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Displaying drugs 751 - 775 of 2570 in total
Obeticholic acid
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … Obeticholic acid ... 6-ethylchenodeoxycholic acid ... 6α-ethylchenodeoxycholic acid …
Matched Name: … Obeticholic acid …
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Cholic Acids …
Matched Name: … Obeticholic acid …
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Cholic Acids …
NKX101
NKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy.
Investigational
Matched Synonyms: … NK) cell therapy engineered with an NKG2D ACR, OX40 costimulatory domain, CD3zeta signaling moiety, and …
AD-214
Investigational
Matched Synonyms: … Fc-fusion protein comprised of an anti-CXCR4 i-body tethered at its C-terminus to constant domains 2 and …
4-(Dimethylamino)benzoic acid
Experimental
Matched Synonyms: … p-Dimethylamino benzoic acid ... N,N-Dimethyl-4-aminobenzoic acid ... N,N-Dimethyl-p-aminobenzoic acid …
Matched Name: … 4-(Dimethylamino)benzoic acid …
Matched Iupac: … 4-(dimethylamino)benzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Name: … 4-(Dimethylamino)benzoic acid …
Matched Iupac: … 4-(dimethylamino)benzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Ketoprofen
Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Approved
Vet approved
Matched Synonyms: … 3-Benzoylhydratropic acid ... m-Benzoylhydratropic acid ... 2-(3-Benzoylphenyl)propionic acid …
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid …
Matched Description: … and antipyretic properties. ... Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Ketoprofen and isomer ... Amino Acids ... Acids, Carbocyclic ... Amino Acids, Basic …
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid …
Matched Description: … and antipyretic properties. ... Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Ketoprofen and isomer ... Amino Acids ... Acids, Carbocyclic ... Amino Acids, Basic …
Doconexent
A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. It is an omega-3 fatty acid and...
Approved
Investigational
Matched Synonyms: … cervonic acid ... Docosahexanoic Acid ... Docosahexaenoic acid …
Matched Iupac: … (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid …
Matched Description: … A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement ... It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin ... , and retina thus plays an important role in their development and function. …
Matched Mixtures name: … Iron Polysaccharides Folic Acid DHA …
Matched Categories: … Fatty Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Unsaturated …
Matched Iupac: … (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid …
Matched Description: … A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement ... It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin ... , and retina thus plays an important role in their development and function. …
Matched Mixtures name: … Iron Polysaccharides Folic Acid DHA …
Matched Categories: … Fatty Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Unsaturated …
Idroxioleic acid
Investigational
Matched Synonyms: … 2-hydroxyoleic acid ... Alpha-hydroxyoleic acid ... (z)-2-hydroxyoctadec-9-enoic acid …
Matched Name: … Idroxioleic acid …
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Matched Name: … Idroxioleic acid …
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Minoxidil
A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Description: … potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Products: … Up and Up Minoxidil ... Up and Up minoxidil ... Berkley and Jensen Minoxidil …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Products: … Up and Up Minoxidil ... Up and Up minoxidil ... Berkley and Jensen Minoxidil …
N,N-dimethylglycine
Experimental
Matched Synonyms: … (dimethylamino)acetic acid ... 2-(Dimethylamino)acetic acid ... N,N-Dimethylaminoacetic acid …
Matched Iupac: … 2-(dimethylamino)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … 2-(dimethylamino)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Nitrilotriacetic acid
Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.)
Experimental
Matched Synonyms: … Triglycollamic acid ... nitrilo-2,2',2''-triacetic acid ... α,α',α''-trimethylaminetricarboxylic acid …
Matched Name: … Nitrilotriacetic acid …
Matched Iupac: … 2-[bis(carboxymethyl)amino]acetic acid …
Matched Description: … Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acetates ... Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Nitrilotriacetic acid …
Matched Iupac: … 2-[bis(carboxymethyl)amino]acetic acid …
Matched Description: … Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acetates ... Acids, Acyclic ... Carboxylic Acids …
Aminohippuric acid
The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Synonyms: … Aminohippuric acid ... 4-aminohippuric acid ... p-aminohippuric acid …
Matched Name: … Aminohippuric acid …
Matched Iupac: … 2-[(4-aminophenyl)formamido]acetic acid …
Matched Description: … The glycine amide of 4-aminobenzoic acid. ... Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory …
Matched Categories: … Indicators and Reagents ... Benzamides and benzamide derivatives ... Tests for Renal Function and Ureteral Injuries ... Keto Acids ... Acids, Carbocyclic …
Matched Name: … Aminohippuric acid …
Matched Iupac: … 2-[(4-aminophenyl)formamido]acetic acid …
Matched Description: … The glycine amide of 4-aminobenzoic acid. ... Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory …
Matched Categories: … Indicators and Reagents ... Benzamides and benzamide derivatives ... Tests for Renal Function and Ureteral Injuries ... Keto Acids ... Acids, Carbocyclic …
Ibuprofen
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. Ibuprofen was finally patented in 1961 and...
Approved
Matched Synonyms: … 4-isobutylhydratropic acid ... (±)-p-isobutylhydratropic acid ... (±)-2-(p-isobutylphenyl)propionic acid …
Matched Iupac: … 2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered ... [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development ... in the UK in 1969 and USA in 1974. …
Matched Mixtures name: … Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% ... Up and Up Cold and Sinus ... Advil Cold and Sinus …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Arylpropionic acid NSAIDS ... Ibuprofen and isomer ... codeine and ibuprofen …
Matched Products: … Pain and Fever ... Up and Up Ibuprofen ... Advil Muscle and Joint …
Matched Iupac: … 2-[4-(2-methylpropyl)phenyl]propanoic acid …
Matched Description: … Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered ... [A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development ... in the UK in 1969 and USA in 1974. …
Matched Mixtures name: … Cimetidine 5% / Ibuprofen 2% / Salicylic Acid 17% ... Up and Up Cold and Sinus ... Advil Cold and Sinus …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Arylpropionic acid NSAIDS ... Ibuprofen and isomer ... codeine and ibuprofen …
Matched Products: … Pain and Fever ... Up and Up Ibuprofen ... Advil Muscle and Joint …
1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE
Experimental
Matched Name: … 1,1,1-TRIFLUORO-3-(OCTYLTHIO)ACETONE …
3-hydroxyanthranilic acid
An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
Experimental
Matched Synonyms: … 3-Oxyanthranilic acid ... 2-Amino-3-hydroxy-benzoic acid ... 2-Amino-3-Hydroxybenzoic Acid …
Matched Name: … 3-hydroxyanthranilic acid …
Matched Iupac: … 2-amino-3-hydroxybenzoic acid …
Matched Description: … It may be a free radical scavenger and a carcinogen. …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Name: … 3-hydroxyanthranilic acid …
Matched Iupac: … 2-amino-3-hydroxybenzoic acid …
Matched Description: … It may be a free radical scavenger and a carcinogen. …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Diphenhydramine
Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Description: … stings, and rashes [L5263, L5266, L5269, F3379]. ... However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. ... receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and …
Matched Mixtures name: … Diphenhydramine HCl and Zinc Acetate ... Diphenhydramine HCl and Zinc Acetate ... Diphenhydramine HCl and Zinc Acetate …
Matched Categories: … Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy ... Up and Up Nighttime Sleep-aid …
Matched Mixtures name: … Diphenhydramine HCl and Zinc Acetate ... Diphenhydramine HCl and Zinc Acetate ... Diphenhydramine HCl and Zinc Acetate …
Matched Categories: … Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy ... Up and Up Nighttime Sleep-aid …
NGN-401
NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 (MECP2). Developed by Neurogene Inc., it is being investigated for the treatment of Rett syndrome.
Investigational
Matched Synonyms: … virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and …
Matched Description: … virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and …
Matched Description: … virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and …
AOC-1020
AOC-1020 is an antibody oligonucleotide conjugate, comprised of a human transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and a double-stranded siRNA oligonucleotide targeting DUX4.
Investigational
Matched Synonyms: … transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and …
Matched Description: … transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and …
Matched Description: … transferrin receptor 1 targeting, effector function null, humanized IgG1 antibody, a MCC maleimide linker, and …
1-Naphthylamine-5-sulfonic acid
Experimental
Matched Synonyms: … Laurent acid ... 1-Amino-5-naphthalenesufonic acid ... 5-Naphthylamine-1-sulfonic acid …
Matched Name: … 1-Naphthylamine-5-sulfonic acid …
Matched Iupac: … 5-aminonaphthalene-1-sulfonic acid …
Matched Categories: … Sulfur Acids ... Arylsulfonic Acids ... Sulfonic Acids …
Matched Name: … 1-Naphthylamine-5-sulfonic acid …
Matched Iupac: … 5-aminonaphthalene-1-sulfonic acid …
Matched Categories: … Sulfur Acids ... Arylsulfonic Acids ... Sulfonic Acids …
Loratadine
Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.
Approved
Investigational
Matched Description: … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation …
Matched Mixtures name: … Up and Up allergy and congestion relief ... Loratadine and Pseudoephedrine ... Smart Sense allergy and congestion relief indoor and outdoor allergies …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Childrens Allergy Relief …
Matched Mixtures name: … Up and Up allergy and congestion relief ... Loratadine and Pseudoephedrine ... Smart Sense allergy and congestion relief indoor and outdoor allergies …
Matched Categories: … Loratadine and derivatives …
Matched Products: … Up and Up Allergy Relief ... Berkley and Jensen Allergy Relief ... Up and Up Childrens Allergy Relief …
Aminobenzoic acid
A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Approved
Experimental
Matched Synonyms: … Aminobenzoic acid ... 4-aminobenzoic acid ... p-Aminobenzoic acid …
Matched Name: … Aminobenzoic acid …
Matched Iupac: … 4-aminobenzoic acid …
Matched Categories: … Emollients and Protectives ... 4-Aminobenzoic Acid ... Acids, Carbocyclic ... Carboxylic Acids ... aminobenzoic acid …
Matched Name: … Aminobenzoic acid …
Matched Iupac: … 4-aminobenzoic acid …
Matched Categories: … Emollients and Protectives ... 4-Aminobenzoic Acid ... Acids, Carbocyclic ... Carboxylic Acids ... aminobenzoic acid …
N-acetyl-beta-neuraminic acid
An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518)
Experimental
Matched Synonyms: … beta-sialic acid ... N-acetyl-β-neuraminic acid ... (-)-N-acetyl-beta-neuraminic acid …
Matched Name: … N-acetyl-beta-neuraminic acid …
Matched Iupac: … (2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
Matched Description: … N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and ... An N-acyl derivative of neuraminic acid. …
Matched Name: … N-acetyl-beta-neuraminic acid …
Matched Iupac: … (2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid …
Matched Description: … N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and ... An N-acyl derivative of neuraminic acid. …
Proline
Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. Proline is sometimes called an imino acid, although the IUPAC definition of an imine requires a carbon-nitrogen double bond. Proline is a non-essential amino acid that is synthesized from glutamic acid. It...
Nutraceutical
Matched Synonyms: … (-)-2-Pyrrolidinecarboxylic acid ... 2-Pyrrolidinecarboxylic acid ... (−)-2-pyrrolidinecarboxylic acid …
Matched Iupac: … (2S)-pyrrolidine-2-carboxylic acid …
Matched Description: … It is an essential component of collagen and is important for proper functioning of joints and tendons ... Proline is a non-essential amino acid that is synthesized from glutamic acid. ... Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic ... Proteinogenic Amino Acids …
Matched Iupac: … (2S)-pyrrolidine-2-carboxylic acid …
Matched Description: … It is an essential component of collagen and is important for proper functioning of joints and tendons ... Proline is a non-essential amino acid that is synthesized from glutamic acid. ... Proline is one of the twenty amino acids used in living organisms as the building blocks of proteins. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Travasol Amino Acid Inj 8.5% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic ... Proteinogenic Amino Acids …
Aminooxyacetic acid
A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem]
Experimental
Matched Synonyms: … aminoxyacetic acid ... (aminooxy)acetic acid …
Matched Name: … Aminooxyacetic acid …
Matched Iupac: … 2-(aminooxy)acetic acid …
Matched Description: … inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid …
Matched Categories: … Acetates ... Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Aminooxyacetic acid …
Matched Iupac: … 2-(aminooxy)acetic acid …
Matched Description: … inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid …
Matched Categories: … Acetates ... Acids, Acyclic ... Carboxylic Acids …
beta-D-Galactopyranuronic acid
Experimental
Matched Synonyms: … β-D-galacturonic acid ... β-D-Galactopyranuronic acid …
Matched Name: … beta-D-Galactopyranuronic acid …
Matched Iupac: … (2S,3R,4S,5R,6R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid …
Matched Name: … beta-D-Galactopyranuronic acid …
Matched Iupac: … (2S,3R,4S,5R,6R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid …
4-hydroxybenzoic acid
Experimental
Matched Synonyms: … p-salicylic acid ... p-Hydroxybenzoic acid …
Matched Name: … 4-hydroxybenzoic acid …
Matched Iupac: … 4-hydroxybenzoic acid …
Matched Categories: … Hydroxy Acids ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Name: … 4-hydroxybenzoic acid …
Matched Iupac: … 4-hydroxybenzoic acid …
Matched Categories: … Hydroxy Acids ... Acids, Carbocyclic ... Carboxylic Acids …
Displaying drugs 751 - 775 of 2570 in total