Displaying drugs 6526 - 6550 of 8282 in total
Lutikizumab
Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis).
Investigational
Matched Description: … in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of …
Olacaftor
Olacaftor is under investigation in clinical trial NCT02951182 (A Study Evaluating the Safety and Efficacy of VX-440 Combination Therapy in Subjects With Cystic Fibrosis).
Investigational
Matched Description: … Olacaftor is under investigation in clinical trial NCT02951182 (A Study Evaluating the Safety and Efficacy of …
Racemetyrosine
Racemetyrosine is under investigation in clinical trial NCT03512756 (A Randomized Phase 2/3 Multi-center Study of SM-88 in Patients With Metastatic Pancreatic Cancer).
Investigational
Matched Description: … Racemetyrosine is under investigation in clinical trial NCT03512756 (A Randomized Phase 2/3 Multi-center Study of …
Pidacmeran
Pidacmeran is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-2019 in Healthy Adults).
Investigational
Matched Description: … is under investigation in clinical trial NCT04380701 (A Trial Investigating the Safety and Effects of …
Cadonilimab
Cadonilimab is under investigation in clinical trial NCT04220307 (A Study of a PD-1/CTLA-4 Bispecific Antibody AK104 in Patients With Metastatic Nasopharyngeal Carcinoma).
Investigational
Matched Description: … Cadonilimab is under investigation in clinical trial NCT04220307 (A Study of a PD-1/CTLA-4 Bispecific …
TSHA-118
TSHA-118 is a self-complementary AAV9 gene replacement therapy designed to express a human codon-optimized CLN1 transgene for the treatment of CLN1 disease.
Experimental
Matched Description: … gene replacement therapy designed to express a human codon-optimized CLN1 transgene for the treatment of …
Linvoseltamab
Linvoseltamab is an investigational bispecific antibody. It promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma cells with CD3-expressing T cells.
Investigational
Matched Description: … It promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma cells with CD3-expressing …
BHV-5000
BHV-5000 is an orally bioavailable, low-trapping, potent N-methyl-D-aspartate (NMDA) receptor antagonist. The active metabolite of BHV-5000 is lanicemine.
Investigational
Matched Description: … The active metabolite of BHV-5000 is [lanicemine].[L46446] …
Bifidobacterium Longum Infantis 35624
Bifidobacterium Longum Infantis 35624 is a probiotic being investigated for the treatment of gastrointestinal disorders, such as Crohn's disease and irritable bowel syndrome.[A259872, A259877]
Investigational
Matched Description: … Bifidobacterium Longum Infantis 35624 is a probiotic being investigated for the treatment of gastrointestinal …
ssCART-19 cells
ssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6).
Investigational
Matched Description: … ssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a …
Ongericimab
Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and Safety of JS002 in Patients With Heterozygous Familial Hypercholesterolemia (Hefh).).
Investigational
Matched Description: … Ongericimab is under investigation in clinical trial NCT05325203 (A Study to Evaluate the Efficacy and Safety of …
Lunsekimig
Lunsekimig is under investigation in clinical trial NCT06102005 (Dose Ranging Study of Lunsekimig Compared With Placebo-control in Adult Participants With Moderate-to-severe Asthma).
Investigational
Matched Description: … Lunsekimig is under investigation in clinical trial NCT06102005 (Dose Ranging Study of Lunsekimig Compared …
Deudomperidone
Deudomperidone is under investigation in clinical trial NCT05832151 (A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adults With Diabetic Gastroparesis).
Investigational
Matched Description: … Deudomperidone is under investigation in clinical trial NCT05832151 (A Study to Evaluate the Efficacy and Safety of …
Tivanisiran
Tivanisiran is under investigation in clinical trial NCT03108664 (HELIX, a Double-masked Study of SYL1001 in Patients With Moderate to Severe Dry Eye Disease (DED)).
Investigational
Matched Description: … Tivanisiran is under investigation in clinical trial NCT03108664 (HELIX, a Double-masked Study of SYL1001 …
SPH-3127
SPH-3127 is under investigation in clinical trial NCT05359068 (Study to Evaluate the Efficacy and Safety of SPH3127 in Patients With Mild-moderate Essential Hypertension).
Investigational
Matched Description: … 3127 is under investigation in clinical trial NCT05359068 (Study to Evaluate the Efficacy and Safety of …
Arketamine
Arketamine is under investigation in clinical trial NCT05414422 (A Randomized, Placebo-controlled, Double-blind Study to Assess Safety and Efficacy of PCN-101 in TRD).
Investigational
Matched Description: … trial NCT05414422 (A Randomized, Placebo-controlled, Double-blind Study to Assess Safety and Efficacy of …
Tetraethylammonium
Tetraethylammonium is an experimental drug with no approved indication or marketed formulation. The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued. As an experimental agent, tetraethylammonium is used in its salt forms such as tetraethylammonium chloride and tetraethylammonium bromide....
Experimental
Investigational
Matched Description: … The most common use of tetraethylammonium presently is as a pharmacological research agent that blocks ... Its mechanism of action is still being investigated, but it is known that tetraethylammonium blocks autonomic ... Because of its inhibitory actions at the autonomic ganglia, tetraethylammonium was thought to be a potential …
Serrapeptase
Serrapeptase is a proteolytic enzyme preparation used concomitantly with an antibiotic in osteoarticular infections. Serratiopeptidase is under investigation in clinical trial NCT02493179 (Efficacy Evaluation of the (Serodase 5 mg Tablet) in the Treatment of Inflammation After Third Molar Surgery).
Investigational
Matched Description: … 5 mg Tablet) in the Treatment of Inflammation After Third Molar Surgery). ... Serratiopeptidase is under investigation in clinical trial NCT02493179 (Efficacy Evaluation of the (Serodase …
SOBI-003
SOBI-003 is a chemically modified variant of a recombinant human sulfamidase. It is under investigation in clinical trial NCT03811028 (A Study to Assess the Safety, Tolerability, and Efficacy of Long-term SOBI003 Treatment in Pediatric MPS IIIA Patients).
Investigational
Matched Description: … SOBI-003 is a chemically modified variant of a recombinant human sulfamidase. ... investigation in clinical trial NCT03811028 (A Study to Assess the Safety, Tolerability, and Efficacy of …
Amitraz
Amitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. Amitraz presents insect repellent effects and hence, it can be used as an insecticide and pesticide. Its insecticide effect is due to its agonistic activity in the alpha-adrenergic system, its interaction with...
Experimental
Vet approved
Matched Description: … of dogs. ... the synthesis of monoamine oxidases and prostaglandins. ... its interaction with the octopamine receptors in the central nervous system and its driven inhibition of …
Dichlorvos
Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products from insect infestations. The compound has been available on the market since 1961 and its use is a controversial topic...
Vet approved
Matched Description: … used as an insecticide for the control of indoor pests and for the protection of stored products from ... Dichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the _organophosphate_ class, frequently …
D-Aspartic Acid
The D-isomer of aspartic acid. [PubChem]
Experimental
Matched Description: … The D-isomer of aspartic acid. [PubChem] …
Malonaldehyde
Malonaldehyde is the dialdehyde of malonic acid.
Experimental
Matched Description: … Malonaldehyde is the dialdehyde of [malonic acid]. …
2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoic acid
Metabolic product of biphenyl; from Pseudomonas putida.
Experimental
Matched Description: … Metabolic product of biphenyl; from Pseudomonas putida. …
Quinaprilat
The active metabolite of the prodrug quinapril.
Experimental
Matched Description: … The active metabolite of the prodrug [quinapril]. …
Displaying drugs 6526 - 6550 of 8282 in total