Displaying drugs 701 - 725 of 865 in total
LJP-538
Investigational
Matched Synonyms: … Human IgG1 anti-human cytomegalovirus monoclonal antibody LJP538 …
SAR-439459
SAR-439459 is a pan-transforming Growth Factor-beta (TGFβ) neutralizing antibody. Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis Imperfecta.
Investigational
Matched Synonyms: … ANTI-TGF-BETA MONOCLONAL ANTIBODY SAR-439459 …
Matched Description: … [A259862] Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis ... SAR-439459 is a pan-transforming Growth Factor-beta (TGFβ) neutralizing antibody. …
Matched Description: … [A259862] Developed by Sanofi, it is being investigated for the treatment of cancers and Osteogenesis ... SAR-439459 is a pan-transforming Growth Factor-beta (TGFβ) neutralizing antibody. …
Rocatinlimab
Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis. In clinical trials, it has shown significant efficacy and safety compared to a placebo. The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with atopic dermatitis. Despite...
Investigational
Matched Synonyms: … Anti-CD134 human monoclonal antibody (IgG1, KHK4083 dimer) …
Matched Description: … injection reactions such as fever and chills have been reported. ... In clinical trials, it has shown significant efficacy and safety compared to a placebo. ... Additionally, the diverse genetic backgrounds of patients may influence the drug’s effectiveness and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … injection reactions such as fever and chills have been reported. ... In clinical trials, it has shown significant efficacy and safety compared to a placebo. ... Additionally, the diverse genetic backgrounds of patients may influence the drug’s effectiveness and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vibecotamab
Vibecotamab is under investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure).
Investigational
Matched Synonyms: … Anti-cd123 x anti-cd3 bispecific antibody xmab14045 …
Matched Description: … investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and …
Matched Description: … investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and …
Ceftriaxone
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Description: … meninges[A215582], eyes[A215647], and inner ear[A215627]. ... [A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the ... Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins …
Matched Products: … Ceftriaxone and Dextrose …
Matched Products: … Ceftriaxone and Dextrose …
Glofitamab
Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively. It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting T-cells directly to the surface of cancerous B-cells.[L45698,A258488]
Glofitamab was approved...
Approved
Investigational
Matched Synonyms: … Anti-CD20/CD3 bispecific monoclonal antibody RO7082859 …
Matched Description: … Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface ... It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting ... antigens found on B- and T-cells, respectively. …
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface ... It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting ... antigens found on B- and T-cells, respectively. …
Matched Categories: … Monoclonal antibodies and antibody drug conjugates ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Lomvastomig
Lomvastomig is under investigation in clinical trial NCT04785820 (A Study of Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus).
Investigational
Matched Synonyms: … Anti-pd-1/tim-3 bispecific antibody ro7121661 …
Matched Description: … Lomvastomig is under investigation in clinical trial NCT04785820 (A Study of Lomvastomig (RO7121661) and …
Matched Description: … Lomvastomig is under investigation in clinical trial NCT04785820 (A Study of Lomvastomig (RO7121661) and …
RGX-121
RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the central nervous system.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus (AAV) vector of serotype 9 expressing human iduronate-2-sulfatase …
Matched Description: … RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the …
Matched Description: … RGX-121 is designed to use the NAV AAV9 vector to deliver the human iduronate-2-sulfatase gene to the …
ABBV-011
ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin.
Investigational
Matched Synonyms: … an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related …
Matched Description: … ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting …
Matched Description: … ABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting …
Panobacumab
Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA-101 in Hospital Acquired Pneumonia Caused by O11 Pseudomonas Aeruginosa).
Investigational
Matched Synonyms: … Human monoclonal antibody directed against serotype 011 Pseudomonas aeruginosa ... Human monoclonal antibody directed against serotype O1 Pseudomonas aeruginosa …
Matched Description: … Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA …
Matched Description: … Panobacumab is under investigation in clinical trial NCT00851435 (Safety and Pharmacokinetics of KBPA …
BI-836826
Investigational
Matched Synonyms: … ANTI-CD37 MONOCLONAL ANTIBODY BI 836826 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
DR-01
DR-01 is a monoclonal antibody directed against human CD94.
Investigational
Matched Synonyms: … Human anti-CD94 IgG1 monoclonal antibody (non-fucosylated) …
Matched Description: … DR-01 is a monoclonal antibody directed against human CD94. …
Matched Description: … DR-01 is a monoclonal antibody directed against human CD94. …
Human anti-il-6 monoclonal antibody (pf-04236921)
Human anti-il-6 monoclonal antibody (pf-04236921) is under investigation in clinical trial NCT01405196 (Subcutaneous Treatment in Randomized Subjects to Evaluate Safety and Efficacy in Generalized Lupus Erythematosus).
Investigational
Matched Synonyms: … HUMAN ANTI-IL-6 MONOCLONAL ANTIBODY (PF-04236921) …
Matched Name: … Human anti-il-6 monoclonal antibody (pf-04236921) …
Matched Description: … (Subcutaneous Treatment in Randomized Subjects to Evaluate Safety and Efficacy in Generalized Lupus ... Human anti-il-6 monoclonal antibody (pf-04236921) is under investigation in clinical trial NCT01405196 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Human anti-il-6 monoclonal antibody (pf-04236921) …
Matched Description: … (Subcutaneous Treatment in Randomized Subjects to Evaluate Safety and Efficacy in Generalized Lupus ... Human anti-il-6 monoclonal antibody (pf-04236921) is under investigation in clinical trial NCT01405196 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Cevostamab
Investigational
Matched Synonyms: … Anti-fcrh5/cd3 bite antibody bfcr4350a ... Fcrh5/cd3 t cell dependent bispecific antibody bfcr4350a ... Bfcr4350a (anti-fcrh5/cd3 t-cell dependent bispecific antibody) …
Bexmarilimab
Bexmarilimab is under investigation in clinical trial NCT03733990 (A Study to Evaluate Safety, Tolerability and Preliminary Efficacy of FP-1305 in Cancer Patients).
Investigational
Matched Synonyms: … Anti-clever-1 monoclonal antibody FP-1305 …
Matched Description: … Bexmarilimab is under investigation in clinical trial NCT03733990 (A Study to Evaluate Safety, Tolerability and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Bexmarilimab is under investigation in clinical trial NCT03733990 (A Study to Evaluate Safety, Tolerability and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Simtuzumab
Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis.
Investigational
Matched Synonyms: … Recombinant humanized anti-LOXL2 monoclonal antibody …
Matched Description: … Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis. ... Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Cancer, Colorectal Cancer, and Idiopathic Pulmonary Fibrosis. ... Simtuzumab has been used in trials studying the treatment and basic science of Myelofibrosis, Pancreatic …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tomaralimab
Tomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function).
Investigational
Matched Synonyms: … anti-Tlr2 monoclonal antibody OPN-305 ... Humanized IGG4 monoclonal antibody against toll-like receptor 2 for prevention of ischemia/reperfusion …
Matched Description: … under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
CR002
CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation. This is a novel therapeutic approach to treat kidney inflammation.
Investigational
Matched Synonyms: … Human monoclonal antibody against platelet-derived growth factor D …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …
RC118
RC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal antibody conjugated to MMAE.
Investigational
Matched Synonyms: … Recombinant humanized anti-MSLN monoclonal antibody- monomethyl auristatin E conjugate …
Matched Description: … antibody conjugated to MMAE. ... RC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal …
Matched Description: … antibody conjugated to MMAE. ... RC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal …
Sonelokimab
Sonelokimab is under investigation in clinical trial NCT06411379 (Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa).
Investigational
Matched Synonyms: … M-1095 (anti-interleukin (il)-17a/f single-domain antibody) …
Matched Description: … Sonelokimab is under investigation in clinical trial NCT06411379 (Study to Evaluate the Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Sonelokimab is under investigation in clinical trial NCT06411379 (Study to Evaluate the Efficacy and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Coltuximab ravtansine
Coltuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic leukemia (ALL).
Investigational
Matched Synonyms: … Anti-CD19 humanized monoclonal antibody conjugated to DM4 …
Matched Description: … Coltuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
Matched Description: … Coltuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antibody-drug Conjugates …
PAT-SM6
Investigational
Matched Synonyms: … Recombinant human monoclonal IgM antibody targeting glucose regulated protein 78 …
Ertumaxomab
Ertumaxomab is under investigation in clinical trial NCT00522457 (Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer After Progression on Trastuzumab Therapy).
Investigational
Matched Synonyms: … Anti-cd3 x anti-her-2-neu bispecific monoclonal antibody …
Matched Description: … Ertumaxomab is under investigation in clinical trial NCT00522457 (Phase II Study With the Trifunctional Antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Ertumaxomab is under investigation in clinical trial NCT00522457 (Phase II Study With the Trifunctional Antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
2-deoxy-2-acetamido-beta-D-galactose-4-sulfate
Experimental
Matched Name: … 2-deoxy-2-acetamido-beta-D-galactose-4-sulfate …
Ontamalimab
Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Investigational
Matched Synonyms: … human IgG2 monoclonal antibody directed against the mucosal addressin cell adhesion molecule ... human IgG2 anti-monoclonal antibody directed against mucosal addressin cell adhesion molecule (MAdCAM …
Matched Description: … Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 701 - 725 of 865 in total