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Displaying drugs 8151 - 8175 of 11838 in total

Pseudouridine-5'-Monophosphate

Experimental
Matched Name: … Pseudouridine-5'-Monophosphate …
Matched Iupac: … {[(2R,3S,4R,5S)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic …

Alpha-Adenosine Monophosphate

Experimental
Matched Iupac: … {[(2R,3S,4R,5S)-5-(6-amino-7H-purin-7-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …

PPL-100

Investigational
Matched Iupac: … methyl N-[(1S)-1-{[(5S)-6-hydroxy-5-[N-(2-methylpropyl)4-aminobenzenesulfonamido]hexyl]carbamoyl}-2,2 …

JZP-386 free base

JZP-386 is a deuterium-containing analog of sodium oxybate. Its safety, pharmacokinetics and pharmacodynamics were evaluated in clinical trial NCT02215499.
Investigational

Quisinostat

Quisinostat has been used in trials studying the treatment of Lymphoma, Neoplasms, Myelodysplastic Syndromes, and Advanced or Refractory Leukemia.
Investigational
Matched Iupac: … N-hydroxy-2-[4-({[(1-methyl-1H-indol-3-yl)methyl]amino}methyl)piperidin-1-yl]pyrimidine-5-carboxamide …

Glycocholic acid

The glycine conjugate of cholic acid. It acts as a detergent to solubilize fats for absorption and is itself absorbed.
Experimental
Investigational

Eniluracil

Eniluracil, which was previously under development by GlaxoSmithKline (GSK), is being developed by Adherex to enhance the therapeutic value and effectiveness of 5-fluorouracil (5-FU), one of the world’s most widely-used oncology agents. 5-FU is widely used in the U.S. and is often first or second line therapy for a variety...
Investigational
Matched Synonyms: … 5-Ethynyluracil …
Matched Iupac: … 5-ethynyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Description: … fluorouracil (5-FU), one of the world’s most widely-used oncology agents. 5-FU is widely used in the ... GlaxoSmithKline (GSK), is being developed by Adherex to enhance the therapeutic value and effectiveness of 5- ... Eniluracil could improve 5-FU by increasing its effectiveness, reducing its side effects and/or making …

Ostrea edulis shell

Ostrea edulis shell is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental

1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE

Experimental

Tonabacase

Investigational

Erteberel

Erteberel is an estrogen receptor beta agonist that has been used in trials studying the treatment of Benign Prostatic Hyperplasia.
Experimental
Investigational

(S)-wiskostatin

Experimental
Matched Name: … (S)-wiskostatin …
Matched Iupac: … (2S)-1-(3,6-dibromo-9H-carbazol-9-yl)-3-(dimethylamino)propan-2-ol …

SC45647

Experimental

SC12267

SC12267 is a novel, small molecule agent from the class of DMARDs (disease modifying anti-rheumatic drug) for the therapy of autoimmune diseases such as rheumatoid arthritis or multiple sclerosis. Through highly selective inhibition of pyrimidine biosynthesis, it controls the growth of rapidly proliferating cells, especially of lymphocytes, which are important...
Investigational

Nelipepimut-S

Investigational
Matched Synonyms: … Nelipepimut S ... Nelipepimut-S …
Matched Name: … Nelipepimut-S …

Sonepcizumab

A humanized monoclonal antibody directed against sphingosine 1-phosphate (S1P) with potential antiangiogenic and antineoplastic activities. Upon administration, sonepcizumab binds S1P, which may result in the inhibition of tumor angiogenesis. S1P is the extracellular ligand for the G protein-coupled lysophospholipid receptor EDG-1 (endothelial differentiation gene-1).
Investigational

Sibrotuzumab

Sibrotuzumab is a humanized monoclonal antibody directed against fibroblast activation protein (FAP). It is used to treat cancer.
Investigational

Sarafloxacin

Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.
Vet approved
Withdrawn
Matched Iupac: … 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid …

Sapanisertib

Sapanisertib has been used in trials studying the treatment of HCC, Solid Tumor, Gliosarcoma, Liver Cancer, and Glioblastoma, among others.
Investigational
Matched Iupac: … 5-[4-amino-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzoxazol-2-amine …

Sarpogrelate

Sarpogrelate has been investigated for the treatment of Diabetes Mellitus, Diabetic Nephropathy, Coronary Artery Disease, and Renal Insufficiency, Chronic.
Investigational
Matched Iupac: … 4-{[1-(dimethylamino)-3-{2-[2-(3-methoxyphenyl)ethyl]phenoxy}propan-2-yl]oxy}-4-oxobutanoic acid …

Selurampanel

Selurampanel has been investigated in Adrenocortical Adenoma and Sarcoma, Endometrial Stromal.
Investigational
Matched Iupac: … N-[6-(1-methyl-1H-pyrazol-5-yl)-2,4-dioxo-7-(propan-2-yl)-1,2,3,4-tetrahydroquinazolin-3-yl]methanesulfonamide …

Sotrastaurin

Sotrastaurin has been used in trials studying the basic science and treatment of Uveal Melanoma, Richter Syndrome, Prolymphocytic Leukemia, Recurrent Mantle Cell Lymphoma, and Recurrent Small Lymphocytic Lymphoma, among others.
Investigational
Matched Iupac: … 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-2,5-dihydro-1H-pyrrole-2,5-dione …
Matched Salts cas: … 908351-31-5 …

Sulforaphane

Sulforaphane is under investigation for the treatment of Autism Spectrum Disorder. It is a naturally occurring isothiocyanate found in high concentration in a variety of broccoli.
Investigational

Sitafloxacin

Experimental
Investigational
Matched Iupac: … -1,4-dihydroquinoline-3-carboxylic acid) trihydrate ... bis(7-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-4-oxo …

Sacubitrilat

A metabolite of LCZ696 with neprilysin inhibitory activity.
Experimental
Matched Iupac: … (2R,4S)-5-{[1,1'-biphenyl]-4-yl}-4-(3-carboxypropanamido)-2-methylpentanoic acid …
Displaying drugs 8151 - 8175 of 11838 in total