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Displaying drugs 626 - 650 of 1180 in total

Denenicokin

Denenicokin is under investigation in clinical trial NCT01152788 (Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma).
Investigational
Matched Synonyms: … Recombinant human IL-21 ... L-METHIONYL(HUMAN INTERLEUKIN-21) ... RECOMBINANT HUMAN INTERLEUKIN 21 …

Ocriplasmin

Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Synonyms: … Microplasmin (synthetic human) ... Recombinant human microplasmin …
Matched Description: … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …

Tiotropium

Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.[A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.[A180163,L7084,L7087,L7090,L7093] Tiotropium is more specific for the subset of muscarinic receptors commonly found in the...
Approved
Matched Description: … antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and ... Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and …
Matched Categories: … olodaterol and tiotropium bromide ... formoterol and tiotropium bromide …
Matched Products: … Tiogiva 18 Mikrogramm Hartkapseln mit Pulver zur Inhalation ... Srivasso 18 Mikrogramm Hartkapseln mit Pulver zur Inhalation ... Tiotropium Viatris 18 Mikrogramm Hartkapseln mit Pulver zur Inhalation …

GL-2045

Investigational
Matched Synonyms: … Recombinant human IgG1 Fc multimer ... Recombinant Multimerized Human IgG1 Fc …

Fotemustine

Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Muphoran 200 mg/4ml Pulver und Lösungsmittel zur Herstellung einer Infusionslösung …

Albusomatropin

Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth Hormone Deficiency.
Investigational
Matched Synonyms: … recombinant human serum albumin human growth hormone ... RECOMBINANT HUMAN ALBUMIN-RECOMBINANT HUMAN GROWTH HORMONE FUSION PROTEIN ... HUMAN SERUM ALBUMIN FUSED TO THE N-TERMINUS OF GROWTH HORMONE …
Matched Description: … Albusomatropin has been used in trials studying the treatment of Growth Hormone-Deficiency and Growth …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Hyaluronidase

Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. The action of hyaluronidase was first described in 1936, and named in 1939. Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective...
Approved
Matched Description: … fluids, drugs, and contrast agents. ... Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered ... [L13338] The action of hyaluronidase was first described in 1936, and named in 1939. …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Products: … . - Pulver zur Herstellung einer Injektionslösung …

Lanthanum carbonate

Lanthanum carbonate is a phosphate binder marketed under the trade name Fosrenol by Shire Pharmaceuticals. It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects. It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to...
Approved
Matched Description: … It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse ... phosphate levels, primarily in patients with chronic kidney disease, by binding to dietary phosphate and …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … Fosrenol 750 mg Pulver zum Einnehmen ... Fosrenol 1000 mg Pulver zum Einnehmen …

Pecan

Pecan allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Carya illinoinensis seed …

Yellow fever vaccine

Yellow fever vaccine prevents against Yellow Fever, a viral hemorrhagic disease caused by the transmission of a flavivirus through the bite of an infected mosquito. Symptoms of Yellow fever can range from asymptomatic, to mild flu-like illness, to more severe symptoms such as shock, jaundice, internal bleeding, and organ failure...
Approved
Investigational
Matched Description: … asymptomatic, to mild flu-like illness, to more severe symptoms such as shock, jaundice, internal bleeding, and ... Interestingly, Yellow fever got its name from the characteristic yellowing of the skin and eyes that ... of yellow fever in pediatric patients 9 months of age and older. …
Matched Products: … STAMARIL Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension Gelbfieber - Lebendimpfstoff …

Plasminogen

Plasminogen is a pro-enzyme (i.e. a zymogen) which is cleaved to form plasmin - also known as fibrinolysin - as part of the fibrinolytic pathway that breaks down fibrin blood clots. This pathway is activated when a clot is no longer needed or to prevent a clot from extending beyond...
Approved
Matched Synonyms: … Human plasminogen ... plasminogen, human-tvmh …
Matched Description: … [L34615] It is the first and only FDA-approved treatment for this condition, which causes wood-like lesions ... [L34635] In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …

C-peptide

C-peptide is under investigation in clinical trial NCT00278980 (Effect of C-peptide on Diabetic Peripheral Neuropathy).
Investigational
Matched Synonyms: … Human c-peptide ... Human proinsulin c-peptide ... Proinsulin c-peptide (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Protein C

Protein C is an endogenously occurring plasma protein that plays a key role within the coagulation cascade. Protein C is a zymogen, or enzyme precursor, of a vitamin K-dependent anticoagulant glycoprotein (serine protease) that is synthesized in the liver. It is converted by the thrombin/thrombomodulin-complex on the endothelial cell surface...
Approved
Matched Synonyms: … Human protein C ... Protein C human ... Protein C concentrate human …
Matched Description: … thrombosis and purpura fulminans. ... its effect by inactivating essential components of the coagulation cascade (specifically factors V and ... VIII), which leads to a decrease in thrombin formation, and therefore a reduction in clot formation. …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Pulver und Lösungsmittel zur Herstellung einer Injektionslösung …
Matched Categories: … Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …

Netakimab

Netakimab is under investigation in clinical trial NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and Safety of BCD-085 in Patients With Ankylosing Spondylitis).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human interleukin 17) (human-lama glama monoclonal heavy chain), disulfide with ... human monoclonal light chain, dimer …
Matched Description: … NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Human interferon omega-1

Human interferon omega 1 (IFN-omega 1 = IFN-alpha II1) is a recently discovered protein structurally related to IFN-alpha and -beta. It occurs naturally in the human body and is currently being manufactured by Intarcia through genetic engineering. There are multiple routes for administration of omega interferon: injection, an implantable subcutaneous...
Investigational
Matched Synonyms: … Human interferon omega 1 …
Matched Name: … Human interferon omega-1 …
Matched Description: … It occurs naturally in the human body and is currently being manufactured by Intarcia through genetic ... related to IFN-alpha and -beta. ... It has been investigated both in single and combination treatment. …

cryopreserved human liver cells

Vesta Therapeutics is a privately held company developing cell therapeutics for liver repair and regeneration. The Company's technology is centered on the isolation, expansion, and cryopreservation of liver cells (human hepatocytes) obtained from organ donor livers that are not suitable for whole organ transplantation.
Investigational
Matched Name: … cryopreserved human liver cells …
Matched Description: … Vesta Therapeutics is a privately held company developing cell therapeutics for liver repair and regeneration ... The Company's technology is centered on the isolation, expansion, and cryopreservation of liver cells ... (human hepatocytes) obtained from organ donor livers that are not suitable for whole organ transplantation …

Palucorcel

Palucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells. Developed by Janssen Biotech, it is being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and macular degeneration.
Investigational
Matched Synonyms: … Human umbilical tissue-derived cells ... HUMAN UMBILICAL TISSUE-DERIVED CELLS (ALLOGENIC) …
Matched Description: … being investigated for the treatment of various conditions such as amyotrophic lateral sclerosis (ALS) and ... Palucorcel is an investigational stem cell therapy consisting of human umbilical tissue-derived cells …

rhMBL

rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections in individuals with low levels of Mannose-Binding Lectin (MBL). Over 10 percent of the general population is estimated to be MBL-deficient. Natural MBL is a 400-700kDa oligomer made of 3 identical 32kDa peptide...
Investigational
Matched Synonyms: … Recombinant human mannan-binding protein ... Recombinant human mannose-binding lectin …
Matched Description: … rhMBL is a protein therapeutic being developed by Enzon for the prevention and treatment of severe infections …

Mapatumumab

Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-hodgkin's Lymphoma (NHL)).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human trail-r1) (human monoclonal trm-1 heavy chain), disulfide with human monoclonal ... Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy ... Immunoglobulin g1, anti-(human cytokine receptor dr4 (death receceptor 4)) (human monoclonal trm-1 heavy …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Attapulgite

Attapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the Southeastern United States. When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it has often been used in antidiarrheal medications. Until...
Approved
Vet approved
Matched Description: … When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … PULAREX …

Brazikumab

Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease).
Investigational
Matched Synonyms: … Immunoglobulin g2, anti-(human interleukin 23) (human monoclonal medi2070 heavy chain), disulfide with ... human monoclonal medi2070 .lambda. …
Matched Description: … Brazikumab is under investigation in clinical trial NCT03759288 (An Active and Placebo-controlled Study …

Topotecan

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Topotecan Hikma 1 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung ... Topotecan Hikma 4 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung …

Beractant

Beractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Considered a natural source of surfactant as it is made from bovine lung extract, beractant contains a mixture of phospholipids, neutral lipids, fatty acids, and surfactant-associated proteins such as SP-B and SP-C. The...
Approved
Matched Description: … surfactant-associated proteins such as SP-B and SP-C. ... from bovine lung extract, beractant contains a mixture of phospholipids, neutral lipids, fatty acids, and ... It is suspended in 0.9% sodium chloride solution, and heat-sterilized. …
Matched Products: … Alveofact 45 mg/ml Pulver und Lösungsmittel zur Herstellung einer Suspension zur endotracheopulmonalen …

Zanolimumab

Zanolimumab is a fully human monoclonal antibody directed against CD4.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN, ANTI-(HUMAN CD4 ANTIGEN) (HUMAN MONOCLONAL 6G5 HEAVY CHAIN), DISULPHIDE WITH HUMAN MONOCLONAL …
Matched Description: … Zanolimumab is a fully human monoclonal antibody directed against CD4. …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Urabrelimab

Investigational
Matched Synonyms: … Immunoglobulin igg4, anti-(human cd47) (human monoclonal srf231 .gamma.4-chain), disulfide with human …
Displaying drugs 626 - 650 of 1180 in total