Displaying drugs 801 - 825 of 1155 in total
Ofatumumab
Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Synonyms: … HuMax-CD20 ... HuMax-CD20, 2F2 …
Matched Description: … It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic ... mouse and hybridoma technology. ... In February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Proteins ... Blood Proteins …
Matched Description: … It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic ... mouse and hybridoma technology. ... In February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Proteins ... Blood Proteins …
Avizakimab
Avizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care).
Investigational
Matched Synonyms: … Immunoglobulin g1 (251-tyrosine,253-threonine,255-glutamic acid), anti-(human interleukin 21) (human-mus ... musculus monoclonal bos161721 .gamma.1-chain), disulfide with human-mus musculus monoclonal bos161721 …
Obinepitide
Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS. In obinepitide,...
Investigational
Matched Synonyms: … (34-L-glutamine)pancreatic hormone (human) …
Matched Description: … Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which ... These hormones are known to play a role in the regulation of food intake and appetite in man as satiety …
Matched Description: … Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which ... These hormones are known to play a role in the regulation of food intake and appetite in man as satiety …
Human adenovirus b serotype 7
Human adenovirus b serotype 7 is a vaccine.
Approved
Matched Synonyms: … Human Adenovirus B Serotype 7 Strain 55142 …
Matched Name: … Human adenovirus b serotype 7 …
Matched Description: … Human adenovirus b serotype 7 is a vaccine. …
Matched Name: … Human adenovirus b serotype 7 …
Matched Description: … Human adenovirus b serotype 7 is a vaccine. …
Pegylated Recombinant Human Arginase I
Pegylated Recombinant Human Arginase I is under investigation in clinical trial NCT03455140 (A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)).
Investigational
Matched Synonyms: … Pegylated recombinant human arginase i bct-100 …
Matched Name: … Pegylated Recombinant Human Arginase I …
Matched Description: … Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)). ... Pegylated Recombinant Human Arginase I is under investigation in clinical trial NCT03455140 (A Study …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Proteins …
Matched Name: … Pegylated Recombinant Human Arginase I …
Matched Description: … Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)). ... Pegylated Recombinant Human Arginase I is under investigation in clinical trial NCT03455140 (A Study …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Proteins …
EF-022
EF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic and anti-angiogenic activities.
Investigational
Matched Synonyms: … Modified vitamin D binding protein ... Modified Vitamin D Binding Protein Macrophage Activator …
Matched Description: … and anti-angiogenic activities. ... EF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic …
Matched Description: … and anti-angiogenic activities. ... EF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic …
Mecasermin
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … Human somatomedin C ... INSULIN-LIKE GROWTH FACTOR I (HUMAN) ... RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-I …
Matched Description: … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a ... The rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the ... gene for human IGF-1. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Human Insulin-like Growth Factor Analogs ... Recombinant Human Insulin-like Growth Factor-1 ... Proteins …
Matched Description: … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a ... The rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the ... gene for human IGF-1. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Human Insulin-like Growth Factor Analogs ... Recombinant Human Insulin-like Growth Factor-1 ... Proteins …
Efmoroctocog alfa
Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It...
Approved
Investigational
Matched Synonyms: … Antihemophilic factor (recombinant, FC fusion protein) ... Antihemophilic Factor (Recombinant BDD), FC Fusion Protein ... Coagulation factor VIII recombinant immunoglubulin g1 fusion protein …
Matched Description: … is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. ... other hemorrhages that cause chronic pain and disability to patients [A31551, A31552]. ... Patients with this disorder are more susceptible to recurrent bleeding episodes and excessive bleeding …
Matched Categories: … Human Antihemophilic Factors …
Matched Description: … is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. ... other hemorrhages that cause chronic pain and disability to patients [A31551, A31552]. ... Patients with this disorder are more susceptible to recurrent bleeding episodes and excessive bleeding …
Matched Categories: … Human Antihemophilic Factors …
Bevifimod
Bevifimod is under investigation in clinical trial NCT01749787 (Safety Study of PRTX-100 With Methotrexate or Leflunomide to Treat Active Rheumatoid Arthritis).
Investigational
Matched Synonyms: … STAPHYLOCOCCAL PROTEIN A …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Bacterial Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Bacterial Proteins …
Cry5B
Cry5B is a pore-forming crystal protein produced by and derived from the soil bacterium Bacillus thuringiensis. With demonstrated anthelmintic properties, it has been investigated in the treatment of parasitic intestinal infections.[A259372, A259377]
Investigational
Matched Synonyms: … Bacillus thuringiensis Cry5B Protein …
Matched Description: … Cry5B is a pore-forming crystal protein produced by and derived from the soil bacterium _Bacillus thuringiensis …
Matched Description: … Cry5B is a pore-forming crystal protein produced by and derived from the soil bacterium _Bacillus thuringiensis …
Pegzilarginase
Pegzilarginase is under investigation in clinical trial NCT02488044 (A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency).
Investigational
Matched Synonyms: … Optimised human arginase I ... Co-ArgI-PEG modified human arginase I …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Fecal microbiota
Fecal microbiota, given either as a rectal transplant or in an oral formulation of live spores, is an FDA-approved option to prevent the recurrence of Clostridioides difficile infection (CDI) in patients given an antibacterial treatment for recurrent CDI.[A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases...
Approved
Investigational
Matched Synonyms: … Donor human stool ... Donor human stool spores (ethanol treated) …
Matched Description: … Human fecal matter is then tested for a panel of transmissible pathogens and processed with methods aimed ... Recurrent CDI has a high risk of mortality and a high failure rate. ... [A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases requiring …
Matched Description: … Human fecal matter is then tested for a panel of transmissible pathogens and processed with methods aimed ... Recurrent CDI has a high risk of mortality and a high failure rate. ... [A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases requiring …
Polistes annularis venom protein
Polistes annularis venom protein is an extract of Polistes annularis venom. Polistes annularis venom protein is used in allergenic testing.
Approved
Matched Synonyms: … red paper wasp venom protein …
Matched Name: … Polistes annularis venom protein …
Matched Description: … Polistes annularis venom protein is used in allergenic testing. ... Polistes annularis venom protein is an extract of Polistes annularis venom. …
Matched Categories: … Bee and Wasp Venom …
Matched Name: … Polistes annularis venom protein …
Matched Description: … Polistes annularis venom protein is used in allergenic testing. ... Polistes annularis venom protein is an extract of Polistes annularis venom. …
Matched Categories: … Bee and Wasp Venom …
Vespula pensylvanica venom protein
Vespula pensylvanica venom protein is an extract of Vespula pensylvanica venom. Vespula pensylvanica venom protein is used in allergenic testing.
Approved
Matched Synonyms: … western yellow jacket venom protein …
Matched Name: … Vespula pensylvanica venom protein …
Matched Description: … Vespula pensylvanica venom protein is used in allergenic testing. ... Vespula pensylvanica venom protein is an extract of Vespula pensylvanica venom. …
Matched Categories: … Bee and Wasp Venom …
Matched Name: … Vespula pensylvanica venom protein …
Matched Description: … Vespula pensylvanica venom protein is used in allergenic testing. ... Vespula pensylvanica venom protein is an extract of Vespula pensylvanica venom. …
Matched Categories: … Bee and Wasp Venom …
Influenza A virus subtype H3N2 haemagglutinin, recombinant
Approved
Matched Synonyms: … Recombinant haemagglutinin protein-strain A (H3N2) …
Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media
Umbilical-cord derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and anti-inflammatory properties. In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally regarded as less immunogenic. The condition medium (CM) derived from these MSCs has also been implicated...
Investigational
Matched Synonyms: … Allogeneic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media ... Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Matched Name: … Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Matched Description: … derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and ... In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally …
Matched Name: … Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Matched Description: … derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and ... In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally …
Baloramotide
Investigational
Matched Synonyms: … Recombinant NY-ESO-1 protein ... Cancer testis antigen ny-eso-1 (recombinant human) ... Glycyl-l-prolyl-human cancer/testis antigen 1 (autoimmunogenic cancer/testis antigen ny-eso-1, l antigen …
Ramipril
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to …
Matched Categories: … Protease Inhibitors ... ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... ramipril and felodipine ... ramipril and amlodipine …
Matched Products: … DELIX PROTECT 10MG TABL ... DELIX PROTECT 10 MG TABLET, 90 ADET ... DELIX PROTECT 10 MG TABLET, 28 ADET …
Matched Categories: … Protease Inhibitors ... ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... ramipril and felodipine ... ramipril and amlodipine …
Matched Products: … DELIX PROTECT 10MG TABL ... DELIX PROTECT 10 MG TABLET, 90 ADET ... DELIX PROTECT 10 MG TABLET, 28 ADET …
Losartan
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Description: … available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and ... [L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored …
Matched Mixtures name: … Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... losartan and diuretics ... losartan and amlodipine …
Matched Products: … COLIBS ... COZAAR PROTECT 50MG ... LORZAAR PROTECT 50MG …
Matched Mixtures name: … Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide ... Losartan Potassium and Hydrochlorothiazide …
Matched Categories: … Angiotensin II receptor blockers (ARBs) and diuretics ... Angiotensin II receptor blockers (ARBs) and calcium channel blockers ... losartan and diuretics ... losartan and amlodipine …
Matched Products: … COLIBS ... COZAAR PROTECT 50MG ... LORZAAR PROTECT 50MG …
Human adenovirus e serotype 4 strain cl-68578 antigen
Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine.
Approved
Matched Synonyms: … Human Adenovirus Serotype 4 Strain Cl-68578 ... Human Adenovirus E Serotype 4 Strain Cl-68578 ... Human Adenovirus Serotype 4 Vaccine Strain Cl-68578 …
Matched Name: … Human adenovirus e serotype 4 strain cl-68578 antigen …
Matched Description: … Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine. …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 4 Vaccine …
Matched Name: … Human adenovirus e serotype 4 strain cl-68578 antigen …
Matched Description: … Human adenovirus e serotype 4 strain cl-68578 antigen is a vaccine. …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 4 Vaccine …
DR-01
DR-01 is a monoclonal antibody directed against human CD94.
Investigational
Matched Synonyms: … Human anti-CD94 IgG1 monoclonal antibody (non-fucosylated) …
Matched Description: … DR-01 is a monoclonal antibody directed against human CD94. …
Matched Description: … DR-01 is a monoclonal antibody directed against human CD94. …
Cephalexin
Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Description: … [A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. …
Matched Products: … GRANULOS PARA SUSPENSION ORAL ... OSPEXINA 250 MG/5 ML GRANULOS PARA SUSPENSION ORAL …
Matched Products: … GRANULOS PARA SUSPENSION ORAL ... OSPEXINA 250 MG/5 ML GRANULOS PARA SUSPENSION ORAL …
ATL-2502
ATL-2502(Colal-Pred) is an old drug (prednisolone metasulphobenzoate, a steroid) with a new delivery system that releases the medication only in the colon. Releasing the drug directly into the colon reduces the potential for significant side effects often experienced with steroid drugs. Colal-Pred is being studied for use in ulcerative colitis.
Investigational
Matched International brands: … Colal-Pred …
Matched Description: … system that releases the medication only in the colon. ... Colal-Pred is being studied for use in ulcerative colitis. ... ATL-2502(Colal-Pred) is an old drug (prednisolone metasulphobenzoate, a steroid) with a new delivery …
Matched Description: … system that releases the medication only in the colon. ... Colal-Pred is being studied for use in ulcerative colitis. ... ATL-2502(Colal-Pred) is an old drug (prednisolone metasulphobenzoate, a steroid) with a new delivery …
Thrombomodulin Alfa
Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism.
Approved
Investigational
Matched Synonyms: … Thrombomodulin (human 498-amino acid fragment) …
Matched Description: … It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Membrane Proteins …
Matched Description: … It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential ... Thrombomodulin Alfa is a novel, recombinant and soluble thrombomodulin (ART-123). ... treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular thromboembolism …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Membrane Proteins …
Adenovirus type 7 vaccine live
Approved
Matched Synonyms: … Human adenovirus B serotype 7 strain 55142 antigen …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 7 Vaccine …
Matched Mixtures name: … Adenovirus Type 4 and Type 7 Vaccine, Live …
Matched Categories: … Live Human Adenovirus Type 7 Vaccine …
Displaying drugs 801 - 825 of 1155 in total