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Displaying drugs 626 - 650 of 704 in total
TPX-4589
TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Investigational
Matched Synonyms: … Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload …
Matched Description: … TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and …
Matched Description: … TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and …
Viagenpumatucel-L
Viagenpumatucel-L is under investigation in clinical trial NCT02117024 (A Phase 2 Study of Viagenpumatucel-l (HS-110) in Patients With Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Gp96-igg1-fc fusion protein and hla-a1 expressing, irradiated ad-100 whole cell vaccine …
TN-401
TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.
Investigational
Matched Synonyms: … A native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and …
Matched Description: … TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and …
VOR33
VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …
Atacicept
Atacicept is a recombinant fusion protein combined with the extracellular ligand binding portion of TACI.
Investigational
Matched Synonyms: … Human Transmembrane Activator and CAML Interactor (TACI) Immunoglobulin G1 Fc Domain Fusion Protein ( …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cotsiranib
Investigational
Matched Synonyms: … interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 (TGF-beta 1) and …
Hiltonol
Investigational
Matched Synonyms: … homopolymer, complex with 5'-inosinic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and ... L-lysine, homopolymer, compd. with cellulose carboxymethyl ether and 5'-inosinic acid homopolymer complex ... homopolymer, complex with 5'-cytidylic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Pacanalotamab
Investigational
Matched Synonyms: … engager antibody with a single chain fc moiety that binds to b cell maturation antigen surface receptor and …
Ergidina
Ergidina is a recombinant human minibody against complement component C5 fused with RGD-motif.
Investigational
Matched Synonyms: … Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 and the cyclic …
Spanlecortemlocel
Investigational
Matched Synonyms: … ALLOGENEIC UMBILICAL CORD BLOOD-DERIVED HEMATOPOIETIC STEM AND PROGENITOR CELLS MGTA-456 ... Allogeneic umbilical cord blood (UCB) cell therapy product consisting of two cell fractions (CD34 enriched and …
Hybrid Between B and C Type Hemes (Protoporphyrin Ixcontaining Fe)
Experimental
Matched Name: … Hybrid Between B and C Type Hemes (Protoporphyrin Ixcontaining Fe) …
Matched Iupac: … 3-[20-(2-carboxyethyl)-15-ethenyl-10-ethyl-5,9,14,19-tetramethyl-2,22,23,25-tetraaza-1-ferraoctacyclo …
Matched Iupac: … 3-[20-(2-carboxyethyl)-15-ethenyl-10-ethyl-5,9,14,19-tetramethyl-2,22,23,25-tetraaza-1-ferraoctacyclo …
Taniraleucel
Investigational
Matched Synonyms: … Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell ... The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, …
Tavokinogene telseplasmid
Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.
Investigational
Matched Synonyms: … Dna plasmid containing genes coding for the human interleukin 12 (il-12) p35 and p40 subunits that are ... separated by an internal ribosomal entry site (ires) and under the control of a single cytomegalovirus …
Posoleucel
Investigational
Matched Synonyms: … specific T lymphocytes targeting BK virus, cytomegalovirus, human herpes virus-6, Epstein Barr virus, and …
AD-214
Investigational
Matched Synonyms: … Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 and …
Sabestomig
Sabestomig is under investigation in clinical trial NCT05216835 (Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma).
Investigational
Matched Synonyms: … 3, TIM3, TIM-3, TIMD3, CD366)], humanized and Ho ... HAVCR2 (hepatitis A virus cellular receptor 2, T cell immunoglobulin and mucin domains family member ... Immunoglobulin G1-kappa/lambda, anti-[Homo sapiens PDCD1 (programmed cell death 1, PD1, PD-1, CD279) and …
Matched Description: … Sabestomig is under investigation in clinical trial NCT05216835 (Safety and Preliminary Efficacy Assessment …
Matched Description: … Sabestomig is under investigation in clinical trial NCT05216835 (Safety and Preliminary Efficacy Assessment …
PEP0101
PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
Fepixnebart
Fepixnebart is under investigation in clinical trial NCT04456686 (Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Osteoarthritis).
Investigational
Matched Synonyms: … Ly3016859 (humanized monoclonal antibody to human tgf.alpha. and epiregulin) ... IMMUNOGLOBULIN G4 (226-PROLINE,232-ALANINE,233-ALANINE,DE-C-TERMINAL-LYSINE), ANTI-(HUMAN EPIREGULIN AND …
Nendratareotide uzatansine
Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated to the cytotoxin mertansine.
Investigational
Matched Synonyms: … Peptide-drug conjugate combining [(Tyr3,Cys8) octreotate amide] and N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl …
TRK-001
TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Investigational
Matched Synonyms: … Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and …
ST-101
ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease.
Investigational
Matched Description: … ST-101 is a small peptide antagonist of C/EBPβ and T-type calcium channel activator. ... ST101 has been used in trials studying the treatment of Essential Tremor and Alzheimer's Disease. …
Zenocutuzumab
Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and …
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
TVI-Brain-1
Investigational
Matched Synonyms: … Attenuated autologous cancer cells and granulocyte macrophage colony stimulating factor in combination …
Lym-1-I-131
Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.
Investigational
Matched Synonyms: … Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphoma …
Displaying drugs 626 - 650 of 704 in total