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Displaying drugs 776 - 800 of 5418 in total
Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 ... DNA, D(P-THIO)(C-T-A-T-C-T-RGM-RUM-M5C-C7G-T-T-C-T-C-T-RGM-RUM) ... ALL-P-AMBO-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5 …
Matched Description: … Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients …
Matched Salts cas: … 1613607-40-1
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of...
Approved
Investigational
Withdrawn
Matched International brands: … OraDisc A
Matched Synonyms: … 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid
Matched Iupac: … 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid
Matched Description: … and rhinitis. ... aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and ... Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. …
Matched Categories: … Alimentary Tract and Metabolism ... Heterocyclic Compounds, 1-Ring …
2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a is under investigation in clinical trial NCT01668823 (Photodynamic Therapy in Treating Patients With Lung Cancer).
Investigational
Matched Synonyms: … 3-PHORBINEPROPANOIC ACID, 14-ETHYL-9-(1-(HEXYLOXY)ETHYL)-4,8,13,18-TETRAMETHYL-20-OXO-, (3S,4S)- …
Matched Name: … 2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a
Matched Iupac: … 22-yl]propanoic acid ... 3-[(21S,22S)-11-ethyl-16-[1-(hexyloxy)ethyl]-12,17,21,26-tetramethyl-4-oxo-7,23,24,25-tetraazahexacyclo ... [18.2.1.1^{5,8}.1^{10,13}.1^{15,18}.0^{2,6}]hexacosa-1(23),2(6),5(26),8,10(25),11,13,15,17,19-decaen- …
Matched Description: … 2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a is under investigation in clinical trial NCT01668823 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK). In such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, induced by radiation treatment and by some cytotoxic drugs.
Investigational
Matched Synonyms: … 1-(2,4-dichlorbenzyl)-indazole-3-carboxylic acid ... diclondazolic acid
Matched Iupac: … 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid
Matched Description: … induced by radiation treatment and by some cytotoxic drugs. ... Lonidamine (LND) is a drug that interferes with energy metabolism of cancer cells, principally inhibiting ... In such way LND could impair energy-requiring processes, as recovery from potentially lethal damage, …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 1-Ring …
Experimental
Matched Synonyms: … 2,3-Dimercaptopropanesulfonic acid ... 2,3-Dimercapto-1-propane sulfonate ... 2,3-Dimercaptopropan-1-sulfonsaeure …
Matched Name: … 2,3-Dimercapto-1-propanesulfonic acid
Matched Iupac: … 2,3-disulfanylpropane-1-sulfonic acid
Matched Categories: … Compounds used in a research, industrial, or household setting …
Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for progressive supranuclear palsy. It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3). Tideglusib is being developed by the Spanish pharmaceutic company Zeltia...
Investigational
Withdrawn
Matched Synonyms: … 4-BENZYL-2-(A-NAPHTYL)-1,2,4-THIADIAZOLIDINE-3,5-DIONE ... 4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione …
Matched Iupac: … 4-benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione …
Matched Description: … It is reported to be a potent anti-inflammatory and neuroprotective that is a non-ATP competitive inhibitor ... Tideglusib is under the investigation for the development of treatments for Alzheimer's disease and for ... [A31601] Tideglusib is being developed by the Spanish pharmaceutic company Zeltia group and its current …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Bufexamac is a non-steroidal anti-inflammatory drug (NSAID) under the market name Droxaryl, Malipuran, Paraderm and Parfenac. It is typically administered topically for the treatment of subacute and chronic eczema of the skin, including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, and itching. It...
Approved
Withdrawn
Matched Synonyms: … Bufexamic acid ... 4-Butoxyphenylacetohydroxamic acid ... 2-(p-Butoxyphenyl)-acetohydroxamic acid
Matched Description: … and itching. ... including atopic eczema and other inflammatory dermatoses, as well as sunburn and other minor burns, ... , Paraderm and Parfenac. …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Hydroxy Acids
Approved
Matched Synonyms: … (57Co)Vitamin B12 …
Matched Iupac: … (57Co)cobalt(3+) (2R,3S,4S,6Z,8S,9S,11Z,14S,16Z,18R,19R)-4,9,14-tris(2-carbamoylethyl)-3,8,19-tris(carbamoylmethyl ... {7,10}.1^{12,15}]tricosa-5(23),6,10(22),11,15(21),16-hexaen-20-ide iminomethanide ... propyl]carbamoyl}ethyl)-2,3,6,8,13,13,16,18-octamethyl-20,21,22,23-tetraazapentacyclo[15.2.1.1^{2,5}.1^ ... )-18-(2-{[(2R)-2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-3H-1lambda4,3-benzodiazol-3-yl)-4-hydroxy-2-(hydroxymethyl …
Narasin is an agent with coccidiostatic and antibacterial properties.
Experimental
Vet approved
Matched Synonyms: … Narasin A
Matched Iupac: … ]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-3,5-dimethyloxan-2-yl]butanoic acid ... (2R)-2-[(2R,3S,5S,6R)-6-[(2S,3S,4S,6R)-6-[(2S,5S,7R,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-ethyl-5-hydroxy-6 ... -methyloxan-2-yl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5^{7}.3^{5}]pentadec-13-en-9-yl …
Matched Description: … Narasin is an agent with coccidiostatic and antibacterial properties. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Approved
Investigational
Matched Synonyms: … Vitamin BT ... 3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium hydroxide, inner salt …
Matched Description: … Constituent of striated muscle and liver. ... It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias …
Matched Salts cas: … 6645-46-1
Matched Mixtures name: … Protect Cardio AF ... Q 10 Suprabio +L-Carnitine …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Drugs that are Mainly Renally Excreted …
Matched Products: … T-KARNIT 1 G/10 ML ORAL ÇÖZELTI IÇEREN FLAKON, 10 ADET ... METACARTİN 100 MG/ML ŞURUP, 100 ML ... CARNITENE 1 ÇİĞNEME TABLETİ, 10 ADET …
Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Approved
Investigational
Matched Synonyms: … 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid ... p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid ... 4-[1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphtalenyl)ethenyl]benzoic acid
Matched Iupac: … 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid
Matched Description: … It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma. ... Bexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Compounds used in a research, industrial, or household setting …
Matched Products: … BEKSAR %1 JEL, 60 GRAM ... BEXATEN %1 JEL, 60 GRAM ... BEXGRATIN 75 MG YUMUŞAK KAPSÜL ,100 YUMUŞAK KAPSÜL …
Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. It presents excellent diagnostic properties to be used in positron emission tomography (PET) imaging. The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid transporter without incorporating in the metabolism within the...
Approved
Matched Synonyms: … (1R,3R)-1-amino-3(18F)fluorocyclobutane-1-carboxylic acid ... Anti-1-amino-3-(18F)fluorocyclobutane-1-carboxylic acid ... (18F)FACBC …
Matched Name: … Fluciclovine (18F) …
Matched Iupac: … (1r,3r)-1-amino-3-(¹⁸F)fluorocyclobutane-1-carboxylic acid
Matched Description: … Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. ... [A31385] Fluciclovine was developed by Blue Earth Diagnostics, Ltd. and FDA approved in May 27, 2016. ... [A31384] The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid
Matched Categories: … fluciclovine (18F) …
A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Approved
Matched Synonyms: … 1-hydroxy-α-phenylcyclopentaneacetic acid 2-(dimethylamino)ethyl ester ... α-(1-hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl ester ... 2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid β-(dimethylamino)ethyl ester …
Matched Iupac: … 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate …
Matched Description: … A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia. …
Matched Salts cas: … 5870-29-1
Matched Categories: … Mydriatics and Cycloplegics ... Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … CICLOPENTOLATO AL 1 % ... Ak-pentolate ... CYCLON 1% …
Investigational
Matched Synonyms: … 2-thiophenecarboxylic acid, 5-((1e)-2-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-propen ... acid ... -1-yl)- …
Matched Iupac: … acid ... 5-[(1E)-2-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)prop-1-en-1-yl]thiophene-2-carboxylic …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Receptors, Retinoic Acid, agonists …
Natural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography. Interferon alpha proteins are mainly involved in innate immune response against viral infection. They come in 13...
Investigational
Matched Description: … Of these, IFN-α2 and IFN-α14 are glycosylated. ... Multiferon consists of the 6 major subtypes are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. ... They come in 13 subtypes that are called IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Products: … CILFERON A ... Roferon-A "Roche" 3 Mio I.E./0,5 ml - Injektionslösung in einer Fertigspritze …
Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated heparin. It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. Reviparin has a molecular weight of 3.9 kDa. It was developed by Abbott laboratories and in 2009, reviparin presented an orphan...
Approved
Investigational
Matched Description: … [A32021] It was developed by Abbott laboratories and in 2009, reviparin presented an orphan drug designation ... [A32019] It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. ... Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated …
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … CLIVARIN 5726 IE A XA/ML ... CLIVARODI 17178 A XA/ML …
Investigational
Matched Synonyms: … 8-[(1-methyl-1H-pyrazol-4-yl)amino]imidazo[1,2-a]pyridin-3-yl]ethynyl]- ... -4-yl)amino)imidazo[1,2-a]pyridin-3-yl)ethynyl)benzamide ... Benzamide, N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-[2-[ …
Matched Iupac: … -1H-pyrazol-4-yl)amino]imidazo[1,2-a]pyridin-3-yl}ethynyl)benzamide ... N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-(2-{8-[(1-methyl …
Investigational
Matched Synonyms: … Arsenenous acid, sodium salt (1:1) ... Arsenious acid, sodium salt ... Arsenious acid, monosodium salt …
Experimental
Matched Synonyms: … Coenzyme A, desulfo …
Matched Name: … Desulfo-coenzyme A
Matched Iupac: … dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acid
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Enzymes and Coenzymes …
An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids.
Experimental
Matched Synonyms: … Sparsomycin A
Matched Description: … but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids ... An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … (R)-3-hydroxydecanoyl-coenzyme A
Matched Iupac: … ethyl}carbamoyl)-2,2-dimethylpropoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid
Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Synonyms: … 2-(3-[4-(3-chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one …
Matched Iupac: … 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one …
Matched Description: … , or insomnia, which are commonly associated with SSRI and SNRI therapy. ... [A181180] It is used in adults and has been shown to be comparable in efficacy to other drugs such as ... Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … TRITTICO A.C 150 ... Ag-trazodone ... Apo-trazodone Tablets 50mg …
Investigational
Matched Synonyms: … KINASE ERBB-2, ERBB2, HER2)) FUSED ON BOTH HEAVY CHAINS (1-447, 1''-447'') VIA A (G4S)3 LINKER (448- ... -AMINO ACID LINKER) FUSION PROTEIN WITH LIPOCALIN 2 (HUMAN MU ... (S228>P,F234>A,L235>A) IMMUNOGLOBULIN G4-KAPPA (CHIMERIC HUMAN-MUS MUSCULUS, ANTI-(RECEPTOR TYROSINE-PROTEIN …
Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Investigational
Matched Synonyms: … Tienchi Ginseng (Constituent of American Ginseng, Asian Ginseng, and Tienchi Ginseng) …
Matched Description: … It is not an approved drug. ... Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. …
Investigational
Matched Synonyms: … Phosphonic acid, p-(1-hydroxy-2-oxo-3-piperidinyl)- …
Matched Name: … (1-Hydroxy-2-oxopiperidin-3-yl)phosphonic acid
Matched Iupac: … (1-hydroxy-2-oxopiperidin-3-yl)phosphonic acid
Displaying drugs 776 - 800 of 5418 in total