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Displaying drugs 776 - 800 of 1351 in total

1-(O-Carboxy-Phenylamino)-1-Deoxy-D-Ribulose-5-Phosphate

Experimental
Matched Name: … 1-(O-Carboxy-Phenylamino)-1-Deoxy-D-Ribulose-5-Phosphate …

2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate)

Experimental
Matched Name: … 2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate) …

Lipoic acid

A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Synonyms: … Thioctic acid D-form …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …

[N-(BENZYLOXYCARBONYL)AMINO](4-AMIDINOPHENYL)METHANE-PHOSPHONATE

Experimental
Matched Name: … [N-(BENZYLOXYCARBONYL)AMINO](4-AMIDINOPHENYL)METHANE-PHOSPHONATE …

Bucladesine

Experimental
Matched Synonyms: … dibutyryl adenosine 3',5'-cyclic phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Acacia

Acacia allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Plants and plant parts, gum, acacia or arabic acacia senegal …

1,​2-​Dioleoyl-​sn-​glycero-​3-​phospho-​L-​serine

Investigational
Matched Synonyms: … L-serine, 2,3-bis((1-oxo-9-octadecenyl)oxy)propyl hydrogen phosphate (ester), (r-(z,z))- …

Cefadroxil

Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
Approved
Vet approved
Withdrawn
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … VOCEFA FORTE ... CEFFORD FORTE ... OPICEF FORTE …

2'-O-Methyl-3'-Methyl-3'-Deoxy-Arabinofuranosyl-Thymine-5'-Phosphate

Experimental
Matched Name: … 2'-O-Methyl-3'-Methyl-3'-Deoxy-Arabinofuranosyl-Thymine-5'-Phosphate …

(2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate

Experimental
Matched Name: … (2R)-2-Acetamido-3-(octadecyloxy)propyl 2-(methylsulfanyl)ethyl hydrogen phosphate …

4-(6-CHLORO-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL) BUTYL PHOSPHATE

Experimental
Matched Name: … 4-(6-CHLORO-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL) BUTYL PHOSPHATE …

4-Carbamoyl-1-Beta-D-Ribofuranosyl-Imidazolium-5-Olate-5'-Phosphate

Experimental
Matched Name: … 4-Carbamoyl-1-Beta-D-Ribofuranosyl-Imidazolium-5-Olate-5'-Phosphate …

Lavender oil

Approved
Experimental
Matched Synonyms: … Lavandula vulgaris flowering top oil …

Trastuzumab

Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein (HER2). It is used as a treatment of human epidermal...
Approved
Investigational
Matched Description: … Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and ... that the overexpression or gene amplification of HER2 has been found in about 20–30% of breast cancers and ... cancer, it is the second biosimilar approved in the U.S. for the treatment of cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … HERZUMA® 440MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION ... Herzuma (trastuzumab) 150 mg Powder for Concentrate for Solution for Infusion ... HERZUMA® 150MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION …

(1Z)-2-HYDROXY-3-OXOHEX-1-EN-1-YL DIHYDROGEN PHOSPHATE

Experimental
Matched Name: … (1Z)-2-HYDROXY-3-OXOHEX-1-EN-1-YL DIHYDROGEN PHOSPHATE …

Cresol

Cresol is a hydroxytoluene that can be extracted naturally from coal tar or made synthetically. Pure cresol is a mixture of ortho-, meta-, and para- isomers. Cresols are precursors or synthetic intermediates to various other compounds and materials, including plastics, pesticides, pharmaceuticals, disinfectants, and dyes. Ingestion of cresol induces toxicity...
Approved
Matched Description: … concentrations normally found in the environment however, cresols do not pose any significant risk for ... pain, and/or vomiting. ... Ingestion of cresol induces toxicity in humans and can lead to burning of the mouth and throat, abdominal …
Matched Products: … Formo Cresol ... Buckleys Formo Cresol …

Polatuzumab vedotin

Polatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells. The drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl (mc-vc-PAB) that covalently attaches MMAE to...
Approved
Investigational
Matched Description: … [L6658] Polatuzumab vedotin was granted accelerated FDA approval on June 10, 2019 [A254936] and was ... human CD79b (polatuzumab), MMAE, and protease-cleavable linker called maleimidocaproyl-valine-citrulline-p-aminobenzyloxycarbonyl ... drug consists of three components - a humanized immunoglobulin G1 (IgG1) monoclonal antibody specific for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 140MG ... POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 30MG ... POLIVY 140mg Powder For Concentrate For Solution For Infusion …

Trastuzumab emtansine

Trastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to ImmunoGen's cell-killing agent, DM1. T-DM1 combines two strategies-- anti-HER2 activity and targeted intracellular delivery of the potent anti-microtubule agent, DM1 (a maytansine derivative)--to produce cell cycle arrest and apoptosis....
Approved
Investigational
Matched Description: … Trastuzumab emtansine is marketed under the brand name Kadcyla and is indicated for use in HER2-positive ... , metastatic breast cancer patients who have already used taxane and/or trastuzumab for metastatic disease ... First that trastuzumab emtansine and trastuzumab cannot be interchanged. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … KADCYLA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/VIAL ... KADCYLA POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 160MG/VIAL ... Kadcyla 160 mg powder for concentrate for solution for infusion …

Siltuximab

Siltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology. Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6). Its use is indicated for the treatment...
Approved
Investigational
Matched Description: … Its use is indicated for the treatment of adult patients with multicentric Castleman's disease (MCD) ... who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative. ... Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Sylvant 400mg Powder for Concentrate for Solution for Infusion ... Sylvant 100mg Powder for Concentrate for Solution for Infusion ... SYLVANT POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/VIAL …

ABSK-012

Investigational
Matched Synonyms: … 3-(5-cyano-4-(cyclopropylamino)pyridin-2-yl)-1-(6-formyl-5-((4-methyl-2-oxopiperazin-1-yl)methyl)pyridin ... N′-[5-Cyano-4-(cyclopropylamino)-2-pyridinyl]-N-[6-formyl-5-[(4-methyl-2-oxo-1-piperazinyl)methyl]-2- ... Urea, N′-[5-cyano-4-(cyclopropylamino)-2-pyridinyl]-N-[6-formyl-5-[(4-methyl-2-oxo-1-piperazinyl)methyl …
Matched Iupac: … 3-[5-cyano-4-(cyclopropylamino)pyridin-2-yl]-1-{6-formyl-5-[(4-methyl-2-oxopiperazin-1-yl)methyl]pyridin …

Brentuximab vedotin

Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Description: … This demonstrates meaningful progress in treatment for patients affected by this disease.[L1739] ... Lymphoma may begin anywhere in the body and can spread to nearby lymph nodes. ... was revised with a boxed warning of a condition known as progressive multifocal leukoencephalopathy and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ADCETRIS 50 MG (POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION) ... POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG/VIAL ... Adcetris 50mg, powder for concentrate for solution for infusion …

Polyvinyl alcohol

Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol. It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing. Polyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes .
Approved
Matched Description: … It has varying roles in commercial and industrial applications such as papermaking, textiles, and printing …
Matched Mixtures name: … Murine Tears for Dry Eyes ... Murine Plus for Dry Eyes Redness Relief …
Matched Products: … Liquifilm Forte 3% ... Artificial Tears for Dry Eyes …

Simoctocog alfa

Simoctocog alfa is a recombinant B-domain deleted (BDD) rFVIII produced in genetically modified human embryonic kidney (HEK) 293F cells. The harvested product is concentrated and purified by a series of chromatography steps. It is an antihemorrhagic agent used as a replacement therapy in individuals with Haemophilia A who lack the...
Approved
Matched Description: … The harvested product is concentrated and purified by a series of chromatography steps. ... + A3-C1-C2 whereas the B-domain, present in the full-length plasma-derived FVIII, has been deleted and ... haemophilia A are predisposed to episodes of recurrent bleeding [L1115], simoctocog alfa can be administered for …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Nuwiq 250IU Powder for Solution for Injection ... Nuwiq 500IU Powder for Solution for Injection ... Nuwiq 1000IU Powder for Solution for Injection …

Oxaliplatin

Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride...
Approved
Investigational
Matched Description: … leucovorin, known as the FOLFOX regimen, for the treatment of colorectal cancer. ... Ongoing trials have also shown promising results for oxaliplatin use in nonHodgkin’s lymphoma, breast ... cancer, mesothelioma, and non-small cell lung cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … hovid Oxaliplatin 50mg Powder for Concentrate for Solution for Infusion ... HOVID OXALIPLATIN POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 50MG/VIAL ... hovid Oxaliplatin 100mg Powder for Concentrate for Solution for Infusion …

(3-Formyl-but-3-Enyl)-Phosphonic Acid

Experimental
Matched Name: … (3-Formyl-but-3-Enyl)-Phosphonic Acid …
Displaying drugs 776 - 800 of 1351 in total