Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 751 - 775 of 3066 in total
Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders. Pramocaine is available by itself and in combination with other medications...
Approved
Matched Description: … Pramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. ... It is used for many dermatological and anorectal/anogenital conditions including minor cuts/burns, insect ... bites, hives/rashes due to poison ivy exposure, hemorrhoids and other anorectal/anogenital disorders …
Matched Mixtures name: … Gold Bond Anti Itch ... Gold Bond Anti Itch ... Gold Bond Anti-itch Lotion …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antipruritics and Local Anesthetics …
Matched Products: … Gold Bond Intensive Healing Anti Itch Skin Protectant …
Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. It is a rare malignancy, with an estimated yearly incidence of 6.5 people per 100,000, and is variable in its presentation - some patients may remain entirely asymptomatic, while others may experience a range of symptoms including...
Approved
Investigational
Matched Synonyms: … Autologous bi-epitope BCMA-targeted CAR T-cells
Matched Description: … Multiple myeloma is a malignancy involving the plasma cells of the bone marrow. ... plasma cells and most multiple myeloma cell lines, making it a choice target in the development of immunotherapies ... [A245854] While normally expressed on plasma blasts and plasma cells, BCMA is widely expressed on malignant …
Matched Categories: … Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …
Ozekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.
Investigational
Matched Synonyms: … Immunoglobulin, anti-(human death receptor 5) (human-Lama glama clone IF5 single-domain VHH fragment) ... peptide linker (GGS)2 fusion protein with immunoglobulin anti-(human death receptor 5) (human-Lama glama
Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G2-KAPPA, ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN CD3E (T-CELL ... -CHAIN) (HUMAN-MUS MUSCULUS MONOCLONAL PF-06863059 .GAMMA.2-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS ... B-CELL MATURATION ANTIGEN (BCMA) CLUSTER OF DIFFERENTIATION 3 (CD3) BISPECIFIC MONOCLONAL ANTIBODY (MAB …
Matched Description: … immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and ... an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one light chain to drug structure ... Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood Proteins ... Bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager …
Investigational
Matched Synonyms: … Blood group b trisaccharide …
Matched Categories: … ABO Blood-Group System …
Clodronic acid is a first generation bisphosphonate similar to etidronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. clodronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Investigational
Vet approved
Matched Synonyms: … Clodronic acid ... Acido clodronico ... Acide clodronique …
Matched Name: … Clodronic acid
Matched Iupac: … [dichloro(phosphono)methyl]phosphonic acid
Matched Description: … Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid] ... ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... clodronic acid ... Bone Density Conservation Agents ... Drugs for Treatment of Bone Diseases …
Matched Products: … CLODRON 800 1A PHARMA ... ACIDO CLODRONICO SANDOZ ... ACIDO CLODRONICO EG …
Gamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised of 18 carbon atoms with three double bonds that is most commonly found in human milk and other botanical sources . It is an omega-6 polyunsaturated fatty acid (PUFA) also referred to as 18:3n-6;...
Approved
Investigational
Matched Synonyms: … GLA ... gamma-Linolenic acid ... gamoleic acid
Matched Name: … Gamolenic acid
Matched Iupac: … (6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid
Matched Description: … Gamolenic acid, or gamma-linolenic acid (γ-Linolenic acid) or GLA, is an essential fatty acid (EFA) comprised ... of 18 carbon atoms with three double bonds [F27] that is most commonly found in human milk and other ... acid; and cis-6, cis-9, cis-12- octadecatrienoic acid [F27]. …
Matched Mixtures name: … Pro-gla Caps ... Gla 130 Primrose Oil ... Bio-efa Borage Gla 90 Cap …
Matched Categories: … Fatty Acids ... gamolenic acid ... Linolenic Acids ... Fatty Acids, Omega-6 ... Fatty Acids, Essential …
Tisagenlecleucel is a CD19-directed genetically modified autologous T cell immunotherapy, or a CAR-T cell therapy for B-cell acute lymphoblastic leukemia. It was granted approval by FDA in August 2017 under the market name Kymriah. Tisagenlecleucel is an immunocellular therapy that involves autologous T cells that are collected from each individual...
Approved
Investigational
Matched Synonyms: … CAR.CD19-Redirected T cells
Matched Description: … These CD19-directed chimeric antigen receptors (CD19 CAR-T cells) direct the T cells to target and kill ... each individual patient and genetically engineered to express a specific protein called a chimeric antigen ... In a multicenter clinical trial involving pediatric and young adult patients with relapsed or refractory …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents ... Genetically-modified Autologous T Cells
Investigational
Matched Synonyms: … Expanded human allogeneic neural retinal progenitor cells extracted from neural retina …
Matched Name: … Expanded human allogeneic neural retinal progenitor cells extracted from neural retina …
Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral...
Approved
Matched Description: … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and ... with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and ... be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and
Matched Mixtures name: … Clopidogrel/acetylsalicylic Acid Mylan ... Clopidogrel/acetylsalicylic Acid Mylan ... Clopidogrel/acetylsalicylic Acid Mylan …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … CLOPIDOGREL 1A PHARMA ... Clopidogrel 1a Pharma ... Clopido Grel 1a Pharma …
Investigational
Matched Synonyms: … anti-CD5 CAR T cells
Matched Name: … Anti-CD5 CAR T-cell therapy …
Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation. The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ion exchange chromatography. IVIg contains the same distribution of IgG antibody subclasses as is found in the general human population....
Approved
Investigational
Matched Description: … Intravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human ... The purification process includes cold alcohol fractionation, polyethylene glycol precipitation, and ... IgG subclasses are fully represented in the following proportions: 70.3% IgG1, 24.7% IgG2, 3.1% IgG3, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood Proteins …
Matched Products: … LIV-GAMMA SN INJ ... Gammar Inj 165mg/ml ... LİV-GAMMA SN 5 G/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET …
The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and effectiveness against SARS-CoV-2-induced pneumonia. With a better safety profile than inactivated and live-attenuated virus and virus-vector vaccines, the recombinant chimeric DC vaccine reduces the risk of virulence recovery, pre-existing anti-vector immunity, and incomplete viral inactivation. As...
Investigational
Matched Name: … Dendritic cells vaccine …
Matched Description: … With a better safety profile than inactivated and live-attenuated virus and virus-vector vaccines, the ... The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and ... recombinant chimeric DC vaccine reduces the risk of virulence recovery, pre-existing anti-vector immunity, and
A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5.
Investigational
Nutraceutical
Matched International brands: … Star GLA
Matched Synonyms: … gamma-Homolinolenic acid ... Homo-gamma-linolenic acid ... Homo-gamma-linolensäure …
Matched Name: … Dihomo-gamma-linolenic acid
Matched Iupac: … (8Z,11Z,14Z)-icosa-8,11,14-trienoic acid
Matched Description: … A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. ... It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5. …
Matched Salts name: … Sodium dihomo-gamma-linolenate …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated …
A nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur.
Experimental
Matched Synonyms: … (gamma-S)ATP ... ATP-gammaS ... ATP-gamma-S …
Matched Name: … Adenosine 5'-[gamma-thio]triphosphate …
Matched Iupac: … yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonothioic acid
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Indicators and Reagents …
An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports...
Approved
Withdrawn
Matched Synonyms: … gamma-BHC ... gamma-HCH ... gamma-Lindane …
Matched Description: … bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical treatment ... An organochlorine insecticide that has been used as a pediculicide and a scabicide. ... about neurotoxicity and adverse effects on the environment. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides, Insecticides and Repellents …
Matched Products: … Gamma Benzene Hexachloride Lotion USP 1% w/v (LICSCAB Lotion) …
Investigational
Matched Synonyms: … INTERFERON ALPHA 1B ... INTERFERON-ALFA-1B ... Interferon alpha-1b …
Matched Name: … Interferon alfa-1b …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Interferons ... Interferon Type I …
CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD19 antigen …
Matched Description: … CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen …
Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. GM-CSF stimulates proliferation, activation and differentiation of...
Investigational
Matched Synonyms: … GM-CSF (CHO cell) …
Matched Description: … Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and ... Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ ... GM-CSF stimulates proliferation, activation and differentiation of macrophages and granulocytes and their …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hematopoietic Cell Growth Factors ... Intercellular Signaling Peptides and Proteins …
Nerofe is under investigation in clinical trial NCT03059615 (A Phase 2a, Open-Label, Two Stage Study of Nerofe or Nerofe With Doxorubicin in Subjects With AML or MDS).
Investigational
Matched Synonyms: … tumor-cells apoptosis factor ... tumor-cells apoptosis factor hormone-peptide …
Matched Iupac: … methylpentanamido]-3-(1H-indol-3-yl)propanamido]-4-carboxybutanamido]-5-carbamimidamidopentanamido]hexanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins …
Zelpultide alfa is a recombinant human surfactant protein D.
Investigational
Matched Synonyms: … , SURFACTANT PROTEIN D), NON-COVALENT QUADRUPLE TRIMER, PRODUCED IN HUMAN MYELOGENOUS LEUKEMIA K562 CELLS ... PULMONARY SURFACTANT-ASSOCIATED PROTEIN D (HUMAN RECOMBINANT GLYCOEXPRESS MYELOMA CELL HOMOTRIMERIC QUADRAPLEX …
PEGylation is a technology for the chemical attachment of polyethylene glycol (PEG) polymer chains to a broad range of drug substances such as peptides and proteins including antibody fragments; small molecules, and other drugs. [Infergen] is a bio-engineered type I interferon alpha that is FDA-approved for the treatment of patients...
Investigational
Matched Synonyms: … PEG-interferon alfacon-1 ... Pegylated interferon alfacon-1 …
Matched Description: … proteins including antibody fragments; small molecules, and other drugs. ... attachment of polyethylene glycol (PEG) polymer chains to a broad range of drug substances such as peptides and ... [Infergen] is a bio-engineered type I interferon alpha that is FDA-approved for the treatment of patients …
Investigational
Matched Name: … Anti-CD7 CAR T-cell therapy …
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse ... It is also found in plants and is used pharmacologically as a sympathomimetic. …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Alpha-and Beta-adrenergic Agonists ... Epinephrine and similars …
Matched Products: … ADRENOR 4 MG/4 ML IV İNFÜZYONLUK ÇÖZELTİ …
CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.
Investigational
Matched Synonyms: … Allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD70 antigen …
Matched Description: … CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen …
Displaying drugs 751 - 775 of 3066 in total