis.
Investigational
Matched Salts cas: … 85468-01-5
Azimilide is an investigational class III anti-arrhythmic drug that blocks fast and slow components of the delayed rectifier cardiac potassium channels. It is not approved for use in any country, but is currently in clinical trials in the United States.
Investigational
Matched Iupac: … 1-({[5-(4-chlorophenyl)furan-2-yl]methylidene}amino)-3-[4-(4-methylpiperazin-1-yl)butyl]imidazolidine …
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-3-[(2-{[2-(hydroxysulfanyl …
Experimental
Matched Name: … 2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine …
Matched Iupac: … ({[(2S)-1-(2,6-diamino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate …
Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).
Investigational
Matched Description: … With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2) …
Experimental
Matched Name: … TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE …
Experimental
Matched Name: … 2-Ethylhexyl 4-phenylbenzophenone-2'-carboxylate …
Matched Iupac: … 2-ethylhexyl 2-{[1,1'-biphenyl]-4-carbonyl}benzoate …
Experimental
Matched Synonyms: … 4-hydroxy-2-chromenone ... 4-hydroxychromen-2-one ... 4-hydroxy-2H-1-benzopyran-2-one …
Matched Iupac: … 4-hydroxy-2H-chromen-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Investigational
Matched Synonyms: … 1-piperazinecarboxamide, 4-((2e)-1-oxo-3-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-propen-1-yl)- ... 4-((2E)-1-Oxo-3-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-propen-1-yl)-1-piperazinecarboxamide …
Matched Iupac: … 4-[(2E)-3-(2,6,6-trimethylcyclohex-1-en-1-yl)prop-2-enoyl]piperazine-1-carboxamide …
Experimental
Matched Synonyms: … (2S)-2-amino-3-methylbutan-1-ol ... (S)-(+)-2-Amino-3-methyl-1-butanol …
Matched Iupac: … (2S)-2-amino-3-methylbutan-1-ol …
Investigational
Matched Synonyms: … 1,3-propanediol, 2-amino-2-(2-(2-chloro-4-((3-(phenylmethoxy)phenyl)thio)phenyl)ethyl)- ... 2-amino-2-(2-(2-chloro-4-(3-benzyloxyphenylthio)phenyl)ethyl)-1,3-propanediol …
Matched Iupac: … 2-amino-2-[2-(4-{[3-(benzyloxy)phenyl]sulfanyl}-2-chlorophenyl)ethyl]propane-1,3-diol …
Afamitresgene autoleucel is a specific Peptide Enhanced Affinity Receptor T cell product comprised of autologous CD4 and CD8 positive T cells genetically engineered with an affinity-enhanced T cell receptor to target cancer-testis antigen MAGE-A4
Investigational
Experimental
Matched Synonyms: … (2E)-3-(2-hydroxyphenyl)-2-propenoic acid ... (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid ... (E)-3-(2-Hydroxyphenyl)-2-propenoic acid …
Matched Name: … trans-2-hydroxycinnamic acid …
Matched Iupac: … (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid …
Experimental
Matched Iupac: … [(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy][2-(trimethylazaniumyl)ethoxy]phosphinic acid …
Seletracetam is a pyrrolidone derivative and with a structural similarity to newer generation antiepileptic drug levetiracetam. It binds to the same target as levetiracetam but with higher affinity and has shown potent seizure suppression in models of acquired and genetic epilepsy with high CNS tolerability. It is predicted to have...
Investigational
Matched Synonyms: … (2S)-2-((4S)-4-(2,2-Difluoroethenyl)-2-oxopyrrolidin-1-yl)butanamide …
Matched Iupac: … (2S)-2-[(4S)-4-(2,2-difluoroethenyl)-2-oxopyrrolidin-1-yl]butanamide …
Experimental
Matched Synonyms: … 2-quinolone ... Quinolin-2-ol ... 2(1H)-Quinolinone …
Matched Name: … 2-Hydroxyquinoline …
Matched Iupac: … 1,2-dihydroquinolin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).
Investigational
Matched Synonyms: … IL-2 ... INTERLEUKIN-2 ... Liposome encapsulated recombinant interleukin-2
Matched Name: … Human interleukin-2
Matched Description: … IL-2 and Nivo Rescue in mMEL). ... Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With …
Matched Categories: … Interleukin-2
GSK2798745 is under investigation in clinical trial NCT03372603 (A Study to Assess the Effectiveness and Side Effects of GSK2798745 in Participants With Chronic Cough).
Investigational
Matched Iupac: … 1-{[(5S,7S)-3-[5-(2-hydroxypropan-2-yl)pyrazin-2-yl]-7-methyl-2-oxo-1-oxa-3-azaspiro[4.5]decan-7-yl]methyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
GSK2245035 is under investigation in clinical trial NCT02833974 (Effect of the GSK2245035 on the Allergen-induced Asthmatic Response).
Investigational
Matched Iupac: … 6-amino-2-[(2S)-pentan-2-yloxy]-9-[5-(piperidin-1-yl)pentyl]-8,9-dihydro-7H-purin-8-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
CA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.[A258234,A258239]
Experimental
Matched Synonyms: … -2-carboxylate ... -2-carboxylate ... (S)-methyl 1-((2S,3S)-3-methyl-2-((2S,3S)-3-(propylcarbamoyl)oxirane-2-carboxamido)pentanoyl)pyrrolidine …
Matched Iupac: … -2-carboxylate ... methyl (2S)-1-[(2S,3S)-3-methyl-2-{[(2S,3S)-3-(propylcarbamoyl)oxiran-2-yl]formamido}pentanoyl]pyrrolidine …
Investigational
Matched Synonyms: … 2'-((1r)-1-(((1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl)amino)-(2r)-2-hydroxypropoxy)ethyl)-3-methyl ... 2'-((1r)-1-(((2r)-3-((1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropyl)oxy)ethyl ... 2'-((1r)-1-((2r)-3-((1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)ethyl)-3 …
Matched Iupac: … 2'-[(1R)-1-[(2R)-3-{[1-(4-chloro-3-fluorophenyl)-2-methylpropan-2-yl]amino}-2-hydroxypropoxy]ethyl]-3 …
Displaying drugs 6451 - 6475 of 9464 in total