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Displaying drugs 7326 - 7350 of 9012 in total
INCB13739
INCB13739 is developed as a new treatment for type 2 diabetes.
It is an orally available small molecule inhibitor of 11beta-HSD1 (11-beta hydroxysteroid dehydrogenase type 1). 11beta-HSD1 is an enzyme that appears to be critical to the development of type 2 diabetes.
Investigational
Matched Description: … orally available small molecule inhibitor of 11beta-HSD1 (11-beta hydroxysteroid dehydrogenase type 1) …
Matched Categories: … 11-beta-Hydroxysteroid Dehydrogenase Type 1, antagonists & inhibitors …
Matched Categories: … 11-beta-Hydroxysteroid Dehydrogenase Type 1, antagonists & inhibitors …
Clesacostat
Clesacostat is under investigation in clinical trial NCT04321031 (Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)).
Investigational
Matched Synonyms: … 4-(6-methoxy-4-(7-oxo-1-(propan-2-yl)-1,4,6,7-tetrahydrospiro(indazole-5,4'- piperidine)-1'-carbonyl) ... )-1'-yl)carbonyl)-2-pyridinyl)- ... Benzoic acid, 4-(6-methoxy-4-((1,4,6,7-tetrahydro-1-(1-methylethyl)-7-oxospiro(5h-indazole-5,4'-piperidin …
Zomepirac
Zomepirac, formerly marketed as Zomax tablets, was associated with fatal and near-fatal anaphylactoid reactions. The manufacturer voluntarily removed Zomax tablets from the Canadian, US, and UK markets in March 1983.
Withdrawn
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pateclizumab
Pateclizumab is under investigation in clinical trial NCT01225393 (A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared With Adalimumab in Combination With a DMARD in Patients With Active Rheumatoid Arthritis).
Investigational
Agatolimod
Agatolimod is under investigation in clinical trial NCT00471471 (Vaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery).
Investigational
Zebularine
A chemically stable, cytidine analog that displays anti-tumor properties. It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates. Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo.
Experimental
Matched Synonyms: … 1-beta-D-ribofuranosyl-2(1H)-pyrimidinone ... 1-beta-D-ribofuranosylpyrimidin-2(1H)-one …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
S-Apomorphine
Investigational
Matched Iupac: … (9S)-10-methyl-10-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(17),2(7),3,5,13,15-hexaene-3,4-diol …
N-[4-hydroxymethyl-cyclohexan-6-yl-1,2,3-triol]-4,6-dideoxy-4-aminoglucopyranoside
Experimental
Matched Iupac: … (2S,3R,4S,5S,6R)-6-methyl-5-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino …
4-Bromo-3-(5'-Carboxy-4'-Chloro-2'-Fluorophenyl)-1-Methyl-5-Trifluoromethyl-Pyrazol
Experimental
Matched Name: … 4-Bromo-3-(5'-Carboxy-4'-Chloro-2'-Fluorophenyl)-1-Methyl-5-Trifluoromethyl-Pyrazol …
Matched Iupac: … 5-[4-bromo-1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]-2-chloro-4-fluorobenzoic acid …
Matched Iupac: … 5-[4-bromo-1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]-2-chloro-4-fluorobenzoic acid …
2,3-Dicarboxy-4-(2-Chloro-Phenyl)-1-Ethyl-5-Isopropoxycarbonyl-6-Methyl-Pyridinium
Experimental
Matched Name: … 2,3-Dicarboxy-4-(2-Chloro-Phenyl)-1-Ethyl-5-Isopropoxycarbonyl-6-Methyl-Pyridinium …
Matched Iupac: … 2,3-dicarboxy-4-(2-chlorophenyl)-1-ethyl-6-methyl-5-[(propan-2-yloxy)carbonyl]pyridin-1-ium …
Matched Iupac: … 2,3-dicarboxy-4-(2-chlorophenyl)-1-ethyl-6-methyl-5-[(propan-2-yloxy)carbonyl]pyridin-1-ium …
[[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER
Experimental
Matched Name: … [[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER …
Matched Iupac: … ethyl (2S)-2-[(2S)-2-[(2R)-3-(hydroxycarbamoyl)-2-(2-methylpropyl)propanamido]-4-methylpentanamido]propanoate …
Matched Iupac: … ethyl (2S)-2-[(2S)-2-[(2R)-3-(hydroxycarbamoyl)-2-(2-methylpropyl)propanamido]-4-methylpentanamido]propanoate …
3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID
Experimental
Matched Name: … 3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID …
Matched Iupac: … 3-(carboxymethoxy)thieno[2,3-b]pyridine-2-carboxylic acid …
Matched Iupac: … 3-(carboxymethoxy)thieno[2,3-b]pyridine-2-carboxylic acid …
2,3-Anhydro-quinic acid
Experimental
Matched Iupac: … (1R,4R,5R)-1,4,5-trihydroxycyclohex-2-ene-1-carboxylic acid …
3-Cyclohexyl-L-alanine
Experimental
Matched Name: … 3-Cyclohexyl-L-alanine …
Matched Iupac: … (2S)-2-amino-3-cyclohexylpropanoic acid …
Matched Iupac: … (2S)-2-amino-3-cyclohexylpropanoic acid …
3-Isopropylmalic Acid
Experimental
Matched Name: … 3-Isopropylmalic Acid …
Matched Iupac: … 2-hydroxy-3-(propan-2-yl)butanedioic acid …
Matched Iupac: … 2-hydroxy-3-(propan-2-yl)butanedioic acid …
Shikimate-3-Phosphate
Experimental
Matched Name: … Shikimate-3-Phosphate …
Matched Iupac: … (3R,4S,5R)-4,5-dihydroxy-3-(phosphonooxy)cyclohex-1-ene-1-carboxylic acid …
Matched Iupac: … (3R,4S,5R)-4,5-dihydroxy-3-(phosphonooxy)cyclohex-1-ene-1-carboxylic acid …
Sagopilone
Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is the first such compound to be in clinical development to combat several forms of cancer. Epothilones are 16-member ring macrolides...
Investigational
Matched Iupac: … (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,12,16-tetramethyl-3-(2-methyl-1,3-benzothiazol-5-yl)-10 ... -(prop-2-en-1-yl)-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Hydracrylic acid
Experimental
Matched Synonyms: … 3-Hydroxypropanoic acid ... 3-Hydroxypropionic acid …
Matched Iupac: … 3-hydroxypropanoic acid …
Matched Iupac: … 3-hydroxypropanoic acid …
SGS-742
SGS-742 has been used in trials studying the treatment of Seizures and Metabolic Disease.
Investigational
Matched Synonyms: … 3-Aminopropyl-Butyl Phosphinic Acid ... (3-Aminopropyl)(n-butyl)phosphinic acid …
Matched Iupac: … (3-aminopropyl)(butyl)phosphinic acid …
Matched Iupac: … (3-aminopropyl)(butyl)phosphinic acid …
Darleukin
Investigational
Recombinant human palmitoyl-protein thioesterase-1
Investigational
Matched Synonyms: … Recombinant human palmitoyl-protein thioeserase-1 ... RECOMBINANT HUMAN PALMITOYL-PROTEIN THIOESERASE-1 (RHPPT1) …
Matched Name: … Recombinant human palmitoyl-protein thioesterase-1 …
Matched Name: … Recombinant human palmitoyl-protein thioesterase-1 …
Recilisib
Investigational
(2E)-3-(2,4-DICHLOROPHENYL)-N-HYDROXYACRYLAMIDE
Experimental
Matched Name: … (2E)-3-(2,4-DICHLOROPHENYL)-N-HYDROXYACRYLAMIDE …
Matched Iupac: … (2E)-3-(2,4-dichlorophenyl)-N-hydroxyprop-2-enamide …
Matched Iupac: … (2E)-3-(2,4-dichlorophenyl)-N-hydroxyprop-2-enamide …
Dapaconazole
Dapaconazole has been used in trials studying the treatment of Tinea Pedis.
Investigational
Matched Iupac: … 1-[2-(2,4-dichlorophenyl)-2-{[4-(trifluoromethyl)phenyl]methoxy}ethyl]-1H-imidazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Letrazuril
Letrazuril has been used in trials studying the treatment of HIV Infections and Cryptosporidiosis.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 7326 - 7350 of 9012 in total