Displaying drugs 6601 - 6625 of 10792 in total
Rheinanthrone
Rheinanthrone is the active metabolite of senna glycoside DB11365 known for its laxative effect . It is commonly produced by plants of the Rheum species .
Experimental
Matched Iupac: … 4,5-dihydroxy-10-oxo-9,10-dihydroanthracene-2-carboxylic acid …
Rhein
Rhein is an anthraquinone metabolite of rheinanthrone and senna glycoside is present in many medicinal plants including Rheum palmatum, Cassia tora, Polygonum multiflorum, and Aloe barbadensis . It is known to have hepatoprotective, nephroprotective, anti-cancer, anti-inflammatory, and several other protective effects.
Experimental
Matched Iupac: … 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid …
LGD-3303
An androgen receptor modulator.
Experimental
Matched Synonyms: … 9-Chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H-pyrrolo(3,2-F)quinolin-7(6H)-one …
Matched Iupac: … 9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H,6H,7H-pyrrolo[3,2-f]quinolin-7-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H,6H,7H-pyrrolo[3,2-f]quinolin-7-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Z-160
Z160 has been used in trials studying the treatment of Postherpetic Neuralgia and Lumbosacral Radiculopathy.
Investigational
Matched Synonyms: … 1-(4-Benzhydryl-piperazin-1-yl)-3,3-diphenylpropan-1-one ... 1-(4-Benzhydrylpiperazin-1-yl)-3,3-Diphenylpropan-1-one …
Matched Iupac: … 1-[4-(diphenylmethyl)piperazin-1-yl]-3,3-diphenylpropan-1-one …
Matched Iupac: … 1-[4-(diphenylmethyl)piperazin-1-yl]-3,3-diphenylpropan-1-one …
Isoamyl alcohol
Experimental
Matched Synonyms: … 2-methyl-4-butanol ... 3-Methylbutanol ... 3-methyl-1-butanol …
Matched Iupac: … 3-methylbutan-1-ol …
Matched Iupac: … 3-methylbutan-1-ol …
Epicillin
Experimental
Matched Iupac: … [3.2.0]heptane-2-carboxylic acid ... (2S,5R,6R)-6-[(2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
6-[2-(3'-METHOXYBIPHENYL-3-YL)ETHYL]PYRIDIN-2-AMINE
Experimental
Matched Name: … 6-[2-(3'-METHOXYBIPHENYL-3-YL)ETHYL]PYRIDIN-2-AMINE …
Matched Iupac: … 6-(2-{3'-methoxy-[1,1'-biphenyl]-3-yl}ethyl)pyridin-2-amine …
Matched Iupac: … 6-(2-{3'-methoxy-[1,1'-biphenyl]-3-yl}ethyl)pyridin-2-amine …
LY-294002
Specific inhibitor of phosphatidylinositol 3-kinase.
Experimental
Matched Synonyms: … 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one …
Matched Iupac: … 2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one …
Matched Description: … Specific inhibitor of phosphatidylinositol 3-kinase. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Matched Iupac: … 2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one …
Matched Description: … Specific inhibitor of phosphatidylinositol 3-kinase. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
SB-269970
SB-269970 is an experimental drug developed by GlaxoSmithKline. In the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 (5-HT7).[A31816,A31817]
Investigational
Matched Iupac: … 3-{[(2R)-2-[2-(4-methylpiperidin-1-yl)ethyl]pyrrolidin-1-yl]sulfonyl}phenol …
Matched Description: … that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 (5- …
Matched Description: … that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 (5- …
6S-5,6,7,8-Tetrahydrobiopterin
Experimental
Matched Iupac: … (6R)-2-amino-6-[(1S,2R)-1,2-dihydroxypropyl]-1,4,5,6,7,8-hexahydropteridin-4-one …
5,10-Methylene-6-Hydrofolic Acid
Experimental
Matched Iupac: … (2R)-2-({4-[(6aS)-3-amino-1-oxo-1H,4H,6aH,7H,8H,9H-imidazo[1,5-f]pteridin-8-yl]phenyl}formamido)pentanedioic …
Imazaquin
Experimental
Matched Iupac: … 2-[(4R)-4-methyl-5-oxo-4-(propan-2-yl)-4,5-dihydro-1H-imidazol-2-yl]quinoline-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Trinitrotoluene
Trinitrotoluene is an explosive chemical that can cause skin irritation and other toxic consequences.
Experimental
Matched Iupac: … 2-methyl-1,3,5-trinitrobenzene …
Pyrroloquinoline Quinone
A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES. [PubChem]
Experimental
Matched Iupac: … 4,5-dioxo-1H,4H,5H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid …
Matched Description: … A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
S-Nitrosoglutathione
Investigational
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-(nitrososulfanyl)ethyl]carbamoyl}butanoic acid …
N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE
Experimental
Matched Name: … N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE …
Matched Iupac: … (1r,4r)-N-{2'-[(4-fluorophenyl)amino]-[4,4'-bipyridin]-2-yl}-4-methoxycyclohexane-1-carboxamide …
Matched Iupac: … (1r,4r)-N-{2'-[(4-fluorophenyl)amino]-[4,4'-bipyridin]-2-yl}-4-methoxycyclohexane-1-carboxamide …
4-({[4-(3-METHYLBENZOYL)PYRIDIN-2-YL]AMINO}METHYL)BENZENECARBOXIMIDAMIDE
Experimental
Matched Name: … 4-({[4-(3-METHYLBENZOYL)PYRIDIN-2-YL]AMINO}METHYL)BENZENECARBOXIMIDAMIDE …
Matched Iupac: … 4-({[4-(3-methylbenzoyl)pyridin-2-yl]amino}methyl)benzene-1-carboximidamide …
Matched Iupac: … 4-({[4-(3-methylbenzoyl)pyridin-2-yl]amino}methyl)benzene-1-carboximidamide …
Pravibismane
Investigational
Matched Synonyms: … 1,2-bis((1,3-dithia-2-bismolan-2-yl)thio)ethane ... 1,2-bis((1,3-dithia-2-bismolane-2-yl)thio)ethane ... 1,2-(bis(1,3-dithia-2-bismolane)thio)ethane …
Matched Iupac: … 2-{[2-(1,3-dithia-2-bismacyclopentan-2-ylsulfanyl)ethyl]sulfanyl}-1,3-dithia-2-bismacyclopentane …
Matched Iupac: … 2-{[2-(1,3-dithia-2-bismacyclopentan-2-ylsulfanyl)ethyl]sulfanyl}-1,3-dithia-2-bismacyclopentane …
Metenkefalin
Metenkefalin is an endogenous opioid and beta-endorphin. It has been shown to reduce chromosomal abberations in patients with multiple sclerosis. Metenkefalin, along with tridecactide, are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]
Investigational
Matched Iupac: … (2S)-2-[(2S)-2-(2-{2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]acetamido}acetamido)-3-phenylpropanamido ... ]-4-(methylsulfanyl)butanoic acid …
Matched Salts cas: … 82362-17-2 …
Matched Salts cas: … 82362-17-2 …
Itepekimab
Itepekimab is under investigation in clinical trial NCT03546907 (Proof-of-concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-il-33 Mab) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)).
Investigational
Matched Synonyms: … Immunoglobulin igg4 (230-proline), anti-(human interleukin 33) (human monoclonal regn3500 .gamma.4-chain …
2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile
Experimental
Matched Name: … 2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene ... ]amino}-3-methylbenzonitrile …
Matched Iupac: … 2-chloro-3-methylbenzonitrile ... 4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)-hexahydropyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}- …
Matched Iupac: … 2-chloro-3-methylbenzonitrile ... 4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)-hexahydropyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}- …
1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-one
Experimental
Matched Name: … 1-{3-oxo-3-[(2S)-2-(pyrrolidin-1-ylcarbonyl)pyrrolidin-1-yl]propyl}-3-phenylquinoxalin-2(1H)-one …
Matched Iupac: … 1-{3-oxo-3-[(2S)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]propyl}-3-phenyl-1,2-dihydroquinoxalin-2-one …
Matched Iupac: … 1-{3-oxo-3-[(2S)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]propyl}-3-phenyl-1,2-dihydroquinoxalin-2-one …
BN-201
Investigational
Matched Synonyms: … N-(2-amino-2-oxoethyl)-2-(2-((4-fluorophenethyl)amino)-N-isobutylacetamido)-N-(3-(2-oxopyrrolidin-1-yl ... Glycinamide, n-(2-(2-fluorophenyl)ethyl)glycyl-n-(2-methylpropyl)glycyl-n2-(3-(2-oxo-1-pyrrolidinyl)propyl ... )propyl)acetamide N-({Carbamoylmethyl-[3-(2-oxo-pyrrolidin-1-yl)propyl}-carbamoyl}-methyl)-2-[2-(2-fluorophenyl …
Matched Iupac: … N-(carbamoylmethyl)-2-(2-{[2-(2-fluorophenyl)ethyl]amino}-N-(2-methylpropyl)acetamido)-N-[3-(2-oxopyrrolidin …
Matched Iupac: … N-(carbamoylmethyl)-2-(2-{[2-(2-fluorophenyl)ethyl]amino}-N-(2-methylpropyl)acetamido)-N-[3-(2-oxopyrrolidin …
Isatoribine
Isatoribine is a selective agonist of TLR7.
Investigational
Matched Iupac: … 5-amino-3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2H,3H,4H,7H-[1,3]thiazolo[4,5-d] …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 6601 - 6625 of 10792 in total