Displaying drugs 651 - 675 of 4242 in total
Nalidixic acid
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched International brands: … Nal-acid …
Matched Synonyms: … 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid ... 1-ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carboxylic acid ... 1-Ethyl-7-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid …
Matched Name: … Nalidixic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum …
Matched Categories: … nalidixic acid …
Matched Products: … ACIDO NALIDIXICO ... ACIDO NALIDIXICO NOVASOREL ... ACIDO NALIDIXICO SUSPENSION …
Matched Synonyms: … 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid ... 1-ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carboxylic acid ... 1-Ethyl-7-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid …
Matched Name: … Nalidixic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum …
Matched Categories: … nalidixic acid …
Matched Products: … ACIDO NALIDIXICO ... ACIDO NALIDIXICO NOVASOREL ... ACIDO NALIDIXICO SUSPENSION …
(Rp)-cAMPS
Experimental
Matched Synonyms: … (Rp)-adenosine-3',5'-cyclic monophosphorothioate ... adenosine-3',5'-cyclic monophosphorothioate, Rp-isomer …
Matched Iupac: … (2R,4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-sulfanyl-hexahydro-2lambda5-furo[3,2-d][1,3,2 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Adenine Nucleotides …
Matched Iupac: … (2R,4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-sulfanyl-hexahydro-2lambda5-furo[3,2-d][1,3,2 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Adenine Nucleotides …
Cotton seed
Cotton seed allergenic extract is used in allergenic testing.
Approved
Matched Name: … Cotton seed …
Matched Description: … Cotton seed allergenic extract is used in allergenic testing. …
Matched Products: … Cotton Seed ... Cotton Seed for Diagnostic Use Only …
Matched Description: … Cotton seed allergenic extract is used in allergenic testing. …
Matched Products: … Cotton Seed ... Cotton Seed for Diagnostic Use Only …
American chestnut
American chestnut allergenic extract is used in allergenic testing.
Approved
Matched Name: … American chestnut …
Matched Description: … American chestnut allergenic extract is used in allergenic testing. …
Matched Description: … American chestnut allergenic extract is used in allergenic testing. …
Juniperus monosperma pollen
Juniperus monosperma pollen is the pollen of the Juniperus monosperma plant. Juniperus monosperma pollen is mainly used in allergenic testing.
Approved
Matched Products: … One Seed Juniper ... One Seed Juniper Pollen …
Glutamic acid
A peptide that is a homopolymer of glutamic acid.
Approved
Nutraceutical
Matched Synonyms: … L-Glutamic acid ... L-Glutaminic acid ... L-Glutamate …
Matched Name: … Glutamic acid …
Matched Iupac: … (2S)-2-aminopentanedioic acid …
Matched Description: … A peptide that is a homopolymer of glutamic acid. …
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Salts name: … Glutamic acid hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids ... Acid Preparations …
Matched Products: … Glutamic Acid HCl Cap 325mg …
Matched Name: … Glutamic acid …
Matched Iupac: … (2S)-2-aminopentanedioic acid …
Matched Description: … A peptide that is a homopolymer of glutamic acid. …
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Aminosyn II and Dextrose ... Aminosyn II and Dextrose …
Matched Salts name: … Glutamic acid hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids ... Acid Preparations …
Matched Products: … Glutamic Acid HCl Cap 325mg …
Isoglutamine
Experimental
Matched Synonyms: … L-Glutamic acid alpha-amide ... Glutamic acid alpha-amide ... L-Isoglutamine …
Matched Iupac: … (4S)-4-amino-4-carbamoylbutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino ... Amino Acids, Neutral …
Matched Iupac: … (4S)-4-amino-4-carbamoylbutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino ... Amino Acids, Neutral …
Sesame oil
Sesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic acid, stearic acid and other fatty acids. Sesame oil is reported to possess antioxidant, antiaging, antihypertensive, immunoregulatory and anticancer properties....
Investigational
Nutraceutical
Matched Synonyms: … Zhi ma seed oil ... Sesamum indicum seed oil ... Sesamum orientale seed oil …
Matched Description: … It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic acid, stearic acid ... and other fatty acids. ... Sesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices …
Matched Categories: … Diet, Food, and Nutrition …
Matched Description: … It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic acid, stearic acid ... and other fatty acids. ... Sesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices …
Matched Categories: … Diet, Food, and Nutrition …
Obinepitide
Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS. In obinepitide,...
Investigational
Matched Synonyms: … (34-L-glutamine)pancreatic hormone (human) …
Matched Iupac: … methylsulfanyl)propyl]-C-hydroxycarbonimidoyl}-3-(C-hydroxycarbonimidoyl)propyl]-C-hydroxycarbonimidoyl}butanoic acid …
Matched Description: … Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which ... These hormones are known to play a role in the regulation of food intake and appetite in man as satiety …
Matched Iupac: … methylsulfanyl)propyl]-C-hydroxycarbonimidoyl}-3-(C-hydroxycarbonimidoyl)propyl]-C-hydroxycarbonimidoyl}butanoic acid …
Matched Description: … Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which ... These hormones are known to play a role in the regulation of food intake and appetite in man as satiety …
Red pepper
Red pepper allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Cayenne pepper seed ... Capsicum annuum var. annuum seed …
L-2,4-diaminobutyric acid
Experimental
Matched Synonyms: … L-diaminobutyric acid ... L-2,4-diaminobutanoic acid ... (S)-2,4-Diaminobutanoic acid …
Matched Name: … L-2,4-diaminobutyric acid …
Matched Iupac: … (2S)-2,4-diaminobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Name: … L-2,4-diaminobutyric acid …
Matched Iupac: … (2S)-2,4-diaminobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Dehydroascorbic acid
Dehydroascorbic acid is made from the oxidation of ascorbic acid. This reaction is reversible, but dehydroascorbic acid can instead undergo irreversible hydrolysis to 2,3-diketogulonic acid. Dehydroascorbic acid as well as ascorbic acid are both termed Vitamin C, but the latter is the main form found in humans. In the body,...
Experimental
Matched Synonyms: … dehydro-L-ascorbic acid ... L-dehydroascorbic acid ... L-threo-2,3-hexodiulosonic acid, γ-lactone …
Matched Name: … Dehydroascorbic acid …
Matched Description: … In the body, both dehydroascorbic acid and ascorbic acid have similar biological activity as antivirals ... found in humans. ... Dehydroascorbic acid is made from the oxidation of ascorbic acid. …
Matched Categories: … Diet, Food, and Nutrition ... Vitamin C and analogues ... Acids, Acyclic ... Sugar Acids ... Hydroxy Acids …
Matched Name: … Dehydroascorbic acid …
Matched Description: … In the body, both dehydroascorbic acid and ascorbic acid have similar biological activity as antivirals ... found in humans. ... Dehydroascorbic acid is made from the oxidation of ascorbic acid. …
Matched Categories: … Diet, Food, and Nutrition ... Vitamin C and analogues ... Acids, Acyclic ... Sugar Acids ... Hydroxy Acids …
Coral snake (micrurus fulvius) immune globulin antivenin (equine)
North American Coral Snake Antivenin (Equine) is a horse-derived antivenin indicated for the treatment of envenomation caused by North American coral snake bites. It is intravenously administered so that the antivenin binds to and neutralizes coral snake venom.
The antivenin is a refined, concentrated, and lyophilized preparation of serum globulins...
Approved
Experimental
Matched Synonyms: … North American coral snake antivenin ... North American Coral Snake Antivenin (Equine) ... North american coral snake (micrurus fulvius) antivenin (equine) …
Matched Description: … It is intravenously administered so that the antivenin binds to and neutralizes coral snake venom. ... The antivenin is a refined, concentrated, and lyophilized preparation of serum globulins obtained by ... Prior to lyophilization, the product contains 0.25% phenol and 0.005% thiomerosal (mercury derivative …
Matched Products: … North American Coral Snake Antivenin (Equine) …
Matched Description: … It is intravenously administered so that the antivenin binds to and neutralizes coral snake venom. ... The antivenin is a refined, concentrated, and lyophilized preparation of serum globulins obtained by ... Prior to lyophilization, the product contains 0.25% phenol and 0.005% thiomerosal (mercury derivative …
Matched Products: … North American Coral Snake Antivenin (Equine) …
Binodenoson
Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor. This specificity allows Binodenoson to deliver - in a single injection - a more effective dose of medication with fewer side effects than current treatments, which typically require a...
Investigational
Matched Synonyms: … 2-((Cyclohexylmethylene)hydrazino)adenosine …
Matched Description: … Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Gadopentetic acid
A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
Approved
Matched Synonyms: … Acide gadopentetique ... Gadopentetic acid ... Acidum gadopenteticum …
Matched Name: … Gadopentetic acid …
Matched Description: … acid), that is given to enhance the image in cranial and spinal MRIs. ... A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic …
Matched Salts cas: … 86050-77-3 …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... gadopentetic acid …
Matched Products: … Magnevist 2 mmol/l - Injektionslösung ... ACIDO GADOPENTETICO SANOCHEMIA PHARMAZEUTIKA …
Matched Name: … Gadopentetic acid …
Matched Description: … acid), that is given to enhance the image in cranial and spinal MRIs. ... A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic …
Matched Salts cas: … 86050-77-3 …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... gadopentetic acid …
Matched Products: … Magnevist 2 mmol/l - Injektionslösung ... ACIDO GADOPENTETICO SANOCHEMIA PHARMAZEUTIKA …
Panax quinquefolius whole
Panax quinquefolius whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Synonyms: … American Ginseng ... American Ginseng Whole …
Cholecalciferol
Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are...
Approved
Nutraceutical
Matched Synonyms: … Activated 7-dehydrocholesterol ... (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol ... (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol …
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene …
Matched Description: … C23 and has an additional methyl group at C24 [L5689]. ... forms of vitamin d and are found in various types of food for daily intake [L5689]. ... D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are considered the main …
Matched Mixtures name: … Port A Mins Super Calcium 750 With Vitamin D3 ... Cod Liver Oil USP ... Cod Liver Oil Cap …
Matched Categories: … ibandronic acid and colecalciferol ... risedronic acid and colecalciferol ... alendronic acid and colecalciferol ... zoledronic acid, calcium and colecalciferol, sequential ... alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … L-VIT D3 5000 ... Live-well™ Vitamin D3-400IU Capsule ... Live-Well® SUNSHINE VITAMIN-D3 Tablet …
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene …
Matched Description: … C23 and has an additional methyl group at C24 [L5689]. ... forms of vitamin d and are found in various types of food for daily intake [L5689]. ... D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalciferol), are considered the main …
Matched Mixtures name: … Port A Mins Super Calcium 750 With Vitamin D3 ... Cod Liver Oil USP ... Cod Liver Oil Cap …
Matched Categories: … ibandronic acid and colecalciferol ... risedronic acid and colecalciferol ... alendronic acid and colecalciferol ... zoledronic acid, calcium and colecalciferol, sequential ... alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … L-VIT D3 5000 ... Live-well™ Vitamin D3-400IU Capsule ... Live-Well® SUNSHINE VITAMIN-D3 Tablet …
Unoprostone
Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate.
The main indication of Unoprostane is treatment of glucoma.
Approved
Investigational
Matched Synonyms: … 13,14-dihydro-15-keto-20-ethyl PGF2α …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]hept-5-enoic acid …
Matched Description: … Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Fatty Acids ... Fatty Acids, Unsaturated …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]hept-5-enoic acid …
Matched Description: … Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Fatty Acids ... Fatty Acids, Unsaturated …
Spaglumic acid
Spaglumic acid is the β-aspartyl isoform of N-Acetyl-l-aspartylglutamate (isospaglumic Acid is N-(N-Acetyl-l-α-aspartyl)-l-glutamic acid). In eye drops, spaglumic acid is either a magnesium or sodium salt of N-Acetyl-l-aspartylglutamate. Spaglumic acid is a mast cell stabilizer. Thus it is used in allergic conditions such as allergic conjunctivitis. Specifically spaglumic acid is approved...
Experimental
Matched Synonyms: … N-Acetyl-L-β-aspartyl-L-glutamic acid ... Spaglumic acid …
Matched Name: … Spaglumic acid …
Matched Iupac: … (2S)-2-[(3S)-3-carboxy-3-acetamidopropanamido]pentanedioic acid …
Matched Description: … Specifically spaglumic acid is approved in Portugal under the brand name Naabak and in Greece under the ... )-l-glutamic acid). ... Spaglumic acid is the β-aspartyl isoform of N-Acetyl-l-aspartylglutamate (isospaglumic Acid is N-(N-Acetyl-l-α-aspartyl …
Matched Categories: … Decongestants and Antiallergics ... spaglumic acid ... spaglumic acid …
Matched Name: … Spaglumic acid …
Matched Iupac: … (2S)-2-[(3S)-3-carboxy-3-acetamidopropanamido]pentanedioic acid …
Matched Description: … Specifically spaglumic acid is approved in Portugal under the brand name Naabak and in Greece under the ... )-l-glutamic acid). ... Spaglumic acid is the β-aspartyl isoform of N-Acetyl-l-aspartylglutamate (isospaglumic Acid is N-(N-Acetyl-l-α-aspartyl …
Matched Categories: … Decongestants and Antiallergics ... spaglumic acid ... spaglumic acid …
Histrelin
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched International brands: … Supprelin LA …
Matched Synonyms: … [(im-Bzl)-D-His6,Pro9-NEt]-gonadotropin releasing hormone ... 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide ... 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-Nτ-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide …
Matched Iupac: … propanamido]-4-methylpentanamido]-5-carbamimidamidopentanoyl]-N-ethylpyrrolidine-2-carboxamide; bis(acetic acid …
Matched Description: … levels and the concentration of sex steroids. ... Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin ... As the product Supprelin LA, histrelin is indicated for the treatment of CPP in children (approved by …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hypothalamic Hormones ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Supprelin LA …
Matched Synonyms: … [(im-Bzl)-D-His6,Pro9-NEt]-gonadotropin releasing hormone ... 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide ... 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-Nτ-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide …
Matched Iupac: … propanamido]-4-methylpentanamido]-5-carbamimidamidopentanoyl]-N-ethylpyrrolidine-2-carboxamide; bis(acetic acid …
Matched Description: … levels and the concentration of sex steroids. ... Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin ... As the product Supprelin LA, histrelin is indicated for the treatment of CPP in children (approved by …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hypothalamic Hormones ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Supprelin LA …
White mustard seed
White mustard seed allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Bai jie seed ... Brassica alba seed ... Brassica hirta seed …
Matched Name: … White mustard seed …
Matched Description: … White mustard seed allergenic extract is used in allergenic testing. …
Matched Name: … White mustard seed …
Matched Description: … White mustard seed allergenic extract is used in allergenic testing. …
Adenosine 3',5'-diphosphate
Experimental
Matched Synonyms: … Adenosine 3',5'-bismonophosphate ... Adenosine 3'-phosphate-5'-phosphate …
Matched Name: … Adenosine 3',5'-diphosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Adenine Nucleotides …
Matched Name: … Adenosine 3',5'-diphosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}phosphonic acid …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Adenine Nucleotides …
Displaying drugs 651 - 675 of 4242 in total