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Displaying drugs 7051 - 7075 of 11962 in total
Ceramide NP
Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. Ceramide 3 consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid) . It is widely used as a...
Experimental
Matched Synonyms: … N-oloeoyl-4-hydroxysphinganine ... N-(9Z-octadecenoyl)-4-hydroxysphinganine …
Matched Description: … Together with ceramide 1, they synergistically improve the skin barrier function in humans [A27232, A27233 …
Matched Description: … Together with ceramide 1, they synergistically improve the skin barrier function in humans [A27232, A27233 …
Fimasartan
Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the...
Investigational
Matched Iupac: … 2-(2-butyl-4-methyl-6-oxo-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1,6-dihydropyrimidin ... -5-yl)-N,N-dimethylethanethioamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
(4S)-4-(2-NAPHTHYLMETHYL)-D-GLUTAMIC ACID
Experimental
Matched Name: … (4S)-4-(2-NAPHTHYLMETHYL)-D-GLUTAMIC ACID …
Matched Iupac: … (2R,4S)-2-amino-4-[(naphthalen-2-yl)methyl]pentanedioic acid …
Matched Iupac: … (2R,4S)-2-amino-4-[(naphthalen-2-yl)methyl]pentanedioic acid …
4-Nitrocatechol
Experimental
Matched Name: … 4-Nitrocatechol …
Matched Iupac: … 4-nitrobenzene-1,2-diol …
Matched Iupac: … 4-nitrobenzene-1,2-diol …
(5R)-5-{[(2-Amino-3H-purin-6-yl)oxy]methyl}-2-pyrrolidinone
Experimental
Matched Name: … (5R)-5-{[(2-Amino-3H-purin-6-yl)oxy]methyl}-2-pyrrolidinone …
Matched Iupac: … (5R)-5-{[(2-amino-9H-purin-6-yl)oxy]methyl}pyrrolidin-2-one …
Matched Iupac: … (5R)-5-{[(2-amino-9H-purin-6-yl)oxy]methyl}pyrrolidin-2-one …
N,O-didansyl-L-tyrosine
Experimental
Matched Iupac: … (2S)-3-[4-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}oxy)phenyl]-2-[5-(dimethylamino)naphthalene-1- …
Apamistamab iodine I-131
Investigational
CGP 4832
Experimental
Matched Iupac: … -methoxy-3,7,12,14,16,18,22-heptamethyl-26-(morpholin-4-yl)-6,23,27,29-tetraoxo-8,30-dioxa-24-azatetracyclo ... 1-(1-methylpiperidin-3-yl)methyl (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17-trihydroxy-11 ... [23.3.1.1^{4,7}.0^{5,28}]triaconta-1(28),2,4,9,19,21,25-heptaen-13-yl propanedioate …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
AVI-4065
AVI-4065, a phosphorodiamidate Morpholino oligomer (PMO), is an investigational antisense HCV drug. It was developed by Sarepta Therapeutics, Inc. After phase II trials it was cancelled due to lack of potency.
Investigational
SLx-4090
SLx-4090 is a microsomal triglyceride transfer protein (MTTP) inhibitor potentially for the treatment of type 2 diabetes.
Investigational
Matched Iupac: … phenyl 6-[6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-amido]-1,2,3,4-tetrahydroisoquinoline-2-carboxylate …
AVI-4020
AVI-4020 is a neugene antisense drug candidate for the treatment of patients with acute West Nile virus disease who have serious neurological impairment (WNV neuroinvasive disease).
Investigational
CHF 4227
CHF 4227 is a new selective estrogen receptor modulator (SERM). The compound has a high receptor affinity and has shown promising efficacy in the prevention of bone loss in animal models of osteoporosis. Additionally, the compound has shown no uterotrophic activity suggesting a potential therapeutic advantage over drugs normally used...
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
ZSTK-474
ZSTK474 has been used in trials studying the treatment of Neoplasms.
Investigational
Matched Iupac: … 1-[4,6-bis(morpholin-4-yl)-1,3,5-triazin-2-yl]-2-(difluoromethyl)-1H-1,3-benzodiazole …
AZD-4017
AZD-4017 is under investigation in clinical trial NCT01173471 (A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-ocular Pressure).
Investigational
Matched Iupac: … 2-[(3S)-1-[5-(cyclohexylcarbamoyl)-6-(propylsulfanyl)pyridin-2-yl]piperidin-3-yl]acetic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... 11-beta-Hydroxysteroid Dehydrogenase Type 1, antagonists & inhibitors …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... 11-beta-Hydroxysteroid Dehydrogenase Type 1, antagonists & inhibitors …
ACTX-401
ACTX-401 is a single-stranded, non-replicating recombinant adeno-associated viral vector serotype 9 containing the human immunoglobulin u-binding protein 2 cDNA.
Investigational
Onapristone
Onapristone has been used in trials studying the treatment of Prostate Cancer, Recurrent Prostate Cancer, Metastatic Prostate Cancer, Androgen-independent Prostate Cancer, and Progesterone Receptor Positive Tumor: Max 1 Line of Prior Chemotherapy, no Prior Hormone Therapy.
Investigational
Matched Iupac: … [8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one ... (10S,11S,14S,15R,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-14-(3-hydroxypropyl)-15-methyltetracyclo …
Matched Description: … Prostate Cancer, Androgen-independent Prostate Cancer, and Progesterone Receptor Positive Tumor: Max 1 …
Matched Description: … Prostate Cancer, Androgen-independent Prostate Cancer, and Progesterone Receptor Positive Tumor: Max 1 …
Interferon Gamma
Interferon gamma is a Type 1 inflammatory cytokine and the only type II interferon. It has antitumor properties, antiviral activities, and important immunoregulatory functions. The interferon is primarily produced by activated T lymphocytes and natural killer cells.
Investigational
Matched Description: … Interferon gamma is a Type 1 inflammatory cytokine and the only type II interferon. …
R450
R450 is an alpha 1 antagonist that acts to tighten the muscle tone in the bladder. It is being considered for treatment of stress-related urinary incontinence. Phase IIa data for the drug show it reduced the number of incontinent episodes compared to placebo with minimal cardiovascular effects.
Investigational
Matched Description: … R450 is an alpha 1 antagonist that acts to tighten the muscle tone in the bladder. …
p-Cumylphenol
Experimental
Matched Synonyms: … 4-Cumylphenol ... 4-(alpha,alpha-Dimethylbenzyl)phenol …
Matched Iupac: … 4-(2-phenylpropan-2-yl)phenol …
Matched Iupac: … 4-(2-phenylpropan-2-yl)phenol …
Bisphenol A
Experimental
Matched Iupac: … 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Hexestrol
A synthetic estrogen that has been used as a hormonal antineoplastic agent.
Withdrawn
Matched Iupac: … 4-[(3R,4S)-4-(4-hydroxyphenyl)hexan-3-yl]phenol …
2-Phenethyl-2,3-Dihydro-Phthalazine-1,4-Dione
Experimental
Ruplizumab
Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.
Investigational
Displaying drugs 7051 - 7075 of 11962 in total