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Displaying drugs 776 - 800 of 5460 in total
Tomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC).
Investigational
Matched Synonyms: … 6'-((6-Amino-4-pyrimidinyl)amino)-8'-methyl-2'H-spiro(cyclohexane-1,3'-imidazo(1,5-a)pyridine)-1',5'- …
Matched Iupac: … 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2',5'-dihydro-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine ... ]-1',5'-dione …
Matched Description: … With Advanced TNBC and HCC). ... Tomivosertib is under investigation in clinical trial NCT03318562 (A PD Study of Oral eFT508 in Subjects …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID) …
Matched Iupac: … 5-(dimethylamino)naphthalene-1-sulfonic acid
Investigational
Matched Synonyms: … 1-(carboxymethylthio)tetradecane ... Acetic acid, 2-(tetradecylthio)- …
Matched Name: … Tetradecylthioacetic acid
Matched Categories: … Fatty Acids ... Compounds used in a research, industrial, or household setting …
Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine receptor inhibitor (SNRIs) in the...
Approved
Investigational
Matched Synonyms: … 2-(3-[4-(3-chlorophenyl)-1-piperazinyl]propyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one …
Matched Iupac: … 2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one …
Matched Description: … , or insomnia, which are commonly associated with SSRI and SNRI therapy. ... [A181180] It is used in adults and has been shown to be comparable in efficacy to other drugs such as ... Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … TRITTICO A.C 150 ... Ag-trazodone ... Apo-trazodone Tablets 50mg …
A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
Approved
Nutraceutical
Matched Synonyms: … Vitamin J …
Matched Description: … It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and ... A basic constituent of lecithin that is found in many plants and animal organs. …
Matched Salts cas: … 67-48-1
Matched Mixtures name: … Classic Swiss One 10 Multivitamin and Mineral Tab ... B-complex With Vitamin C, Biotin, Folic Acid ... Revit Multi-vitamins and Minerals …
Matched Categories: … Salicylic Acid and Derivatives ... Vitamins ... Vitamin B Complex …
Experimental
Matched Synonyms: … Coenzyme A, desulfo …
Matched Name: … Desulfo-coenzyme A
Matched Iupac: … dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acid
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Enzymes and Coenzymes …
An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids.
Experimental
Matched Synonyms: … Sparsomycin A
Matched Description: … but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids ... An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … (R)-3-hydroxydecanoyl-coenzyme A
Matched Iupac: … ethyl}carbamoyl)-2,2-dimethylpropoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid
A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Approved
Experimental
Matched Synonyms: … 1-Amino-4-carboxybenzene ... Aminobenzoic acid ... 4-aminobenzoic acid
Matched Name: … Aminobenzoic acid
Matched Iupac: … 4-aminobenzoic acid
Matched Description: … A member of the vitamin B complex. ... It used to be common in sunscreening agents until found to also be a sensitizer. …
Matched Salts cas: … 138-84-1
Matched Mixtures name: … Presun 15 Lotion ... Multi B Complex Plus 500mg Vitamin C Tablets ... Neutral C + Coenzyme Q10 Plus Vitamins & Minerals …
Matched Categories: … Emollients and Protectives ... Vitamins ... Vitamin B Complex ... 4-Aminobenzoic Acid ... Acids, Carbocyclic …
An ergot derivative that is a congener of lysergic acid diethylamide. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the...
Approved
Matched Synonyms: … 1-Methyllysergic acid butanolamide ... 1-Methyl-D-lysergic acid butanolamide ... 1-Methyl-dextro-lysergic acid (+)-1-hydroxy-2-butylamide …
Matched Iupac: … (15),2,9,12(16),13-pentaene-4-carboxamide ... (4R,7R)-N-(1-hydroxybutan-2-yl)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1
Matched Description: … An ergot derivative that is a congener of lysergic acid diethylamide. ... Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin ... It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has …
Matched Salts cas: … 129-49-7 …
Matched Categories: … Ergot Alkaloids and Derivatives ... Lysergic Acid
Investigational
Matched Synonyms: … 8-[(1-methyl-1H-pyrazol-4-yl)amino]imidazo[1,2-a]pyridin-3-yl]ethynyl]- ... -4-yl)amino)imidazo[1,2-a]pyridin-3-yl)ethynyl)benzamide ... Benzamide, N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-[2-[ …
Matched Iupac: … -1H-pyrazol-4-yl)amino]imidazo[1,2-a]pyridin-3-yl}ethynyl)benzamide ... N-[3-(1-cyano-1-methylethyl)-5-(4-methyl-1H-imidazol-1-yl)phenyl]-2-fluoro-4-methyl-5-(2-{8-[(1-methyl …
IMT504, a non-CpG 24-mer oligodeoxynucleotide, is an immunomodulatory oligonucleotide currently being investigated as a rabies vaccine.
Investigational
Matched Synonyms: … DNA, D(P-THIO)(T-C-A-T-C-A-T-T-T-T-G-T-C-A-T-T-T-T-G-T-C-A-T-T) ... PyNTTTTGT class of oligodeoxynucleotide with a 24-base single chain composed of nucleotide sequence 5 …
Matched Description: … investigated as a rabies vaccine. ... IMT504, a non-CpG 24-mer oligodeoxynucleotide, is an immunomodulatory oligonucleotide currently being …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … (2S)-1-acetylpyrrolidine-2-carboxylic acid ... (S)-1-acetylpyrrolidine-2-carboxylic acid ... 1-acetylproline …
Matched Iupac: … (2S)-1-acetylpyrrolidine-2-carboxylic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
Approved
Investigational
Matched Synonyms: … 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin ... 1-butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocin ... deamino-2-O-methyltyrosine-1-carbaoxytocin …
Matched Iupac: … (2S)-2-{[(2S)-1-[(3R,6S,9S,12S,15S)-12-[(2S)-butan-2-yl]-9-(2-carbamoylethyl)-6-(carbamoylmethyl)-15- ... [(4-methoxyphenyl)methyl]-5,8,11,14,17-pentaoxo-1-thia-4,7,10,13,16-pentaazacycloicosane-3-carbonyl]pyrrolidin …
Matched Description: … It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction ... Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Oxytocin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … KARPAVER 100 MCG/1 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... KARPAVER 100 MCG/1 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... PABAL 100 MCG/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 1 AMPUL …
Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography.
Approved
Withdrawn
Matched Synonyms: … Iopanoic acid ... Iodopanoic acid ... Acidum iopanoicum …
Matched Name: … Iopanoic acid
Matched Iupac: … 2-[(3-amino-2,4,6-triiodophenyl)methyl]butanoic acid
Matched Description: … Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography. …
Matched Categories: … iopanoic acid ... Compounds used in a research, industrial, or household setting …
Investigational
Matched Synonyms: … 4-piperidinecarboxylic acid, 1-((3-chloro-2-fluorophenyl)methyl)-4-((3-fluoro-6-((5-methyl-1h-pyrazol ... Aurora a kinase inhibitor ly3295668 ... )-2-methyl-, (2r,4r)-,4-piperidinecarboxylic acid
Matched Iupac: … -yl}methyl)-2-methylpiperidine-4-carboxylic acid ... (2R,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-4-({3-fluoro-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridin-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Synonyms: … Glucopyranosyl Lipid A Stable Emulsion …
Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. The vaccine comprises two antigens - the other being recombinant stabilized RSV A prefusion F antigen - which have been expressed in Chinese hamster ovary cell lines and then purified...
Approved
Matched Synonyms: … RSV subgroup A stabilized prefusion F protein …
Matched Name: … Recombinant stabilized RSV A prefusion F antigen …
Matched Description: … ] - which have been expressed in Chinese hamster ovary cell lines and then purified and lyophilized. ... [L48066] Abrysvo was first approved by the FDA in May 2023 for use in patients ≥60 years of age, and ... virus vaccine, adjuvanted] (Arexvy), Abrysvo is reconstituted with sterile water prior to injection and
Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. Phenol is also used as an oral analgesic or anesthetic in products...
Approved
Experimental
Matched Synonyms: … Acide phénique ... Carbolic acid ... Phenic Acid
Matched Description: … Phenol is an antiseptic and disinfectant. ... Phenol has been used to disinfect skin and to relieve itching. ... Phenol is a toxic compound whose vapours are corrosive to the skin, eyes, and respiratory tract. …
Matched Mixtures name: … Major Camphor and Phenol ... Poison Oak and Ivy ... CAMPHOR (SYNTHETIC) and PHENOL …
Matched Categories: … Phenol and Derivatives ... Antiseptics and Disinfectants ... Compounds used in a research, industrial, or household setting …
Matched Products: … Castellani Paint 1.5% ... Pain A Lay ... Rx Act Sore Throat …
A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Synonyms: … O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3
Matched Iupac: … (10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin ... -1,3(7),8-trien-12-one ... -6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca …
Matched Description: … Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... Etoposide acts primarily in the G2 and S phases of the cell cycle. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... UGT1A1 Substrates with a Narrow Therapeutic Index ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Products: … N/A ... LASTET 100 MG KAPSUL, 10 ADET ... LASTET 100 MG ENJEKTABL, 1 ADET …
N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Matched Synonyms: … Melanowhite-A ... (2s)-2-acetylamino-3-(4-hydroxyphenyl)propanoic acid ... (+)-(2s)-2-(acetylamino)-3-(4-hydroxyphenyl)propanoic acid
Matched Iupac: … (2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid
Matched Description: … [DB00135] is a non-essential amino acid with a polar side group. ... N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor ... It is typically administered as a source of nutritional support where oral nutrition is inadequate or …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... AMINOVEN INFANT 10% …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs that are Mainly Renally Excreted ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Synonyms: … 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsäuredimethylester …
Matched Iupac: … 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … developed with slower onsets and longer durations of action. ... [A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature ... [A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been …
Matched Mixtures name: … Seaford Nifedipine and Lidocaine Hydrochloride Cream …
Matched Categories: … atenolol and nifedipine ... nifedipine and diuretics ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... Beta blocking agents and calcium channel blockers …
Matched Products: … NIFEDIPIN ACIS 10MG RETARD ... NIFEDIPIN ACIS 20MG RETARD ... NIFEDIPIN AL 10
Experimental
Matched Name: … L-Alpha-Phosphatidyl-Beta-Oleoyl-Gamma-Palmitoyl-Phosphatidylethanolamine …
Matched Iupac: … ]phosphinic acid ... (2-aminoethoxy)[(2R)-2-[(9E,12E)-hexadeca-9,12-dienoyloxy]-3-[(8E,16E)-octadeca-8,12,16-trienoyloxy]propoxy …
INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase Reverse Transcriptase (Htert), Invac-1 in Chronic Lymphocytic Leukemia).
Investigational
Matched Synonyms: … Invac-1, a double stranded dna plasmid vaccine construct encoding ubiquitin-human telomerase reverse ... Human telomerase reverse transcriptase (htert) dna vaccine invac-1
Matched Name: … INVAC-1
Matched Description: … INVAC-1 is under investigation in clinical trial NCT03265717 (DNA Plasmid Encoding a Modified Human Telomerase ... Reverse Transcriptase (Htert), Invac-1 in Chronic Lymphocytic Leukemia). …
An essential amino acid that is required for the production of histamine.
Investigational
Nutraceutical
Matched Synonyms: … (S)-a-Amino-1H-imidazole-4-propanoic acid ... (S)-α-amino-1H-Imidazole-4-propanoic acid ... (S)-alpha-amino-1H-Imidazole-4-propanoic acid
Matched Iupac: … (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid
Matched Description: … An essential amino acid that is required for the production of histamine. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... AA-Ven …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Essential ... Proteinogenic Amino Acids
Displaying drugs 776 - 800 of 5460 in total