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Displaying drugs 6601 - 6625 of 7440 in total
Tezampanel
Tezampanel is an AMPA receptor antagonist.
Investigational
Matched Iupac: … (3S,4aR,6R,8aR)-6-[2-(1H-1,2,3,4-tetrazol-5-yl)ethyl]-decahydroisoquinoline-3-carboxylic acid …
L-778123
Experimental
Matched Iupac: … 4-[(5-{[4-(3-chlorophenyl)-3-oxopiperazin-1-yl]methyl}-1H-imidazol-1-yl)methyl]benzonitrile …
Nesbuvir
Nesbuvir has been investigated for the treatment of Hepatitis C.
Investigational
Matched Iupac: … 5-cyclopropyl-2-(4-fluorophenyl)-6-[N-(2-hydroxyethyl)methanesulfonamido]-N-methyl-1-benzofuran-3-carboxamide …
Etozoline
Etozoline is marketed in Europe under the names Diulozin, Elkapin, and Etopinil. Etozoline is a loop diuretic.
Experimental
Matched Iupac: … ethyl 2-[(2Z)-3-methyl-4-oxo-5-(piperidin-1-yl)-1,3-thiazolidin-2-ylidene]acetate …
SCH-900271
Sch 900271 has been used in trials studying the treatment of Mixed Hyperlipidemia and Primary Hypercholesterolemia.
Investigational
Matched Iupac: … 5-[3-(1-methylcyclopropyl)propyl]-1H,2H,3H,4H,7H-pyrano[2,3-d]pyrimidine-2,4,7-trione …
Aleplasinin
Aleplasinin has been investigated in Alzheimer Disease.
Investigational
Matched Iupac: … 2-{1-[(4-tert-butylphenyl)methyl]-5-(3-methylphenyl)-1H-indol-3-yl}-2-oxoacetic acid …
Piprozolin
Experimental
Matched Iupac: … ethyl 2-[(2Z)-3-ethyl-4-oxo-5-(piperidin-1-yl)-1,3-thiazolidin-2-ylidene]acetate …
Englitazone
Englitazone is a hypoglycemic agent.
Experimental
Matched Iupac: … 5-{[(2R)-2-benzyl-3,4-dihydro-2H-1-benzopyran-6-yl]methyl}-1,3-thiazolidine-2,4-dione …
Branaplam
Branaplam is under investigation in clinical trial NCT02268552 (An Open Label Study of LMI070 (Branaplam) in Type 1 Spinal Muscular Atrophy (SMA)).
Investigational
Matched Iupac: … 5-(1H-pyrazol-4-yl)-2-{6-[(2,2,6,6-tetramethylpiperidin-4-yl)oxy]pyridazin-3-yl}phenol …
Enarodustat
Enarodustat is under investigation in clinical trial NCT02581124 (Study to Evaluate Effect of Lapatinib on Pharmacokinetics of JTZ-951 in Subjects With End-stage Renal Disease).
Investigational
Matched Iupac: … 2-{[7-hydroxy-5-(2-phenylethyl)-[1,2,4]triazolo[1,5-a]pyridin-8-yl]formamido}acetic acid …
Morinidazole
Morinidazole is under investigation in clinical trial NCT03380793 (A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis).
Investigational
Matched Iupac: … 1-(2-methyl-5-nitro-1H-imidazol-1-yl)-3-(morpholin-4-yl)propan-2-ol …
Esaxerenone
Esaxerenone is under investigation in clinical trial NCT02722265 (Long-term Study of CS-3150 as Monotherapy or in Combination With Other Antihypertensive Drug in Japanese Patients With Essential Hypertension).
Investigational
Matched Iupac: … 1-(2-hydroxyethyl)-N-(4-methanesulfonylphenyl)-4-methyl-5-[2-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide …
JPC-3210
JPC-3210 is a potent antimalarial agent. It is an erythrocytic schizonticide with potent in vitro antimalarial activity against multidrug-resistant Plasmodium falciparum lines, low cytotoxicity, potent in vivo efficacy against murine malaria, and favourable preclinical pharmacokinetics including a lengthy plasma elimination half-life.
Experimental
Matched Iupac: … 4-tert-butyl-2-[(tert-butylamino)methyl]-6-[5-fluoro-6-(trifluoromethyl)pyridin-3-yl]phenol …
Rovazolac
Rovazolac is under investigation in clinical trial NCT03175354 (A Study in Subjects With Moderate Atopic Dermatitis).
Investigational
Matched Iupac: … ethyl 2-(5-{3'-methanesulfonyl-[1,1'-biphenyl]-4-yl}-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetate …
Cinchonidine
Investigational
Matched Iupac: … (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](quinolin-4-yl)methanol …
CRA-9334
Experimental
Matched Iupac: … 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2-yl}-6-bromo-4-methylbenzen-1-olate …
Methylthioinosine
An analog of inosine with a methylthio group replacing the hydroxyl group in the 6-position.
Experimental
Matched Iupac: … (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methylsulfanyl)-9H-purin-9-yl]oxolane-3,4-diol …
BIA
Experimental
Matched Iupac: … 1-(3,4-dihydroxy-5-nitrophenyl)-3-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}propan-1-one …
2-(acetylamino)-2-deoxy-4-O-sulfo-alpha-D-galactopyranose
Experimental
Matched Iupac: … [(2R,3R,4R,5R,6S)-5-acetamido-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxidanesulfonic acid …
Voglibose
Voglibose is an alpha-glucosidase inhibitor used for lowering post-prandial blood glucose levels in people with diabetes mellitus. It is made in India by Ranbaxy Labs and sold under the trade name Volix.
Investigational
Matched Iupac: … (1S,2S,3R,4S,5S)-5-[(1,3-dihydroxypropan-2-yl)amino]-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol …
Laquinimod
Laquinimod is an immunomodulator developed by Active Biotech and produced by Teva Pharmaceutical Industries. It is currently under development in phase III trials for treatment of multiple sclerosis as an oral therapy, like fingolimod. It has been shown to reduce disease activity on magnetic resonance imaging and to be well...
Investigational
Matched Iupac: … 5-chloro-N-ethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide …
(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine
Experimental
Matched Iupac: … (11R,12R)-5-methanesulfonyl-11-(2,4,5-trifluorophenyl)-1,8-diazatricyclo[7.4.0.0^{2,7}]trideca-2,4,6,8 …
PNU-142721
Experimental
Matched Iupac: … 6-chloro-2-{[(1S)-1-{furo[2,3-c]pyridin-5-yl}ethyl]sulfanyl}pyrimidin-4-amine …
Displaying drugs 6601 - 6625 of 7440 in total