Displaying drugs 751 - 775 of 1291 in total
Batoprotafib
Batoprotafib is under investigation in clinical trial NCT04330664 (Adagrasib in Combination With TNO155 in Patients With Cancer (KRYSTAL 2)).
Investigational
Matched Synonyms: … SHP2 inhibitor TNO155 ... PTPN11 inhibitor TNO155 …
AD-114
Investigational
Matched Synonyms: … Human single domain antibody-like protein inhibitor of the chemokine receptor type 4 …
NVL-655
NVL-655 is an orally bioavailable, brain-penetrant anaplastic lymphoma kinase (ALK) inhibitor inhibitor being investigated for the treatment of non-small cell lung cancer.
Investigational
Matched Synonyms: … an orally bioavailable ALK inhibitor (a macrocyclic compound containing nitrogen heterocycles) …
Matched Description: … NVL-655 is an orally bioavailable, brain-penetrant anaplastic lymphoma kinase (ALK) inhibitor inhibitor …
Matched Description: … NVL-655 is an orally bioavailable, brain-penetrant anaplastic lymphoma kinase (ALK) inhibitor inhibitor …
Befovacimab
Investigational
Matched Synonyms: … Human tissue factor pathway inhibitor-neutralizing antibody (bay 1093884) ... Immunoglobulin g2, anti-(human tissue factor pathway inhibitor) (human monoclonal 1093884 .gamma.2-chain …
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
Experimental
Matched Synonyms: … histone deacetylase inhibitor III …
RGG0853
RGG0853 is an E1A lipid complex, a repressor gene complexed with a cationic lipid vector.
Investigational
Matched Synonyms: … HER-2/neu inhibitor …
PLX51107
PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family.[A257246,A257251] PLX51107 is under investigation in clinical trial NCT04022785 (PLX51107 and Azacitidine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Brd4 inhibitor plx51107 …
Matched Description: … PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family …
Matched Description: … PLX51107 is a potent and selective inhibitor of the bromodomain and extraterminal (BET) protein family …
N-[2-Hydroxy-2-(8-Isopropyl-6,9-Dioxo-2-Oxa-7,10-Diaza-Bicyclo[11.2.2]Heptadeca-1(16),13(17),14-Trien-11-Yl)-Ethyl]-N-(3-Methyl-Butyl)-Benzenesulfonamide,Inhibitor 3
Experimental
Matched Name: … Diaza-Bicyclo[11.2.2]Heptadeca-1(16),13(17),14-Trien-11-Yl)-Ethyl]-N-(3-Methyl-Butyl)-Benzenesulfonamide,Inhibitor …
Trotabresib
Trotabresib is an oral, potent, and reversible inhibitor of the epigenetic target bromodomain and extra-terminal (BET) proteins.
Investigational
Matched Synonyms: … Bet inhibitor cc-90010 …
Matched Description: … Trotabresib is an oral, potent, and reversible inhibitor of the epigenetic target bromodomain and extra-terminal …
Matched Description: … Trotabresib is an oral, potent, and reversible inhibitor of the epigenetic target bromodomain and extra-terminal …
N-[(benzyloxy)carbonyl]-L-leucyl-N-[(1S)-3-fluoro-1-(4-hydroxybenzyl)-2-oxopropyl]-L-leucinamide
Experimental
Matched Synonyms: … Calpain inhibitor IV …
Muparfostat
Muparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived from the extracellular phosphomannan of the yeast Pichia (Hansenula) holstii, with potential antiangiogenic activity.
Investigational
Matched Synonyms: … Heparanase inhibitor PI-88 …
Cirtuvivint
Cirtuvivint is a first-in-class CDC-like kinase (CLK) inhibitor.
Investigational
Matched Synonyms: … CDC-like kinase inhibitor of the Wnt Pathway …
Matched Description: … Cirtuvivint is a first-in-class CDC-like kinase (CLK) inhibitor. …
Matched Description: … Cirtuvivint is a first-in-class CDC-like kinase (CLK) inhibitor. …
Evexomostat
Evexomostat is under investigation in clinical trial NCT05570253 (A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer).
Investigational
Matched Synonyms: … METAP2 inhibitor SDX-7320 …
Rexin G
Rexin-G is a tumor-targeted, injectable retroviral vector carrying a mutant form of the cyclin G1 gene. It is under development by Epeius Biotechnologies for the potential treatment of metastatic cancer. It is also being investigated for preventing SARSCOV-2 viral entry.
Investigational
Matched Synonyms: … DeltaRex-G Retroviral Vector Encoding a Cyclin G1 Inhibitor …
2-(11-{2-[Benzenesulfonyl-(3-Methyl-Butyl)-Amino]-1-Hydroxy-Ethyl}-6,9-Dioxo-2-Oxa-7,10-Diaza-Bicyclo[11.2.2]Heptadeca-1(16),13(17),14-Trien-8-Yl)-Acetamide, Inhibitor 2
Experimental
Matched Name: … Hydroxy-Ethyl}-6,9-Dioxo-2-Oxa-7,10-Diaza-Bicyclo[11.2.2]Heptadeca-1(16),13(17),14-Trien-8-Yl)-Acetamide, Inhibitor …
Spebrutinib
Spebrutinib has been used in trials studying the treatment of Rheumatoid Arthritis, Lymphoma, Large B-Cell, Diffuse, and Leukemia Lymphocytic Chronic B-Cell.
Investigational
Matched Synonyms: … BTK inhibitor CC-292 …
AVID-200
AVID-200 is an Anti-transforming growth factor beta (TGF-β) trap fusion protein.
Investigational
Matched Synonyms: … Tgf-beta 1/3 inhibitor avid200 …
Unesbulin
Investigational
Matched Synonyms: … Bmi1 inhibitor ptc596 ... Polycomb ring finger oncogene inhibitor ptc596 …
ZM-39923
ZM-39923 is a small molecule that inhibits Janus kinase and human tissue transglutaminase (TGM2).
Investigational
Matched Synonyms: … Jak3 inhibitor iv …
Naporafenib
Naporafenib is under investigation in clinical trial NCT06346067 (A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With Nras-mutant Melanoma (SEACRAFT-2)).
Investigational
Matched Synonyms: … Pan-raf inhibitor lxh254 …
Supinoxin
Supinoxin is under investigation in clinical trial NCT02003092 (RX-5902 Treatment of Subjects With Triple Negative Breast Cancer).
Investigational
Matched Synonyms: … P-p68 inhibitor rx-5902 …
Displaying drugs 751 - 775 of 1291 in total