Displaying drugs 726 - 750 of 1239 in total
Volrubigene ralaparvovec
Volrubigene ralaparvovec is under investigation in clinical trial NCT03223194 (Gene Transfer Clinical Study in Crigler-najjar Syndrome).
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated viral vector, serotype 8, expressing the 1A1 isoform of …
Matched Categories: … Adeno-associated Viral Vector Therapies …
Matched Categories: … Adeno-associated Viral Vector Therapies …
Favipiravir
Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza.[A191688,A191721] The antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and replication of viral genomes.[A191688,A191772,A191775]
Not only does favipiravir inhibit...
Approved
Investigational
Matched Description: … , Lassa virus, and now COVID-19. ... [A191688,A191772,A191775]
Not only does favipiravir inhibit replication of influenza A and B, but ... the drug has shown promise in the treatment of avian influenza, and may be an alternative option for …
Matched Products: … L-VIR …
Matched Products: … L-VIR …
Mentha arvensis top
Mentha arvensis top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Japanese Mint Top …
Etodolac
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Synonyms: … (±)-1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid ... 1,3,4,9-tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid ... 1,8-diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid …
Matched Iupac: … 2-{1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl}acetic acid …
Matched Description: … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. ... Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Iupac: … 2-{1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl}acetic acid …
Matched Description: … It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis. ... Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Pheneticillin
Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally.
Approved
Matched Synonyms: … penicillin B …
Human adenovirus b serotype 7
Human adenovirus b serotype 7 is a vaccine.
Approved
Matched Synonyms: … Human Adenovirus B Serotype 7 Strain 55142 …
Matched Name: … Human adenovirus b serotype 7 …
Matched Description: … Human adenovirus b serotype 7 is a vaccine. …
Matched Name: … Human adenovirus b serotype 7 …
Matched Description: … Human adenovirus b serotype 7 is a vaccine. …
Zileuton
Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and eosinophil migration, neutrophil and monocyte aggregation, leukocyte adhesion, increased capillary permeability, and smooth muscle contraction. These effects contribute to inflammation, edema, mucus secretion, and bronchoconstriction in the airways of asthmatic patients. Zileuton relieves such symptoms through its...
Approved
Investigational
Withdrawn
Matched Synonyms: … N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea ... (±)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea ... N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea …
Matched Description: … , and smooth muscle contraction. ... Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and ... Specifically, it inhibits leukotriene LTB4, LTC4, LTD4, and LTE4 formation. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … , and smooth muscle contraction. ... Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and ... Specifically, it inhibits leukotriene LTB4, LTC4, LTD4, and LTE4 formation. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Carbopol 974P
Carbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of pathogens. It was under development by ReProtect LLC. It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies. The compound,...
Investigational
Matched Synonyms: … Carbomer homopolymer type B ... Carbomer homopolymer type B (allyl pentaerythritol crosslinked) …
Matched Description: … It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted ... It was under development by ReProtect LLC. ... compound, known as BufferGel, was in advanced clinical trials for its ability to prevent pregnancy, but …
Matched Description: … It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted ... It was under development by ReProtect LLC. ... compound, known as BufferGel, was in advanced clinical trials for its ability to prevent pregnancy, but …
6-fluoro-9-methyl-9H-pyrido(3,4-B)-indole
Investigational
Matched Synonyms: … 6-fluoro-9-methyl-9H-pyrido[3,4-b]-indole …
Matched Name: … 6-fluoro-9-methyl-9H-pyrido(3,4-B)-indole …
Matched Iupac: … 6-fluoro-9-methyl-9H-pyrido[3,4-b]indole …
Matched Name: … 6-fluoro-9-methyl-9H-pyrido(3,4-B)-indole …
Matched Iupac: … 6-fluoro-9-methyl-9H-pyrido[3,4-b]indole …
Aeruginosin 98-B
Experimental
Matched Name: … Aeruginosin 98-B …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tricyclazole
Experimental
Investigational
Matched Synonyms: … 5-methyl-1,2,4-triazolo(3,4-b)benzothiazole ... 5-methyl-1,2,4-triazolo(3,4-b)(1,3)benzothiazole …
Adenovirus type 7 vaccine live
Approved
Matched Synonyms: … Human adenovirus B serotype 7 strain 55142 antigen …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Viral Vaccines …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Viral Vaccines …
Betadex
Experimental
Matched Synonyms: … Cyclodextrin B …
Matched Categories: … Diet, Food, and Nutrition …
Matched Categories: … Diet, Food, and Nutrition …
Recombinant stabilized RSV B prefusion F antigen
Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. The vaccine comprises two antigens - the other being recombinant stabilized RSV A prefusion F antigen - which have been expressed in Chinese hamster ovary cell lines and then purified...
Approved
Matched Synonyms: … RSV subgroup B stabilized prefusion F protein …
Matched Name: … Recombinant stabilized RSV B prefusion F antigen …
Matched Description: … [L48066] Abrysvo was first approved by the FDA in May 2023 for use in patients ≥60 years of age, and ... virus (RSV) vaccine called Abrysvo. ... then purified and lyophilized. …
Matched Categories: … Viral Vaccines ... Respiratory syncytial virus (RSV) vaccines …
Matched Name: … Recombinant stabilized RSV B prefusion F antigen …
Matched Description: … [L48066] Abrysvo was first approved by the FDA in May 2023 for use in patients ≥60 years of age, and ... virus (RSV) vaccine called Abrysvo. ... then purified and lyophilized. …
Matched Categories: … Viral Vaccines ... Respiratory syncytial virus (RSV) vaccines …
SN-38
7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan DB00762, a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer. SN 38 has been used in trials studying the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and Triple Negative...
Investigational
Matched Synonyms: … IRINOTECAN RELATED COMPOUND B ... 1H-PYRANO(3',4':6,7)INDOLIZINO(1,2-B)QUINOLINE-3,14(4H,12H)-DIONE, 4,11-DIETHYL-4,9-DIHYDROXY-, (4S)- …
Matched Description: … the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and …
Matched Description: … the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and …
Tobramycin
Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Synonyms: … 3'-Deoxykanamycin B …
Matched Description: … [A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to ... in a variety of forms for administration by inhalation, injection, and external application to the eye ... [A232294, A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available …
Matched Mixtures name: … Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone …
Matched Products: … TOBRAMICINA B. BRAUN ... Tobramycin B. Braun 1 mg/ml Infusionslösung ... Tobramycin B. Braun 3 mg/ml Infusionslösung …
Matched Description: … [A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to ... in a variety of forms for administration by inhalation, injection, and external application to the eye ... [A232294, A232349, L32739, L32749] Tobramycin was approved by the FDA in 1975 and is currently available …
Matched Mixtures name: … Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone …
Matched Products: … TOBRAMICINA B. BRAUN ... Tobramycin B. Braun 1 mg/ml Infusionslösung ... Tobramycin B. Braun 3 mg/ml Infusionslösung …
Fenofibrate
Fenofibrate is a fibric acid derivative like clofibrate and gemfibrozil. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591]
Fenofibrate was granted FDA approval on 31 December 1993.
Approved
Matched Description: … Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil]. …
Matched Categories: … pravastatin and fenofibrate ... simvastatin and fenofibrate ... rosuvastatin and fenofibrate ... pravastatin, ezetimibe and fenofibrate …
Matched Products: … Aa-feno-micro ... Lipidil Micro ... Feno-micro-200 …
Matched Categories: … pravastatin and fenofibrate ... simvastatin and fenofibrate ... rosuvastatin and fenofibrate ... pravastatin, ezetimibe and fenofibrate …
Matched Products: … Aa-feno-micro ... Lipidil Micro ... Feno-micro-200 …
Pittsburgh Compound B
Pittsburgh Compound B is under investigation in clinical trial NCT01723553 (Amyloid-related Imaging Abnormalities (Microbleeds) in Atypical AD).
Investigational
Matched Name: … Pittsburgh Compound B …
Matched Description: … Pittsburgh Compound B is under investigation in clinical trial NCT01723553 (Amyloid-related Imaging Abnormalities …
Matched Description: … Pittsburgh Compound B is under investigation in clinical trial NCT01723553 (Amyloid-related Imaging Abnormalities …
Flumazenil
Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
Approved
Matched Description: … Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that …
Matched Products: … FLUMAZENIL B. BRAUN ... Flumazenil B. Braun 0,1 mg/ml Injektionslösung und Konzentrat zur Herstellung einer Infusionslösung …
Matched Products: … FLUMAZENIL B. BRAUN ... Flumazenil B. Braun 0,1 mg/ml Injektionslösung und Konzentrat zur Herstellung einer Infusionslösung …
Influenza A virus A/Michigan/45/2015 (H1N1) recombinant hemagglutinin antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Michigan/45/2015 (H1N1) recombinant hemagglutinin antigen …
Matched Description: … Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Matched Description: … Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Influenza A virus A/Slovenia/2903/2015 (H1N1) live (attenuated) antigen
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Slovenia/2903/2015 (H1N1) live (attenuated) antigen …
Matched Description: … Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Matched Description: … Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Influenza A virus A/Uruguay/716/2007(H3N2) antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Uruguay/716/2007(H3N2) antigen (propiolactone inactivated) …
Matched Description: … Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Matched Categories: … Viral Vaccines ... Inactivated Influenza A Virus Vaccine …
Matched Description: … Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised …
Matched Categories: … Viral Vaccines ... Inactivated Influenza A Virus Vaccine …
Displaying drugs 726 - 750 of 1239 in total