Displaying drugs 7951 - 7975 of 11699 in total
Rotigaptide
Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease.
Investigational
Matched Iupac: … (2R)-N-(carbamoylmethyl)-2-(2-{[(2R,4S)-1-[(2R)-1-[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]pyrrolidine ... -2-carbonyl]-4-hydroxypyrrolidin-2-yl]formamido}acetamido)propanamide …
JTK-853
JTK-853 has been used in trials studying the treatment of Hepatitis C Virus Infection, Response to Therapy of.
Investigational
Matched Iupac: … }-1-[4-(trifluoromethyl)benzenesulfonyl]piperazine-2-carboxamide ... (2R)-4-{5-cyclopropyl-[1,3]thiazolo[4,5-d]pyrimidin-2-yl}-N-{[3-fluoro-4-(trifluoromethoxy)phenyl]methyl …
Molnupiravir
Molnupiravir (EIDD-2801, MK-4482) is the isopropylester prodrug of N4-hydroxycytidine.[A193014,A193026] With improved oral bioavailability in non-human primates, it is hydrolyzed in vivo, and distributes into tissues where it becomes the active 5’-triphosphate form. The active drug incorporates into the genome of RNA viruses, leading to an accumulation of mutations known as...
Investigational
Matched Iupac: … -yl]methyl 2-methylpropanoate ... [(2R,3S,4R,5R)-3,4-dihydroxy-5-[(4Z)-4-(hydroxyimino)-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl]oxolan-2 …
Matched Description: … studies have shown molnupiravir inhibits replication of human and bat coronaviruses, including SARS-CoV-2, …
Matched Description: … studies have shown molnupiravir inhibits replication of human and bat coronaviruses, including SARS-CoV-2, …
Trichloroacetaldehyde
Experimental
Gebasaxturev
Investigational
RH-1
RH-1 has been used in trials studying the treatment of Advanced Solid Tumors and Non-Hodgkin's Lymphoma.
Experimental
Investigational
Bis(2,2-dimethylpropanoyloxymethyl) VK-0214
Investigational
2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide
Experimental
4-Nitrocatechol
Experimental
N-(4-sulfamoylphenyl)-1H-indazole-3-carboxamide
Experimental
Encenicline
Encenicline has been investigated for the treatment of Cognition, Schizophrenia, Alzheimer's Disease, Cardiac Repolarization, and Central Nervous System Diseases.
Investigational
Matched Iupac: … N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-7-chloro-1-benzothiophene-2-carboxamide …
Ginsenoside C
Nutraceutical
Matched Iupac: … -trihydroxyoxan-2-yl]oxy}methyl)oxan-2-yl]oxy}hept-5-en-2-yl]tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan- ... (2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-{[(1R,2R,5S,7R,10R,11R,14S,15R,16R)-16-hydroxy- ... 2,6,6,10,11-pentamethyl-14-[(2S)-6-methyl-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3R,4S,5S)-3,4,5 …
K201 free base
Experimental
Investigational
Heptane-1,2,3-Triol
Experimental
MVA-mBN226B
Investigational
(-)-beta-Elemene
Investigational
Matched Iupac: … (1S,2S,4R)-1-ethenyl-1-methyl-2,4-bis(prop-1-en-2-yl)cyclohexane …
Sofalcone
Sofalcone is a mucosal protective agent that has been reported to inhibit growth of Helicobacter pylori. on adherence, production of vacuolating toxin (VT), and induction of interleukin-8 (IL-8) secretion by H. pylori.
Investigational
Matched Iupac: … 2-{5-[(3-methylbut-2-en-1-yl)oxy]-2-[(2E)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl]phenoxy …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Custirsen
Custirsen is a benzopyran with potential antineoplastic activity. Custirsen acts as a selective estrogen receptor modulator (SERM), inhibiting the proliferation of estrogen-sensitive breast cancer cells. This agent also inhibits growth and induces apoptosis of glioblastoma cells via a mechanism independent of estrogen receptor-related mechanisms. Custirsen is also being investigated in...
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Pictilisib
Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others.
Investigational
Matched Iupac: … 4-{6-[(4-methanesulfonylpiperazin-1-yl)methyl]-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl}-1H-indazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Cyprenorphine
Experimental
Illicit
Matched Iupac: … (1R,2R,6S,14R,15R,19R)-3-(cyclopropylmethyl)-19-(2-hydroxypropan-2-yl)-15-methoxy-13-oxa-3-azahexacyclo …
Vapitadine
Vapitadine is an antihistamine that Barrier Therapeutics is developing as a treatment for allergic reactions of the skin, such as those associated with hives and for the itch associated with atopic dermatitis. An advantage of vapitadine over other antihistamines may be the absence of the sedation, even at high doses.
Investigational
N-(4-{[amino(imino)methyl]amino}butyl)-2,4'-bi-1,3-thiazole-4-carboxamide
Experimental
Matched Iupac: … N-{4-[(diaminomethylidene)amino]butyl}-2-(1,3-thiazol-4-yl)-1,3-thiazole-4-carboxamide …
Displaying drugs 7951 - 7975 of 11699 in total