Displaying drugs 651 - 675 of 1983 in total
ANEB-001
ANEB-001 is under investigation in clinical trial NCT05282797 (Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CB1 Antagonist ANEB-001 in a THC Challenge Test).
Investigational
Matched Synonyms: … 1-AZETIDINECARBOXAMIDE, 3-((R)-(4-CHLOROPHENYL)(2-(TRIFLUOROMETHYL)PHENYL)METHOXY)-N-(1,1-DIMETHYLETHYL ... 3-((R)-(4-CHLOROPHENYL)(2-(TRIFLUOROMETHYL)PHENYL)METHOXY)-N-(1,1-DIMETHYLETHYL)-1-AZETIDINECARBOXAMIDE …
Matched Description: … ANEB-001 is under investigation in clinical trial NCT05282797 (Safety, Tolerability, Pharmacokinetics, and …
Matched Description: … ANEB-001 is under investigation in clinical trial NCT05282797 (Safety, Tolerability, Pharmacokinetics, and …
Ceritinib
Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of prior crizotinib therapy. About 4% of patients with NSCLC have a chromosomal rearrangement that generates a fusion gene between EML4 (echinoderm microtubule-associated protein-like...
Approved
Matched Synonyms: … N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl} …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine …
Matched Description: … Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic ... lymphoma kinase), which results in constitutive kinase activity that contributes to carcinogenesis and ... autophosphorylation of ALK, ALK-mediated phosphorylation of the downstream signaling protein STAT3, and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Erythromycin
Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of Azithromycin, Clarithromycin, Spiramycin and others. It was originally discovered in 1952. Erythromycin is widely used for treating a variety of infections, including those...
Approved
Investigational
Vet approved
Matched Description: … [L5245,L7261] It is available for administration in various forms, including intravenous, topical, and ... and gram-negative bacteria. ... antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and …
Matched Mixtures name: … Stievamycin Forte ... Erythromycin and Benzoyl Peroxide ... Erythromycin and Benzoyl Peroxide …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins ... Protein Synthesis Inhibitors ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … ERYRA FORTE ... AKELA FORTE % 4 JEL, 30 GRAM ... ETTROCIN FOR SUSPENSION 200MG/5ML …
Matched Mixtures name: … Stievamycin Forte ... Erythromycin and Benzoyl Peroxide ... Erythromycin and Benzoyl Peroxide …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins ... Protein Synthesis Inhibitors ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … ERYRA FORTE ... AKELA FORTE % 4 JEL, 30 GRAM ... ETTROCIN FOR SUSPENSION 200MG/5ML …
Strimvelis
Investigational
Matched Synonyms: … CD34+ enriched cell fraction that contains CD34+ cells transduced with retroviral vector that encodes for …
Sotatercept
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER ... ACTIVIN RECEPTOR TYPE IIA (SYNTHETIC HUMAN EXTRACELLULAR DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... [L50351] On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... [L50351] On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cycrimine
Cycrimine is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and management of Parkinson's disease.
Approved
Matched Synonyms: … alpha-cyclopentyl-alpha-phenyl-1-piperidinepropanol …
Matched Iupac: … 1-cyclopentyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Description: … is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and …
Matched Iupac: … 1-cyclopentyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Description: … is a drug used to reduce levels of acetylcholine to return a balance with dopamine in the treatment and …
Furaprofen
Investigational
Matched Synonyms: … alpha-Methyl-3-phenyl-7-benzofuranacetic acid …
Matched Iupac: … 2-(3-phenyl-1-benzofuran-7-yl)propanoic acid …
Matched Iupac: … 2-(3-phenyl-1-benzofuran-7-yl)propanoic acid …
TG100-115
An NSAID that inhibits PI-3K gamma and delta.
Investigational
Matched Synonyms: … 3-(2,4-Diamino-6-(3-hydroxyphenyl)pteridin-7-yl)phenol …
Matched Iupac: … 3-[2,4-diamino-7-(3-hydroxyphenyl)pteridin-6-yl]phenol …
Matched Description: … An NSAID that inhibits PI-3K gamma and delta. …
Matched Iupac: … 3-[2,4-diamino-7-(3-hydroxyphenyl)pteridin-6-yl]phenol …
Matched Description: … An NSAID that inhibits PI-3K gamma and delta. …
Pterostilbene
Investigational
Matched Synonyms: … PHENOL, 4-((1E)-2-(3,5-DIMETHOXYPHENYL)ETHENYL)- …
Matched Iupac: … 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol …
Matched Iupac: … 4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]phenol …
Phenyl-uridine-5'-diphosphate
Experimental
Matched Name: … Phenyl-uridine-5'-diphosphate …
Matched Iupac: … 3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy(phenoxy …
Matched Iupac: … 3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy(phenoxy …
(4-(trifluoromethoxy)phenyl)urea
Experimental
Matched Name: … (4-(trifluoromethoxy)phenyl)urea …
Matched Iupac: … [4-(trifluoromethoxy)phenyl]urea …
Matched Iupac: … [4-(trifluoromethoxy)phenyl]urea …
Clobazam
Clobazam belongs to the 1,5-benzodiazepine class of drugs and is marketed under different names, Onfi, Frisium, Urbanyl, and others. . Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis and discovery of the first benzodiazepine chlordiazepoxide in the 1950s. Unlike older 1,4-benzodiazepines, clobazam has...
Approved
Illicit
Matched Synonyms: … 7-Chloro-1-methyl-5-phenyl-1,5-dihydro-benzo[b][1,4]diazepine-2,4-dione ... 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …
Matched Description: … Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis ... , Frisium, Urbanyl, and others. ... with Lennox-Gastaut syndrome in adults and children aged two years and older. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-2,4-dione …
Matched Description: … Clobazam was first synthesized in 1966 and first published in 1969, following the incidental synthesis ... , Frisium, Urbanyl, and others. ... with Lennox-Gastaut syndrome in adults and children aged two years and older. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Lufenuron
Lufenuron is used in veterinary for the control of flea.
Experimental
Vet approved
Matched Synonyms: … 1-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-(2,6-difluorobenzoyl)urea ... N-({[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino}carbonyl)-2,6-difluorobenzamide …
Matched Iupac: … 1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea …
Matched Description: … Lufenuron is used in veterinary for the control of flea. …
Matched Iupac: … 1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-(2,6-difluorobenzoyl)urea …
Matched Description: … Lufenuron is used in veterinary for the control of flea. …
Biperiden
A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
Approved
Investigational
Matched Synonyms: … alpha-5-norbornen-2-yl-alpha-phenyl-1-piperidinepropanol ... 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-yl-propan-1-ol ... alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-1-piperidinepropanol …
Matched Iupac: … 1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Description: … A muscarinic antagonist that has effects in both the central and peripheral nervous systems. ... It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. ... It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine …
Matched Iupac: … 1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenyl-3-(piperidin-1-yl)propan-1-ol …
Matched Description: … A muscarinic antagonist that has effects in both the central and peripheral nervous systems. ... It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. ... It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine …
4-(1H-IMIDAZOL-1-YL)PHENOL
Experimental
Matched Name: … 4-(1H-IMIDAZOL-1-YL)PHENOL …
Matched Iupac: … 4-(1H-imidazol-1-yl)phenol …
Matched Iupac: … 4-(1H-imidazol-1-yl)phenol …
Cerdulatinib
Cerdulatinib is under investigation in clinical trial NCT04021082 (CELTIC-1: A Phase 2B Study of Cerdulatinib in Patients With Relapsed/refractory Peripheral T-cell Lymphoma (PTCL)).
Investigational
Matched Synonyms: … 4-(cyclopropylamino)-2-((4-(4-(ethanesulfonyl)piperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide ... 5-pyrimidinecarboxamide, 4-(cyclopropylamino)-2-((4-(4-(ethylsulfonyl)-1-piperazinyl)phenyl)amino)- …
Matched Iupac: … 4-(cyclopropylamino)-2-({4-[4-(ethanesulfonyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamide …
Matched Iupac: … 4-(cyclopropylamino)-2-({4-[4-(ethanesulfonyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamide …
VAD-044
VAD-044 is an allosteric AKT inhibitor developed by Vaderis Therapeutics AG. It is being investigated for the treatment of Hereditary Hemorrhagic Telangiectasia.
Investigational
Matched Synonyms: … 6-(4-((1S,3S)-1-amino-3-hydroxycyclobutyl)phenyl)-1-ethyl-7-phenyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)- …
Matched Description: … It is being investigated for the treatment of Hereditary Hemorrhagic Telangiectasia.[L46098] …
Matched Description: … It is being investigated for the treatment of Hereditary Hemorrhagic Telangiectasia.[L46098] …
5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid
Investigational
Matched Synonyms: … 5-((trans-4-(4-(trifluoromethoxy)phenyl)cyclohexyl)oxy)-1h-1,2,3-triazole-4-carboxylic acid ... 5-[[trans-4-[(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid …
Matched Name: … 5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid …
Matched Iupac: … 5-{[(1r,4r)-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy}-1H-1,2,3-triazole-4-carboxylic acid …
Matched Name: … 5-[[trans-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy]-1H-1,2,3-triazole-4-carboxylic acid …
Matched Iupac: … 5-{[(1r,4r)-4-[4-(trifluoromethoxy)phenyl]cyclohexyl]oxy}-1H-1,2,3-triazole-4-carboxylic acid …
SP-876
Experimental
Matched Synonyms: … 1-[(4-{[(1S)-1,3-Dicarboxypropyl]carbamoyl}phenyl)sulfonyl]-D-prolyl-β-alanine …
Matched Iupac: … (2S)-2-[(4-{[(2R)-2-[(2-carboxyethyl)carbamoyl]pyrrolidin-1-yl]sulfonyl}phenyl)formamido]pentanedioic …
Matched Iupac: … (2S)-2-[(4-{[(2R)-2-[(2-carboxyethyl)carbamoyl]pyrrolidin-1-yl]sulfonyl}phenyl)formamido]pentanedioic …
Meloxicam
Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis. With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and...
Approved
Vet approved
Matched Description: … Meloxicam is available in oral, transdermal, and intravenous formulations. ... relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and ... [A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require …
Matched Categories: … bupivacaine and meloxicam ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … MOXIC FORTE ... NULOX FORTE ... NIFLAMIN® PL FORTE 15 MG …
Matched Categories: … bupivacaine and meloxicam ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … MOXIC FORTE ... NULOX FORTE ... NIFLAMIN® PL FORTE 15 MG …
Trimethobenzamide
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric...
Approved
Investigational
Matched Synonyms: … N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4,5-trimethoxybenzamide …
Matched Iupac: … N-({4-[2-(dimethylamino)ethoxy]phenyl}methyl)-3,4,5-trimethoxybenzamide …
Matched Description: … Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. …
Matched Categories: … Antihistamines for Systemic Use …
Matched Iupac: … N-({4-[2-(dimethylamino)ethoxy]phenyl}methyl)-3,4,5-trimethoxybenzamide …
Matched Description: … Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. …
Matched Categories: … Antihistamines for Systemic Use …
Imolamine
Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3-phenyl-4,5-dihydro-1,2,3-oxadiazol,-4-yl)ethyl]amine. It is developed under the brand name Coremax by Novartis consumer health SA.
Investigational
Matched Synonyms: … 3-Phenyl-4-diethylaminoethyl-5-imino-1,2,4-oxadiazol …
Matched Iupac: … diethyl[2-(5-imino-3-phenyl-4,5-dihydro-1,2,4-oxadiazol-4-yl)ethyl]amine …
Matched Description: … Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3-phenyl …
Matched Iupac: … diethyl[2-(5-imino-3-phenyl-4,5-dihydro-1,2,4-oxadiazol-4-yl)ethyl]amine …
Matched Description: … Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3-phenyl …
Minaprine
Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
Approved
Matched Synonyms: … 4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholine ... N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine …
Matched Description: … amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Matched Description: … amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Dexibuprofen
Dexibuprofen, S(+)-ibuprofen, is a non-steroidal anti-inflammatory drug (NSAID). It is a pharmacologically effective enantiomer of racemic ibuprofen that differs in physicochemical properties. It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer. Dexibuprofen has a...
Approved
Investigational
Matched Iupac: … (2S)-2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … the racemic ibuprofen and displays improved oral bioavilability [A19259]. ... For Metabolism, Enzymes, Carriers, Transporters Sections, refer to [Ibuprofen]. ... Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with …
Matched Mixtures name: … TAFLAX®FORTE TABLETAS RECUBIERTAS ... TAFLAX®FORTE TABLETAS RECUBIERTAS …
Matched Categories: … Ibuprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Seractil forte 400 mg - Filmtabletten ... TRADIL FORT 400 MG FILM TABLET, 50 ADET ... TRADIL FORT 400 MG FILM TABLET, 10 ADET …
Matched Description: … the racemic ibuprofen and displays improved oral bioavilability [A19259]. ... For Metabolism, Enzymes, Carriers, Transporters Sections, refer to [Ibuprofen]. ... Dexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with …
Matched Mixtures name: … TAFLAX®FORTE TABLETAS RECUBIERTAS ... TAFLAX®FORTE TABLETAS RECUBIERTAS …
Matched Categories: … Ibuprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Seractil forte 400 mg - Filmtabletten ... TRADIL FORT 400 MG FILM TABLET, 50 ADET ... TRADIL FORT 400 MG FILM TABLET, 10 ADET …
Displaying drugs 651 - 675 of 1983 in total