Displaying drugs 776 - 800 of 2518 in total
Meglutol
An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
Experimental
Matched Synonyms: … Dicrotalic acid ... 3-hydroxy-3-methylglutaric acid …
Matched Iupac: … 3-hydroxy-3-methylpentanedioic acid …
Matched Description: … An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids ... acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Iupac: … 3-hydroxy-3-methylpentanedioic acid …
Matched Description: … An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids ... acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Arsenous acid
Experimental
Investigational
Matched Synonyms: … arsenous acid ... arsorous acid …
Matched Name: … Arsenous acid …
Matched Iupac: … arsorous acid …
Matched Name: … Arsenous acid …
Matched Iupac: … arsorous acid …
Triethyl citrate
Investigational
Matched Synonyms: … Citric acid ethyl ester ... Citric acid triethyl ester …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Tricarboxylic Acids …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Tricarboxylic Acids …
Obeticholic acid
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … Obeticholic acid ... 6-ethylchenodeoxycholic acid ... 6α-ethylchenodeoxycholic acid …
Matched Name: … Obeticholic acid …
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Cholic Acids …
Matched Name: … Obeticholic acid …
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Cholic Acids …
Sinapic acid
Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. It is also a constituent of propolis.
Experimental
Matched Synonyms: … Sinapinic acid ... trans-sinapic acid ... (E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)-2-propenoic acid …
Matched Name: … Sinapic acid …
Matched Iupac: … (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid …
Matched Description: … Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. …
Matched Categories: … Indicators and Reagents ... Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … Sinapic acid …
Matched Iupac: … (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid …
Matched Description: … Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. …
Matched Categories: … Indicators and Reagents ... Carboxylic Acids ... Acids, Carbocyclic …
Sevelamer
Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Bile Acid Sequestrants …
Matched Products: … COAT-APRID …
Matched Products: … COAT-APRID …
Doconexent
A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. It is an omega-3 fatty acid and...
Approved
Investigational
Matched Synonyms: … cervonic acid ... Docosahexanoic Acid ... Docosahexaenoic acid …
Matched Iupac: … (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid …
Matched Description: … A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement ... It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin ... , and retina thus plays an important role in their development and function. …
Matched Mixtures name: … Taron-prex Prenatal ... Iron Polysaccharides Folic Acid DHA …
Matched Categories: … Fatty Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Unsaturated …
Matched Iupac: … (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid …
Matched Description: … A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement ... It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin ... , and retina thus plays an important role in their development and function. …
Matched Mixtures name: … Taron-prex Prenatal ... Iron Polysaccharides Folic Acid DHA …
Matched Categories: … Fatty Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Unsaturated …
4-(Dimethylamino)benzoic acid
Experimental
Matched Synonyms: … p-Dimethylamino benzoic acid ... N,N-Dimethyl-4-aminobenzoic acid ... N,N-Dimethyl-p-aminobenzoic acid …
Matched Name: … 4-(Dimethylamino)benzoic acid …
Matched Iupac: … 4-(dimethylamino)benzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Name: … 4-(Dimethylamino)benzoic acid …
Matched Iupac: … 4-(dimethylamino)benzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
3-hydroxyanthranilic acid
An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
Experimental
Matched Synonyms: … 3-Oxyanthranilic acid ... 2-Amino-3-hydroxy-benzoic acid ... 2-Amino-3-Hydroxybenzoic Acid …
Matched Name: … 3-hydroxyanthranilic acid …
Matched Iupac: … 2-amino-3-hydroxybenzoic acid …
Matched Description: … It may be a free radical scavenger and a carcinogen. …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Name: … 3-hydroxyanthranilic acid …
Matched Iupac: … 2-amino-3-hydroxybenzoic acid …
Matched Description: … It may be a free radical scavenger and a carcinogen. …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
N,N-dimethylglycine
Experimental
Matched Synonyms: … (dimethylamino)acetic acid ... 2-(Dimethylamino)acetic acid ... N,N-Dimethylaminoacetic acid …
Matched Iupac: … 2-(dimethylamino)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … 2-(dimethylamino)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Nitrilotriacetic acid
Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.)
Experimental
Matched Synonyms: … Triglycollamic acid ... nitrilo-2,2',2''-triacetic acid ... α,α',α''-trimethylaminetricarboxylic acid …
Matched Name: … Nitrilotriacetic acid …
Matched Iupac: … 2-[bis(carboxymethyl)amino]acetic acid …
Matched Description: … Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Nitrilotriacetic acid …
Matched Iupac: … 2-[bis(carboxymethyl)amino]acetic acid …
Matched Description: … Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acids, Acyclic ... Carboxylic Acids …
Aminohippuric acid
The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Synonyms: … Aminohippuric acid ... 4-aminohippuric acid ... p-aminohippuric acid …
Matched Name: … Aminohippuric acid …
Matched Iupac: … 2-[(4-aminophenyl)formamido]acetic acid …
Matched Description: … Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory ... The glycine amide of 4-aminobenzoic acid. …
Matched Categories: … Indicators and Reagents ... Benzamides and benzamide derivatives ... Tests for Renal Function and Ureteral Injuries ... Keto Acids ... Acids, Carbocyclic …
Matched Name: … Aminohippuric acid …
Matched Iupac: … 2-[(4-aminophenyl)formamido]acetic acid …
Matched Description: … Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory ... The glycine amide of 4-aminobenzoic acid. …
Matched Categories: … Indicators and Reagents ... Benzamides and benzamide derivatives ... Tests for Renal Function and Ureteral Injuries ... Keto Acids ... Acids, Carbocyclic …
Idroxioleic acid
Investigational
Matched Synonyms: … 2-hydroxyoleic acid ... Alpha-hydroxyoleic acid ... (z)-2-hydroxyoctadec-9-enoic acid …
Matched Name: … Idroxioleic acid …
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Matched Name: … Idroxioleic acid …
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Ketoprofen
Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Approved
Vet approved
Matched Synonyms: … 3-Benzoylhydratropic acid ... m-Benzoylhydratropic acid ... 2-(3-Benzoylphenyl)propionic acid …
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid …
Matched Description: … and antipyretic properties. ... Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid …
Matched Description: … and antipyretic properties. ... Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Clobetasol propionate
Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Description: … [L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described …
Matched Mixtures name: … Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% ... Ciclopirox Olamine 0.77% / Clobetasol Propionate 0.05% / Salicylic Acid 3%. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Clobetasol Propionate ANDA ... CLOBETASOL ACIS CREME ... CLOBETASOL ACIS SALBE …
Matched Mixtures name: … Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% ... Ciclopirox Olamine 0.77% / Clobetasol Propionate 0.05% / Salicylic Acid 3%. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Clobetasol Propionate ANDA ... CLOBETASOL ACIS CREME ... CLOBETASOL ACIS SALBE …
Aminooxyacetic acid
A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. [PubChem]
Experimental
Matched Synonyms: … aminoxyacetic acid ... (aminooxy)acetic acid …
Matched Name: … Aminooxyacetic acid …
Matched Iupac: … 2-(aminooxy)acetic acid …
Matched Description: … inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Aminooxyacetic acid …
Matched Iupac: … 2-(aminooxy)acetic acid …
Matched Description: … inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
beta-D-Galactopyranuronic acid
Experimental
Matched Synonyms: … β-D-galacturonic acid ... β-D-Galactopyranuronic acid …
Matched Name: … beta-D-Galactopyranuronic acid …
Matched Iupac: … (2S,3R,4S,5R,6R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid …
Matched Name: … beta-D-Galactopyranuronic acid …
Matched Iupac: … (2S,3R,4S,5R,6R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid …
Dipicolinic acid
Experimental
Matched Synonyms: … 2,6-Dipicolinic acid ... 2,6-pyridinedicarboxylic acid …
Matched Name: … Dipicolinic acid …
Matched Iupac: … pyridine-2,6-dicarboxylic acid …
Matched Categories: … Acids, Heterocyclic …
Matched Name: … Dipicolinic acid …
Matched Iupac: … pyridine-2,6-dicarboxylic acid …
Matched Categories: … Acids, Heterocyclic …
Necuparanib
Necuparanib is under investigation in clinical trial NCT01621243 (M402 in Combination With Nab-paclitaxel and Gemcitabine in Pancreatic Cancer).
Investigational
Matched Synonyms: … M402 free acid ... M-402 free acid …
Matched Description: … Necuparanib is under investigation in clinical trial NCT01621243 (M402 in Combination With Nab-paclitaxel and …
Matched Description: … Necuparanib is under investigation in clinical trial NCT01621243 (M402 in Combination With Nab-paclitaxel and …
Sebacic acid
Experimental
Matched Synonyms: … Decanedioic acid ... 1,10-decanedioic acid …
Matched Name: … Sebacic acid …
Matched Iupac: … decanedioic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Sebacic acid …
Matched Iupac: … decanedioic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids …
Propanoic acid
Sodium propionate is the sodium salt of propionic acid that exists as colorless, transparent crystals or a granular crystalline powder. It is considered generally recognized as safe (GRAS) food ingredient by FDA, where it acts as an antimicrobial agent for food preservation and flavoring agent. Its use as a food...
Approved
Vet approved
Matched Synonyms: … Propionic acid …
Matched Name: … Propanoic acid …
Matched Iupac: … propanoic acid …
Matched Description: … as safe (GRAS) food ingredient by FDA, where it acts as an antimicrobial agent for food preservation and ... Sodium propionate is is prepared by neutralizing propionic acid with sodium hydroxide. ... Sodium propionate is the sodium salt of propionic acid that exists as colorless, transparent crystals …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Name: … Propanoic acid …
Matched Iupac: … propanoic acid …
Matched Description: … as safe (GRAS) food ingredient by FDA, where it acts as an antimicrobial agent for food preservation and ... Sodium propionate is is prepared by neutralizing propionic acid with sodium hydroxide. ... Sodium propionate is the sodium salt of propionic acid that exists as colorless, transparent crystals …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
L-Gluconic Acid
Experimental
Matched Synonyms: … Xylosecarboxylic acid …
Matched Name: … L-Gluconic Acid …
Matched Iupac: … (2S,3S,4R,5S)-2,3,4,5,6-pentahydroxyhexanoic acid …
Matched Name: … L-Gluconic Acid …
Matched Iupac: … (2S,3S,4R,5S)-2,3,4,5,6-pentahydroxyhexanoic acid …
Ioglycamic acid
Experimental
Matched Synonyms: … Ioglycamic acid …
Matched Name: … Ioglycamic acid …
Matched Iupac: … 3-(2-{[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]methoxy}acetamido)-2,4,6-triiodobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... ioglycamic acid ... Triiodobenzoic Acids …
Matched Name: … Ioglycamic acid …
Matched Iupac: … 3-(2-{[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]methoxy}acetamido)-2,4,6-triiodobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... ioglycamic acid ... Triiodobenzoic Acids …
Piromidic acid
Experimental
Matched Synonyms: … Piromidic acid …
Matched Name: … Piromidic acid …
Matched Iupac: … 8-ethyl-5-oxo-2-(pyrrolidin-1-yl)-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxylic acid …
Matched Categories: … Acids, Heterocyclic ... Nicotinic Acids ... piromidic acid …
Matched Name: … Piromidic acid …
Matched Iupac: … 8-ethyl-5-oxo-2-(pyrrolidin-1-yl)-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxylic acid …
Matched Categories: … Acids, Heterocyclic ... Nicotinic Acids ... piromidic acid …
Butedronic acid
Experimental
Matched Synonyms: … Butedronic acid …
Matched Name: … Butedronic acid …
Matched Iupac: … 2-(diphosphonomethyl)butanedioic acid …
Matched Name: … Butedronic acid …
Matched Iupac: … 2-(diphosphonomethyl)butanedioic acid …
Displaying drugs 776 - 800 of 2518 in total