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Displaying drugs 776 - 800 of 6401 in total
Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as Colchicum autumnale, or "autumn crocus." Its use was first approved by the FDA in 1961. Colchicine is used in the treatment of gout flares and Familial Mediterranean fever, and prevention of major cardiovascular events....
Approved
Matched Iupac: … N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.0^{2,7}]hexadeca-1(16),2(7),3,5,11,14-hexaen-10-yl …
Matched Description: … Colchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum …
Matched Products: … COLCHICINA COMPRIMIDO X 0.5 MG ... Colctab 1 mg Tabletten ... Colchanova 1 mg Tabletten …
Black walnut allergenic extract is used in allergenic testing.
Approved
Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence. It is unique amongst overactive bladder treatment options in that, unlike other treatments such as solifenacin and darifenacin, it lacks significant antimuscarinic activity, which is...
Approved
Matched Iupac: … 2-(2-amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)phenyl]acetamide …
Matched Description: … Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of ... Mirabegron has a comparatively favorable adverse effect profile as compared to other available treatment …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Adrenergic beta-3 Receptor Agonists ... Selective Beta 3-adrenergic Agonists …
Nylidrin, also known as buphenine belongs to the category of drugs called vasodilators, which relax blood vessels and increase blood flow. Nylidrin is a peripheral vasodilator. Some studies show the evidence of improving cognitive impairment in selected individuals, such as geriatric patients with mild to moderate symptoms of cognitive, emotional...
Approved
Matched Iupac: … 4-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]propyl}phenol …
Matched Description: … Nylidrin is a peripheral vasodilator. …
Matched Categories: … 2-Amino-1-Phenylethanol Derivatives …
Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. It was approved on May 29, 2013, for the treatment of melanoma with V600E or V6000K mutation. It was also used for metastatic non-small cell lung cancer with the same mutation. In May 2018, Tafinlar (dabrafenib),...
Approved
Investigational
Matched Iupac: … N-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzene-1- …
Matched Description: … Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK ... [L41955] In May 2018, Tafinlar (dabrafenib), in combination with Mekinist ([DB08911]), was approved …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... B-Raf serine-threonine kinase (BRAF) inhibitors ... Organic Anion Transporter 1 Inhibitors ... Proto-Oncogene Proteins B-raf, antagonists & inhibitors ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Iupac: … 3,7-dimethyl-1-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Description: … Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties ... [A226410, A226415, A226455] More recently, PTX has been suggested as a possible treatment for COVID-19 ... [A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced …
Matched Mixtures name: … Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5% …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Compounds used in a research, industrial, or household setting …
Matched Products: … PENTOXIFILINA TABLETAS DE LIBERACIÓN PROLONGADA X 400MG …
Black-eyed pea allergenic extract is used in allergenic testing.
Approved
Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Nisoldipine may be used in alone...
Approved
Matched Synonyms: … isobutyl methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Iupac: … 3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Corifollitropin alfa, also known as Elonva is used in women undergoing fertility treatment to stimulate the development of more than one mature egg (oocyte) at a time in the ovaries. This drug used together with a gonadotropin-releasing hormone (GnRH) antagonist, a type of medicine also used in fertility treatments. Elonva...
Approved
Investigational
Matched Description: … Corifollitropin alfa is produced by a method known as ‘recombinant DNA technology’. ... In July 2014, Merck announced the receipt of a Complete Response Letter (CRL) from the U.S. ... undergoing fertility treatment to stimulate the development of more than one mature egg (oocyte) at a
Matched Products: … ELONVA 150 MCG/0,5 ML ENJEKSIYONLUK COZELTI, 1 ADET ... ELONVA 100 MCG/0,5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... ELONVA 150 MCG/0,5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
Bisabolol, or more formally α-(−)-bisabolol or also known as levomenol, (-)-alpha-Bisabolol is found in fats and oils. (-)-alpha-Bisabolol is isolated from essential oil of Matricaria chamomilla (German chamomile) (-)-alpha-Bisabolol belongs to the family of Sesquiterpenes. These are terpenes with three consecutive isoprene units.
Approved
Experimental
Matched Iupac: … (2S)-6-methyl-2-[(1S)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol …
Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … a low-level toxicity. ... In addition, PEG is available as a bowel preparation for colonoscopy procedures and as a laxative [L1788 ... [L1787] Polyethylene glycol 400 (PEG 400) is a low-molecular-weight grade of polyethylene glycol with …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated from certain brown seaweed (Phacophycae) via alkaline extraction. It is present in cell walls of brown algae where it forms a viscous gel when binding with water. Alginic acid is a linear polymer consisted...
Approved
Investigational
Matched Synonyms: … (Alginate)n+1 ... (Alginate)n
Matched Description: … Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated ... It is present in cell walls of brown algae where it forms a viscous gel when binding with water. ... Alginic acid is a linear polymer consisted of L-glucuronic acid and D-mannuronic acid residues connected …
Matched Salts cas: … 9005-38-3
Matched Mixtures name: … SUSPENSION ORAL CON SABOR A MENTA ... SUSPENSION ORAL CON SABOR A MENTA ... GAVISCON® TABLETAS MASTICABLES SABOR A MENTA …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Bos taurus skin or pelt is used in allergenic testing.
Approved
Tyropanoic acid is a radiocontrast agent used in cholecystography, the X-ray diagnosis of gallstones under the trade names include Bilopaque, Lumopaque, Tyropaque, and Bilopac. The molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in bones, which results in a visible image .
Approved
Matched Iupac: … 2-[(3-butanamido-2,4,6-triiodophenyl)methyl]butanoic acid …
Matched Description: … Tyropanoic acid is a radiocontrast agent used in cholecystography, the X-ray diagnosis of gallstones ... bones, which results in a visible image [L1608]. ... The molecule contains three heavy iodine atoms which obstruct X-rays in the same way as the calcium in …
Matched Salts cas: … 7246-21-1
Matched Categories: … Compounds used in a research, industrial, or household setting ... X-Ray Contrast Media, Iodinated ... Watersoluble, Hepatotropic X-Ray Contrast Media …
Fibrinogen concentrate (human) is a hematological agent. It works by replacing a certain protein in the blood that helps with blood clotting. Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. It is a physiological substrate for three enzymes: plasmin, factor XIIIa and...
Approved
Matched Description: … Fibrinogen (factor I) is a soluble plasma glycoprotein with a molecular weight of about 340 kDa. ... Fibrinogen concentrate (human) is a hematological agent. ... It works by replacing a certain protein in the blood that helps with blood clotting. …
Matched Mixtures name: … BERIPLAST-P COMBI SET 3 ML TROMBİN ÇÖZELTİSİ VE 1 ML FİBRİNOJEN ÇÖZELTİSİ İÇEREN FİBRİN YAPIŞTIRICI ... , SET 1 (2 İĞNE+2 ENJEKTÖR) VE SET 2 (2 İĞNE +2 ENJEKTÖR+1 ENJEKTÖR KLİPSİ+2 BİRLEŞTİRME PARÇASI+ 4 APLİKASYON ... TISSEEL 2 ML KULLANIMA HAZIR ENJEKTÖR 1 ADET …
Matched Products: … FIBRINOGENO TIM 3 UMANO IMMUNO ... FIBRYGA 1 g Pulver und Lösungsmittel zur Herstellung einer Injektions-/Infusionslösung …
Vaborbactam is a β-lactamase inhibitor based on a cyclic boronic acid pharmacophore. It has been used in trials investigating the treatment of bacterial infections in subjects with varying degrees of renal insufficiency. In August 2017, a combination antibacterial therapy under the market name Vabomere was approved by the FDA for...
Approved
Investigational
Matched Iupac: … 2-[(3R,6S)-2-hydroxy-3-[2-(thiophen-2-yl)acetamido]-1,2-oxaborinan-6-yl]acetic acid …
Matched Description: … In August 2017, a combination antibacterial therapy under the market name Vabomere was approved by the ... Vaborbactam is a β-lactamase inhibitor based on a cyclic boronic acid pharmacophore. …
Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment of for mild to moderate atopic dermatitis. This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 years old and...
Approved
Investigational
Matched Iupac: … 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzonitrile …
Matched Description: … Crisaborole is a novel oxaborole approved by FDA on December 14, 2016 as Eucrisa, a topical treatment ... improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 ... It reduces the local inflammation in the skin and prevents further exacerbation of the disease with a
Matched Products: … Staquis Topical Ointment 2% …
Approved
Investigational
Matched Products: … FEIBA 1000 U IV INFUZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET ... FEIBA 500 U IV INFUZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET …
Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout...
Approved
Matched Synonyms: … 2-(3-cyano-4-isobutoxyphenyl)-4-methyl- 1,3-thiazole-5-carboxylic acid …
Matched Iupac: … 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carboxylic acid …
Matched Description: … Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. ... a post-market clinical study (the CARES trial) where there was an increased risk of cardiovascular ( ... [A230548] In February 2019, a black box warning for febuxostat was added, based on the findings of …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Carpinus caroliniana pollen is the pollen of the Carpinus caroliniana plant. Carpinus caroliniana pollen is mainly used in allergenic testing.
Approved
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to...
Approved
Investigational
Matched Synonyms: … 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid ... 4'-((4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid ... 4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid …
Matched Iupac: … 4'-{[4-methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl}-[1,1'-biphenyl ... ]-2-carboxylic acid …
Matched Description: … Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 ... causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a
Matched Salts cas: … 515815-47-1
Matched Mixtures name: … CARDIOCAP A 80/5 ... CARDIOCAP A 80/5 ... XIFEN A®80 /10 MG …
Matched Categories: … Angiotensin II Type 1 Receptor Blockers ... Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 2-Ring ... Angiotensin II Type 2 Receptor Blockers …
Quinidine is a D-isomer of quinine present in the bark of the Cinchona tree and similar plant species. This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.[A38016,A250050] Quinidine is considered the first antiarrhythmic drug (class Ia) and is moderately efficacious in the acute...
Approved
Investigational
Matched Synonyms: … (S)-(6-Methoxy-quinolin-4-yl)-((2R,5R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol ... (R)-(6-Methoxyquinolin-4-yl)((3S,4R,7S)-3-vinylquinuclidin-7-yl)methanol ... α-(6-methoxy-4-quinolyl)-5-vinyl-2-quinuclidinemethanol …
Matched Iupac: … (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol …
Matched Description: … Quinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species ... This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication. ... A phenomenon known as “quinidine syncope” was first described in the 1950s, characterized by syncopal …
Matched Salts cas: … 7054-25-3 ... 1668-99-1
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Compounds used in a research, industrial, or household setting ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour taste. From the medical point of view, it is used as alkalinizing...
Approved
Investigational
Matched Iupac: … trisodium 2-hydroxypropane-1,2,3-tricarboxylate …
Matched Description: … Like citric acid, it has a sour taste. …
Matched Salts cas: … 6132-04-3
Matched Mixtures name: … Solucodan-H ... ORS B PLUS ... Cytra-2
Matched Categories: … Compounds used in a research, industrial, or household setting …
Approved
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Compounds used in a research, industrial, or household setting …
Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection prior to autologous transplantation. Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic cancers - high-dose chemotherapy regimens destroy cancerous blood cells, which are then replaced via infusion of the patient's...
Approved
Investigational
Matched Description: … L48136] Similar in mechanism to the previously approved [plerixafor], motixafortide is an inhibitor of C-X-C ... Motixafortide is a cyclic peptide hematopoietic stem cell mobilizer used to improve stem cell collection ... Motif Chemokine Receptor 4 (CXCR4), a protein that helps to anchor stem cells to bone marrow matrix. …
Displaying drugs 776 - 800 of 6401 in total