Displaying drugs 7901 - 7925 of 13185 in total
Zimberelimab
Investigational
Matched Synonyms: … Anti-pd-1 monoclonal antibody gls-010 ... Immunoglobulin g4(231-proline), anti-(human programmed cell death protein 1) (human monoclonal ab122 …
Tofogliflozin
Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type 2.
Investigational
Matched Iupac: … (1S,3'R,4'S,5'S,6'R)-6-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)-3H-spiro[2-benzofuran-1,2'-oxane]-3 …
Matched Description: … 2. ... Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors …
Matched Description: … 2. ... Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors …
Alvelestat
Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … N-[(5-methanesulfonylpyridin-2-yl)methyl]-6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-2-oxo-1-[3-(trifluoromethyl ... )phenyl]-1,2-dihydropyridine-3-carboxamide …
Matched Description: … Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ravoxertinib
Ravoxertinib is under investigation in clinical trial NCT01875705 (A Dose-Escalation Study of GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors).
Investigational
Matched Iupac: … -yl}-1,2-dihydropyridin-2-one ... 1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-{2-[(1-methyl-1H-pyrazol-5-yl)amino]pyrimidin-4 …
Matched Description: … Ravoxertinib is under investigation in clinical trial NCT01875705 (A Dose-Escalation Study of GDC-0994 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Ravoxertinib is under investigation in clinical trial NCT01875705 (A Dose-Escalation Study of GDC-0994 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fonadelpar
Fonadelpar is under investigation in clinical trial NCT03527212 (A Study to Assess the Safety and Effectiveness of SJP-0035 for the Treatment of Patients With Dry Eye Disease).
Investigational
Matched Iupac: … 2-[(5-methyl-3-{2-[4-(propan-2-yl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]ethyl}-1,2-benzoxazol …
Matched Description: … SJP-0035 for the Treatment of Patients With Dry Eye Disease). ... is under investigation in clinical trial NCT03527212 (A Study to Assess the Safety and Effectiveness of …
Matched Description: … SJP-0035 for the Treatment of Patients With Dry Eye Disease). ... is under investigation in clinical trial NCT03527212 (A Study to Assess the Safety and Effectiveness of …
7,8-Dihydroxy-1-Methoxy-3-Methyl-10-Oxo-4,10-Dihydro-1h,3h-Pyrano[4,3-B]Chromene-9-Carboxylic Acid
Experimental
Matched Name: … 7,8-Dihydroxy-1-Methoxy-3-Methyl-10-Oxo-4,10-Dihydro-1h,3h-Pyrano[4,3-B]Chromene-9-Carboxylic Acid …
Matched Iupac: … (1R,3S)-7,8-dihydroxy-1-methoxy-3-methyl-10-oxo-1H,3H,4H,10H-pyrano[4,3-b]chromene-9-carboxylic acid …
Matched Iupac: … (1R,3S)-7,8-dihydroxy-1-methoxy-3-methyl-10-oxo-1H,3H,4H,10H-pyrano[4,3-b]chromene-9-carboxylic acid …
Immucillin-G
Experimental
Matched Synonyms: … (1S)-1,4-dideoxy-1,4-imino-1-(9-deazaguanin-9-yl)-D-ribitol …
Matched Iupac: … 2-amino-7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-3H,4H,5H-pyrrolo[3,2-d]pyrimidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2-amino-7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-3H,4H,5H-pyrrolo[3,2-d]pyrimidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE
Experimental
Matched Iupac: … (2R,3R,4S,5R)-2-{4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-methyloxolane-3,4-diol …
Narsoplimab
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … (1-445) (HOMO SAPIENS VH (IGHV2-26*01 (94%) (IGHD)-I ... MASP-2 antibody ... ANTI-MASP-2 MONOCLONAL ANTIBODY OMS721 …
Matched Description: … [A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in ... thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of ... A241050] Narsoplimab is under investigation in clinical trial NCT03205995 (Safety and Efficacy Study of …
Matched Description: … [A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in ... thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of ... A241050] Narsoplimab is under investigation in clinical trial NCT03205995 (Safety and Efficacy Study of …
Aceprometazine
Aceprometazine is a is a drug with neuroleptic and anti-histamine properties. Although not widely prescribed, it is used in combination with meprobamate for the treatment of sleep disorders in France under the trade name Mepronizine.
Experimental
Matched Synonyms: … 10-(2-(Dimethylamino)propyl)phenothiazin-2-yl methyl ketone …
Matched Iupac: … 1-{10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl}ethan-1-one …
Matched Description: … Although not widely prescribed, it is used in combination with meprobamate for the treatment of sleep …
Matched Iupac: … 1-{10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl}ethan-1-one …
Matched Description: … Although not widely prescribed, it is used in combination with meprobamate for the treatment of sleep …
Nendratareotide uzatansine
Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated to the cytotoxin mertansine.
Investigational
Matched Synonyms: … Peptide-drug conjugate combining [(Tyr3,Cys8) octreotate amide] and N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl …
Matched Description: … Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated …
Matched Description: … Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated …
Cytidine-5'-Triphosphate
Cytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety. [PubChem]
Experimental
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
N,O6-Disulfo-Glucosamine
Experimental
Matched Iupac: … {[(2R,3S,4R,5R,6S)-3,4,6-trihydroxy-5-(sulfoamino)oxan-2-yl]methoxy}sulfonic acid …
Geneticin
Geneticin (also known as G418) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells and is commonly used in laboratory research to select genetically engineered cells. Resistance to Geneticin is...
Experimental
Matched Iupac: … yl]oxy}-2-hydroxycyclohexyl]oxy}-2-[(1R)-1-hydroxyethyl]oxane-3,4-diol ... amino-6-{[(1R,2S,3S,4R,6S)-4,6-diamino-3-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)oxan-2- …
ARX201
ARX201 (PEG-ahGH) is a recombinant form of human growth hormone that has been modified using Ambrx’s patented ReCODE™ technology to achieve precise spatial positioning of the site of polyethylene glycol (PEG) attachment to human growth hormone, by biosynthetic incorporation of a chemically unique amino acid (ahGH). ARX201 has improved pharmacological...
Investigational
Matched Description: … patented ReCODE™ technology to achieve precise spatial positioning of the site of polyethylene glycol ... ARX201 (PEG-ahGH) is a recombinant form of human growth hormone that has been modified using Ambrx’s ... (PEG) attachment to human growth hormone, by biosynthetic incorporation of a chemically unique amino …
VIR201
is an experimental therapeutic vaccine currently in clinical trial. The aim of therapeutic vaccines is to augment the body's immune response to HIV and to delay or prevent progression to AIDS.
Investigational
Matched Description: … The aim of therapeutic vaccines is to augment the body's immune response to HIV and to delay or prevent …
LY-2452473
Ly2452473 is under investigation for the supportive care of Prostate Cancer. Ly2452473 has been investigated for the treatment of Erectile Dysfunction.
Investigational
Matched Iupac: … propan-2-yl N-[(2S)-7-cyano-4-[(pyridin-2-yl)methyl]-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]carbamate …
Matched Description: … Ly2452473 is under investigation for the supportive care of Prostate Cancer. ... Ly2452473 has been investigated for the treatment of Erectile Dysfunction. …
Matched Description: … Ly2452473 is under investigation for the supportive care of Prostate Cancer. ... Ly2452473 has been investigated for the treatment of Erectile Dysfunction. …
LY-2624803
LY-2624803 is under investigation in clinical trial NCT01236105 (Effect of Activated Charcoal and Time of Dose on the Pharmacokinetics of LY2624803 in Healthy Subject).
Investigational
Matched Iupac: … 2,2-dimethyl-3-(4-{2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-10-yl}piperazin ... -1-yl)propanoic acid …
Matched Description: … of Dose on the Pharmacokinetics of LY2624803 in Healthy Subject). ... LY-2624803 is under investigation in clinical trial NCT01236105 (Effect of Activated Charcoal and Time …
Matched Description: … of Dose on the Pharmacokinetics of LY2624803 in Healthy Subject). ... LY-2624803 is under investigation in clinical trial NCT01236105 (Effect of Activated Charcoal and Time …
LY-2623091
LY-2623091 is under investigation in clinical trial NCT02194465 (A Study of LY2623091 in Participants With High Blood Pressure).
Investigational
Matched Iupac: … -[(2R)-1-(morpholin-4-yl)propan-2-yl]-1H-1,3-benzodiazol-2-yl)urea ... (5-{[(2E)-6-fluoro-9-oxatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene]methyl}-1 …
Matched Description: … LY-2623091 is under investigation in clinical trial NCT02194465 (A Study of LY2623091 in Participants …
Matched Description: … LY-2623091 is under investigation in clinical trial NCT02194465 (A Study of LY2623091 in Participants …
GRAd-COV2
GRAd-COV2 is a COVID-19 vaccine candidate being developed by ReiThera[L30420, L30423]. This therapy is based on a novel replication-incompetent simian adenoviral vector that encodes the full-length SARS-CoV-2 spike protein (GRAd-COV2)[L30420, L30423]. Preclinical and clinical studies show GRAd-COV2 to induce robust cellular and humoral immune responses .
Investigational
Matched Description: … based on a novel replication-incompetent simian adenoviral vector that encodes the full-length SARS-CoV-2 …
ALM201
ALM201 is an anti-angiogenic synthetic peptide identified from the endogenous human protein, FKBPL. It is being investigated in the treatment of various cancers.
Investigational
Matched Description: … It is being investigated in the treatment of various cancers.[A254556] …
FLT201
FLT201 is a recombinant adeno-associated viral vector serotype S3 containing codon optimised expression cassette encoding human beta (β)-glucocerebrosidase variant 85 (GCasevar85)
Investigational
N-Allyl-6-{[3-(4-bromophenyl)-1-methyl-1H-indazol-6-yl]oxy}-N-methyl-1-hexanamine
Experimental
Matched Name: … N-Allyl-6-{[3-(4-bromophenyl)-1-methyl-1H-indazol-6-yl]oxy}-N-methyl-1-hexanamine …
Matched Iupac: … (6-{[3-(4-bromophenyl)-1-methyl-1H-indazol-6-yl]oxy}hexyl)(methyl)(prop-2-en-1-yl)amine …
Matched Iupac: … (6-{[3-(4-bromophenyl)-1-methyl-1H-indazol-6-yl]oxy}hexyl)(methyl)(prop-2-en-1-yl)amine …
N,N-DIETHYL-2-[(2-THIENYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
Experimental
Matched Name: … N,N-DIETHYL-2-[(2-THIENYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE …
Matched Iupac: … N,N-diethyl-2-(thiophene-2-amido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide …
Matched Iupac: … N,N-diethyl-2-(thiophene-2-amido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide …
Displaying drugs 7901 - 7925 of 13185 in total