Displaying drugs 7176 - 7200 of 7928 in total
Cerdulatinib
Cerdulatinib is under investigation in clinical trial NCT04021082 (CELTIC-1: A Phase 2B Study of Cerdulatinib in Patients With Relapsed/refractory Peripheral T-cell Lymphoma (PTCL)).
Investigational
Matched Synonyms: … 4-(cyclopropylamino)-2-((4-(4-(ethanesulfonyl)piperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide ... 5-pyrimidinecarboxamide, 4-(cyclopropylamino)-2-((4-(4-(ethylsulfonyl)-1-piperazinyl)phenyl)amino)- …
Matched Iupac: … 4-(cyclopropylamino)-2-({4-[4-(ethanesulfonyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamide …
Matched Iupac: … 4-(cyclopropylamino)-2-({4-[4-(ethanesulfonyl)piperazin-1-yl]phenyl}amino)pyrimidine-5-carboxamide …
3-(Oxalyl-Amino)-Naphthalene-2-Carboxylic Acid
Experimental
Matched Name: … 3-(Oxalyl-Amino)-Naphthalene-2-Carboxylic Acid …
Matched Iupac: … 3-(carboxyformamido)naphthalene-2-carboxylic acid …
Matched Iupac: … 3-(carboxyformamido)naphthalene-2-carboxylic acid …
3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid
Experimental
Matched Name: … 3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid …
Matched Iupac: … 3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid …
Matched Iupac: … 3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid …
5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID
Experimental
Matched Name: … 5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID …
Matched Iupac: … 5-(dimethylamino)naphthalene-2-sulfonic acid …
Matched Iupac: … 5-(dimethylamino)naphthalene-2-sulfonic acid …
Valziflocept
Investigational
Matched Synonyms: … Human immunoglobulin gamma fc region receptor ii-b (fc.gamma.rii-b), extracellular n-terminal fragment …
Thymidine 5'-triphosphate
Experimental
Matched Synonyms: … 2'-deoxythymidine triphosphate …
Matched Iupac: … hydroxy({[hydroxy({[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2- …
Matched Iupac: … hydroxy({[hydroxy({[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2- …
Imolamine
Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3-phenyl-4,5-dihydro-1,2,3-oxadiazol,-4-yl)ethyl]amine. It is developed under the brand name Coremax by Novartis consumer health SA.
Investigational
Matched Iupac: … diethyl[2-(5-imino-3-phenyl-4,5-dihydro-1,2,4-oxadiazol-4-yl)ethyl]amine …
Matched Description: … Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3 …
Matched Description: … Imolamine is a compound with a molecular weight of 260.33 g/mol with the formula diethyl[2-{5-imino-3 …
Arginine PCA
Experimental
Matched Synonyms: … L-arginine L-2-pyrrolidone-5-carboxylate …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-5-oxopyrrolidine-2-carboxylic acid …
5-methoxy-N,N-dimethyltryptamine
5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a tryptamine with psychedelic properties. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad. This drug, as well as dimethyltryptamine and bufotenin, have been registered to be used in South America in religious and spiritual rituals.
Experimental
Illicit
Matched Synonyms: … 3-(2-dimethylaminoethyl)-5-methoxyindole ... 3-[2-(N,N-Dimethylamino)ethyl]-5-methoxy-indole …
Matched Iupac: … [2-(5-methoxy-1H-indol-3-yl)ethyl]dimethylamine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … [2-(5-methoxy-1H-indol-3-yl)ethyl]dimethylamine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Hycanthone
Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.
Experimental
Matched Synonyms: … 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one ... 1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)thioxanthen-9-one …
Matched Iupac: … 1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-9H-thioxanthen-9-one …
Matched Iupac: … 1-{[2-(diethylamino)ethyl]amino}-4-(hydroxymethyl)-9H-thioxanthen-9-one …
Izencitinib
Izencitinib is under investigation in clinical trial NCT03920254 (TD-1473 Long-term Safety (LTS) Ulcerative Colitis (UC) Study).
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Galegenimab
Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration (AMD)).
Investigational
Saruparib
Saruparib is under investigation in clinical trial NCT06380751 (Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in Hr-positive, Her2-negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or Palb2m Advanced Breast Cancer).
Investigational
Matched Synonyms: … 2-Pyridinecarboxamide, 5-[4-[(7-ethyl-5,6-dihydro-6-oxo-1,5-naphthyridin-3-yl)methyl]-1-piperazinyl]- ... 5-{4-[(7-ethyl-5,6-dihydro-6-oxo-1,5-naphthyridin-3- yl)methyl]piperazin-1-yl}-N-methylpyridine-2- carboxamide …
Matched Description: … CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in Hr-positive, Her2-negative (IHC 0, 1+, 2+ …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in Hr-positive, Her2-negative (IHC 0, 1+, 2+ …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Etryptamine
In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. αET was an FDA approved antidepressant under the name Monase. However, in 1962, after the discovery of an unacceptable incidence of agranulocytosis,...
Illicit
Investigational
Withdrawn
Matched Synonyms: … 3-(2-aminobutyl)indole …
Matched Iupac: … 1-(1H-indol-3-yl)butan-2-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 1-(1H-indol-3-yl)butan-2-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
WAY-151693
Experimental
Matched Synonyms: … N-Hydroxy-2-{[(4-methoxyphenyl)sulfonyl](3-pyridinylmethyl)amino}-3-methylbenzamide …
Matched Iupac: … N-hydroxy-3-methyl-2-{N-[(pyridin-3-yl)methyl]4-methoxybenzenesulfonamido}benzamide …
Matched Iupac: … N-hydroxy-3-methyl-2-{N-[(pyridin-3-yl)methyl]4-methoxybenzenesulfonamido}benzamide …
Istaroxime
Investigational
Matched Synonyms: … 3-((2-Aminoethoxy)imino)-5alpha-androstan-6,17-dione …
Matched Iupac: … (3aS,3bR,5aS,9aR,9bS,11aS)-7-[(2-aminoethoxy)imino]-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthrene …
Matched Iupac: … (3aS,3bR,5aS,9aR,9bS,11aS)-7-[(2-aminoethoxy)imino]-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthrene …
Ellagic acid
Ellagic acid is present in several fruits such as cranberries, strawberries, raspberries, and pomegranates. In pomegranates, there are several therapeutic compounds but ellagic acid is the most active and abundant. Ellagic acid is also present in vegetables. Ellagic acid is an investigational drug studied for treatment of Follicular Lymphoma (phase...
Investigational
Matched Description: … Ellagic acid is an investigational drug studied for treatment of Follicular Lymphoma (phase 2 trial), ... protection from brain injury of intrauterine growth restricted babies (phase 1 and 2 trial), improvement ... of cardiovascular function in adolescents who are obese (phase 2 trial), and topical treatment of solar …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Nepidermin
Experimental
Lucanthone
One of the schistosomicides, it has been replaced largely by hycanthone and more recently praziquantel. (From Martindale The Extrapharmacopoeia, 30th ed., p46). It is currently being tested as a radiation sensitizer.
Investigational
Matched Synonyms: … 1-((2-(Diethylamino)ethyl)amino)-4-methylthioxanthen-9-one ... 1-{[2-(diethylamino)ethyl]amino}-4-methylthioxanthen-9-one …
Matched Iupac: … 1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one …
Matched Salts cas: … 548-57-2 …
Matched Iupac: … 1-{[2-(diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one …
Matched Salts cas: … 548-57-2 …
Efavaleukin alfa
Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker. It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).
Investigational
Matched Synonyms: … Fc il-2 mutein fusion protein (amg-592) ... domain-containing fragment) fusion protein with peptide (synthetic linker) fusion protein with interleukin 2 …
Gunagratinib
Investigational
Matched Synonyms: … 1h-pyrazole-4-carboxamide, 3-(2-(3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1-((3s)-1-(1-oxo-2-propen …
Matched Iupac: … 3-[2-(3,5-dimethoxyphenyl)ethynyl]-5-(methylamino)-1-[(3S)-1-(prop-2-enoyl)pyrrolidin-3-yl]-1H-pyrazole …
Matched Iupac: … 3-[2-(3,5-dimethoxyphenyl)ethynyl]-5-(methylamino)-1-[(3S)-1-(prop-2-enoyl)pyrrolidin-3-yl]-1H-pyrazole …
Domvanalimab
Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell Lung Cancer).
Investigational
Irsenontrine
Irsenontrine is under investigation in clinical trial NCT03467152 (Study to Evaluate the Efficacy, Safety and Tolerability of E2027 (Hereinafter Referred to as Irsenontrine) in Participants With Dementia With Lewy Bodies).
Investigational
Matched Synonyms: … 4h-pyrazolo(4,3-c)quinolin-4-one, 1,5-dihydro-7-(2-methoxy-3,5-dimethyl-4- pyridinyl)-1-((3s)-tetrahydro ... 7-(2-methoxy-3,5-dimethylpyridin-4-yl)-1-((3s)-tetrahydrofuran-3-yl)-1,5-dihydro-4h-pyrazolo(4,3-c)quinolin …
4,5-Dihydroxy-Tetrahydro-Pyran-2-Carboxylic Acid
Experimental
Matched Name: … 4,5-Dihydroxy-Tetrahydro-Pyran-2-Carboxylic Acid …
Matched Iupac: … (2S,4S,5S)-4,5-dihydroxyoxane-2-carboxylic acid …
Matched Iupac: … (2S,4S,5S)-4,5-dihydroxyoxane-2-carboxylic acid …
alpha-D-glucopyranosyl-2-carboxylic acid amide
Experimental
Matched Name: … alpha-D-glucopyranosyl-2-carboxylic acid amide …
Matched Iupac: … (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-carboxamide …
Matched Iupac: … (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxane-2-carboxamide …
Displaying drugs 7176 - 7200 of 7928 in total