Displaying drugs 651 - 675 of 776 in total
MK-7288
Investigational
Matched Synonyms: … Spiro(cyclohexane-1,5'(7'h)-furo(3,4-b)pyridine)-4-carboxamide, 2'-methoxy-n-methyl-7'-oxo-n-(2-(1-piperidinyl …
Matched Iupac: … 1r,4r)-2'-methoxy-N-methyl-7'-oxo-N-[2-(piperidin-1-yl)ethyl]-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine …
Matched Iupac: … 1r,4r)-2'-methoxy-N-methyl-7'-oxo-N-[2-(piperidin-1-yl)ethyl]-7'H-spiro[cyclohexane-1,5'-furo[3,4-b]pyridine …
5-methyltetrahydrofolic acid
5-methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases (also called methionine synthases).
Investigational
Nutraceutical
Matched Synonyms: … 5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid …
Matched Description: … It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives …
Matched Description: … It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives …
Methotrexate
Methotrexate is a folate derivative that inhibits several enzymes responsible for nucleotide synthesis. This inhibition leads to suppression of inflammation as well as prevention of cell division. Because of these effects, methotrexate is often used to treat inflammation caused by arthritis or to control cell division in neoplastic diseases such...
Approved
Matched Synonyms: … N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid …
Matched Description: … inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and ... Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … inflammation caused by arthritis or to control cell division in neoplastic diseases such as breast cancer and ... Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Ketoconazole
Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Description: … [clotrimazole], due to its broad spectrum and good absorption. ... Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal ... synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and …
Matched Categories: … Sex Hormones and Insulins ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … ONOFIN-K ... MI-KE-SON´S ... MI-KE-SON´S-V …
Matched Categories: … Sex Hormones and Insulins ... Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … ONOFIN-K ... MI-KE-SON´S ... MI-KE-SON´S-V …
N-{[6-(PENTYLOXY)NAPHTHALEN-2-YL]SULFONYL}-D-GLUTAMIC ACID
Experimental
Matched Name: … N-{[6-(PENTYLOXY)NAPHTHALEN-2-YL]SULFONYL}-D-GLUTAMIC ACID …
Avizakimab
Avizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care).
Investigational
Matched Synonyms: … Immunoglobulin g1 (251-tyrosine,253-threonine,255-glutamic acid), anti-(human interleukin 21) (human-mus …
Streptococcus pneumoniae type 9V capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 9V capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 9v individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Name: … Streptococcus pneumoniae type 9V capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 9V capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 9V capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 14 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Name: … Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Streptococcus pneumoniae type 18C capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 18c individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Name: … Streptococcus pneumoniae type 18C capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 18c capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 6a individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Investigational
Matched Name: … Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Description: … Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 33F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Name: … Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 11A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Description: … Streptococcus pneumoniae type 11A capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE
Experimental
Matched Name: … 3-METHOXY-6-[4-(3-METHYLPHENYL)-1-PIPERAZINYL]PYRIDAZINE …
Matched Iupac: … 3-methoxy-6-[4-(3-methylphenyl)piperazin-1-yl]pyridazine …
Matched Iupac: … 3-methoxy-6-[4-(3-methylphenyl)piperazin-1-yl]pyridazine …
Quisovalimab
Investigational
Matched Synonyms: … Immunoglobulin G4 [230-proline,237-glutamic acid], anti-(human tumor necrosis factor superfamily protein …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Sulanemadlin
Investigational
Matched Synonyms: … N-acetyl-l-leucyl-l-threonyl-l-phenylalanyl-cyclo(d-r8-l-glutamyl-ltyrosyl-ltryptophanyl-l-alanyl-l-glutaminyl-l-leucyl-l-s5 …
Selpercatinib
Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes.[A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers. Although multikinase inhibitors, including cabozantinib, ponatinib, sorafenib, sunitinib, and vandetanib, have shown efficacy in RET-driven cancers, their...
Approved
Investigational
Matched Synonyms: … 6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine …
Matched Iupac: … 6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl}pyridin-3-yl)pyrazolo[1,5-a]pyridine …
Matched Description: … Although multikinase inhibitors, including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and ... Selpercatinib (LOXO-292) and pralsetinib (BLU-667) represent the first generation of specific RET RTK …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 6-{6-[(6-methoxypyridin-3-yl)methyl]-3,6-diazabicyclo[3.1.1]heptan-3-yl}pyridin-3-yl)pyrazolo[1,5-a]pyridine …
Matched Description: … Although multikinase inhibitors, including [cabozantinib], [ponatinib], [sorafenib], [sunitinib], and ... Selpercatinib (LOXO-292) and pralsetinib (BLU-667) represent the first generation of specific RET RTK …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Streptococcus pneumoniae type 19F capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 19F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 19F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Name: … Streptococcus pneumoniae type 19F capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 19F capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 19F capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Streptococcus pneumoniae type 23F capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 23f capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 23F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Name: … Streptococcus pneumoniae type 23F capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 23f capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 23f capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 3 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Description: … Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Streptococcus pneumoniae type 7F capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 7F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 7F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 7F capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 7F capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Description: … Streptococcus pneumoniae type 7F capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Streptococcus pneumoniae type 19A capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 19a capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 19A individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 19A capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 19a capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Description: … Streptococcus pneumoniae type 19a capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 22F individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Matched Name: … Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Description: … under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and ... Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen
Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 8 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). The saccharides...
Approved
Matched Name: … Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen …
Matched Description: … Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
Matched Description: … Streptococcus pneumoniae type 8 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is ... The saccharides in the vaccine are prepared from purified polysaccharides that are chemically activated …
ORC-13661
ORC-13661 is under investigation in clinical trial NCT05730283 (Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin).
Investigational
Matched Synonyms: … 4R,6S)-2-[[[(4-Chlorophenyl)amino]carbonyl]amino]-4,5,6,7-tetrahydro-5-methyl-4,6-ethanothieno[3,2-c]pyridine ... 4,6-Ethanothieno[3,2-c]pyridine-3-carboxamide, 2-[[[(4-chlorophenyl)amino]carbonyl]amino]-4,5,6,7-tetrahydro …
Carbinoxamine
Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. The product label for carbinoxamine as an over the counter cough and...
Approved
Matched Synonyms: … 2-(p-chloro-α-(2-(dimethylamino)ethoxy)benzyl)pyridine …
Matched Description: … The product label for carbinoxamine as an over the counter cough and cold medicine is being modified ... to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many ... labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and …
Matched Description: … The product label for carbinoxamine as an over the counter cough and cold medicine is being modified ... to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many ... labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and …
Displaying drugs 651 - 675 of 776 in total