Displaying drugs 7751 - 7775 of 8356 in total
Sodium dichloroacetate
Investigational
Siagoside
Siagoside (Sygen, AGF 2) has been investigated for the treatment of Parkinson Disease. It is a naturally occurring substance in the nerve cell’s membrane that is thought to play a role in cell growth, development, and repair. Siagoside completed phase 2 trials for parkinson's disease (PD) treatment. Sygen appears to...
Investigational
Matched Iupac: … N-[(2S,3R,4E)-1-{[(2R,3R,4R,5S,6R)-5-[(2S,4S,4'aR,5R,5'S,6R,7'R,8'S,8'aS)-5-acetamido-8'-{[(2S,3R,4R, ... 5R,6R)-3-acetamido-5-hydroxy-6-(hydroxymethyl)-4-{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl ... -oneoxy]-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3-hydroxyoctadec-4-en-2-yl]octadecanamide ... hydroxymethyl)-6-[(1R,2R)-1,2,3-trihydroxypropyl]-hexahydrospiro[oxane-2,2'-pyrano[3,4-b][1,4]dioxin]-3' …
Naporafenib
Naporafenib is under investigation in clinical trial NCT06346067 (A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With Nras-mutant Melanoma (SEACRAFT-2)).
Investigational
Matched Synonyms: … N-(3-(2-(hydroxyethoxy)-6-(morpholin-4-yl) pyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)pyridine- ... 4-pyridinecarboxamide, n-(3-(2-(2-hydroxyethoxy)-6-(4-morpholinyl)-4-pyridinyl)-4-methylphenyl)-2-(trifluoromethyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
2-Amino-3-(Cystein-S-Yl)-Isoxazolidin-5-Yl-Acetic Acid
Experimental
Matched Name: … 2-Amino-3-(Cystein-S-Yl)-Isoxazolidin-5-Yl-Acetic Acid …
Matched Iupac: … (2R)-2-amino-3-{[(3R,5R)-5-[(S)-amino(carboxy)methyl]-1,2-oxazolidin-3-yl]sulfanyl}propanoic acid …
Matched Iupac: … (2R)-2-amino-3-{[(3R,5R)-5-[(S)-amino(carboxy)methyl]-1,2-oxazolidin-3-yl]sulfanyl}propanoic acid …
4-(Acetylamino)-3-[(Hydroxyacetyl)Amino]Benzoic Acid
Experimental
Matched Name: … 4-(Acetylamino)-3-[(Hydroxyacetyl)Amino]Benzoic Acid …
Matched Iupac: … 4-acetamido-3-(2-hydroxyacetamido)benzoic acid …
Matched Iupac: … 4-acetamido-3-(2-hydroxyacetamido)benzoic acid …
N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE
Experimental
Matched Name: … N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE …
Matched Iupac: … 2-[(4-hydroxy-8-iodoisoquinolin-3-yl)formamido]acetic acid …
Matched Iupac: … 2-[(4-hydroxy-8-iodoisoquinolin-3-yl)formamido]acetic acid …
Des(carbamimidoyl) zanamivir
Experimental
Matched Iupac: … (2R,3R,4S)-4-amino-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Cilomilast
Cilomilast (Ariflo, SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD). It is orally active and acts as a selective Phosphodiesterase-4 inhibitor. Following four clinical trials, the drug proved to be effective in treating COPD, however it...
Investigational
Matched Synonyms: … cis-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphenyl)cyclohexanecarboxylic acid …
Matched Iupac: … (1s,4s)-4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid …
Matched Iupac: … (1s,4s)-4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid …
(R)-Rolipram
The (R)-enantiomer of rolipram, it is a phosphodiesterase inhibitor with antidepressant properties.
Experimental
Matched Synonyms: … (R)-4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolidin-2-one …
Matched Iupac: … (4R)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one …
Matched Iupac: … (4R)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one …
Empegfilgrastim
Empegfilgrastim is under investigation in clinical trial NCT01569087 (Dose-finding Study of Empegfilgrastim for Neutropenia Prophylaxis in Patients With Breast Cancer).
Investigational
2-(p-Tolyl)ethyl nicotinate
Experimental
Matched Synonyms: … 3-pyridinecarboxylic acid, 2-(4-methylphenyl)ethyl ester
…
DCVAC/OvCa
DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Tarenflurbil
Tarenflurbil is an investigational drug that was studied in patients with mild Alzheimer's disease. It is a selective amyloid lowering agent (SALA) that reduces levels of the toxic peptide amyloid beta 42 (Aβ42) in cultured human cells and in animal models. Aβ42 is the primary initiator of neurotoxicity and amyloid...
Investigational
Tetrafluoroborate
Tetrafluoroborate is under investigation in clinical trial NCT02907073 (Positron Emission Tomography (PET) Imaging Studies With NIS Reporter).
Investigational
Matched Synonyms: … Borate(1-), tetrafluoro- ... Tetrafluoroborate(1-) …
VIS-410
VIS-410 is under investigation in clinical trial NCT03040141 (Study of Efficacy and Safety of IV VIS410 Plus Oseltamivir Versus Oseltamivir in Hospitalized Adults With Influenza A).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(INFLUENZA HEMAGGLUTININ) (HUMAN MONOCLONAL VIS410 .GAMMA.1-CHAIN), DISULFIDE …
Ravidasvir
Ravidasvir is under investigation in clinical trial NCT02961426 (Sofosbuvir Plus Ravidasvir for the Treatment of HCV Chronic Infection).
Investigational
Matched Iupac: … -2-yl]-1H-1,3-benzodiazol-5-yl}naphthalen-2-yl)-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan ... methyl N-[(2S)-1-[(2S)-2-[4-(6-{2-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl]pyrrolidin …
Pyrrolidine
Investigational
Matched Synonyms: … 1-Azacyclopentane …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
6-Hydro-1-Methyladenosine-5'-Monophosphate
Experimental
Matched Name: … 6-Hydro-1-Methyladenosine-5'-Monophosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-imino-1-methyl-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methoxy}phosphonic …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-imino-1-methyl-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methoxy}phosphonic …
1-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANE
Experimental
Matched Name: … 1-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANE …
Matched Iupac: … 8-[(hydroxymethyl)amino]octan-1-ol …
Matched Iupac: … 8-[(hydroxymethyl)amino]octan-1-ol …
Displaying drugs 7751 - 7775 of 8356 in total