Displaying drugs 6676 - 6700 of 7686 in total
Sacubitrilat
A metabolite of LCZ696 with neprilysin inhibitory activity.
Experimental
Matched Iupac: … (2R,4S)-5-{[1,1'-biphenyl]-4-yl}-4-(3-carboxypropanamido)-2-methylpentanoic acid …
AN2898
AN2898 is under investigation in clinical trial NCT01301508 (Efficacy and Safety of AN2898 and AN2728 Topical Ointments to Treat Mild-to-moderate Atopic Dermatitis).
Investigational
Matched Iupac: … 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzene-1,2-dicarbonitrile …
L-Histidine Beta Naphthylamide
Experimental
Matched Iupac: … (2R)-2-amino-3-(1H-imidazol-5-yl)-N-(naphthalen-2-yl)propanamide …
CRA_8696
Experimental
Matched Iupac: … 3-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-[1,1'-biphenyl]-2-olate …
Monastrol
Experimental
Matched Iupac: … ethyl (4S)-4-(3-hydroxyphenyl)-6-methyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxylate …
Propentofylline
Investigational
Matched Iupac: … 3-methyl-1-(5-oxohexyl)-7-propyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Tymazoline
Tymazoline is a nasal preparation.
Experimental
Matched Iupac: … 2-{[5-methyl-2-(propan-2-yl)phenoxy]methyl}-4,5-dihydro-1H-imidazole …
Netoglitazone
Netoglitazone (MCC-555) is a hypoglycemic agent.
Experimental
Matched Iupac: … 5-({6-[(2-fluorophenyl)methoxy]naphthalen-2-yl}methyl)-1,3-thiazolidine-2,4-dione …
Cerlapirdine
Cerlapirdine has been investigated for the treatment of Alzheimer Disease.
Investigational
Matched Iupac: … dimethyl(3-{[3-(naphthalene-1-sulfonyl)-1H-indazol-5-yl]oxy}propyl)amine …
NB-001
NB-001 has been investigated for the treatment of Recurrent Herpes Labialis.
Investigational
Matched Iupac: … 5-{[2-(6-amino-9H-purin-9-yl)ethyl]amino}pentan-1-ol …
IOWH-032
Iowh032 has been investigated for the treatment of Cholera, Diarrhea, and Secretory Diarrhea.
Investigational
Matched Iupac: … 3-(3,5-dibromo-4-hydroxyphenyl)-N-[(4-phenoxyphenyl)methyl]-1,2,4-oxadiazole-5-carboxamide …
Nimustine
Nimustine has been used in trials studying the treatment of Glioblastoma.
Investigational
Matched Iupac: … 1-[(4-amino-2-methylpyrimidin-5-yl)methyl]-3-(2-chloroethyl)-3-nitrosourea …
Nifurtoinol
Experimental
Matched Iupac: … 3-(hydroxymethyl)-1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione …
Furafylline
Furafylline is a derivative of methylxanthine derivative. It was developed on the context of asthma as a long-acting alternative for theophylline.
Experimental
Matched Iupac: … 4-(5-{7-azabicyclo[2.2.1]heptan-2-yl}-2-fluoropyridin-3-yl)benzonitrile …
Macelignan
Macelignan is an NSAID with antioxidant, free radical scavenging, and neuroprotective activities.
Experimental
Matched Iupac: … 4-[(2S,3R)-4-(2H-1,3-benzodioxol-5-yl)-2,3-dimethylbutyl]-2-methoxyphenol …
IQP-0528
IQP-0528 is under investigation in clinical trial NCT03082690 (ImQuest (IQP) DuoGel Phase 1 Pharmacokinetic Study).
Investigational
Matched Iupac: … 1-(cyclopropylmethyl)-6-(3,5-dimethylbenzoyl)-5-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Dirocaftor
Dirocaftor is under investigation in clinical trial NCT03251092 (Study Designed to Assess the Safety, Tolerability and PK of PTI-808 in Healthy Volunteers and in Adults With Cystic Fibrosis).
Investigational
Matched Iupac: … N-[5-hydroxy-2,4-bis(trimethylsilyl)phenyl]-4-oxo-1,4-dihydroquinoline-3-carboxamide …
Olodanrigan
Olodanrigan is under investigation in clinical trial NCT03297294 (Safety and Efficacy of EMA401 in Patients With Painful Diabetic Neuropathy (PDN)).
Investigational
Matched Iupac: … (3S)-5-(benzyloxy)-2-(2,2-diphenylacetyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid …
Tallimustine
Tallimustine, a benzoyl mustard derivative of distamycin A, is an alkylating agent that binds to the minor groove of DNA.[A182036,A182039] It's association with severe myelotoxicity lead to the end of its development in favour of α-halogenoacrylamide derivatives such as brostallicin, which have a favourable cytotoxicity/myelotoxicity ratio.[A182039,A182045] Newer generations of DNA...
Experimental
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]benzamido}-N-[5-({5-[(2-carbamimidoylethyl)carbamoyl]-1-methyl-1H-pyrrol …
Etonitazene
Experimental
Illicit
Matched Iupac: … (2-{2-[(4-ethoxyphenyl)methyl]-5-nitro-1H-1,3-benzodiazol-1-yl}ethyl)diethylamine …
N-acetyl-beta-D-galactosamine 6-sulfate
Experimental
Matched Iupac: … {[(2R,3R,4R,5R,6R)-5-acetamido-3,4,6-trihydroxyoxan-2-yl]methoxy}sulfonic acid …
Iodo-Willardiine
Experimental
Matched Iupac: … (2S)-2-amino-3-(5-iodo-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid …
Fluoro-Willardiine
Experimental
Matched Iupac: … (2S)-2-amino-3-(5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)propanoic acid …
Tetrahydrodeoxyuridine
Experimental
Matched Iupac: … 1-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione …
Nebularine
Experimental
Matched Iupac: … (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(9H-purin-9-yl)oxolane-3,4-diol …
Displaying drugs 6676 - 6700 of 7686 in total