Displaying drugs 6476 - 6500 of 8039 in total
Taprenepag
Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.
Investigational
Matched Description: … Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle …
GSK-376501
GSK376501 has been used in trials studying the treatment and diagnostic of Type 2 Diabetes Mellitus.
Investigational
Matched Description: … GSK376501 has been used in trials studying the treatment and diagnostic of Type 2 Diabetes Mellitus. …
Rolofylline
Rolofylline is under clinical development by pharmaceutical company NovaCardia for the treatment of congestive heart failure.
Investigational
Matched Description: … Rolofylline is under clinical development by pharmaceutical company NovaCardia for the treatment of congestive …
Nerispirdine
Nerispirdine has been used in trials studying the treatment of Neuritis, Optic Nerve, and Multiple Sclerosis.
Investigational
Matched Description: … Nerispirdine has been used in trials studying the treatment of Neuritis, Optic Nerve, and Multiple Sclerosis …
Concizumab
Concizumab has been used in trials studying the treatment of Haemophilia A and Congenital Bleeding Disorder.
Investigational
Matched Description: … Concizumab has been used in trials studying the treatment of Haemophilia A and Congenital Bleeding Disorder …
Oleandrin
Oleandrin has been used in trials studying the treatment of Lung Cancer and Chemotherapeutic Agent Toxicity.
Experimental
Investigational
Matched Description: … Oleandrin has been used in trials studying the treatment of Lung Cancer and Chemotherapeutic Agent Toxicity …
Intoplicine
Intoplicine has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Description: … Intoplicine has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol …
Mitolactol
Mitolactol has been used in trials studying the treatment of Brain and Central Nervous System Tumors.
Investigational
Matched Description: … Mitolactol has been used in trials studying the treatment of Brain and Central Nervous System Tumors. …
Sulfobromophthalein
Sulfobromophthalein or otherwise called bromsulphthalein is used as a test of liver function in humans .
Experimental
Matched Description: … Sulfobromophthalein or otherwise called bromsulphthalein is used as a test of liver function in humans …
Ginsenoside B2
Ginsenoside B2 is under investigation in clinical trial NCT00781534 (A Clinical Trial of Ginseng in Diabetes).
Investigational
Matched Description: … Ginsenoside B2 is under investigation in clinical trial NCT00781534 (A Clinical Trial of Ginseng in Diabetes …
Konjac mannan
Konjac mannan is under investigation in clinical trial NCT01709955 (The Effects of Glucomannan on Weight Loss).
Investigational
Matched Description: … Konjac mannan is under investigation in clinical trial NCT01709955 (The Effects of Glucomannan on Weight …
Dezamizumab
Dezamizumab is under investigation in clinical trial NCT03417830 (Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging).
Investigational
Matched Description: … Dezamizumab is under investigation in clinical trial NCT03417830 (Biodistribution of 89Zirconium-labelled …
Ebopiprant
Ebopiprant is under investigation in clinical trial NCT03369262 (Poc Study of OBE022 in Threatened Preterm Labour).
Investigational
Matched Description: … Ebopiprant is under investigation in clinical trial NCT03369262 (Poc Study of OBE022 in Threatened Preterm …
Esflurbiprofen
Esflurbiprofen is under investigation in clinical trial NCT03434197 (Safety and Efficacy of SFPP in Knee Osteoarthritis).
Investigational
Matched Description: … Esflurbiprofen is under investigation in clinical trial NCT03434197 (Safety and Efficacy of SFPP in Knee …
Rivenprost
Rivenprost is under investigation in clinical trial NCT00296556 (Therapeutic Study of ONO-4819CD for Ulcerative Colitis).
Investigational
Matched Description: … Rivenprost is under investigation in clinical trial NCT00296556 (Therapeutic Study of ONO-4819CD for …
JTC-801 free base
An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment.
Investigational
Matched Description: … An antagonist of nociceptin receptor and analgesic agent, evaluated for its use in cancer treatment. …
rAAV9-rsATP7A
A recombinant adeno-associated viral vector gene therapy under investigation for the treatment of Menkes disease.
Investigational
Matched Description: … A recombinant adeno-associated viral vector gene therapy under investigation for the treatment of Menkes …
Pozanicline
ABT-089 is a neuronal nicotinic acetylcholine receptor agonist that may have therapeutic utility for the treatment of several neurological disorders including Alzheimer, Attention Deficit Hyperactivity Disorder and Schizophrenia/Schizoaffective disorders. In radioligand binding studies, ABT-089 has shown selectivity toward the alpha4beta2 nAChR subtype as compared to the alpha7 and alpha1beta1deltagamma nAChR...
Investigational
Matched Description: … neuronal nicotinic acetylcholine receptor agonist that may have therapeutic utility for the treatment of ... Neuronal nicotinic acetylcholine receptors (nAChRs) modulate the release of several important neurotransmitters …
R673
R673 is a novel NK1 antagonist that penetrates the blood-brain barrier, has excellent safety and tolerability and shows low P450-based drug interaction potential. The phase II program for treatment of depression and anxiety is ongoing in the US and EU.It is not clear how tachykinin antagonists exert their effect, but...
Investigational
Matched Description: … The phase II program for treatment of depression and anxiety is ongoing in the US and EU.It is not clear ... tachykinin antagonists exert their effect, but SP levels have been commonly linked to the functioning of …
XMT-1001
XMT-1001 is a polymer-based prodrug of camptothecin (CPT), a well-characterized topoisomerase I inhibitor with potent anti-tumor activity. It is a water-soluble macromolecular conjugate of camptothecin (CPT). In this novel CPT pro-drug, CPT is conjugated with a 70 kDa biodegradable hydrophilic polyacetal, poly (1-hydroxymethylene hydroxylmethylformal). XMT-1001 has demonstrated an improved therapeutic...
Investigational
Matched Description: … It is a water-soluble macromolecular conjugate of camptothecin (CPT). ... XMT-1001 is a polymer-based prodrug of camptothecin (CPT), a well-characterized topoisomerase I inhibitor …
Octacosanol
1-octacosanol is a straight-chain aliphatic 28-carbon primary fatty alcohol that is used as a nutritional supplement. This high–molecular-weight organic compound is the main component of a natural product wax extracted from plants . 1-octacosanol is reported to possess cholesterol-lowering effects, antiaggregatory properties, cytoprotective use, and ergogenic properties . It has...
Nutraceutical
Matched Description: … It has been studied as a potential therapeutic agent for the treatment of Parkinson's disease. ... This high–molecular-weight organic compound is the main component of a natural product wax extracted …
Dithiazanine
Dithiazanine is a highly potent anthelmintic, introduced in 1959 for the treatment of strongyloid worms and whipworms. However, its use is severely limited due to its toxicity. Dithiazanine iodide was associated with eight fatal cases of severe acidosis and shock between 1961 and 1964. Dithiazanine iodide has been withdrawn from...
Vet approved
Withdrawn
Matched Description: … Dithiazanine is a highly potent anthelmintic, introduced in 1959 for the treatment of strongyloid worms ... Dithiazanine iodide was associated with eight fatal cases of severe acidosis and shock between 1961 and …
MVC-COV1901
MVC-COV1901 is a vaccine candidate developed and commercialized by Medigen Vaccine Biologics Corporation. The vaccine candidate contains a perfusion form of the SARS-Cov2 recombinant spike protein. Medigen has combined forces with Dynavax, which offers an advanced adjuvant, CpG 1018 (also known as ISS-1018), for use with its vaccine. As of...
Investigational
Matched Description: … The vaccine candidate contains a perfusion form of the SARS-Cov2 recombinant spike protein. ... As of September 2020, the vaccine candidate is in Phase 1 clinical trials to assess its safety and immunogenicity …
NOX-700
NOX-700, an new orally active dithiocarbamate-based nitric oxide (NO) blocking agent that is in development for the treatment of diabetes mellitus (type 2 diabetes). In animal studies, NOX-700 lowered serum glucose, improved glucose tolerance, and reduced the percentage of total glycated hemoglobin. Immunohistochemical studies on
pancreatic tissue also showed that...
Investigational
Matched Description: … active dithiocarbamate-based nitric oxide (NO) blocking agent that is in development for the treatment of ... animal studies, NOX-700 lowered serum glucose, improved glucose tolerance, and reduced the percentage of ... It has since been found that oxidative signaling of the redox-sensitive transcription factor, NF-κB, …
Irofulven
A novel anti-cancer compound synthesized by scientists at the University of California, San Diego more than a decade ago from toxins of the poisonous jack-o-lantern mushroom, has been granted “fast track” status by the U.S. Food and Drug Administration (FDA) after demonstrating promise against one of the most deadly cancers....
Investigational
Matched Description: … A novel anti-cancer compound synthesized by scientists at the University of California, San Diego more ... than a decade ago from toxins of the poisonous jack-o-lantern mushroom, has been granted “fast track ... Food and Drug Administration (FDA) after demonstrating promise against one of the most deadly cancers …
Displaying drugs 6476 - 6500 of 8039 in total