Displaying drugs 676 - 700 of 1157 in total
Tomaralimab
Tomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function).
Investigational
Matched Synonyms: … anti-Tlr2 monoclonal antibody OPN-305 ... Humanized IGG4 monoclonal antibody against toll-like receptor 2 for prevention of ischemia/reperfusion …
Matched Description: … under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mephentermine
A sympathomimetic agent with mainly indirect effects on adrenergic receptors. It is used to maintain blood pressure in hypotensive states, for example, following spinal anesthesia. Although the central stimulant effects of mephentermine are much less than those of amphetamine, its use may lead to amphetamine-type dependence. (From Martindale, The Extra...
Approved
Matched Salts name: … Mephentermine sulfate …
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Products: … Wyamine Sulfate Injection Liq 30mg/ml …
Matched Categories: … Adrenergic and Dopaminergic Agents …
Matched Products: … Wyamine Sulfate Injection Liq 30mg/ml …
Acetylcholine
A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is generally not used as an administered drug because it is broken down very rapidly by cholinesterases,...
Approved
Investigational
Matched Description: … parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in ... Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, …
Matched Salts name: … Acetylcholine chloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Miochol E Acetylcholine Chloride Oph Soln …
Matched Salts name: … Acetylcholine chloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Miochol E Acetylcholine Chloride Oph Soln …
Oxybutynin
Overactive bladder (OAB) is a common condition negatively impacting the lives of millions of patients worldwide. Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life.[A185996,A185999]
Oxybutynin, also marketed as Ditropan XL, is an anticholinergic medication used for...
Approved
Investigational
Matched Description: … embarrassment and a poor quality of life. ... Due to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social ... used for the relief of overactive bladder symptoms that has been optimized for high levels of safety and …
Matched Salts name: … Oxybutynin chloride …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … Oxybutynin Chloride ... Pat-oxybutynin Chloride ER ... Oxybutynin Chloride Extended Release …
Matched Salts name: … Oxybutynin chloride …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … Oxybutynin Chloride ... Pat-oxybutynin Chloride ER ... Oxybutynin Chloride Extended Release …
Pyridoxine phosphate
Experimental
Matched Synonyms: … Pyridoxine 5-phosphate …
Matched Name: … Pyridoxine phosphate …
Matched Categories: … Enzymes and Coenzymes …
Matched Name: … Pyridoxine phosphate …
Matched Categories: … Enzymes and Coenzymes …
Chlorphenesin carbamate
Approved
Vet approved
Withdrawn
Matched Synonyms: … Chlorphenesin carbamate ... 1,2-propanediol-3-(p-chlorophenoxy)-1-carbamate ... 3-(4-chlorophenoxy)-1,2-propanediol-1-carbamate …
Matched Name: … Chlorphenesin carbamate …
Matched Iupac: … 3-(4-chlorophenoxy)-2-hydroxypropyl carbamate …
Matched Name: … Chlorphenesin carbamate …
Matched Iupac: … 3-(4-chlorophenoxy)-2-hydroxypropyl carbamate …
Coltuximab ravtansine
Coltuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic leukemia (ALL).
Investigational
Matched Synonyms: … Anti-CD19 humanized monoclonal antibody conjugated to DM4 …
Matched Description: … Coltuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Matched Description: … Coltuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
PAT-SM6
Investigational
Matched Synonyms: … Recombinant human monoclonal IgM antibody targeting glucose regulated protein 78 …
Ertumaxomab
Ertumaxomab is under investigation in clinical trial NCT00522457 (Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer After Progression on Trastuzumab Therapy).
Investigational
Matched Synonyms: … Anti-cd3 x anti-her-2-neu bispecific monoclonal antibody …
Matched Description: … Ertumaxomab is under investigation in clinical trial NCT00522457 (Phase II Study With the Trifunctional Antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Ertumaxomab is under investigation in clinical trial NCT00522457 (Phase II Study With the Trifunctional Antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Orotidylic acid
Experimental
Matched Synonyms: … Orotidine 5'-phosphate ... 5-(Dihydrogen phosphate)orotidine ... orotidine 5'-(dihydrogen phosphate) …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Sodium phosphate, dibasic, unspecified form
Approved
Experimental
Matched Synonyms: … Sodium phosphate, dibasic, unspecified …
Matched Name: … Sodium phosphate, dibasic, unspecified form …
Matched Mixtures name: … Phosphate ... Up and Up Ready To Use Enema ... Pure and Gentle Laxative …
Matched Name: … Sodium phosphate, dibasic, unspecified form …
Matched Mixtures name: … Phosphate ... Up and Up Ready To Use Enema ... Pure and Gentle Laxative …
sn-glycerol 3-phosphate
Experimental
Matched Synonyms: … Glycerol-3-phosphate ... (R)-glycerol 1-phosphate ... D-Glycerol 1-phosphate …
Matched Name: … sn-glycerol 3-phosphate …
Matched Name: … sn-glycerol 3-phosphate …
NADPH
Experimental
Matched Synonyms: … Dihydronicotinamide-adenine dinucleotide phosphate ... Reduced nicotinamide adenine dinucleotide phosphate …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Satralizumab
Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to tocilizumab, which is produced in Chinese hamster ovary cells and based on an IgG2 framework. Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central...
Approved
Matched Synonyms: … Humanised anti-IL-6 receptor monoclonal antibody …
Matched Description: … Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL- ... formulated with "recycling antibody technology" whereby the association of satralizumab to IL-6 receptors ... Satralizumab was first approved for use in Canada in June 2020 for the treatment of AQP4 antibody-positive …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … Satralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL- ... formulated with "recycling antibody technology" whereby the association of satralizumab to IL-6 receptors ... Satralizumab was first approved for use in Canada in June 2020 for the treatment of AQP4 antibody-positive …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
A166
A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable valine citrulline linker.
Investigational
Matched Synonyms: … Recombinant humanized IgG1 anti-HER2 monoclonal antibody conjugated to Duostatin-5 …
Matched Description: … A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) ... site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable …
Matched Description: … A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) ... site-specifically conjugated to an anti-HER2 antibody (trastuzumab) via a stable protease-cleavable …
Ontamalimab
Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Investigational
Matched Synonyms: … human IgG2 monoclonal antibody directed against the mucosal addressin cell adhesion molecule ... human IgG2 anti-monoclonal antibody directed against mucosal addressin cell adhesion molecule (MAdCAM …
Matched Description: … Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Anetumab ravtansine
Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Anti-mesothelin antibody-drug conjugate BAY 94-9343 …
Matched Description: … Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Matched Description: … Anetumab ravtansine is under investigation in clinical trial NCT03455556 (Anetumab Ravtansine and Atezolizumab …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
CMG901
CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload.
Investigational
Matched Synonyms: … an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload …
Matched Description: … CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload. …
Matched Description: … CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload. …
Phosphorylcolamine
Experimental
Matched Synonyms: … Colamine phosphate ... 2-aminoethyl dihydrogen phosphate …
3'-phospho-5'-adenylyl sulfate
3'-phospho-5'-adenylyl sulfate is a key intermediate in the formation by living cells of sulfate esters of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate. It is formed from sulfate ion and ATP in a two-step process. This compound also is an important step in the process...
Experimental
Matched Synonyms: … 3'-phosphoadenylyl sulfate …
Matched Name: … 3'-phospho-5'-adenylyl sulfate …
Matched Description: … of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate ... It is formed from sulfate ion and ATP in a two-step process. ... This compound also is an important step in the process of sulfur fixation in plants and microorganisms …
Matched Name: … 3'-phospho-5'-adenylyl sulfate …
Matched Description: … of phenols, alcohols, steroids, sulfated polysaccharides, and simple esters, such as choline sulfate ... It is formed from sulfate ion and ATP in a two-step process. ... This compound also is an important step in the process of sulfur fixation in plants and microorganisms …
Dexmedetomidine
An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Precedex Dexmedetomidine HCI Chloride ... Dexmedetomidine Hydrochloride in Sodium Chloride ... Dexmedetomidine Hydrochloride In 0.9% Sodium Chloride …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Precedex Dexmedetomidine HCI Chloride ... Dexmedetomidine Hydrochloride in Sodium Chloride ... Dexmedetomidine Hydrochloride In 0.9% Sodium Chloride …
Dihydroxyacetone phosphate
Dihydroxyacetone phosphate is an important intermediate in lipid biosynthesis and in glycolysis. Dihydroxyacetone phosphate has been investigated for the treatment of Lymphoma, Large-Cell, Diffuse.
Investigational
Matched Synonyms: … Glycerone phosphate ... 3-hydroxy-2-oxopropyl phosphate ... 1,3-Dihydroxyacetone 1-phosphate …
Matched Name: … Dihydroxyacetone phosphate …
Matched Description: … Dihydroxyacetone phosphate is an important intermediate in lipid biosynthesis and in glycolysis. ... Dihydroxyacetone phosphate has been investigated for the treatment of Lymphoma, Large-Cell, Diffuse. …
Matched Categories: … Sugar Phosphates …
Matched Name: … Dihydroxyacetone phosphate …
Matched Description: … Dihydroxyacetone phosphate is an important intermediate in lipid biosynthesis and in glycolysis. ... Dihydroxyacetone phosphate has been investigated for the treatment of Lymphoma, Large-Cell, Diffuse. …
Matched Categories: … Sugar Phosphates …
Triethyl phosphate
Experimental
Matched Synonyms: … Ethyl phosphate ... Tris(ethyl) phosphate …
Matched Name: … Triethyl phosphate …
Matched Iupac: … triethyl phosphate …
Matched Name: … Triethyl phosphate …
Matched Iupac: … triethyl phosphate …
Ferric subsulfate
Ferric subsulfate is a stypic or hemostatic agent that causes agglutination of surface proteins resulting in local hemostasis. It has the chemical formula Fe4(OH)2(SO4)5. It is used after superficial skin biopsies.
Approved
Experimental
Matched Synonyms: … basic ferric sulfate solution …
Displaying drugs 676 - 700 of 1157 in total