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Displaying drugs 626 - 650 of 956 in total

Adenosine

The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] and …
Matched Mixtures name: … Lip And Hand Camellia ... Lip And Hand Wild Rose ... Lip And Hand Shea Butter …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … misoli Power Snail and Collagen Hydrog el Mask Pack ... rootree Treetherapy Rejuvenating Eye and Neck Treatment …

Florbetapir (18F)

Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to the compound florbetapir, a molecule that binds with high affinity to beta amyloid plaque, a peptide that plays a key role in Alzheimer's Disease pathogenesis. Marketed as the product Amyvid, florbetapir 18F is indicated for positron emission tomography...
Approved
Investigational
Matched Synonyms: … florbetapir-fluorine-18 …
Matched Description: … density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and ... Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to ... The radionucleide fluorine-18 was chosen as it has a half life of 110 minutes allowing it to accumulate …
Matched Categories: … Fluorine Radioisotopes …

1,2,5-THIADIAZOLIDIN-3-ONE-1,1-DIOXIDE

Experimental
Matched Name: … 1,2,5-THIADIAZOLIDIN-3-ONE-1,1-DIOXIDE …

5-fluoro-beta-L-gulosyl fluoride

Experimental
Matched Name: … 5-fluoro-beta-L-gulosyl fluoride …

4-AMINO-2-TRIFLUOROMETHYL-5-HYDROXYMETHYLPYRIMIDINE PYROPHOSPHATE

Experimental
Matched Name: … 4-AMINO-2-TRIFLUOROMETHYL-5-HYDROXYMETHYLPYRIMIDINE PYROPHOSPHATE …

Hydronidone

Hydronidone has antifibrotic activity.
Investigational
Matched Synonyms: … N-(4-Hydroxyphenyl)-5-methyl-2-pyridone …

Nefazodone

Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb. Its sale was discontinued in 2003 in some countries, due to the small possibility of hepatic (liver) injury. Drug-induced hepatic injuries were associated with an risk of elevated need for a liver transplant, or even death, with...
Approved
Withdrawn
Matched Description: … Nefazodone hydrochloride (trade name Serzone) is an antidepressant drug marketed by Bristol-Myers Squibb …
Matched Salts name: … Nefazodone hydrochloride …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors ... Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … Nefazodone hydrochloride ... Nefazodone Hydrochloride …

Ketotifen

Ketotifen is a benzocycloheptathiophene derivative with potent antihistaminic and mast cell stabilizing properties. It has a similar structure to some other first-generation antihistamines such as cyproheptadine and azatadine. Ketotifen was first developed in Switzerland in 1970 by Sandoz Pharmaceuticals and was initially marketed for the treatment of anaphylaxis. In the...
Approved
Matched Description: … allergic symptoms and disorders,[A231204] including urticaria, mastocytosis, and food allergy. ... Ketotifen is a benzocycloheptathiophene derivative[A231204] with potent antihistaminic and mast cell ... It has a similar structure to some other first-generation antihistamines such as [cyproheptadine] and …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up Eye Itch Relief …

Daptomycin

Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Description: … -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE). ... with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and ... A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Daptomycin in Sodium Chloride …

Norepinephrine

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... It is also found in plants and is used pharmacologically as a sympathomimetic. ... Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse …
Matched Categories: … Epinephrine and similars ... Adrenergic and Dopaminergic Agents ... Alpha-and Beta-adrenergic Agonists …
Matched Products: … Norepinephrine Bitartrate In Sodium Chloride …

Moexipril

Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
Approved
Matched Description: … Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems. …
Matched Mixtures name: … Moexipril Hydrochloride and Hydrochlorothiazide ... Moexipril Hydrochloride and Hydrochlorothiazide ... Moexipril Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Moexipril Hydrochloride …
Matched Categories: … ACE Inhibitors and Diuretics ... moexipril and diuretics …
Matched Products: … Moexipril Hydrochloride ... Moexipril hydrochloride …

Naloxone

Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist,...
Approved
Vet approved
Matched Description: … , and even death. ... Frequently also carried by medical and emergency personnel and at events known to be associated with ... [A234589] It's important to note that naloxone only works on opioid receptors within the body, and is …
Matched Mixtures name: … Pentazocine Hydrochloride and Naloxone Hydrochloride ... Pentazocine Hydrochloride and Naloxone Hydrochloride ... Pentazocine and naloxone hydrochlorides …
Matched Salts name: … Naloxone hydrochloride ... Naloxone hydrochloride dihydrate …
Matched Categories: … Alimentary Tract and Metabolism ... tilidine and naloxone ... oxycodone and naloxone ... pentazocine and naloxone ... hydromorphone and naloxone …
Matched Products: … Naloxone Hydrochloride ... NALOXONE HYDROCHLORIDE ... Naloxone Hydrochloride Fine …

Fludeoxyglucose (18F)

Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with Positron Emission Tomography (PET). It is administered by intravenous injection.
Approved
Investigational
Matched Synonyms: … Fluorine (18F) fludeoxyglucose …
Matched Categories: … Indicators and Reagents …

Tobramycin

Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Description: … concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and ... [A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to ... L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and …
Matched Mixtures name: … Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone …
Matched Salts name: … Tobramycin hydrochloride …
Matched Products: … Tobramycin in Sodium Chloride …

Etevritamab

Investigational
Matched Synonyms: … RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB) VARIANT III (EGFRVIII)) AND …

Fazpilodemab

Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis).
Investigational
Matched Synonyms: … immunoglobulin G1-kappa, anti-[Homo sapiens KLB (klotho beta, b-Klotho)] and anti-[Homo sapiens FGFR1 …
Matched Description: … Fazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and …

Donepezil

In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Description: … with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. ... derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and ... Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Salts name: … Donepezil hydrochloride ... Donepezil hydrochloride monohydrate …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … ANDEM 5 MG FILM TABLET, 14 ADET ... ANDEM 5 MG FILM TABLET, 28 ADET ... ANDEM 10 MG FILM TABLET, 14 ADET …

Dobutamine

A beta-1 agonist catecholamine that has cardiac stimulant action without evoking vasoconstriction or tachycardia. It is proposed as a cardiotonic after myocardial infarction or open heart surgery.
Approved
Matched Mixtures name: … Dobutamine Hydrochloride in Dextrose …
Matched Salts name: … Dobutamine hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Products: … Dobutamine Hydrochloride ... DOBUTAMINE HYDROCHLORIDE ... Dobutamine Hydrochloride in Dextrose …

Cocaine

An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Description: … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... the eye, ear, nose, and throat. ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse …
Matched Salts name: … Cocaine hydrochloride …
Matched Categories: … Analgesics and Anesthetics …
Matched Products: … Cocaine Hydrochloride ... Cocaine Hydrochloride Nasal ... Cocaine Hydrochloride Top Sol 40mg/ml …

Proparacaine

Proparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
Approved
Vet approved
Matched Description: … It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt. …
Matched Mixtures name: … Fluorescein Sodium and Proparacaine Hydrochloride …
Matched Salts name: … Proparacaine hydrochloride …
Matched Products: … Proparacaine Hydrochloride ... PMS-proparacaine Hydrochloride Oph Soltn 0.5% …

Triethylenetetramine

Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective chelator. It is a structural analog of linear polyamine compounds, spermidine and spermine. TETA was first developed in Germany in 1861 and its chelating properties were first recognized in 1925. Initially approved by the FDA in 1985...
Approved
Investigational
Matched Description: … It is a structural analog of linear polyamine compounds, [spermidine] and [spermine]. ... Triethylenetatramine (TETA), also known as trientine, is a potent and selective copper (II)-selective ... TETA was first developed in Germany in 1861 and its chelating properties were first recognized in 1925 …
Matched Salts name: … Trientine hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Matched Products: … Trientine Hydrochloride ... Trientine hydrochloride …

Tegavivint

Investigational
Matched Synonyms: … 9,10-anthracenedione, 2,7-bis(((3r,5s)-3,5-dimethyl-1-piperidinyl)sulfonyl)-, 9,10-dioxime, rel- …

Dalteparin

Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant. It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000....
Approved
Matched Description: … composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and ... LMWHs have a more predictable response, a greater bioavailability, and a longer anti-Xa half life than …
Matched Salts name: … Dalteparin sodium …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … DALTEPARINA SODICA INYECCIÒN 5000 UI ... DALTEPARINA SODICA 2500 UI INYECCION …

Ketamine

Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor...
Approved
Vet approved
Matched Description: … it produced minor hallucinogenic effects and shorter psychotomimetic effects. ... It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, ... It was FDA approved in 1970, and from there, it has been used as an anesthetic for children or patients …
Matched Salts name: … Ketamine hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Ketamine Hydrochloride ... KETAMINE HYDROCHLORIDE ... Ketamine Hydrochloride Injection USP …

N-methylnicotinamide

N-methylnicotinamide is an experimental drug with no approved indication or marketed formulation. It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine.
Experimental
Matched Synonyms: … 3-(Methylcarbamoyl)pyridine ... 3-(N-Methylcarbamoyl)pyridine …
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism …
Displaying drugs 626 - 650 of 956 in total