Displaying drugs 751 - 775 of 2337 in total
Lofexidine
Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of opioid withdrawal in the United Kingdom in 1992. It was first studied for use as an antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment...
Approved
Investigational
Matched Synonyms: … 2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline …
Matched Description: … [T209] Lofexidine was developed by US Woldmeds LLC and it was approved by the FDA on May 16, 2018. ... Lofexidine was then repurposed for the treatment of opioid withdrawal, as it was seen to be more economical and ... Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved …
Matched Categories: … Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Description: … [T209] Lofexidine was developed by US Woldmeds LLC and it was approved by the FDA on May 16, 2018. ... Lofexidine was then repurposed for the treatment of opioid withdrawal, as it was seen to be more economical and ... Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved …
Matched Categories: … Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Alpha-D-Glucose 1,6-Bisphosphate
Experimental
Matched Name: … Alpha-D-Glucose 1,6-Bisphosphate …
Matched Iupac: … {[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[(phosphonooxy)methyl]oxan-2-yl]oxy}phosphonic acid …
Matched Iupac: … {[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[(phosphonooxy)methyl]oxan-2-yl]oxy}phosphonic acid …
Alpha-Benzyl-Aminobenzyl-Phosphonic Acid
Experimental
Matched Name: … Alpha-Benzyl-Aminobenzyl-Phosphonic Acid …
Matched Iupac: … [(R)-(benzylamino)(phenyl)methyl]phosphonic acid …
Matched Iupac: … [(R)-(benzylamino)(phenyl)methyl]phosphonic acid …
2-Deoxy-alpha-D-galactopyranose
Experimental
Matched Synonyms: … 2-Deoxy-alpha-D-lyxo-hexopyranose …
Matched Name: … 2-Deoxy-alpha-D-galactopyranose …
Matched Name: … 2-Deoxy-alpha-D-galactopyranose …
Alpha-N-Dichloroacetyl-P-Aminophenylserinol
Experimental
Matched Name: … Alpha-N-Dichloroacetyl-P-Aminophenylserinol …
alpha-Keto-beta-methylvaleric acid
Experimental
Matched Name: … alpha-Keto-beta-methylvaleric acid …
Matched Iupac: … 3-methyl-2-oxopentanoic acid …
Matched Salts name: … Calcium alpha-Keto-beta-methylvaleric acid …
Matched Iupac: … 3-methyl-2-oxopentanoic acid …
Matched Salts name: … Calcium alpha-Keto-beta-methylvaleric acid …
Interferon alfa-n1
Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.
Approved
Investigational
Matched Synonyms: … Interferon alpha-n1 (INS) …
Matched Description: … from individual alpha interferon genes. ... Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least ... This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … from individual alpha interferon genes. ... Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least ... This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Etryptamine
In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. αET was an FDA approved antidepressant under the name Monase. However, in 1962, after the discovery of an unacceptable incidence of agranulocytosis,...
Illicit
Investigational
Withdrawn
Matched Synonyms: … alpha-ethyltryptamine …
Matched Description: … αET is a stimulant and hallucinogen, but it is less stimulating and hallucinogenic than alpha-methyltryptamine ... the discovery of an unacceptable incidence of agranulocytosis, the development of Monase was halted and ... Like MDMA, increases in locomotor activity and mood elevation can be seen post administration. …
Matched Salts name: … Alpha-ethyltryptamine acetate …
Matched Description: … αET is a stimulant and hallucinogen, but it is less stimulating and hallucinogenic than alpha-methyltryptamine ... the discovery of an unacceptable incidence of agranulocytosis, the development of Monase was halted and ... Like MDMA, increases in locomotor activity and mood elevation can be seen post administration. …
Matched Salts name: … Alpha-ethyltryptamine acetate …
N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine
Experimental
Matched Synonyms: … Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanyl-D-alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
6-o-Capryloylsucrose
Experimental
Matched Synonyms: … alpha-D-Glucopyranoside, 6-O-(1-oxooctyl)-beta-D-fructofuranosyl …
Matched Iupac: … -5-(hydroxymethyl)-5-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxolan-2-yl]methyl …
Matched Iupac: … -5-(hydroxymethyl)-5-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxolan-2-yl]methyl …
Chymotrypsin
Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. Like most proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence...
Approved
Vet approved
Matched Synonyms: … alpha-Chymotrypsin …
Matched Description: … Chymotrypsin contains both the catalytic triad and oxyanion hole, and the tertiary structure of chymotrypsin ... Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and ... It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Description: … Chymotrypsin contains both the catalytic triad and oxyanion hole, and the tertiary structure of chymotrypsin ... Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and ... It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. …
Matched Categories: … Blood and Blood Forming Organs ... Enzymes and Coenzymes …
PIK3CA
PIK3CA is under investigation in clinical trial NCT02957266 (Cervical Cancer Radiotherapy by Use of VMAT, Individualized Polyradiosensitization and Interstitial Brachytherapy).
Investigational
Matched Synonyms: … Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform …
Matched Description: … trial NCT02957266 (Cervical Cancer Radiotherapy by Use of VMAT, Individualized Polyradiosensitization and …
Matched Description: … trial NCT02957266 (Cervical Cancer Radiotherapy by Use of VMAT, Individualized Polyradiosensitization and …
LSTA1
Investigational
Matched Synonyms: … L-cysteine, l-cysteinyl-l-arginylglycyl-l-.alpha.-aspartyl-l-lysylglycyl-l-prolyl-l-.alpha. …
Idursulfase
Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Synonyms: … Alpha-L-iduronate sulfate sulfatase …
Matched Description: … -sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … -sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Cefuroxime
Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
Approved
Matched Synonyms: … (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo …
Matched Iupac: … (6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo …
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Matched Iupac: … (6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo …
Matched Description: … It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus …
Matched Categories: … cefuroxime and metronidazole …
Matched Products: … Cefuroxime and Dextrose …
Brimonidine
Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Description: … Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in ... Early treatment and management of glaucoma, which predominantly involves the lowering of intraocular ... Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and …
Matched Mixtures name: … Brimonidine Tartrate and Timolol Maleate ... BRIMONIDINE TARTRATE and TIMOLOL MALEATE ... Brimonidine Tartrate and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Decongestants and Antiallergics ... Skin and Mucous Membrane Agents ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Alpha-Vision sine 2 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis …
Matched Mixtures name: … Brimonidine Tartrate and Timolol Maleate ... BRIMONIDINE TARTRATE and TIMOLOL MALEATE ... Brimonidine Tartrate and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Decongestants and Antiallergics ... Skin and Mucous Membrane Agents ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Alpha-Vision sine 2 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis …
Methylparaben
Methylparaben is used in allergenic testing.
Approved
Matched Synonyms: … Methyl paraben ... Methyl 4-hydroxybenzoate ... methyl p-hydroxybenzoate …
Matched Iupac: … methyl 4-hydroxybenzoate …
Matched Iupac: … methyl 4-hydroxybenzoate …
Thymalfasin
Thymalfasin is a chemically synthesized version of thymosin alpha 1 that is identical to human thymosin alpha 1. Thymosin alpha 1 is an acetylated polypeptide. Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. It is also used to boost the...
Investigational
Matched Synonyms: … Thymosin alpha1 (human) …
Matched Description: … Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. ... alpha 1. ... Thymosin alpha 1 is an acetylated polypeptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Thymosin alpha 1 is now approved in 35 developing countries for the treatment of Hepatitis B and C. ... alpha 1. ... Thymosin alpha 1 is an acetylated polypeptide. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
methyl beta-D-glucopyranoside
Experimental
Matched Synonyms: … O1-methyl-glucose ... beta-methyl-D-glucoside ... Methyl hexopyranoside …
Matched Name: … methyl beta-D-glucopyranoside …
Matched Name: … methyl beta-D-glucopyranoside …
5-(2-hydroxyethyl)-4-methylthiazole
Experimental
Matched Synonyms: … 4-Methyl-5-thiazolethanol ... 4-Methyl-5-thiazoleethanol ... 4-Methyl-5-hydroxethylthiazole …
Matched Iupac: … 2-(4-methyl-1,3-thiazol-5-yl)ethan-1-ol …
Matched Iupac: … 2-(4-methyl-1,3-thiazol-5-yl)ethan-1-ol …
Travoprost
Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist. It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher...
Approved
Matched Synonyms: … (1R-(1.ALPHA. ... ISOPROPYL (Z)-7-((1R,2R,3R,5S)-3,5-DIHYDROXY-2-((1E,3R)-3-HYDROXY-4-((.ALPHA.,.ALPHA.,.ALPHA. ... (Z),2.BETA.(1E,3R*),3.ALPHA.,5.ALPHA.))-7-(3,5-DIHYDROXY-2-(3-HYDROXY-4-(3-(TRIFLUOROMETHYL)PHENOXY)- …
Matched Description: … Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective ... It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. ... [L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Description: … Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective ... It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. ... [L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity …
Matched Categories: … Antiglaucoma Preparations and Miotics …
N-omega-nitro-L-arginine methyl ester
L-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury.
Investigational
Matched Synonyms: … N-nitro-arginine methyl ester ... NG-Nitroarginine methyl ester ... NG-nitro-L-arginine methyl ester …
Matched Name: … N-omega-nitro-L-arginine methyl ester …
Matched Iupac: … methyl (2S)-2-amino-5-(N'-nitrocarbamimidamido)pentanoate …
Matched Description: … L-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … N-omega-nitro-L-arginine methyl ester …
Matched Iupac: … methyl (2S)-2-amino-5-(N'-nitrocarbamimidamido)pentanoate …
Matched Description: … L-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Velmanase alfa
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Recombinant Human Alpha Mannosidase …
Matched Description: … sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... to treat alpha-mannosidosis. …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Recombinant Human Lysosomal alpha-Mannosidase …
Matched Description: … sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... to treat alpha-mannosidosis. …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Recombinant Human Lysosomal alpha-Mannosidase …
Displaying drugs 751 - 775 of 2337 in total