Displaying drugs 676 - 700 of 2954 in total
Indoximod
Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.
Investigational
Matched Synonyms: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid ... 1-methyl-D-tryptophan …
Matched Iupac: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid …
Matched Description: … Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tryptophan Oxygenase, antagonists & inhibitors ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid …
Matched Description: … Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tryptophan Oxygenase, antagonists & inhibitors ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
NUC-7738
NUC-7738 is under investigation in clinical trial NCT03829254 (A Safety, Pharmacokinetic and Clinical Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma).
Investigational
Matched Synonyms: … L-Alanine, N-(3′-deoxy-P-phenyl-5′-adenylyl)-, phenylmethyl ester (ACI) …
Matched Description: … NUC-7738 is under investigation in clinical trial NCT03829254 (A Safety, Pharmacokinetic and Clinical ... Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma). …
Matched Description: … NUC-7738 is under investigation in clinical trial NCT03829254 (A Safety, Pharmacokinetic and Clinical ... Activity Study of NUC-7738 in Patients With Advanced Solid Tumours and Lymphoma). …
Fludrocortisone
Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Matched International brands: … Florinef Acetaat …
Matched Description: … A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and …
Matched Salts name: … Fludrocortisone acetate …
Matched Categories: … Sex Hormones and Insulins ... fludrocortisone and antiinfectives ... fludrocortisone and antiinfectives ... Hormones, Hormone Substitutes, and Hormone Antagonists ... fludrocortisone and antiinfectives …
Matched Products: … Florinef Acetate ... Fludrocortisone Acetate ... Florinef Acetate 0.1mg …
Matched Description: … A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and …
Matched Salts name: … Fludrocortisone acetate …
Matched Categories: … Sex Hormones and Insulins ... fludrocortisone and antiinfectives ... fludrocortisone and antiinfectives ... Hormones, Hormone Substitutes, and Hormone Antagonists ... fludrocortisone and antiinfectives …
Matched Products: … Florinef Acetate ... Fludrocortisone Acetate ... Florinef Acetate 0.1mg …
Desoxycorticosterone acetate
Approved
Matched Synonyms: … Desoxycortone acetate ... Deoxycorticosterone acetate ... 11-deoxycorticosterone acetate …
Matched Name: … Desoxycorticosterone acetate …
Matched Iupac: … -oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Desoxycorticosterone acetate …
Matched Iupac: … -oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Clavulanic acid
Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Synonyms: … Clavulanic acid ... Acide clavulanique ... Acidum clavulanicum …
Matched Name: … Clavulanic acid …
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … [T665] Clavulanic acid is derived from the organism Streptomyces clavuligerus. ... Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin ... [A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav …
Matched Mixtures name: … ACIX® ... AMOXICILLINA E ACIDO CLAVULANICO KABI ... AMOXICILLINA E ACIDO CLAVULANICO KABI …
Matched Name: … Clavulanic acid …
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … [T665] Clavulanic acid is derived from the organism Streptomyces clavuligerus. ... Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin ... [A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav …
Matched Mixtures name: … ACIX® ... AMOXICILLINA E ACIDO CLAVULANICO KABI ... AMOXICILLINA E ACIDO CLAVULANICO KABI …
Methionine Phosphonate
Experimental
Matched Name: … Methionine Phosphonate …
Matched Iupac: … [(1R)-1-amino-3-(methylsulfanyl)propyl]phosphonic acid …
Matched Iupac: … [(1R)-1-amino-3-(methylsulfanyl)propyl]phosphonic acid …
D-Threonine
Experimental
Matched Name: … D-Threonine …
Matched Iupac: … (2R,3R)-2-amino-3-hydroxybutanoic acid …
Matched Iupac: … (2R,3R)-2-amino-3-hydroxybutanoic acid …
Dazukibart
Investigational
Matched Synonyms: … Immunoglobulin G1 [236-alanine,237-alanine,239-alanine,de-C-terminal-lysine], anti-(human interferon …
Aceclofenac
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Synonyms: … glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate ester ... 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid ... 2-[(2',6'-dichlorophenyl)amino]phenylacetoxyacetic acid …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid …
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Acids, Carbocyclic ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid …
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Acids, Carbocyclic ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Etidronic acid
Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Synonyms: … Etidronic acid ... acide étidronique ... acidum etidronicum …
Matched Name: … Etidronic acid …
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid …
Matched Description: … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and …
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... etidronic acid …
Matched Name: … Etidronic acid …
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid …
Matched Description: … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and …
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... etidronic acid …
Dipivefrin
Dipivefrin is a prodrug of adrenaline, which is used to treat glaucoma. It is available as ophthalmic solution (eye drops).
Approved
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Propine ... PROPINE ... Propine Liq 0.1% …
Matched Products: … Propine ... PROPINE ... Propine Liq 0.1% …
Levomefolic acid
Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Synonyms: … acid ... N-[4-[[[(6S)-2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic ... Levomefolic acid …
Matched Name: … Levomefolic acid …
Matched Iupac: … -amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Description: … Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form ... regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate ... of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium and Schizochytrium DHA ... Levomefolate Calcium and Schizochytrium DHA …
Matched Categories: … Folic Acid and Derivatives ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Amino Acids, Acidic ... Amino Acids …
Matched Name: … Levomefolic acid …
Matched Iupac: … -amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid …
Matched Description: … Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form ... regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate ... of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium and Schizochytrium DHA ... Levomefolate Calcium and Schizochytrium DHA …
Matched Categories: … Folic Acid and Derivatives ... Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Amino Acids, Acidic ... Amino Acids …
p-Boronophenylalanine
p-Boronophenylalanine is under investigation in clinical trial NCT00039572 (Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain).
Investigational
Matched Synonyms: … 4-borono-l-phenylalanine ... L-phenylalanine, 4-borono- …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... Amino Acids, Essential …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... Amino Acids, Essential …
Para-Iodo-D-Phenylalanine Hydroxamic Acid
Experimental
Matched Name: … Para-Iodo-D-Phenylalanine Hydroxamic Acid …
beta-2-Thienyl-L-alanine
Experimental
Matched Synonyms: … L-3-(2-thienyl)alanine ... beta-(2-Thienyl)-L-alanine …
Matched Name: … beta-2-Thienyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-(thiophen-2-yl)propanoic acid …
Matched Name: … beta-2-Thienyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-(thiophen-2-yl)propanoic acid …
2,3-Dimercapto-1-propanesulfonic acid
Experimental
Matched Synonyms: … 2,3-Dimercaptopropanesulfonic acid ... 2,3-Dimercapto-1-propane sulfonate …
Matched Name: … 2,3-Dimercapto-1-propanesulfonic acid …
Matched Iupac: … 2,3-disulfanylpropane-1-sulfonic acid …
Matched Name: … 2,3-Dimercapto-1-propanesulfonic acid …
Matched Iupac: … 2,3-disulfanylpropane-1-sulfonic acid …
Mafenide
Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns. In 1998, mafenide acetate was approved under the FDA’s accelerated approval regulations. In November 2022, the use of mafenide acetate (powder...
Approved
Vet approved
Withdrawn
Matched Description: … It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep ... [L36773] In 1998, mafenide acetate was approved under the FDA’s accelerated approval regulations. ... In November 2022, the use of mafenide acetate (powder for 5% topical solution) was withdrawn by the FDA …
Matched Salts name: … Mafenide Acetate …
Matched Categories: … Folic Acid Antagonists ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Mafenide acetate ... Mafenide Acetate …
Matched Salts name: … Mafenide Acetate …
Matched Categories: … Folic Acid Antagonists ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Mafenide acetate ... Mafenide Acetate …
Deutarserine
Deutarserine is under investigation in clinical trial NCT04158687 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-692 as an Adjunctive Treatment in Adults With Schizophrenia).
Investigational
Matched Synonyms: … D-serine-2-d …
Matched Description: … Deutarserine is under investigation in clinical trial NCT04158687 (A Phase 2 Study to Evaluate the Safety and …
Matched Description: … Deutarserine is under investigation in clinical trial NCT04158687 (A Phase 2 Study to Evaluate the Safety and …
Bicine
Experimental
Matched Synonyms: … Diethanol glycine ... N,N-Dihydroxyethyl glycine …
Matched Iupac: … 2-[bis(2-hydroxyethyl)amino]acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … 2-[bis(2-hydroxyethyl)amino]acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
4-Iodo-L-phenylalanine
Experimental
Matched Synonyms: … p-Iodo-L-phenylalanine …
Matched Name: … 4-Iodo-L-phenylalanine …
Matched Iupac: … (2S)-2-amino-3-(4-iodophenyl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Name: … 4-Iodo-L-phenylalanine …
Matched Iupac: … (2S)-2-amino-3-(4-iodophenyl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Phenprocoumon
Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … PHENPROCOUMON ACIS 3MG TAB …
Matched Products: … PHENPROCOUMON ACIS 3MG TAB …
Pantothenyl-Aminoethanol-Acetate Pivalic Acid
Experimental
Matched Name: … Pantothenyl-Aminoethanol-Acetate Pivalic Acid …
Phytic acid
Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications).
Investigational
Matched Synonyms: … Acido fitico ... Fytic acid ... Acide fytique …
Matched Name: … Phytic acid …
Matched Iupac: … {[(1s,2R,3R,4r,5S,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid …
Matched Description: … Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the …
Matched Name: … Phytic acid …
Matched Iupac: … {[(1s,2R,3R,4r,5S,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]oxy}phosphonic acid …
Matched Description: … Phytic acid is under investigation in clinical trial NCT01000233 (Value of Oral Phytate (InsP6) in the …
Abiraterone
Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Description: … hydrolysis by esterases, abiraterone acetate was developed as an orally bioavailable prodrug with enhanced ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... ] and September 2011,[A260880] respectively. …
Matched Salts name: … Abiraterone acetate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Abiraterone Acetate ... Abiraterone acetate ... Abiratred Abiraterone Acetate Tablets 250mg …
Matched Salts name: … Abiraterone acetate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Abiraterone Acetate ... Abiraterone acetate ... Abiratred Abiraterone Acetate Tablets 250mg …
Displaying drugs 676 - 700 of 2954 in total