Displaying drugs 726 - 750 of 4257 in total
N-[(6-butoxynaphthalen-2-yl)sulfonyl]-D-glutamic acid
Experimental
Matched Name: … N-[(6-butoxynaphthalen-2-yl)sulfonyl]-D-glutamic acid …
Matched Iupac: … (2R)-2-(6-butoxynaphthalene-2-sulfonamido)pentanedioic acid …
Matched Iupac: … (2R)-2-(6-butoxynaphthalene-2-sulfonamido)pentanedioic acid …
Aceglutamide
Experimental
Matched Synonyms: … N-acetyl-L-glutamine …
Matched Iupac: … (2S)-4-carbamoyl-2-acetamidobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino ... Amino Acids, Neutral …
Matched Iupac: … (2S)-4-carbamoyl-2-acetamidobutanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Basic ... Amino Acids, Diamino ... Amino Acids, Neutral …
N,N-Dimethyl-L-Alanine
Experimental
Matched Name: … N,N-Dimethyl-L-Alanine …
Matched Iupac: … (2S)-2-(dimethylamino)propanoic acid …
Matched Iupac: … (2S)-2-(dimethylamino)propanoic acid …
Prednisolone acetate
Prednisolone acetate is a prednisolone molecule bound to an acetate functional group by an ester bond. Prednisolone acetate was granted FDA approval in 1955.
Approved
Vet approved
Matched Synonyms: … Prednisolone acetate …
Matched Name: … Prednisolone acetate …
Matched Iupac: … 11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Description: … Prednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond ... [L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449] …
Matched Products: … PRED NF ... Prednisolone Acetate ... Prednisolone Acetate PF …
Matched Name: … Prednisolone acetate …
Matched Iupac: … 11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Description: … Prednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond ... [L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449] …
Matched Products: … PRED NF ... Prednisolone Acetate ... Prednisolone Acetate PF …
Captopril
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Approved
Matched Synonyms: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid ... D-2-methyl-3-mercaptopropanoyl-L-proline ... D-3-mercapto-2-methylpropanoyl-L-proline …
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Diuretics ... captopril and diuretics ... Amino Acids ... Imino Acids …
Matched Products: … HISTIDIN C CAPTOPRIL ITALMEX ... HISTIDIN C (CAPTOPRIL) TABLETAS 50 MG ... Nu-capto Tab 50mg …
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins ... ACE Inhibitors and Diuretics ... captopril and diuretics ... Amino Acids ... Imino Acids …
Matched Products: … HISTIDIN C CAPTOPRIL ITALMEX ... HISTIDIN C (CAPTOPRIL) TABLETAS 50 MG ... Nu-capto Tab 50mg …
Reltecimod
Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections).
Investigational
Matched Synonyms: … D-alanyl-L-seryl-L-prolyl-L-methionyl-L-leucyl-L-valyl-L-alanyl-L-tyrosyl-L-aspartyl-D-alanine …
Matched Iupac: … methylbutanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-{[(1R)-1-carboxyethyl]carbamoyl}propanoic acid …
Matched Description: … Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Costimulatory and Inhibitory T-Cell Receptors …
Matched Iupac: … methylbutanamido]propanamido]-3-(4-hydroxyphenyl)propanamido]-3-{[(1R)-1-carboxyethyl]carbamoyl}propanoic acid …
Matched Description: … Reltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Costimulatory and Inhibitory T-Cell Receptors …
Fludrocortisone
Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Matched International brands: … Florinef Acetaat …
Matched Description: … A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and …
Matched Salts name: … Fludrocortisone acetate …
Matched Categories: … Sex Hormones and Insulins ... fludrocortisone and antiinfectives ... fludrocortisone and antiinfectives ... Hormones, Hormone Substitutes, and Hormone Antagonists ... fludrocortisone and antiinfectives …
Matched Products: … Florinef Acetate ... Fludrocortisone Acetate ... Florinef Acetate 0.1mg …
Matched Description: … A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and …
Matched Salts name: … Fludrocortisone acetate …
Matched Categories: … Sex Hormones and Insulins ... fludrocortisone and antiinfectives ... fludrocortisone and antiinfectives ... Hormones, Hormone Substitutes, and Hormone Antagonists ... fludrocortisone and antiinfectives …
Matched Products: … Florinef Acetate ... Fludrocortisone Acetate ... Florinef Acetate 0.1mg …
Methionine Phosphonate
Experimental
Matched Name: … Methionine Phosphonate …
Matched Iupac: … [(1R)-1-amino-3-(methylsulfanyl)propyl]phosphonic acid …
Matched Iupac: … [(1R)-1-amino-3-(methylsulfanyl)propyl]phosphonic acid …
D-Threonine
Experimental
Matched Name: … D-Threonine …
Matched Iupac: … (2R,3R)-2-amino-3-hydroxybutanoic acid …
Matched Iupac: … (2R,3R)-2-amino-3-hydroxybutanoic acid …
Teropavimab
Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection).
Investigational
Matched Synonyms: … Immunoglobulin g1 (434-leucine,440-serine), anti-(human immunodeficiency virus 1 envelope protein gp120env …
Matched Description: … Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …
Matched Description: … Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …
Pantothenyl-Aminoethanol-Acetate Pivalic Acid
Experimental
Matched Name: … Pantothenyl-Aminoethanol-Acetate Pivalic Acid …
Acetylcysteine
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168]
Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Synonyms: … NAC ... Mercapturic acid ... (R)-mercapturic acid …
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid …
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... L-Methyl MC NAC …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Matched Products: … Acetadote ... N-ACE ... N - ACE …
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid …
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... L-Methyl MC NAC …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Matched Products: … Acetadote ... N-ACE ... N - ACE …
Furosemide
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Synonyms: … 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid ... 4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid ... 4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid …
Matched Iupac: … 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid …
Matched Description: … It is an anthranilic acid derivative. ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in ... both pediatric and adult patients. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... High-Ceiling Diuretics and Potassium-Sparing Agents ... furosemide and potassium ... furosemide and potassium-sparing agents …
Matched Products: … Ntp-furosemide ... Nu-furosemide Tablets …
Matched Iupac: … 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid …
Matched Description: … It is an anthranilic acid derivative. ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in ... both pediatric and adult patients. …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... High-Ceiling Diuretics and Potassium-Sparing Agents ... furosemide and potassium ... furosemide and potassium-sparing agents …
Matched Products: … Ntp-furosemide ... Nu-furosemide Tablets …
MALP-2
Investigational
Matched Synonyms: … -aspartyl-l-.alpha. ... -glutamyl-l-seryl-l-asparaginyl-l-isoleucyl-l-seryl-l-phenylalanyl-l-lysyl-l-.alpha.-glutamyl- ... L-lysine, s-((2r)-2,3-bis((1-oxohexadecyl)oxy)propyl)-l-cysteinylglycyl-l-asparaginyl-l-asparaginyl-l …
Matched Iupac: … methylpentanamido]-3-hydroxypropanamido]-3-phenylpropanamido]hexanamido]-4-carboxybutanamido]hexanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … methylpentanamido]-3-hydroxypropanamido]-3-phenylpropanamido]hexanamido]-4-carboxybutanamido]hexanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Clavulanic acid
Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with Amoxicillin or Ticarcillin to fight antibiotic resistance by preventing their degradation by beta-lactamase enzymes, broadening their spectrum of susceptible bacterial infections. Clavulanic acid is derived from the organism Streptomyces clavuligerus. When it is combined with amoxicillin, clavulanic acid is...
Approved
Vet approved
Matched Synonyms: … Clavulanic acid ... Acide clavulanique ... Acidum clavulanicum …
Matched Name: … Clavulanic acid …
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … [T665] Clavulanic acid is derived from the organism Streptomyces clavuligerus. ... Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin ... [A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav …
Matched Mixtures name: … ACIX® ... AMOXICILLINA E ACIDO CLAVULANICO KABI ... AMOXICILLINA E ACIDO CLAVULANICO KABI …
Matched Name: … Clavulanic acid …
Matched Iupac: … (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … [T665] Clavulanic acid is derived from the organism Streptomyces clavuligerus. ... Clavulanic acid is a beta-lactamase inhibitor that is frequently combined with [Amoxicillin] or [Ticarcillin ... [A182228]When it is combined with amoxicillin, clavulanic acid is frequently known as Augmentin, Co-Amoxiclav …
Matched Mixtures name: … ACIX® ... AMOXICILLINA E ACIDO CLAVULANICO KABI ... AMOXICILLINA E ACIDO CLAVULANICO KABI …
Aceclofenac
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Synonyms: … glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate ester ... 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetic acid ... 2-[(2',6'-dichlorophenyl)amino]phenylacetoxyacetic acid …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid …
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Antiinflammatory and Antirheumatic Products ... Acids, Carbocyclic ... Topical Products for Joint and Muscular Pain …
Matched Iupac: … 2-[(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)oxy]acetic acid …
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Antiinflammatory and Antirheumatic Products ... Acids, Carbocyclic ... Topical Products for Joint and Muscular Pain …
Desoxycorticosterone acetate
Approved
Matched Synonyms: … Desoxycortone acetate ... Deoxycorticosterone acetate ... 11-deoxycorticosterone acetate …
Matched Name: … Desoxycorticosterone acetate …
Matched Iupac: … -oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Desoxycorticosterone acetate …
Matched Iupac: … -oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Frexalimab
Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis).
Investigational
Matched Synonyms: … Immunoglobulin G1 (272-arginine,325-alanine), anti-(human CD40 ligand) (human-mus musculus monoclonal …
Matched Description: … Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab …
Matched Description: … Frexalimab is under investigation in clinical trial NCT06141486 (Efficacy and Safety Study of Frexalimab …
Phenprocoumon
Coumarin derivative that acts as a long-acting oral anticoagulant.
Approved
Investigational
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … PHENPROCOUMON ACIS 3MG TAB …
Matched Products: … PHENPROCOUMON ACIS 3MG TAB …
Etidronic acid
Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Synonyms: … Etidronic acid ... acide étidronique ... acidum etidronicum …
Matched Name: … Etidronic acid …
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid …
Matched Description: … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and …
Matched Mixtures name: … Ntp-etidronate Calcium …
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... etidronic acid …
Matched Name: … Etidronic acid …
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid …
Matched Description: … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and …
Matched Mixtures name: … Ntp-etidronate Calcium …
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization ... etidronic acid …
Abiraterone
Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Description: … hydrolysis by esterases, abiraterone acetate was developed as an orally bioavailable prodrug with enhanced ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... ] and September 2011,[A260880] respectively. …
Matched Salts name: … Abiraterone acetate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Nat-abiraterone ... Abiraterone Acetate ... Abiraterone acetate …
Matched Salts name: … Abiraterone acetate …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … Nat-abiraterone ... Abiraterone Acetate ... Abiraterone acetate …
Levocetirizine
Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of cetirizine. Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. Levocetirizine was granted FDA approval in 1995.
Approved
Matched Synonyms: … 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Iupac: … 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Description: … Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic ... [L7694] Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. …
Matched Mixtures name: … NORAVER® NF DIA ... LEVOC® NF JARABE ... LEVOC ® NF CAPSULAS …
Matched Categories: … Cetirizine and isomer ... Histamine H1 Antagonists, Non-Sedating ... Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Zyr-NEX TABLET 5 mg ... HISTRINE LEVO ... HISTADINE 5MG TABLETAS RECUBIERTAS …
Matched Iupac: … 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Description: … Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic ... [L7694] Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. …
Matched Mixtures name: … NORAVER® NF DIA ... LEVOC® NF JARABE ... LEVOC ® NF CAPSULAS …
Matched Categories: … Cetirizine and isomer ... Histamine H1 Antagonists, Non-Sedating ... Histamine Agents ... Histamine Antagonists ... Histamine H1 Antagonists …
Matched Products: … Zyr-NEX TABLET 5 mg ... HISTRINE LEVO ... HISTADINE 5MG TABLETAS RECUBIERTAS …
Daprodustat
Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK.[A254167,A254162] Patients with CKD cannot induce erythropoietin (EPO) production in response to hypoxia or anemia. As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular HIF1α and HIF2α and the induces...
Approved
Investigational
Matched Synonyms: … Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)- …
Matched Iupac: … 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic acid …
Matched Description: … HIF1α and HIF2α and the induces erythropoiesis. ... As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular ... to erythropoiesis-stimulating agents regarding the change in the hemoglobin level from baseline and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors …
Matched Iupac: … 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic acid …
Matched Description: … HIF1α and HIF2α and the induces erythropoiesis. ... As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular ... to erythropoiesis-stimulating agents regarding the change in the hemoglobin level from baseline and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors …
Disomotide
Disomotide is a synthetic peptide cancer vaccine.
Investigational
Matched Synonyms: … L-valine, l-isoleucyl-l-methionyl-l-.alpha. ... -aspartyl-l-glutaminyl-l-valyl-l-prolyl-l-phenylalanyl-l-seryl- …
ACV tripeptide
Experimental
Matched Synonyms: … N-[L-5-Amino-5-carboxypentanoyl]-L-cysteinyl-D-valine ... delta(L-2-Aminoadipyl)-L-cysteinyl-D-valine ... L-delta-(alpha-Aminoadipoyl)-L-cysteinyl-D-valine …
Matched Iupac: … )-2-amino-5-{[(1R)-1-{[(1R)-1-carboxy-2-methylpropyl]carbamoyl}-2-sulfanylethyl]carbamoyl}pentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Iupac: … )-2-amino-5-{[(1R)-1-{[(1R)-1-carboxy-2-methylpropyl]carbamoyl}-2-sulfanylethyl]carbamoyl}pentanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 726 - 750 of 4257 in total