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Displaying drugs 726 - 750 of 950 in total

Cobimetinib

Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction pathway. It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of patients with unresectable or...
Approved
Investigational
Matched Description: … Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated ... protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction ... It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … COTELLIC 20 MG FILM KAPLI TABLET,63 FILM KAPLI TABLET ... COTELLIC FILM-COATED TABLET 20 MG ... COTELLIC FILM COATED TABLET 20MG …

Cilazapril

Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Description: … It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries ... Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. …
Matched Mixtures name: … ACEPRIX PLUS 5 MG/12.5 MG FILM TABLET, 30 ADET ... İNHİBACE PLUS 5 MG/12,5 MG FILM KAPLI TABLET, 28 ADET …
Matched Categories: … ACE Inhibitors and Diuretics ... cilazapril and diuretics …
Matched Products: … ACEPRIX 1 MG FILM TABLET, 30 ADET ... ACEPRIX 5 MG FILM TABLET, 30 ADET ... ACEPRIX 2.5 MG FILM TABLET, 30 ADET …

Letermovir

Letermovir recieved approval from the FDA on November 8th, 2017 for use in prophylaxis of cytomegalovirus (CMV) infection in allogeneic hematopoietic stem cell transplant patients. It is the first of a new class of CMV anti-infectives called DNA terminase complex inhibitors. Letermovir has recieved both priority and orphan drug status...
Approved
Investigational
Matched Description: … [A31290] Letermovir has recieved both priority and orphan drug status from the FDA. …
Matched Products: … PREVYMIS FILM COATED TABLET 240MG ... PREVYMIS FILM COATED TABLET 480MG ... PREVYMIS 240MG FILM-COATED TABLET …

Voriconazole

Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase...
Approved
Matched Description: … These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. ... [L15571] It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised …
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … VFEND FILM-COATED TABLET 50 mg ... VFEND FILM-COATED TABLET 200 mg ... VFEND 50 MG FILM TABLET, 14 ADET …

Tucatinib

Tucatinib is a kinase inhibitor drug used with trastuzumab and capecitabine in the treatment of unresectable or metastatic HER-2 positive breast cancer. It was developed by Seattle Genetics and approved by the FDA on April 17, 2020. Tucatinib is a promising new treatment for patients with metastatic breast cancer who...
Approved
Investigational
Matched Description: … It was developed by Seattle Genetics and approved by the FDA on April 17, 2020. ... Tucatinib is a kinase inhibitor drug used with [trastuzumab] and [capecitabine] in the treatment of unresectable ... [L12951] Tucatinib is a promising new treatment for patients with metastatic breast cancer who have not …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … TUKYSA 50 mg film-coated tablets ... TUKYSA 150 mg film-coated tablets ... TUKYSA (TUCATINIB) FILM-COATED TABLETS 150 mg …

Bosutinib

Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Description: … Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine ... BCR-ABL inhibitors like bosutinib inhibit most resistance-conferring BCR-ABL mutations except V299L and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BOSULİF 500 MG FİLM KAPLI TABLET, 28 ADET ... BOSULİF 500 MG FİLM KAPLI TABLET, 30 ADET ... BOSULİF 100 MG FİLM KAPLI TABLET, 28 ADET …

Capecitabine

Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Approved
Investigational
Matched Description: … Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and ... enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Fluorouracil and prodrugs ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … KAPETRAL FILM-COATED TABLET 500MG ... KAPETRAL FILM-COATED TABLET 150MG ... XELODA (500 MG FILM-COATED TABLETS) …

Trimetazidine

Trimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies. Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s.[A233255,A233260] Acidic conditions, caused by anaerobic metabolism and fatty acid oxidation, in response...
Approved
Investigational
Matched Description: … to myocardial ischemia, activate sodium-hydrogen and sodium-calcium antiport systems. ... [A233255,A233260] Acidic conditions, caused by anaerobic metabolism and fatty acid oxidation, in response …
Matched Products: … SITOREL MR 35 MG DEĞIŞTIRILMIŞ SALIMLI FILM TABLET,FILM TABLET, 60 ADET ... SITOREL 20 MG FILM TABLET, 60 ADET ... VASOFIX 20 MG FILM TABLET, 60 ADET …

Ramelteon

Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.
Approved
Investigational
Matched Description: … Ramelteon has not been shown to produce dependence and has shown no potential for abuse. …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … RAMELDA 8 MG FILM KAPLI TABLET,30 ADET ... RAMELDA 8 MG FILM KAPLI TABLET,10 ADET ... ROZEREST 8 MG FİLM KAPLI TABLET, 10 ADET …

Daclatasvir

Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. It is marketed under the name DAKLINZA and is contained in daily oral tablets as the hydrochloride salt form . Hepatitis C is an infectious liver disease...
Approved
Investigational
Matched Description: … Combination therapies that include daclatasir can be used for challenging-to-treat patients who have ... daclatasvir and [DB08934] therapy were 88% and 99%, respectively [FDA Label]. ... Daclatasvir is shown to target both the cis- and trans-acting functions of NS5A and disrupts the function …
Matched Categories: … Amino Acids, Peptides, and Proteins ... daclatasvir, asunaprevir and beclabuvir …
Matched Products: … DAKLINZA 30 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 28 ADET ... DAKLINZA 60 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 28 ADET ... Daclavir 60mg Film Coated Tablet …

Canagliflozin

Canagliflozin, also known as Invokana, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise [FDA label]. It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018...
Approved
Matched Description: … inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and ... It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 …
Matched Mixtures name: … FILM-COATED TABLETS 50 MG / 1000 MG ... FILM-COATED TABLETS 50 MG / 500 MG ... FILM-COATED TABLETS 150 MG / 500 MG …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and canagliflozin …
Matched Products: … FILM-COATED TABLETS 100 MG ... FILM-COATED TABLETS 300 MG ... Invokana 300mg Film-Coated Tablets …

Montelukast

Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Description: … others in individuals who used the medication. ... has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and …
Matched Mixtures name: … LORCLAST 5 MG/10 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 30 ADET ... DESMONT 5/10 MG 90 FILM KAPLI TABLET ... LEPIXOS 5 MG/10 MG FILM TABLET ,30 ADET …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SINAIR 10 MG FILM KAPLI TABLET ,FILM TABLET, 28 ADET ... OXAIR FILM COATED TABLET 10MG ... AIRMOL 10 MG FILM TABLET, 56 ADET …

Deferiprone

Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired....
Approved
Matched Products: … FERRIPROX FILM-COATED TABLET 500 mg ... Ferriprox 1000mg Film-Coated Tablet ... HİERO 500 MG FİLM KAPLI TABLET, 100 ADET …

Nalmefene

Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Description: … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist …
Matched Products: … SELINCRO 18MG FILM KAPLI TABLET ,42 TABLET ... SELINCRO 18MG FILM KAPLI TABLET ,7 TABLET ... SELINCRO 18MG FILM KAPLI TABLET ,TABLET, 28 ADET …

Teriflunomide

Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. The FDA label states an important warning about the risk of hepatoxicity and...
Approved
Matched Description: … Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting ... It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically ... The FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Matched Products: … AUBAGIO FILM-COATED TABLETS 14mg ... AUBAGIO 14mg Film-coated Tablets ... AVORAN 14 MG FİLM KAPLI TABLET, 28 ADET …

Risperidone

Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). Schizophrenia and...
Approved
Investigational
Matched Description: … D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical ... mental health conditions including schizophrenia and bipolar disorder. ... Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and …
Matched Products: … RISPERIDON - CT 0.5MG FILM ... WELRIS 1 MG FİLM TABLET, 30 ADET ... WELRIS 1 MG FİLM TABLET, 60 ADET …

Famciclovir

Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Approved
Investigational
Matched Categories: … Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Products: … FAMVIR 250 MG FILM TABLET, 21 ADET ... VIRMOL 125 MG FILM KAPLI TABLET, 14 ADET ... VIRMOL 500 MG FILM KAPLI TABLET, 14 ADET …

Ponatinib

Ponatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ICLUSIG FILM-COATED TABLET 45 MG ... ICLUSIG FILM-COATED TABLET 15 MG ... ICLUSIG 15 MG FILM-COATED TABLETS …

Lorlatinib

Lorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer which was first approved by the US FDA in November of 2018. It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously treated advanced ALK-positive...
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … LORVIQUA FILM-COATED TABLET 25MG ... LORVIQUA FILM-COATED TABLET 100MG ... Lorviqua 25 mg Film-Coated Tablets …

Varenicline

Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Matched Description: … Chantix, has been associated with seizures and that some patients who drink while taking the drug may ... In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. ... Food and Drug Administration warned that Varenicline, in the form of Pfizer Inc's quit-smoking drug, …
Matched Mixtures name: … CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET ... CHAMPIX 0,5 MG 1 MG FILM KAPLI TABLET, 11 VE 14 ADET ... CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLET …
Matched Products: … CHAMPIX 0.5MG FILM-COATED TABLETS ... CHAMPIX 1.0MG FILM-COATED TABLETS ... CHAMPIX 1 MG FILM KAPLI TABLET, 28 ADET …

Vardenafil

Vardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction.[L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the...
Approved
Matched Description: … selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and ... cells in the corpus cavernosum, activating the enzyme guanylate cyclase and increasing the synthesis ... [L45563,L45568] During sexual stimulation, nitric oxide (NO) is released from nerve endings and endothelial …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … VAREKSİL 5 MG FİLM KAPLI TABLET, 4 ADET ... VAREKSİL 10 MG FİLM KAPLI TABLET, 4 ADET ... VAREKSİL 20 MG FİLM KAPLI TABLET, 2 ADET …

Lercanidipine

Lercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Approved
Investigational
Matched Mixtures name: … ZANITEK 10 MG/10MG FILM TABLET,90 ADET ... ZANITEK 10 MG/10MG FILM TABLET, 30 ADET ... ZANITEK 20 MG/10MG FILM TABLET, 30 ADET …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... Calcium-Regulating Hormones and Agents ... valsartan and lercanidipine ... enalapril and lercanidipine ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Matched Products: … ZANIDIP 10MG FILM COATED TABLETS ... Zanidip 20mg, film-coated tablet ... LERCADIP 10 MG FILM TABLET, 30 ADET …

Lacosamide

Lacosamide is an antiepileptic drug used to treat seizures. As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents. Lacosamide exhibits a stereoselective mode of interaction with sodium channels. Lacosamide was first approved by the European Commission in August 2008 and was later...
Approved
Matched Description: … [A262681] Lacosamide was first approved by the European Commission in August 2008 and was later approved …
Matched Products: … VIMPAT 50 MG (FILM-COATED TABLETS) ... VIMPAT 100 MG (FILM-COATED TABLETS) ... BENVIDA 50 MG FILM KAPLI TABLET, 14 ADET …

Osimertinib

Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Description: … where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing and ... Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs ... [A7927] More specifically, deletions around the LREA motif in exon 19 and exon 21 L858R point mutations …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Tagrisso Film-Coated Tablet 40mg ... Tagrisso Film-Coated Tablet 80mg ... TAGRİSSO 40 MG FİLM KAPLI TABLET …

Fimasartan

Fimasartan is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials. Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the...
Investigational
Matched Description: … is an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and ... Fimasartan was initially approved September 9th, 2010 in South Korea and is marketed under the brand …
Matched Categories: … fimasartan and diuretics ... fimasartan and amlodipine ... rosuvastatin and fimasartan ... Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers …
Matched Products: … Kanarb Film-Coated Tablets 60mg ... Kanarb Film-Coated Tablets 120mg ... KANARB®PLUS FILM COATED TABLETS 60 MG/12.5 MG …
Displaying drugs 726 - 750 of 950 in total