Displaying drugs 726 - 750 of 2795 in total
Oteracil
Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with DB09257 and DB09256 within the commercially available product "Teysuno". The main active ingredient in Teysuno is DB09256,...
Approved
Matched Synonyms: … Oxonic Acid ... 5-azaorotic acid ... Allantoxanic acid …
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid …
Matched Description: … European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with [DB09257] and ... , and therefore reduce's gastrointestinal toxicity [L933]. ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, …
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid …
Matched Description: … European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with [DB09257] and ... , and therefore reduce's gastrointestinal toxicity [L933]. ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, …
Madecassic acid
Experimental
Matched Synonyms: … Brahmic acid ... 6β-hydroxyasiatic acid …
Matched Name: … Madecassic acid …
Matched Iupac: … 9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid …
Matched Name: … Madecassic acid …
Matched Iupac: … 9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid …
gamma-Hydroxybutyric acid
Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple countries. It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. However, it is important to note that GHB is a designated Orphan drug (in 1985). Today Xyrem is...
Approved
Illicit
Investigational
Matched Synonyms: … 3-carboxypropoxy acid ... 4-hydroxy-butyric acid ... oxy-n-butyric acid …
Matched Name: … gamma-Hydroxybutyric acid …
Matched Iupac: … 4-hydroxybutanoic acid …
Matched Description: … Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple ... It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Hydroxy Acids ... Fatty Acids, Volatile …
Matched Name: … gamma-Hydroxybutyric acid …
Matched Iupac: … 4-hydroxybutanoic acid …
Matched Description: … Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple ... It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Hydroxy Acids ... Fatty Acids, Volatile …
5-aminonaphthalene-2-sulfonic acid
Experimental
Matched Synonyms: … 1,6-Cleve's acid ... Cleve's β-acid ... 1-naphthylamine-6-sulfonic acid …
Matched Name: … 5-aminonaphthalene-2-sulfonic acid …
Matched Iupac: … 5-aminonaphthalene-2-sulfonic acid …
Matched Name: … 5-aminonaphthalene-2-sulfonic acid …
Matched Iupac: … 5-aminonaphthalene-2-sulfonic acid …
Phenylbutyric acid
Phenylbutyric acid is a fatty acid and a derivative of butyric acid naturally produced by colonic bacteria fermentation. It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
Approved
Investigational
Matched Synonyms: … 4-Phenyl-n-butyric acid ... 4-phenylbutyric acid ... Benzenebutyric acid …
Matched Name: … Phenylbutyric acid …
Matched Iupac: … 4-phenylbutanoic acid …
Matched Description: … Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... sodium phenylbutyrate and ursodoxicoltaurine …
Matched Name: … Phenylbutyric acid …
Matched Iupac: … 4-phenylbutanoic acid …
Matched Description: … Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... sodium phenylbutyrate and ursodoxicoltaurine …
Cyclohexanepropanoic acid
Experimental
Matched Synonyms: … 3-Cyclohexanepropionic acid ... 3-Cyclohexylpropanoic acid ... 3-Cyclohexylpropionic acid …
Matched Name: … Cyclohexanepropanoic acid …
Matched Iupac: … 3-cyclohexylpropanoic acid …
Matched Name: … Cyclohexanepropanoic acid …
Matched Iupac: … 3-cyclohexylpropanoic acid …
Salicylamide O-acetic acid
Experimental
Matched Synonyms: … Salamidacetic acid ... 2-Carbamoylphenoxyacetic acid ... Salicylamide-2-acetic acid …
Matched Name: … Salicylamide O-acetic acid …
Matched Iupac: … 2-(2-carbamoylphenoxy)acetic acid …
Matched Name: … Salicylamide O-acetic acid …
Matched Iupac: … 2-(2-carbamoylphenoxy)acetic acid …
Caprylhydroxamic acid
Experimental
Matched Synonyms: … Caprylohydroxamic acid ... Octanohydroxamic acid ... Octanoylhydroxamic acid …
Matched Name: … Caprylhydroxamic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Matched Name: … Caprylhydroxamic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Nitarsone
Nitarsone is an organoarsenic compound. It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing blackhead disease. It is marketed as Histostat by Zoetis, a publicly traded subsidiary of Pfizer.
Vet approved
Matched Synonyms: … (p-nitrophenyl)arsonic acid ... 4-nitrobenzenearsonic acid ... 4-nitrophenylarsonic acid …
Matched Iupac: … (4-nitrophenyl)arsonic acid …
Matched Description: … It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing …
Matched Iupac: … (4-nitrophenyl)arsonic acid …
Matched Description: … It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing …
3-phenylpropionic acid
Experimental
Matched Synonyms: … 3-phenyl-propionic acid ... 3-phenylpropanoic acid ... Hydrocinnamic acid …
Matched Name: … 3-phenylpropionic acid …
Matched Iupac: … 3-phenylpropanoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … 3-phenylpropionic acid …
Matched Iupac: … 3-phenylpropanoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
L-2-aminopimelic acid
Experimental
Matched Synonyms: … 2-Aminopimelic acid ... L-α-aminopimelic acid ... (2S)-2-Aminoheptanedioic acid …
Matched Name: … L-2-aminopimelic acid …
Matched Iupac: … (2S)-2-aminoheptanedioic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … L-2-aminopimelic acid …
Matched Iupac: … (2S)-2-aminoheptanedioic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Clesacostat
Clesacostat is under investigation in clinical trial NCT04321031 (Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)).
Investigational
Matched Synonyms: … Benzoic acid, 4-(6-methoxy-4-((1,4,6,7-tetrahydro-1-(1-methylethyl)-7-oxospiro(5h-indazole-5,4'-piperidin ... pyridin-2-yl)benzoic acid ... 4-(6-methoxy-4-(7-oxo-1-(propan-2-yl)-1,4,6,7-tetrahydrospiro(indazole-5,4'- piperidine)-1'-carbonyl) …
(S)-3-phenyllactic acid
Experimental
Matched Synonyms: … L-3-phenyllactic acid ... L-β-phenyllactic acid ... L-(−)-3-phenyllactic acid …
Matched Name: … (S)-3-phenyllactic acid …
Matched Iupac: … (2S)-2-hydroxy-3-phenylpropanoic acid …
Matched Name: … (S)-3-phenyllactic acid …
Matched Iupac: … (2S)-2-hydroxy-3-phenylpropanoic acid …
Pidolic acid
Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various chemical pathways [A32991, L2729]. Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism...
Approved
Investigational
Matched Synonyms: … Glutimic acid ... Pidolic acid ... (S)-pyroglutamic acid …
Matched Name: … Pidolic acid …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Description: … Pidolic acid, in general, is found in large quantities in brain tissue and other tissues in bound form ... or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various ... or memory enhancement, most available research suggest exercising caution in their recommendation as much …
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids ... Imino Acids …
Matched Name: … Pidolic acid …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Description: … Pidolic acid, in general, is found in large quantities in brain tissue and other tissues in bound form ... or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various ... or memory enhancement, most available research suggest exercising caution in their recommendation as much …
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids ... Imino Acids …
L-tartaric acid
Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.
Experimental
Matched Synonyms: … (+)-Tartaric acid ... (+)-L-tartaric acid ... (+)-(R,R)-tartaric acid …
Matched Name: … L-tartaric acid …
Matched Iupac: … (2R,3R)-2,3-dihydroxybutanedioic acid …
Matched Description: … in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics ... , and is a dihydroxyl derivative of succinic acid. ... Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Carboxylic Acids ... Hydroxy Acids ... Dicarboxylic Acids …
Matched Name: … L-tartaric acid …
Matched Iupac: … (2R,3R)-2,3-dihydroxybutanedioic acid …
Matched Description: … in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics ... , and is a dihydroxyl derivative of succinic acid. ... Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Carboxylic Acids ... Hydroxy Acids ... Dicarboxylic Acids …
OSI-027
OSI-027 has been used in trials studying the treatment of Any Solid Tumor or Lymphoma.
Investigational
Matched Synonyms: … CYCLOHEXANECARBOXYLIC ACID, 4-(4-AMINO-5-(7-METHOXY-1H-INDOL-2-YL)IMIDAZO(5,1-F)(1,2,4)TRIAZIN-7-YL)- …
Matched Iupac: … acid ... (1r,4r)-4-[4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[4,3-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic …
Matched Iupac: … acid ... (1r,4r)-4-[4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[4,3-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic …
Norvaline
Norvaline is an isomer of the more common amino acid valine.
Experimental
Matched Synonyms: … 2-Aminovaleric acid ... 2-Aminopentanoic acid ... (S)-2-Aminopentanoic acid …
Matched Iupac: … (2S)-2-aminopentanoic acid …
Matched Description: … Norvaline is an isomer of the more common amino acid valine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Branched-Chain …
Matched Iupac: … (2S)-2-aminopentanoic acid …
Matched Description: … Norvaline is an isomer of the more common amino acid valine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Branched-Chain …
Oxaloacetic acid
Investigational
Matched Synonyms: … Oxalacetic acid ... 2-oxobutanedioic acid ... Ketosuccinic acid …
Matched Name: … Oxaloacetic acid …
Matched Iupac: … 2-oxobutanedioic acid …
Matched Categories: … Acids, Acyclic ... Keto Acids ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … Oxaloacetic acid …
Matched Iupac: … 2-oxobutanedioic acid …
Matched Categories: … Acids, Acyclic ... Keto Acids ... Carboxylic Acids ... Dicarboxylic Acids …
alpha-Linolenic acid
Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Approved
Investigational
Nutraceutical
Matched Synonyms: … (9,12,15)-linolenic acid ... Linolenic acid ... α-linolenic acid …
Matched Name: … alpha-Linolenic acid …
Matched Iupac: … (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid …
Matched Description: … It is a component of many common vegetable oils and is important to human nutrition. ... Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. …
Matched Categories: … Fatty Acids ... Linolenic Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Matched Name: … alpha-Linolenic acid …
Matched Iupac: … (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid …
Matched Description: … It is a component of many common vegetable oils and is important to human nutrition. ... Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. …
Matched Categories: … Fatty Acids ... Linolenic Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Iodamide
Iodamide is a contrast medium molecule that is no longer marketed in the United States.
Withdrawn
Matched Synonyms: … Ametriiodic acid ... Ametriiodinic acid ... Ametriodinic acid …
Matched Iupac: … 3-acetamido-5-(acetamidomethyl)-2,4,6-triiodobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Triiodobenzoic Acids …
Matched Iupac: … 3-acetamido-5-(acetamidomethyl)-2,4,6-triiodobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Triiodobenzoic Acids …
Domoic Acid
Experimental
Matched Synonyms: … L-domoic acid ... (-)-domoic acid …
Matched Name: … Domoic Acid …
Matched Iupac: … 3S,4S)-4-[(2Z,4E,6R)-6-carboxy-6-methylhexa-2,4-dien-2-yl]-3-(carboxymethyl)pyrrolidine-2-carboxylic acid …
Matched Name: … Domoic Acid …
Matched Iupac: … 3S,4S)-4-[(2Z,4E,6R)-6-carboxy-6-methylhexa-2,4-dien-2-yl]-3-(carboxymethyl)pyrrolidine-2-carboxylic acid …
Thiosulfuric acid
Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Synonyms: … Sulfurothioic S-acid ... Monosulfanemonosulfonic acid …
Matched Name: … Thiosulfuric acid …
Matched Description: … Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate ... Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has ... a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid …
Matched Categories: … Acids ... Sulfur Acids ... Sulfuric Acids …
Matched Name: … Thiosulfuric acid …
Matched Description: … Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate ... Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has ... a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid …
Matched Categories: … Acids ... Sulfur Acids ... Sulfuric Acids …
p-Nitrophenylacetic acid
Experimental
Matched Synonyms: … (4-nitrophenyl)acetic acid ... 4-nitrobenzeneacetic acid ... 4-nitrophenylacetic acid …
Matched Name: … p-Nitrophenylacetic acid …
Matched Iupac: … 2-(4-nitrophenyl)acetic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … p-Nitrophenylacetic acid …
Matched Iupac: … 2-(4-nitrophenyl)acetic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
D-Malic acid
Experimental
Matched Synonyms: … (+)-D-malic acid ... (R)-malic acid ... (R)-2-hydroxybutanedioic acid …
Matched Name: … D-Malic acid …
Matched Iupac: … (2R)-2-hydroxybutanedioic acid …
Matched Name: … D-Malic acid …
Matched Iupac: … (2R)-2-hydroxybutanedioic acid …
Alrizomadlin
Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. It is being investigated in cancers.[A257281,A257286]
Investigational
Matched Synonyms: … ]-5'-carboxamido)bicyclo [2.2.2]octane-1-carboxylic acid ... -1'-ethyl-spiro(cyclohexane-1,2'-pyrrolidine)-5'-carbonyl)-amino)-bicyclo(2.2.2)octane-1-carboxylic acid ... Bicyclo(2.2.2)octane-1-carboxylic acid, 4-((((3'r,4's,5'r)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1' …
Matched Iupac: … ]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic acid ... -chloro-2-fluorophenyl)-1'-ethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indol …
Matched Description: … Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. …
Matched Iupac: … ]-5'-yl]amido}bicyclo[2.2.2]octane-1-carboxylic acid ... -chloro-2-fluorophenyl)-1'-ethyl-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indol …
Matched Description: … Alrizomadlin is a novel MDM2 inhibitor that blocks the interaction of MDM2 and p53. …
Displaying drugs 726 - 750 of 2795 in total