Displaying drugs 776 - 800 of 1067 in total
Vestronidase alfa
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … sequence as human beta-glucuronidase (GUS) [FDA Label]. ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble ... Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … sequence as human beta-glucuronidase (GUS) [FDA Label]. ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble ... Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Spheramine
Investigational
Matched Synonyms: … Allogeneic human retinal pigment epithelial cells on gelatin microcarriers …
PAT-SM6
Investigational
Matched Synonyms: … Recombinant human monoclonal IgM antibody targeting glucose regulated protein 78 …
Respigam
Investigational
Matched Synonyms: … Respiratory syncytial virus immune globulin intravenous (human) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
ATYR-1940
Investigational
Matched Synonyms: … Human recombinant histidyl-t-RNA synthetase (residues 2-506) …
Pucotenlimab
Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours. It is being investigated in other cancers.
Approved
Investigational
Matched Synonyms: … Immunoglobulin g4 (252-theronine,306-proline,432-alanine), anti-(human programmed cell death 1) (human-mus ... musculus monoclonal hx008 .gamma.4-chain), disulfide with human-mus musculus monoclonal hx008 .kappa …
Pregabalin
Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational
Matched Description: … [A173995] It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other ... [A187190,L7066] Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … PREGABALIN BASICS 25MG ... PREGABALIN BASICS 50MG ... PREGABALIN BASICS 75MG …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … PREGABALIN BASICS 25MG ... PREGABALIN BASICS 50MG ... PREGABALIN BASICS 75MG …
Nemvaleukin alfa
Investigational
Matched Synonyms: … -chain (human) ... 2 receptor α-chain (human) ... human interleukin 2 fragment (1-59), variant (Cys125>Ser51), fused via peptidyl linker (60GG61) to human …
Opebacan
Investigational
Matched Synonyms: … 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN) ... 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN REDUCED) …
Ontamalimab
Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Investigational
Matched Synonyms: … human IgG2 monoclonal antibody directed against the mucosal addressin cell adhesion molecule ... human IgG2 anti-monoclonal antibody directed against mucosal addressin cell adhesion molecule (MAdCAM …
Matched Description: … Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tamsulosin
Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.[Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.[Label] Antagonism of these receptors leads to relaxation of smooth muscle in...
Approved
Investigational
Matched Description: … in the prostate and bladder, where these receptors are most common. ... Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect ... [Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Categories: … tamsulosin and tadalafil ... tamsulosin and dutasteride ... tamsulosin and solifenacin ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … TAMSULOSIN BASICS 0.4MG ... TAMSULOSIN BASICS 0.4 MG ... TAMSULOSIN BASICS 0.4MG HK …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Categories: … tamsulosin and tadalafil ... tamsulosin and dutasteride ... tamsulosin and solifenacin ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … TAMSULOSIN BASICS 0.4MG ... TAMSULOSIN BASICS 0.4 MG ... TAMSULOSIN BASICS 0.4MG HK …
Sevirumab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI-(CYTOMEGALOVIRUS) (HUMAN MONOCLONAL EV2-7 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Human Umbilical Cord Mesenchymal Stem Cells
Stem cells obtained from amniotic fluid, the umbilical cord (UC), and placenta are gaining in popularity. Stem cells from the umbilical cord offer several advantages, including: non-invasive collection procedures, more hearty and steady growth than bone-marrow derived stem cells (they can maintain a steady doubling time (DT) over up to...
Investigational
Matched Synonyms: … Human Umbilical Cord Wharton’s Jelly-derived Mesenchymal Stem Cells …
Matched Name: … Human Umbilical Cord Mesenchymal Stem Cells …
Matched Description: … steady growth than bone-marrow derived stem cells (they can maintain a steady doubling time (DT) over ... class II and its co-stimulatory ligands like CD40, CD80, and CD86. ... UC mesenchymal cells derived from Wharton’s jelly are the most studied and offer more stable and better …
Matched Name: … Human Umbilical Cord Mesenchymal Stem Cells …
Matched Description: … steady growth than bone-marrow derived stem cells (they can maintain a steady doubling time (DT) over ... class II and its co-stimulatory ligands like CD40, CD80, and CD86. ... UC mesenchymal cells derived from Wharton’s jelly are the most studied and offer more stable and better …
Torapsel
Torapsel has been used in trials studying the prevention of Ischemia Reperfusion Injury.
Investigational
Matched Synonyms: … (HUMAN CONSTANT REGION) ... 42-89-GLYCOPROTEIN (HUMAN CLONE PMT21:PL85 P-SELECTIN GLYCOPROTEIN LIGAND-1) FUSION PROTEIN WITH IMMUNOGLOBULIN …
Human cord blood hematopoietic progenitor cell
Human cord blood hematopoietic progenitor cells consist of hematopoietic progenitor cells, monocytes, lymphocytes, and granulocytes from human cord blood. They are used during allogeneic unrelated and related hematopoietic stem cell transplantation procedures in patients with disorders affecting the hematopoietic system that are inherited, acquired, or result from myeloablative treatment. Human...
Approved
Matched Name: … Human cord blood hematopoietic progenitor cell …
Matched Description: … lymphocytes, and granulocytes from human cord blood. ... Human umbilical cord is a rich source of hematopoietic stem cells and progenitor cells that are capable ... marrow transplantation; it allows shorter time to transplant and tolerance of 1–2 human leukocyte antigen …
Matched Description: … lymphocytes, and granulocytes from human cord blood. ... Human umbilical cord is a rich source of hematopoietic stem cells and progenitor cells that are capable ... marrow transplantation; it allows shorter time to transplant and tolerance of 1–2 human leukocyte antigen …
Allogeneic human pancreatic islets of Langerhans
Investigational
Matched Name: … Allogeneic human pancreatic islets of Langerhans …
Amatuximab
Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(mesothelin) (human-mouse monoclonal MORAb-009 heavy chain), disulfide with human-mouse …
Matched Description: … Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian ... Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian ... Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
RBIO-101
RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein.
Investigational
Matched Synonyms: … recombinant adeno-associated virus vector encoding human CYP4V2 protein …
Matched Description: … RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein. …
Matched Description: … RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein. …
VG161
VG161 is an oncolytic virus therapy under investigation for the treatment of cholangiocarcinoma.
Investigational
Matched Synonyms: … Recombinant human IL12/15-PDL1B HSV-1 oncolytic virus Injection …
Teriparatide
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … Teriparatide recombinant human …
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] ... [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Calcium-Regulating Hormones and Agents ... Parathyroid Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] ... [A251395] Teriparatide is used in the treatment of osteoporosis in men and women.[L42590, L42595] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Calcium-Regulating Hormones and Agents ... Parathyroid Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Mirococept
Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct that regulates the over-production of complement at the cell surface, which occurs in inflammation. It consists...
Investigational
Matched Synonyms: … myristoylated recombinant SCR1-3 of human complement reseptor type I …
Matched Description: … in recombinant bacteria and modified with a membrane-targeting amphiphilic peptide based on the naturally ... APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct …
Matched Description: … in recombinant bacteria and modified with a membrane-targeting amphiphilic peptide based on the naturally ... APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct …
Velmanase alfa
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Recombinant Human Alpha Mannosidase …
Matched Description: … sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Recombinant Human Lysosomal alpha-Mannosidase …
Matched Description: … sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Recombinant Human Lysosomal alpha-Mannosidase …
Pegilodecakin
Pegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
Investigational
Matched Synonyms: … INTERLEUKIN 10 (SYNTHETIC HUMAN), DIMER, N-TERMINAL 5-KILODALTON PEGYLATED …
Matched Categories: … Biological Factors ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Biological Factors ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Displaying drugs 776 - 800 of 1067 in total