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Displaying drugs 7801 - 7825 of 11073 in total
Diguanosine-5'-Triphosphate
Experimental
Matched Name: … Diguanosine-5'-Triphosphate …
Matched Iupac: … bis[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
Matched Iupac: … bis[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
3'-THIO-THYMIDINE-5'-PHOSPHATE
Experimental
Matched Name: … 3'-THIO-THYMIDINE-5'-PHOSPHATE …
Matched Iupac: … {[(2R,3S,5R)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-sulfanyloxolan-2-yl]methoxy}phosphonic …
Matched Iupac: … {[(2R,3S,5R)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-sulfanyloxolan-2-yl]methoxy}phosphonic …
Belagenpumatucel-L (NCI H-520)
Investigational
AMT-130
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 5 encoding a microRNA targeted to human Huntingtin gene …
Exon 55 specific phosphorothioate oligonucleotide
Investigational
2'-Deoxyuridine
2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies. [PubChem]
Experimental
Matched Name: … 2'-Deoxyuridine …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … 2'-Deoxyuridine. …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … 2'-Deoxyuridine. …
2'-Deoxymaltose
Experimental
Matched Name: … 2'-Deoxymaltose …
Matched Iupac: … (2R,3R,4S,5S,6R)-2-{[(2R,3S,4R,6S)-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane …
Matched Iupac: … (2R,3R,4S,5S,6R)-2-{[(2R,3S,4R,6S)-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane …
2-fluorofucose
2-fluorofucose is under investigation in clinical trial NCT02952989 (A Safety Study of SGN-2FF for Patients With Advanced Solid Tumors).
Investigational
Matched Name: … 2-fluorofucose …
Matched Iupac: … (2S,3R,4R,5S)-2-fluoro-3,4,5-trihydroxyhexanal …
Matched Description: … 2-fluorofucose is under investigation in clinical trial NCT02952989 (A Safety Study of SGN-2FF for Patients …
Matched Iupac: … (2S,3R,4R,5S)-2-fluoro-3,4,5-trihydroxyhexanal …
Matched Description: … 2-fluorofucose is under investigation in clinical trial NCT02952989 (A Safety Study of SGN-2FF for Patients …
Arylomycin A2
Experimental
Matched Iupac: … (8S,11S,14S)-14-{2-[(2R)-2-[(2R)-2-(N,10-dimethylundecanamido)-3-hydroxypropanamido]propanamido]-N-methylacetamido ... }-3,18-dihydroxy-11-methyl-10,13-dioxo-9,12-diazatricyclo[13.3.1.1^{2,6}]icosa-1(18),2(20),3,5,15(19) …
2-oxopropyl-CoM
Experimental
Matched Synonyms: … 2-(2-Oxopropylthio)ethanesulfonate ... 2-[(2-Oxopropyl)sulfanyl]ethanesulfonic acid ... 2-ketopropyl-CoM …
Matched Name: … 2-oxopropyl-CoM …
Matched Iupac: … 2-[(2-oxopropyl)sulfanyl]ethane-1-sulfonic acid …
Matched Name: … 2-oxopropyl-CoM …
Matched Iupac: … 2-[(2-oxopropyl)sulfanyl]ethane-1-sulfonic acid …
HSV-2 theracine
HSV-2 theracine is an attenuated recombinant vaccine developed by AuRx for the treatment of genital herpes.
Investigational
Matched Name: … HSV-2 theracine …
Matched Description: … HSV-2 theracine is an attenuated recombinant vaccine developed by AuRx for the treatment of genital herpes …
Matched Description: … HSV-2 theracine is an attenuated recombinant vaccine developed by AuRx for the treatment of genital herpes …
2-deoxyglucose
2-deoxyglucose is predominantly used as a diagnostic agent in its radiolabelled form (fluorine-18 is used as the radiolabel). By using positron emission tomography (PET), radiolabelled 2-deoxyglucose can determine glucose metabolism, which is altered in diseases such as cardiovascular disease, tumors, and Alzheimer's disease. Therapeutically, 2-deoxyglucose is an investigational drug that...
Experimental
Investigational
Matched Synonyms: … 2-DG ... 2-deoxy-D-glucose ... 2-Deoxy-D-arabino-hexose …
Matched Name: … 2-deoxyglucose …
Matched Description: … approved indication for 2-deoxyglucose as a therapeutic agent. ... 2-deoxyglucose is predominantly used as a diagnostic agent in its radiolabelled form (fluorine-18 is ... Therapeutically, 2-deoxyglucose is an investigational drug that is being studied as an anticancer and …
Matched Name: … 2-deoxyglucose …
Matched Description: … approved indication for 2-deoxyglucose as a therapeutic agent. ... 2-deoxyglucose is predominantly used as a diagnostic agent in its radiolabelled form (fluorine-18 is ... Therapeutically, 2-deoxyglucose is an investigational drug that is being studied as an anticancer and …
(2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate
Experimental
Matched Synonyms: … 1-Octadecyl-2-acetamido-2-deoxy-SN-glycerol-3-phosphoethylmethyl sulfide …
Matched Name: … (2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate …
Matched Iupac: … [(2R)-2-acetamido-3-(octadecyloxy)propoxy][2-(methylsulfanyl)ethoxy]phosphinic acid …
Matched Name: … (2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate …
Matched Iupac: … [(2R)-2-acetamido-3-(octadecyloxy)propoxy][2-(methylsulfanyl)ethoxy]phosphinic acid …
Sofituzumab vedotin
Sofituzumab vedotin is under investigation in clinical trial NCT01335958 (Safety and Pharmacokinetics of DMUC5754A Administered Intravenously to Patients With Platinum-Resistant Ovarian Cancer or Unresectable Pancreatic Cancer).
Investigational
Zeluvalimab
Zeluvalimab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational
(2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid
Experimental
Matched Name: … (2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid …
Matched Iupac: … (2S)-8-{[(tert-butoxy)carbonyl]amino}-2-(1H-indol-3-yl)octanoic acid …
Matched Iupac: … (2S)-8-{[(tert-butoxy)carbonyl]amino}-2-(1H-indol-3-yl)octanoic acid …
N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE
Experimental
Matched Name: … N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCINE …
Matched Iupac: … (2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]formamido}-3-methylpentanoic acid …
Matched Iupac: … (2S,3S)-2-{[(2S,3S)-3-(ethoxycarbonyl)oxiran-2-yl]formamido}-3-methylpentanoic acid …
Vapitadine
Vapitadine is an antihistamine that Barrier Therapeutics is developing as a treatment for allergic reactions of the skin, such as those associated with hives and for the itch associated with atopic dermatitis. An advantage of vapitadine over other antihistamines may be the absence of the sedation, even at high doses.
Investigational
Matched Iupac: … 4',7'-diazaspiro[piperidine-4,2'-tricyclo[8.4.0.0^{3,7}]tetradecane]-1'(10'),3',5',11',13'-pentaene-6 …
CP-609754
LNK 754 has been investigated in Mild Alzheimer's Disease.
Investigational
Matched Iupac: … 6-[(R)-(4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-ethynylphenyl)-1-methyl-1,2-dihydroquinolin ... -2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Aloe vera leaf
Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands. Aloe vera, or Aloe barbadensis miller, is the most common species of Aloe that is cultivated for agricultural and medical purposes. It is a perennial succulent xerophyte with elongated...
Experimental
Matched Description: … Common active polysaccharides include glucomannans, polymannose, and acemannan, or b-(1–4)-acetylated …
Molnupiravir
Molnupiravir (EIDD-2801, MK-4482) is the isopropylester prodrug of N4-hydroxycytidine.[A193014,A193026] With improved oral bioavailability in non-human primates, it is hydrolyzed in vivo, and distributes into tissues where it becomes the active 5’-triphosphate form. The active drug incorporates into the genome of RNA viruses, leading to an accumulation of mutations known as...
Investigational
Matched Iupac: … [(2R,3S,4R,5R)-3,4-dihydroxy-5-[(4Z)-4-(hydroxyimino)-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl]oxolan-2 ... -yl]methyl 2-methylpropanoate …
Matched Description: … non-human primates, it is hydrolyzed _in vivo_, and distributes into tissues where it becomes the active 5’ ... studies have shown molnupiravir inhibits replication of human and bat coronaviruses, including SARS-CoV-2, ... Molnupiravir was granted approval by the UK's Medicines and Health products Regulatory Agency (MHRA) on 4 …
Matched Description: … non-human primates, it is hydrolyzed _in vivo_, and distributes into tissues where it becomes the active 5’ ... studies have shown molnupiravir inhibits replication of human and bat coronaviruses, including SARS-CoV-2, ... Molnupiravir was granted approval by the UK's Medicines and Health products Regulatory Agency (MHRA) on 4 …
7beta-hydroxycholesterol
Experimental
Matched Synonyms: … (3β,7β)-cholest-5-ene-3,7-diol …
Matched Iupac: … (1R,3aS,3bS,4R,7S,9aR,9bS,11aR)-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H,6H,7H …
Matched Iupac: … (1R,3aS,3bS,4R,7S,9aR,9bS,11aR)-9a,11a-dimethyl-1-[(2R)-6-methylheptan-2-yl]-1H,2H,3H,3aH,3bH,4H,6H,7H …
Dichlororibofuranosylbenzimidazole
Experimental
Matched Iupac: … (2R,3R,4S,5R)-2-(5,6-dichloro-1H-1,3-benzodiazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol …
Displaying drugs 7801 - 7825 of 11073 in total