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Displaying drugs 676 - 700 of 1247 in total
Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). DEB is caused by mutations in the COL7A1 gene that...
Approved
Matched Synonyms: … Dna (recombinant herpes simplex virus type 1 strain kos plasmid vector kb103 human collagen col7a1-specifying …
Matched Description: … Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector ... [L46916] DEB is caused by mutations in the _COL7A1_ gene that encodes collagen VII (COL7), a major component ... Beremagene geperpavec is genetically modified to deliver _COL7A1_, thereby restoring the levels of the COL7
Matched Categories: … Cellular and Gene Therapy ... Preparations for Treatment of Wounds and Ulcers …
Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. According to the Centers for Disease Control...
Approved
Investigational
Matched Synonyms: … Hepatitis B immune globulin human ... Hepatitis B immune globulin (human) ... Human hepatitis B immunoglobulin …
Matched Description: … The preparation is tested for absence of HIV, HCV, herpes virus, and reovirus. ... According to the Centers for Disease Control and Prevention (CDC), the hepatitis B vaccine was the first ... During the process, viruses are deactivated, and in the final steps, solvents used in the preparation …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Immune Sera and Immunoglobulins ... Human Immunoglobulin …
Matched Products: … HEPATECT®CP 500 UI (INMUNOGLOBULINA HUMANA CONTRA EL VIRUS DE LA HEPATITIS B). …
Investigational
Matched Synonyms: … Blood-group a trisaccharide …
Investigational
Matched Synonyms: … Human IgG1 anti-human cytomegalovirus monoclonal antibody LJP538 …
AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.
Investigational
Matched Synonyms: … Tgf-.beta. ligand trap comprised of tgf-.beta. receptor ectodomains fused to a human fc domain (avid- …
Matched Name: … AVID-200 …
Matched Description: … AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein. …
Investigational
Matched Name: … Autologous Human Peripheral Blood Lymphocytes …
Investigational
Matched Synonyms: … Hepatitis C immune globulin (human) ... Hepatitis C human polyclonal immune globulin ... Hepatitis C virus immune globulin (human) …
Matched Name: … Hepatitis C immune globulin (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Recombinant human heparan-N-sulfatase (rhHNS) is under investigation for the treatment mucopolysaccharidosis type IIIA.
Investigational
Matched Synonyms: … Recombinant human heparan-N-sulfatase …
Matched Name: … Heparan-N-sulfatase (human, recombinant) …
Matched Description: … type IIIA. ... Recombinant human heparan-N-sulfatase (rhHNS) is under investigation for the treatment mucopolysaccharidosis …
A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.
Approved
Experimental
Investigational
Matched Synonyms: … Beet sugar …
Matched Description: … It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively ... as a food and a sweetener. ... A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. …
Matched Categories: … Diet, Food, and Nutrition …
Binetrakin has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and Leukemia, Acute Myelogenous (AML), among others.
Investigational
Matched Synonyms: … Interleukin 4 human ... Interleukin 4 (human) ... Interleukin-4 (human; nonglycosylated) …
Matched Description: … Lymphoma (NHL), Myelodysplastic Syndrome (MDS), and Leukemia, Acute Myelogenous (AML), among others. ... Binetrakin has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, Non-Hodgkin's …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
VaxSyn HIV-1 is a recombinant form of the HIV envelope protein gp 160 developed by MicroGeneSys and the National Institute of Allergy and Infectious Diseases (NIAID).
Investigational
Matched Synonyms: … Human T-lymphotropic virus type III Gp160 antigens …
Matched Description: … VaxSyn HIV-1 is a recombinant form of the HIV envelope protein gp 160 developed by MicroGeneSys and the ... National Institute of Allergy and Infectious Diseases (NIAID). …
Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996....
Approved
Vet approved
Matched Description: … Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. ... The hemodynamic and respiratory depressive effects of sevoflurane are well tolerated, and most patients ... [L42340] It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition …
Matched Products: … Truemed Group LLC …
BCG SSI has been used in trials studying Tuberculosis.
Investigational
Matched Name: … Bacillus calmette-guerin substrain danish 1331 live antigen …
Matched Description: … BCG SSI has been used in trials studying Tuberculosis. …
Matched Categories: … Live Attenuated Bacillus Calmette-Guerin Vaccine …
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved...
Approved
Matched Synonyms: … Microplasmin (synthetic human) ... Recombinant human microplasmin …
Matched Description: … Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. ... Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Denenicokin is under investigation in clinical trial NCT01152788 (Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma).
Investigational
Matched Synonyms: … Recombinant human IL-21 ... L-METHIONYL(HUMAN INTERLEUKIN-21) ... RECOMBINANT HUMAN INTERLEUKIN 21 …
Cholecystokinin ( also known as CCK or CCK-PZ) is a peptide hormone of the gastrointestinal system which is responsible for stimulating the digestion of fat and protein. Cholecystokinin, previously called pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum (the first portion of the small intestine) and leads...
Approved
Investigational
Matched Synonyms: … Human CCK-33 ... Human cholecystokinin-33 …
Matched Description: … This hormone has also been shown to have positive effects on enteric smooth muscle contraction and on ... CCK also acts as an appetite suppressant and has been studied for weight management regimens [L1637]. ... in the duodenum (the first portion of the small intestine) and leads to the release of bile and digestive …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cholagogues and Choleretics ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Thrombin Alfa is a human coagulation protein produced via recombinant DNA technology from a genetically modified CHO cell line. Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human thrombin. Thrombin Alfa precursor is secreted to culture medium as single chain form that is proteolytically...
Approved
Matched Synonyms: … Thrombin (synthetic human) ... Human Thrombin (recombinant, glycosylated) …
Matched Description: … The cell line used to manufacture Thrombin Alfa has been tested and shown to be free of known infectious ... Thrombin Alfa is identical in amino acid sequence and structurally similar to naturally occurring human ... that is proteolytically converted to a two-chain active form (using a protein derived from snakes) and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Infant botulism is a rare infectious disease occurring in infants in which Clostridium botulinum colonize the large intestine and being to produce botulinum neurotoxin directly in the gut. As these neurotoxins interfere with cholinergic nervous transmission, patients initially present with evident of loss of muscle tone (e.g. constipation, ptosis, feeding...
Approved
Matched Synonyms: … Botulism immune globulin IV human ... Botulism immune globulin intravenous (human) ... Human-derived botulism antitoxin antibodies …
Matched Name: … Human botulinum neurotoxin A/B immune globulin …
Matched Description: … 2003[L39814] and has since been used to treat more than 2100 cases of infant botulism. ... infectious disease occurring in infants in which _Clostridium botulinum_ colonize the large intestine and ... Treatment and Prevention Program[L39829] and comprises IgG antibodies derived from pooled adult plasma …
Matched Categories: … Human Immunoglobulin G …
Investigational
Matched Synonyms: … Recombinant human IgG1 Fc multimer ... Recombinant Multimerized Human IgG1 Fc …
Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.
Approved
Vet approved
Matched Description: … Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Coly-Mycin M ... COLIS-TEK …
Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation factor deficiency induced by Vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with acute major bleeding.
Approved
Matched Synonyms: … Coagulation factor II human ... Coagulation factor II (human) ... Human coagulation factor II …
Matched Description: … Prothrombin Complex Concentrate (Human), is indicated for the urgent reversal of acquired coagulation …
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU ... Octaplex Powder and Solvent for Solution for Infusion …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Experimental
Matched Name: … Interleukin-1 alpha, human recombinant …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Human vaccinia immune globulin (VIG) is a sterile solution containing the purified gamma globulin (IgG) fraction of plasma taken from healthy donors previously vaccinated with live vaccinia virus vaccine who possess high titers of anti-vaccinia virus antibody [FDA Label, A33814]. The IgG fraction is purified by the anion-exchange column chromatography...
Approved
Matched Synonyms: … Human vaccinia immune globulin ... Vaccinia Immune Globulin (Human) Intravenous ... Vaccinia immune globulin intravenous (human) …
Matched Name: … Human vaccinia virus immune globulin …
Matched Description: … Nevertheless, VIG by virtue of the way it is produced is a poorly characterized and highly variable human ... The IgG fraction is purified by the anion-exchange column chromatography method and the solution is solvent ... is only available in very limited quantities - all factors that may intervene with its availability and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Human Immunoglobulin G …
Investigational
Matched Synonyms: … Pegylated human c-peptide …
Matched Name: … Pegylated synthetic human c-peptide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Investigational
Matched Name: … Human umbilical tissue derived cells …
Displaying drugs 676 - 700 of 1247 in total